POLA1

General Information

Gene Name : POLA1
Gene ID : ENSG00000101868.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLA1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLA1	ENSG00000101868.10	18.73	17.88	18.30	ENCSR000AEF
HepG2	POLA1	ENSG00000101868.10	9.70	15.78	12.74	ENCSR985KAT
K562	POLA1	ENSG00000101868.10	21.61	23.98	22.80	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLA1 is not avaliable on ENCORE database.

Proteins bound to RNA

POLA1 RNA is bound by 33 proteins.

CanvasJS.com

eCLIP assay for POLA1 is not avaliable on ENCORE database.

33 proteins are bound to POLA1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chrX	24762604	24762621	+	intron-Distal	5.70574	400.00000	HepG2	DKC1
chrX	24762621	24762631	+	intron-Distal	5.95155	400.00000	HepG2	DKC1
chrX	24762631	24762670	+	intron-Distal	5.47799	400.00000	HepG2	DKC1
chrX	24735470	24735606	+	CDS	5.41343	27.64176	K562	UCHL5
chrX	24820004	24820103	+	intron-Distal	5.12535	13.38240	K562	EIF4G2
chrX	24718270	24718392	+	intron-Distal	6.26300	13.13056	K562	QKI
chrX	24735753	24735829	+	CDS	3.89914	10.90977	K562	ZNF622
chrX	24757502	24757614	+	CDS	4.71038	10.80414	HepG2	BCLAF1
chrX	24735701	24735757	+	CDS	4.28933	10.57284	K562	UCHL5
chrX	24827972	24828090	+	CDS,intron-Proximal	5.78901	9.95947	K562	SF3B4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 90 entries

eCLIP assay for POLA1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLA1 is not available on ENCORE database.
167 RBPs can affect the levels of POLA1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for POLA1 is not available on ENCORE database.

167 RBPs can affect the gene expression of POLA1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLA1	ENSG00000101868.6	255.01730	855.86190	-1.74680	57.48540	55.82970	HepG2	ZNF622
POLA1	ENSG00000101868.6	322.41290	1017.59730	-1.65820	52.13630	50.67770	HepG2	SRFBP1
POLA1	ENSG00000101868.6	176.83770	702.65690	-1.99040	45.47070	43.89840	HepG2	TIAL1
POLA1	ENSG00000101868.6	199.58360	775.58420	-1.95830	37.26220	35.05730	HepG2	SF3B1
POLA1	ENSG00000101868.6	229.06530	771.93570	-1.75270	34.28080	32.48890	HepG2	RPLP0
POLA1	ENSG00000101868.6	293.13400	732.00510	-1.32030	31.91010	30.20810	HepG2	CKAP4
POLA1	ENSG00000101868.6	333.39660	949.71350	-1.51030	31.33820	29.62300	HepG2	PUF60
POLA1	ENSG00000101868.6	251.07880	789.01520	-1.65190	30.02720	28.41980	HepG2	BOP1
POLA1	ENSG00000101868.6	285.73350	708.99120	-1.31110	29.04530	27.45740	HepG2	TRIM56
POLA1	ENSG00000101868.6	201.15960	760.44700	-1.91850	28.87200	27.10870	HepG2	SUPV3L1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 217 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLA1 is not available on ENCORE database.

15 RBPs can affect the splicing of POLA1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	POLA1	ENSG00000101868.6	chrX	+	24873443	24873598	24861662	24861794	24906122	24906239	0.28100	0.00000	0.00000	included	K562	SRSF1
SE	POLA1	ENSG00000101868.6	chrX	+	24721367	24721464	24717541	24717666	24722505	24722586	-0.36100	0.00000	0.00001	excluded	K562	SRSF1
SE	POLA1	ENSG00000101868.6	chrX	+	24744097	24744172	24742451	24742568	24745049	24745188	-0.47900	0.00000	0.00000	excluded	K562	U2AF1
SE	POLA1	ENSG00000101868.6	chrX	+	24735000	24735088	24734478	24734571	24735406	24735608	-0.33800	0.00001	0.00022	excluded	K562	PUS1
SE	POLA1	ENSG00000101868.6	chrX	+	24744097	24744172	24742451	24742568	24745049	24745188	-0.33700	0.00001	0.00036	excluded	K562	AGGF1
SE	POLA1	ENSG00000101868.6	chrX	+	24735000	24735088	24734478	24734571	24735406	24735608	-0.35400	0.00004	0.00236	excluded	K562	AKAP8L
SE	POLA1	ENSG00000101868.6	chrX	+	24735000	24735088	24734478	24734571	24735406	24735608	-0.19400	0.00004	0.01569	excluded	K562	NPM1
SE	POLA1	ENSG00000101868.6	chrX	+	24744097	24744172	24742451	24742568	24745049	24745188	-0.33300	0.00005	0.00295	excluded	K562	AKAP8L
SE	POLA1	ENSG00000101868.6	chrX	+	24744097	24744172	24742451	24742568	24745049	24745188	-0.31000	0.00006	0.00368	excluded	K562	UTP18
SE	POLA1	ENSG00000101868.6	chrX	+	24873443	24873598	24861662	24861794	24906122	24906239	0.09600	0.00007	0.02088	included	K562	LARP4

Showing 1 to 10 of 36 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLA1

General Information

Functions

Localization

Domains (AlphaFold: POLA1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLA1 is not avaliable on ENCORE database.

33 proteins are bound to POLA1 RNA:

eCLIP assay for POLA1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLA1 is not available on ENCORE database.

167 RBPs can affect the gene expression of POLA1 :

The Knockdown/knockout RNA-Seq assay for POLA1 is not available on ENCORE database.

15 RBPs can affect the splicing of POLA1 :

The Knockdown/knockout RNA-Seq assay for POLA1 is not avaliable on ENCORE database.