ACAT1

General Information

Gene Name       : ACAT1
Gene ID             : ENSG00000075239.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ACAT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ACAT1ENSG00000075239.1367.1560.1863.67ENCSR000AEF
HepG2ACAT1ENSG00000075239.1379.1392.6085.86ENCSR985KAT
K562ACAT1ENSG00000075239.1368.9268.4768.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ACAT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ACAT1 RNA is bound by 14 proteins.  







eCLIP assay for ACAT1 is not avaliable on ENCORE database.





14 proteins are bound to ACAT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11108018045108018189+3'-UTR,CDS4.349894.69071HepG2GRWD1
chr11108018126108018216+3'-UTR5.3397810.73726K562NOLC1
chr11108004975108005044+3'-UTR,CDS,intron-Proximal3.542328.19964HepG2BCLAF1
chr11108013160108013281+3'-UTR,CDS,intron-Proximal3.561456.88667K562BUD13
chr11108018046108018169+3'-UTR,CDS3.148643.39148K562LIN28B
chr11108013205108013270+3'-UTR,CDS3.932433.02572K562SND1
chr11108004561108004666+3'-UTR,CDS,intron-Proximal3.267227.30556K562YBX3
chr11108013163108013206+3'-UTR,CDS,intron-Proximal3.434678.16183HepG2BCLAF1
chr11108012375108012427+3'-UTR,CDS4.8224417.52604HepG2BCLAF1
chr11108009733108009768+3'-UTR,CDS3.676663.87469HepG2BCLAF1
chr11108004975108005044+3'-UTR,CDS,intron-Proximal3.498835.20121K562GRWD1
chr11108002633108002682+3'-UTR,CDS,intron-Proximal4.250608.45138K562DDX3X
chr11108012371108012430+3'-UTR,CDS,intron-Proximal3.572676.11414K562BUD13
chr11108018136108018203+3'-UTR6.4611534.26611HepG2SUB1
chr11107992290107992406+5'-UTR,CDS,intron-Proximal3.805715.32728HepG2DDX3X
chr11107992290107992321+5'-UTR3.707849.54328K562YBX3
chr11107992321107992345+5'-UTR,CDS3.218968.74043K562YBX3
chr11107992294107992406+5'-UTR,CDS,intron-Proximal4.1970327.44964K562DDX3X
chr11108005750108005893+CDS,intron-Distal,intron-Proximal3.306956.67026K562KHSRP
chr11107992382107992443+CDS,intron-Proximal4.240927.87148HepG2PRPF8
chr11108014714108014773+CDS3.915933.18234K562BUD13
chr11108009624108009654+CDS,intron-Proximal4.256603.71570HepG2BCLAF1
chr11108016928108017021+CDS,intron-Proximal3.930569.50935HepG2BCLAF1
chr11108005868108005898+CDS,intron-Distal,intron-Proximal3.171633.94979HepG2BCLAF1
chr11108017996108018082+CDS,intron-Proximal3.634606.60490HepG2BCLAF1
chr11108017021108017085+CDS4.5915210.13662HepG2BCLAF1
chr11108016926108017063+CDS,intron-Proximal3.287235.85200K562BUD13
chr11108017029108017087+CDS,intron-Proximal5.287978.18798K562UCHL5
chr11108017030108017069+CDS3.920633.11168K562ZNF622
chr11108016929108017087+CDS,intron-Proximal3.062205.48645K562GRWD1
chr11107995619107995703+intron-Distal3.264805.01093HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ACAT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ACAT1 is not available on ENCORE database.

  • 117 RBPs can affect the levels of ACAT1.  








The Knockdown/knockout RNA-Seq assay for ACAT1 is not available on ENCORE database.





