RIOK2

General Information

Gene Name : RIOK2
Gene ID : ENSG00000058729.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: RIOK2)

Not Available

Antibody Validation

View validation images for all RIOK2 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RIOK2	ENSG00000058729.10	19.23	15.62	17.43	ENCSR000AEF
HepG2	RIOK2	ENSG00000058729.10	12.29	19.68	15.98	ENCSR985KAT
K562	RIOK2	ENSG00000058729.10	17.66	15.37	16.52	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	RIOK2-BGKcLV30-K562	ENCSR262ZBE	RIOK2	K562	Released		ENCSR347NKX	CRISPR	KD% = 50.0,61.0
knockdown followed by RNA-seq	RIOK2-BGHcLV32-HepG2	ENCSR485ZHW	RIOK2	HepG2	Released		ENCSR911CLD	CRISPR	KD% = 87.0,75.7

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RIOK2	ENCAB828CEY	A302-449A	1			Released, ENCODE4	BGHcLV32-33, Released, ENCODE4	BGKcLV30-35, Released, ENCODE4
RIOK2	ENCAB531RFU	A302-450A	1			Released, ENCODE4	BGHcLV32-33, Released, ENCODE4	BGKcLV30-35, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
RIOK2	K562	CRISPR	ENCSR262ZBE	ENCSR347NKX	RIOK2-BGKcLV30-35,RIOK2-BGKcLV30-36	NT-BGKcLV30-1,NT-BGKcLV30-2	50.0,61.0	Released	ENCODE4
RIOK2	HepG2	CRISPR	ENCSR485ZHW	ENCSR911CLD	RIOK2-BGHcLV32-33B,RIOK2-BGHcLV32-34B	NT-BGHcLV32-1B,NT-BGHcLV32-2B	87.0,75.7	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RIOK2	Product_ID: A302-449A Lot_ID: 1 Source: Bethyl Labs Target Name: RIOK2-human
RIOK2	Product_ID: A302-450A Lot_ID: 1 Source: Bethyl Labs Target Name: RIOK2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RIOK2 is not avaliable on ENCORE database.

Proteins bound to RNA

RIOK2 RNA is bound by 1 proteins.

CanvasJS.com

eCLIP assay for RIOK2 is not avaliable on ENCORE database.

1 proteins are bound to RIOK2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr5	96518829	96518860	-	CDS,intron-Distal	4.59169	4.54356	K562	DDX3X
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 1 of 1 entries

eCLIP assay for RIOK2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for RIOK2 is not available on ENCORE database.
61 RBPs can affect the levels of RIOK2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RIOK2 is not available on ENCORE database.

61 RBPs can affect the gene expression of RIOK2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RIOK2	ENSG00000058729.6	1044.81950	469.45710	1.15410	21.65040	20.59400	HepG2	SRSF1
RIOK2	ENSG00000058729.6	1145.93560	549.36650	1.06060	15.82360	14.00990	K562	PRPF8
RIOK2	ENSG00000058729.6	779.20270	383.52760	1.02260	12.63570	11.26050	HepG2	U2AF1
RIOK2	ENSG00000058729.6	809.62210	450.72800	0.84490	11.86870	10.16870	K562	SYNCRIP
RIOK2	ENSG00000058729.6	1913.97230	1099.41360	0.79970	10.99380	9.79260	K562	DDX47
RIOK2	ENSG00000058729.6	1160.97520	776.62070	0.58000	8.60960	6.90400	K562	DKC1
RIOK2	ENSG00000058729.6	1131.80990	640.44640	0.82140	8.85390	6.72180	K562	U2AF1
RIOK2	ENSG00000058729.6	245.63270	422.00090	-0.78070	7.18860	6.35760	HepG2	TAF15
RIOK2	ENSG00000058729.6	943.30840	559.64360	0.75310	7.19770	5.86490	K562	RPS19
RIOK2	ENSG00000058729.6	645.58300	432.01500	0.57940	6.62220	5.84780	HepG2	PTBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 69 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RIOK2 is not available on ENCORE database.

2 RBPs can affect the splicing of RIOK2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	RIOK2	ENSG00000058729.6	chr5	-	96508878	96508993			96506909	96507101	96512819	96513067	-0.09800	0.00010	0.00173	excluded	K562	AQR
MXE	RIOK2	ENSG00000058729.6	chr5	-	96513435	96513552	96514758	96514897	96512819	96512995	96518829	96518964	-0.17500	0.00014	0.00320	2included	K562	U2AF2
MXE	RIOK2	ENSG00000058729.6	chr5	-	96513435	96513485	96514758	96514946	96512819	96512995	96518829	96518964	0.05100	0.00015	0.00177	1included	K562	AQR

Showing 1 to 3 of 3 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RIOK2

General Information

Functions

Localization

Domains (AlphaFold: RIOK2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RIOK2 is not avaliable on ENCORE database.

1 proteins are bound to RIOK2 RNA:

eCLIP assay for RIOK2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RIOK2 is not available on ENCORE database.

61 RBPs can affect the gene expression of RIOK2 :

The Knockdown/knockout RNA-Seq assay for RIOK2 is not available on ENCORE database.

2 RBPs can affect the splicing of RIOK2 :

The Knockdown/knockout RNA-Seq assay for RIOK2 is not avaliable on ENCORE database.