PKN3

General Information

Gene Name       : PKN3
Gene ID             : ENSG00000160447.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PKN3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PKN3ENSG00000160447.61.302.091.69ENCSR000AEF
HepG2PKN3ENSG00000160447.616.449.8213.13ENCSR985KAT
K562PKN3ENSG00000160447.620.4813.2516.87ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PKN3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PKN3 RNA is bound by 23 proteins.  







eCLIP assay for PKN3 is not avaliable on ENCORE database.





23 proteins are bound to PKN3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9131482541131482604+CDS,intron-Distal,intron-Proximal4.487555.05356HepG2PRPF8
chr9131465196131465259+CDS,intron-Proximal4.378834.59919HepG2AQR
chr9131476830131476879+CDS,intron-Distal,intron-Proximal3.353345.81258K562AQR
chr9131468995131469010+CDS4.783954.67689HepG2PPIG
chr9131468115131468156+CDS3.614136.82013HepG2PPIG
chr9131469185131469287+CDS4.188124.07395K562SRSF1
chr9131465215131465261+CDS,intron-Proximal3.481514.83899HepG2PRPF8
chr9131469245131469297+CDS4.586589.08097K562DDX24
chr9131477112131477143+CDS,intron-Distal5.515526.36664K562DDX24
chr9131467550131467595+CDS,intron-Proximal3.707604.88100K562AQR
chr9131469249131469299+CDS4.017438.46997HepG2PPIG
chr9131476642131476707+CDS,intron-Distal,intron-Proximal5.509749.40852HepG2PRPF8
chr9131467629131467680+CDS3.842093.34184HepG2GRWD1
chr9131465216131465260+CDS,intron-Proximal5.725108.34710K562AQR
chr9131465841131465993+intron-Distal3.530458.47439K562FUS
chr9131465881131465946+intron-Distal4.8149615.10662K562NONO
chr9131465876131465936+intron-Distal4.474714.53454K562PRPF8
chr9131466213131466287+intron-Distal6.0235917.89843K562NONO
chr9131466230131466314+intron-Distal3.424955.42955K562FUS
chr9131465964131466029+intron-Distal5.451529.47216K562EWSR1
chr9131466492131466565+intron-Distal3.9312211.09092K562NONO
chr9131465767131465828+intron-Distal4.416374.41148HepG2GTF2F1
chr9131467308131467399+intron-Distal3.195663.78108K562FUS
chr9131465755131465812+intron-Distal4.083678.57093K562DROSHA
chr9131465322131465381+intron-Distal4.443993.94684HepG2CSTF2T
chr9131465885131465941+intron-Distal3.797018.56885K562EWSR1
chr9131465741131465839+intron-Distal5.1071614.17100K562EWSR1
chr9131465613131465669+intron-Distal3.305184.00685K562TIA1
chr9131466351131466402+intron-Distal4.034645.89564K562AKAP8L
chr9131465957131466052+intron-Distal3.3558110.81517K562NONO
chr9131465765131465825+intron-Distal3.463034.67419K562FUS
chr9131465610131465694+intron-Distal3.480747.47921K562GEMIN5
chr9131476651131476688+intron-Distal,intron-Proximal5.486078.34710K562AQR
chr9131466345131466392+intron-Distal4.133417.83327K562NONO
chr9131466143131466206+intron-Distal3.350474.40213K562EWSR1
chr9131480711131480770+intron-Distal,intron-Proximal4.367473.59236HepG2AQR
chr9131476644131476651+intron-Distal,intron-Proximal5.060865.69951K562AQR
chr9131465911131465937+intron-Distal3.990143.28818K562LSM11
chr9131465603131465690+intron-Distal3.946196.07730K562CSTF2T
chr9131465611131465692+intron-Distal4.4550510.00464K562EWSR1
chr9131466351131466421+intron-Distal5.061698.86792K562CSTF2T
chr9131466435131466492+intron-Distal3.363137.91387K562NONO
chr9131465594131465662+intron-Distal4.263577.20259K562GTF2F1
chr9131465773131465832+intron-Distal4.111798.45389K562CSTF2T
chr9131465919131465928+intron-Distal5.333715.17878K562DROSHA
chr9131465784131465828+intron-Distal3.750923.52118K562XRCC6
chr9131467326131467403+intron-Distal3.837875.28701K562PRPF8
chr9131465764131465829+intron-Distal4.6334110.56271K562NONO
chr9131465872131465957+intron-Distal3.776497.41671HepG2FAM120A
chr9131467242131467311+intron-Distal3.729835.02933K562CSTF2T
chr9131465767131465834+intron-Distal3.043563.23179HepG2RBFOX2
chr9131465888131465932+intron-Distal3.248463.55868K562DDX52
chr9131465740131465806+intron-Distal4.679756.36164K562DDX24
chr9131465618131465655+intron-Distal3.240143.31097K562SLTM
chr9131465711131465733+intron-Distal4.225933.98553K562NONO
chr9131465590131465677+intron-Distal3.994527.72301HepG2CSTF2T
chr9131466239131466292+intron-Distal3.200273.58403K562EWSR1
chr9131465620131465678+intron-Distal3.044414.78136K562NONO
chr9131466352131466383+intron-Distal3.787465.54974K562EWSR1
chr9131465862131466027+intron-Distal4.8756221.20588K562CSTF2T
chr9131466052131466115+intron-Distal4.4980911.26712K562NONO
chr9131466314131466564+intron-Distal3.6862913.38363K562FUS
chr9131476706131476762+intron-Distal,intron-Proximal4.442174.22101K562PRPF8
chr9131465872131465952+intron-Distal3.183197.64256HepG2CSTF2T
chr9131465783131465828+intron-Distal4.043166.06724K562DDX52
chr9131466606131466680+intron-Distal3.807259.53485K562NONO
chr9131465766131465835+intron-Distal3.516057.07923HepG2CSTF2T
chr9131465327131465369+intron-Distal3.177373.12654K562SLTM
chr9131465755131465803+intron-Distal3.598474.88678K562DHX30
chr9131466138131466213+intron-Distal4.3026013.85198K562NONO
chr9131466748131466808+intron-Distal4.240467.50476K562EWSR1
chr9131465755131465807+intron-Distal4.3987011.04345K562GEMIN5
chr9131465767131465814+intron-Distal3.444863.85148K562GTF2F1
chr9131476230131476318+intron-Proximal4.908235.40008K562SF3B4
chr9131469689131469719+intron-Proximal4.560864.09264K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PKN3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PKN3 is not available on ENCORE database.