117 RBPs can affect the gene expression of ACAT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ACAT1ENSG00000075239.92753.040702134.059400.367303.062702.07050HepG2ABCF1
ACAT1ENSG00000075239.91132.950101499.21620-0.404106.505605.65380HepG2ACO1
ACAT1ENSG00000075239.9828.324301084.70060-0.389002.305201.35020HepG2AKAP8
ACAT1ENSG00000075239.91014.227401506.21170-0.5705010.752809.36460HepG2AKAP8L
ACAT1ENSG00000075239.91292.408101853.24870-0.520004.678303.67050HepG2ASCC1
ACAT1ENSG00000075239.91720.924502659.72190-0.6281016.3121014.89540HepG2AUH
ACAT1ENSG00000075239.9909.457201244.86610-0.452902.829301.92080HepG2BCLAF1
ACAT1ENSG00000075239.91291.938901990.13330-0.623308.262507.29560HepG2BOP1
ACAT1ENSG00000075239.92421.616301890.342900.357204.037903.12870HepG2CALR
ACAT1ENSG00000075239.91263.332701498.83240-0.246603.004302.31750HepG2CKAP4
ACAT1ENSG00000075239.9339.45880761.29770-1.165209.739808.34060HepG2CNOT7
ACAT1ENSG00000075239.91402.969501827.04870-0.381003.196402.46270HepG2CPSF6
ACAT1ENSG00000075239.91386.128901758.01870-0.342902.628501.55060HepG2CPSF7
ACAT1ENSG00000075239.91535.123001991.56140-0.375505.137304.30960HepG2CELF1
ACAT1ENSG00000075239.91797.824802141.26590-0.252203.677202.84250HepG2DAZAP1
ACAT1ENSG00000075239.91707.572801386.533500.300404.428403.40420HepG2DDX19B
ACAT1ENSG00000075239.9689.099401243.52200-0.8516012.8279011.49930HepG2DDX21
ACAT1ENSG00000075239.9966.337601408.48120-0.543503.913803.00920HepG2DDX55
ACAT1ENSG00000075239.91365.450101842.88690-0.432603.058502.41160HepG2DDX6
ACAT1ENSG00000075239.9820.366401254.70360-0.6130013.3100011.98840HepG2DNAJC2
ACAT1ENSG00000075239.9868.696601121.19860-0.368102.509701.45270HepG2EFTUD2
ACAT1ENSG00000075239.9756.998201771.84440-1.2269021.5076019.96260HepG2EIF2S1
ACAT1ENSG00000075239.9736.170601091.75430-0.568504.245903.14250HepG2EIF3D
ACAT1ENSG00000075239.9580.945901906.37640-1.7144028.0940026.07950HepG2EIF4B
ACAT1ENSG00000075239.91549.596702112.62090-0.447103.642802.70430HepG2EIF4G1
ACAT1ENSG00000075239.91370.801003053.71360-1.1555050.2729048.31410HepG2ETF1
ACAT1ENSG00000075239.9938.338801464.95060-0.642708.953907.47040HepG2EWSR1
ACAT1ENSG00000075239.9731.32240975.66820-0.415903.941902.51770HepG2FAM120A
ACAT1ENSG00000075239.91627.336802155.00550-0.405202.643201.88980HepG2FIP1L1
ACAT1ENSG00000075239.91050.558801542.31640-0.553903.685202.40060HepG2FUS
ACAT1ENSG00000075239.91479.639801975.41030-0.416903.408802.64620HepG2FXR1
ACAT1ENSG00000075239.91383.558701832.66170-0.405602.934202.25040HepG2G3BP1
ACAT1ENSG00000075239.9930.641401311.78910-0.495203.830602.62940HepG2GNB2L1
ACAT1ENSG00000075239.91073.232801431.28710-0.415406.294104.89560HepG2HDGF
ACAT1ENSG00000075239.9733.610301277.96400-0.8008011.6120010.43310HepG2HNRNPA1
ACAT1ENSG00000075239.91538.827801967.95790-0.354903.541002.50240HepG2HNRNPA2B1
ACAT1ENSG00000075239.91002.228701421.51360-0.504205.165404.24050HepG2HNRNPC
ACAT1ENSG00000075239.91296.683801669.83760-0.364904.812803.90070HepG2HNRNPF
ACAT1ENSG00000075239.91260.418401855.31820-0.557806.195905.18110HepG2HNRNPK
ACAT1ENSG00000075239.91477.840601950.48340-0.400307.942006.85400HepG2HNRNPL
ACAT1ENSG00000075239.91411.140201976.48580-0.486104.681003.88340HepG2HNRNPLL
ACAT1ENSG00000075239.9976.547401412.11430-0.532109.547408.47470HepG2HNRNPU
