RBM4B

General Information

Gene Name       : RBM4B
Gene ID             : ENSG00000173914.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RBM4B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RBM4BENSG00000173914.1113.0213.1913.11ENCSR000AEF
HepG2RBM4BENSG00000173914.1129.7228.7929.25ENCSR985KAT
K562RBM4BENSG00000173914.1117.1015.0816.09ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
RNA Bind-n-SeqRBNS: RBM4BENCSR905BJKRBM4Bcell-free sampleReleasedENCSR462HQR  






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
RBM4BRibo-STAMP-293TshRNARBM4B-BGRSLV04-43,RBM4B-BGRSLV04-44NT-BGRSLV04-1,NT-BGRSLV04-2,SubmittedENCORE2


  RNA Bind-n-Seqn  
  GeneName    gene_aliases    Status    Project    Note  
RBM4BRBM4BReleasedENCODE3


  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RBM4B is not avaliable on ENCORE database.


  • The binding motifs of RBM4B

    • Trulli

Proteins bound to RNA
  • RBM4B RNA is bound by 6 proteins.  







eCLIP assay for RBM4B is not avaliable on ENCORE database.





6 proteins are bound to RBM4B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116643299666433065-3'-UTR,CDS,intron-Distal,intron-Proximal3.767665.76944HepG2U2AF2
chr116643281166432904-3'-UTR,intron-Distal,intron-Proximal3.422346.20894HepG2PTBP1
chr116643666066436754-3'-UTR,CDS,intron-Distal3.255566.21602K562ZNF622
chr116644409566444193-3'-UTR,CDS,intron-Distal,intron-Proximal5.485299.06713HepG2PRPF8
chr116643281766432895-3'-UTR,intron-Distal,intron-Proximal3.024604.62516K562PTBP1
chr116644411666444204-CDS,intron-Distal,intron-Proximal4.881336.29310K562ZNF622
chr116643308866433151-intron-Distal4.394794.84906K562U2AF1
chr116643368066433724-intron-Distal,intron-Proximal4.182624.73315K562TIA1
chr116643308066433151-intron-Distal4.739207.81397K562U2AF2
chr116643307166433150-intron-Distal3.9638110.82383HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RBM4B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RBM4B is not available on ENCORE database.

  • 52 RBPs can affect the levels of RBM4B.  








The Knockdown/knockout RNA-Seq assay for RBM4B is not available on ENCORE database.