ACAT1ENSG00000075239.91371.988101644.32330-0.261202.005501.38180HepG2IGF2BP1
ACAT1ENSG00000075239.91274.529901442.42540-0.178501.939701.31240HepG2ILF2
ACAT1ENSG00000075239.91717.432602517.07120-0.551504.519603.44740HepG2LARP4
ACAT1ENSG00000075239.92452.513201987.213800.303401.887701.36140HepG2MATR3
ACAT1ENSG00000075239.9804.210501142.65120-0.506702.781701.72740HepG2METAP2
ACAT1ENSG00000075239.91205.163901744.63880-0.533705.704704.58150HepG2MSI2
ACAT1ENSG00000075239.91338.344302015.77140-0.590904.080602.89350HepG2MTPAP
ACAT1ENSG00000075239.91542.732502034.06880-0.398902.907202.25940HepG2NCBP2
ACAT1ENSG00000075239.91388.631202123.28300-0.6126011.037609.55390HepG2NOL12
ACAT1ENSG00000075239.92460.468501752.536900.489405.348804.32470HepG2NSUN2
ACAT1ENSG00000075239.9496.63450695.79380-0.486502.062901.31240HepG2PABPC1
ACAT1ENSG00000075239.91278.838701811.67760-0.502504.430803.52990HepG2PABPC4
ACAT1ENSG00000075239.91141.161501397.73270-0.292603.229202.32110HepG2PARN
ACAT1ENSG00000075239.91298.065201980.93420-0.6098011.1569010.07130HepG2PCBP1
ACAT1ENSG00000075239.9998.736401460.00350-0.547803.412902.26340HepG2PCBP2
ACAT1ENSG00000075239.9967.110401259.49050-0.381103.733202.88870HepG2PPIL4
ACAT1ENSG00000075239.91798.505901550.880700.213602.134701.44770HepG2PRPF4
ACAT1ENSG00000075239.91152.032402015.58690-0.8070022.6908021.41290HepG2PTBP1
ACAT1ENSG00000075239.91512.071002151.69450-0.5089012.9245011.84050HepG2PUM1
ACAT1ENSG00000075239.91519.390602150.09220-0.500907.206506.14170HepG2PUM2
ACAT1ENSG00000075239.9873.390901527.04040-0.8060022.0954020.66170HepG2PUS1
ACAT1ENSG00000075239.91190.324902183.11730-0.8750021.9294020.41470HepG2QKI
ACAT1ENSG00000075239.91024.488801408.86360-0.459602.046601.43170HepG2RAVER1
ACAT1ENSG00000075239.92034.449102552.34010-0.327204.385103.77240HepG2RBM22
ACAT1ENSG00000075239.91233.534601981.24870-0.6836011.4438010.13340HepG2RBM25
ACAT1ENSG00000075239.91126.756601549.57020-0.459703.846502.66310HepG2RBM27
ACAT1ENSG00000075239.9927.497601258.31780-0.440102.722101.67190HepG2RCC2
ACAT1ENSG00000075239.91785.342202243.22760-0.329405.013504.32110HepG2NELFE
ACAT1ENSG00000075239.91319.622801798.67500-0.446804.437403.60240HepG2RPLP0
ACAT1ENSG00000075239.9959.628601384.06800-0.528403.087402.09110HepG2RPS10
ACAT1ENSG00000075239.9834.077801062.28530-0.348902.696602.08850HepG2RPS19
ACAT1ENSG00000075239.91028.121101429.14380-0.475104.155403.18390HepG2RPS2
ACAT1ENSG00000075239.9540.766701075.02220-0.9913011.024209.61910HepG2RRP9
ACAT1ENSG00000075239.91786.574301257.541400.506507.919406.91360HepG2SAFB2
ACAT1ENSG00000075239.9839.199501066.23160-0.345402.236501.38760HepG2SERBP1
ACAT1ENSG00000075239.91275.421802098.64340-0.7185012.0236010.92880HepG2SF3B4
ACAT1ENSG00000075239.91151.707001466.49100-0.348605.448804.59740HepG2SMN1
ACAT1ENSG00000075239.91070.757001436.90260-0.424302.456501.55830HepG2SMNDC1
ACAT1ENSG00000075239.91516.432302882.77530-0.9268038.5203037.21500HepG2SRFBP1
ACAT1ENSG00000075239.92940.377002190.465200.424708.752908.01830HepG2SRSF1
ACAT1ENSG00000075239.91625.319502105.02430-0.373102.356301.44210HepG2SRSF3
ACAT1ENSG00000075239.91268.908102001.32880-0.6574015.5900014.27430HepG2SRSF5
ACAT1ENSG00000075239.91250.998701640.52580-0.391105.526904.59910HepG2SRSF7
ACAT1ENSG00000075239.91508.158501782.00480-0.240703.031502.45920HepG2SRSF9
ACAT1ENSG00000075239.93169.969002502.933500.340706.382605.66220HepG2SSB
ACAT1ENSG00000075239.91015.938302276.01180-1.1637051.7114049.63240HepG2SUCLG1
ACAT1ENSG00000075239.91387.342101809.15370-0.383004.322503.28610HepG2TIA1
ACAT1ENSG00000075239.91106.351401384.40240-0.323504.171003.50680HepG2TRIM56
ACAT1ENSG00000075239.91036.584401843.76230-0.8308011.8188010.49350HepG2U2AF1
ACAT1ENSG00000075239.9839.245302344.89800-1.482406.247804.69750HepG2U2AF2
ACAT1ENSG00000075239.9603.15230828.35090-0.457703.051202.25620HepG2UCHL5
ACAT1ENSG00000075239.9797.580601737.03490-1.1229041.3477039.32410HepG2UPF1
ACAT1ENSG00000075239.91116.100301677.04060-0.5875012.3629011.23610HepG2UTP3
ACAT1ENSG00000075239.91779.694801380.290600.366602.989302.23580HepG2XRN2
ACAT1ENSG00000075239.91038.290901530.50990-0.5598012.1393010.90030HepG2ZC3H8
ACAT1ENSG00000075239.92260.177403597.65650-0.6706010.291909.26930K562AQR
ACAT1ENSG00000075239.91617.135402292.07300-0.503203.962802.91680K562BOP1
ACAT1ENSG00000075239.91984.580302561.30600-0.368002.864601.42000K562BUD13
ACAT1ENSG00000075239.91689.090802122.63390-0.329602.796201.50920K562CIRBP
ACAT1ENSG00000075239.92239.076103346.96820-0.580003.392602.19330K562CNOT7
ACAT1ENSG00000075239.91856.294502437.17750-0.392804.752703.72920K562CPSF6
ACAT1ENSG00000075239.93899.207503093.804800.333704.908003.68880K562DKC1
ACAT1ENSG00000075239.91026.260401463.10860-0.511604.835903.61390K562EFTUD2
ACAT1ENSG00000075239.91518.900402276.88970-0.5840012.1839010.82910K562EIF2S2
ACAT1ENSG00000075239.91179.374701482.98360-0.330502.663801.85920K562EIF4A3
ACAT1ENSG00000075239.9973.591601335.49380-0.456005.887404.09540K562EIF4B
ACAT1ENSG00000075239.93419.823504389.75340-0.360205.703104.37680K562EIF4G2
ACAT1ENSG00000075239.91821.054302479.68080-0.445404.510703.41580K562FMR1
ACAT1ENSG00000075239.91375.655902101.71430-0.611406.805405.30650K562FTO
ACAT1ENSG00000075239.92033.170801554.302900.387402.333901.69230K562G3BP2
ACAT1ENSG00000075239.91627.040902326.94170-0.516206.537605.32110K562GPKOW
ACAT1ENSG00000075239.9890.140301700.36580-0.9337017.9689016.53100K562HNRNPC
ACAT1ENSG00000075239.92289.497203181.10670-0.474506.445804.76810K562HNRNPL
ACAT1ENSG00000075239.92046.611402530.38470-0.306103.732402.69330K562HNRNPU
ACAT1ENSG00000075239.91542.869001980.38550-0.360202.305201.39290K562IGF2BP2
ACAT1ENSG00000075239.91468.795801986.82110-0.435802.849801.89890K562KRR1
ACAT1ENSG00000075239.91614.659502271.33910-0.492306.252804.90810K562METAP2
ACAT1ENSG00000075239.92014.948702403.74370-0.254502.686001.88870K562MTPAP
ACAT1ENSG00000075239.91330.080201851.98060-0.477605.416104.03720K562PCBP2
ACAT1ENSG00000075239.91094.830301524.53370-0.477704.503703.30610K562PSIP1
ACAT1ENSG00000075239.93770.333204789.61270-0.345203.499502.58390K562PUF60
ACAT1ENSG00000075239.93955.776704991.62340-0.335505.138403.81270K562PUM2
ACAT1ENSG00000075239.93981.067502851.362400.481405.390804.66480K562PUS1
ACAT1ENSG00000075239.91480.750601939.14570-0.389103.641902.66590K562RBM22
ACAT1ENSG00000075239.91473.343501890.24550-0.359502.786401.40420K562RBM34
ACAT1ENSG00000075239.91958.485703345.05750-0.772303.669201.83110K562RBM39
ACAT1ENSG00000075239.91096.484101390.83210-0.343103.156402.09070K562RCC2
ACAT1ENSG00000075239.91969.983402635.26840-0.419805.858204.70600K562SF3A3
ACAT1ENSG00000075239.91579.100002212.86950-0.486804.226903.00470K562SF3B1