52 RBPs can affect the gene expression of RBM4B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RBM4BENSG00000173914.7517.28730385.262600.425002.467801.52600HepG2ADAR
RBM4BENSG00000173914.7678.65070438.366000.630405.015403.99100HepG2CIRBP
RBM4BENSG00000173914.7516.06550350.894000.556403.080402.35990HepG2CPSF6
RBM4BENSG00000173914.7278.55490395.07600-0.504203.461402.32090HepG2YBX3
RBM4BENSG00000173914.7206.63920458.78290-1.150708.863307.82260HepG2DDX6
RBM4BENSG00000173914.7474.14100375.562900.336201.892801.31580HepG2DKC1
RBM4BENSG00000173914.7285.50170387.95070-0.442402.823902.11590HepG2DNAJC21
RBM4BENSG00000173914.7682.02830487.586100.484102.909502.25420HepG2EIF4A3
RBM4BENSG00000173914.7773.82790558.308400.470904.657203.91440HepG2ETF1
RBM4BENSG00000173914.7530.42730391.667100.437402.732002.08940HepG2HNRNPA1
RBM4BENSG00000173914.7476.35370589.04240-0.306302.394601.76210HepG2HNRNPL
RBM4BENSG00000173914.7362.16590506.41120-0.483702.492301.88970HepG2NCBP2
RBM4BENSG00000173914.7247.31610451.09630-0.867105.898204.85710HepG2PABPC4
RBM4BENSG00000173914.7302.84170385.99760-0.350001.987601.35460HepG2PPIL4
RBM4BENSG00000173914.7329.35250612.09710-0.894109.915508.88360HepG2PUF60
RBM4BENSG00000173914.7489.39700649.77100-0.408904.051703.36380HepG2PUM1
RBM4BENSG00000173914.7461.21930649.29460-0.493404.116403.30560HepG2PUM2
RBM4BENSG00000173914.7598.98960399.850300.583006.678005.79220HepG2PUS1
RBM4BENSG00000173914.7250.77270418.39770-0.738503.223002.46540HepG2RAVER1
RBM4BENSG00000173914.7424.25520583.73200-0.460403.713102.73610HepG2RBM15
RBM4BENSG00000173914.7335.57570235.168300.512802.149901.44460HepG2RPS3A
RBM4BENSG00000173914.7302.05480417.89900-0.468302.320601.34150HepG2RPS5
RBM4BENSG00000173914.7275.24550385.40530-0.485703.528502.81670HepG2SAFB2
RBM4BENSG00000173914.7266.01590375.70210-0.498102.621901.93480HepG2SF3B1
RBM4BENSG00000173914.7314.31380458.39170-0.544404.355203.63910HepG2SF3B4
RBM4BENSG00000173914.7444.95330586.91180-0.399503.338602.57940HepG2SLBP
RBM4BENSG00000173914.7351.05820449.45520-0.356502.460401.84880HepG2SMN1
RBM4BENSG00000173914.7286.30820426.73590-0.575802.980801.98310HepG2SMNDC1
RBM4BENSG00000173914.7279.08530418.03770-0.582902.492901.75220HepG2SNRNP70
RBM4BENSG00000173914.7416.46940527.04380-0.339702.686202.18930HepG2SRFBP1
RBM4BENSG00000173914.7242.59540389.24240-0.682106.246605.47670HepG2SRSF9
RBM4BENSG00000173914.7732.44900457.586200.678609.577508.73580HepG2SSB
RBM4BENSG00000173914.7230.76860391.00920-0.760803.877102.44490HepG2SUB1
RBM4BENSG00000173914.7517.27990687.32100-0.410004.054703.32690HepG2SUCLG1
RBM4BENSG00000173914.7626.41340380.821900.717902.897901.80460HepG2TBRG4
RBM4BENSG00000173914.7288.32200395.16360-0.454802.852102.00370HepG2TIA1
RBM4BENSG00000173914.7273.74620424.27420-0.632205.856605.08980HepG2TRIM56
RBM4BENSG00000173914.7320.63620436.40670-0.444702.365601.78020HepG2U2AF1
RBM4BENSG00000173914.7176.29400439.61500-1.318304.182302.95630HepG2U2AF2
RBM4BENSG00000173914.7372.62190491.57790-0.399702.924102.31180HepG2UTP3
RBM4BENSG00000173914.7322.23810460.15020-0.514002.439301.44560HepG2XRCC6
RBM4BENSG00000173914.7489.76080333.269800.555302.615001.91030HepG2XRN2
RBM4BENSG00000173914.7463.93410559.98310-0.271501.949701.46870HepG2ZNF622
RBM4BENSG00000173914.7463.24330327.609200.499702.837701.95390K562BOP1
RBM4BENSG00000173914.7485.98990348.329800.480403.198102.35320K562CPSF6
RBM4BENSG00000173914.7784.32100654.356800.261302.211501.36730K562EIF4G2
RBM4BENSG00000173914.7477.78210354.442000.430702.328701.54220K562FMR1
RBM4BENSG00000173914.7486.03700375.748300.371202.626501.83770K562MTPAP
RBM4BENSG00000173914.7409.47280295.135900.472302.754101.33820K562PHF6
RBM4BENSG00000173914.7904.31330744.084500.281302.407701.51090K562PUM2
RBM4BENSG00000173914.7235.94860315.90420-0.421002.037301.32080K562RBM22
RBM4BENSG00000173914.7312.71460220.480400.504102.544601.50890K562SAFB
RBM4BENSG00000173914.7224.55220299.05330-0.413402.165801.40940K562SF3B4
RBM4BENSG00000173914.7236.71930322.90350-0.447902.285501.63540K562SRSF1
RBM4BENSG00000173914.7402.90640248.205200.698805.641804.46200K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RBM4B is not available on ENCORE database.





2 RBPs can affect the splicing of RBM4B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERBM4BENSG00000173914.7chr11-6643374266433964664330186643304966436085664361560.300000.008390.07932includedHepG2U2AF2
SERBM4BENSG00000173914.7chr11-6643374266433979664330186643304966436085664363060.579000.000500.00674includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RBM4B is not avaliable on ENCORE database.