ACAT1ENSG00000075239.91062.829301616.41270-0.604905.361804.14440K562SF3B4
ACAT1ENSG00000075239.91357.383002006.39550-0.563806.364605.25130K562TARDBP
ACAT1ENSG00000075239.91624.700301935.38720-0.252402.160101.44420K562TIA1
ACAT1ENSG00000075239.91221.165801557.69750-0.351202.829801.87170K562TRIM56
ACAT1ENSG00000075239.91155.276601506.86200-0.383302.285801.30470K562U2AF1
ACAT1ENSG00000075239.91224.397601556.18280-0.345903.505302.60210K562U2AF2
ACAT1ENSG00000075239.92107.556302832.08540-0.426305.597404.61450K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ACAT1 is not available on ENCORE database.





15 RBPs can affect the splicing of ACAT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEACAT1ENSG00000075239.9chr11+108014709108014774108013163108013277108016928108017086-0.096000.005660.08352excludedHepG2U2AF1
SEACAT1ENSG00000075239.9chr11+108005868108005969108004947108005043108009624108009768-0.063000.000040.00068excludedK562AQR
SEACAT1ENSG00000075239.9chr11+108004947108005043108002633108002681108009624108009768-0.484000.007010.08014excludedK562PUS1
SEACAT1ENSG00000075239.9chr11+108014709108014774108013163108013277108016928108017086-0.053000.000390.01043excludedK562U2AF1
SEACAT1ENSG00000075239.9chr11+108005868108005969108004947108005043108009624108009768-0.067000.002750.05145excludedK562U2AF1
SEACAT1ENSG00000075239.9chr11+108014709108014774108013163108013277108016928108017086-0.078000.000590.02018excludedHepG2SF3A3
SEACAT1ENSG00000075239.9chr11+108014709108014774108013163108013277108016928108017086-0.063000.000030.00105excludedK562U2AF2
SEACAT1ENSG00000075239.9chr11+108005868108005969108004947108005043108009624108009768-0.077000.002530.04111excludedK562HNRNPC
MXEACAT1ENSG00000075239.9chr11+108004546108004664108004947108005043108002633108002681108005868108005968-0.119000.007660.072812includedK562DROSHA
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.128000.000150.010081includedK562LIN28B
MXEACAT1ENSG00000075239.9chr11+108004546108004660108004947108005043108002633108002681108009624108009768-0.107000.000160.001832includedK562AQR
MXEACAT1ENSG00000075239.9chr11+1080058681080059691080096241080097681080049471080050431080107911080109420.056000.000010.000221includedHepG2SFPQ
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.175000.000310.010161includedHepG2DDX55
MXEACAT1ENSG00000075239.9chr11+108005868108005969108009624108009768108004947108005043108010791108010942-0.132000.000060.002742includedHepG2DDX55
MXEACAT1ENSG00000075239.9chr11+108002633108002681108004546108004664107992293107992405108004947108005043-0.096000.000530.048402includedK562PUM1
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.123000.000520.012041includedK562HNRNPC
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.104000.000570.091971includedK562EXOSC5
MXEACAT1ENSG00000075239.9chr11+108002633108002681108004546108004664107992293107992405108004947108005043-0.139000.000000.000102includedK562PPIL4
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.176000.000000.000021includedHepG2NCBP2
MXEACAT1ENSG00000075239.9chr11+108005868108005969108009624108009768108004947108005043108010791108010942-0.086000.000900.086212includedHepG2XRCC6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ACAT1 is not avaliable on ENCORE database.