  • 94 RBPs can affect the levels of PKN3.  








The Knockdown/knockout RNA-Seq assay for PKN3 is not available on ENCORE database.





94 RBPs can affect the gene expression of PKN3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PKN3ENSG00000160447.6455.72320603.25370-0.404602.725601.33450HepG2ATP5C1
PKN3ENSG00000160447.6446.11800656.26150-0.556805.247304.35190HepG2AUH
PKN3ENSG00000160447.6140.90440297.02750-1.075902.575601.70690HepG2BCLAF1
PKN3ENSG00000160447.6239.17190460.57860-0.945403.640502.96500HepG2BOP1
PKN3ENSG00000160447.6149.85800434.61890-1.5362019.4990017.79730HepG2CALR
PKN3ENSG00000160447.6169.45880272.15670-0.683503.381802.53160HepG2CIRBP
PKN3ENSG00000160447.6282.16860478.38480-0.761609.131708.05830HepG2CKAP4
PKN3ENSG00000160447.6190.45760422.80900-1.150504.636603.76740HepG2CPSF6
PKN3ENSG00000160447.6120.81150220.13060-0.865603.586001.95710HepG2CSTF2T
PKN3ENSG00000160447.6163.08650236.67720-0.537302.065001.46930HepG2DDX21
PKN3ENSG00000160447.6121.52570231.90710-0.932304.399203.23680HepG2DDX24
PKN3ENSG00000160447.6245.32090480.13970-0.968802.315301.42400HepG2DDX59
PKN3ENSG00000160447.6349.41590487.67740-0.481002.909301.87450HepG2DDX5
PKN3ENSG00000160447.6316.64110231.080100.454403.027702.35120HepG2DNAJC2
PKN3ENSG00000160447.6212.69860314.14110-0.562602.993201.84230HepG2EFTUD2
PKN3ENSG00000160447.699.90820218.19840-1.127002.853801.72830HepG2AGO1
PKN3ENSG00000160447.6132.45010273.84790-1.047906.499705.61340HepG2EIF2S1
PKN3ENSG00000160447.6167.38600305.92870-0.870004.277103.16990HepG2EIF3D
PKN3ENSG00000160447.6203.94990302.59250-0.569202.718702.08520HepG2EIF4A3
PKN3ENSG00000160447.6288.37810463.62000-0.685005.976404.83030HepG2EIF4G1
PKN3ENSG00000160447.6302.04210444.10410-0.556103.303502.41780HepG2EIF4G2
PKN3ENSG00000160447.6596.21110753.55270-0.337902.279401.72500HepG2ETF1
PKN3ENSG00000160447.6196.10200423.59040-1.111102.373101.43860HepG2FTO
PKN3ENSG00000160447.6208.08120294.08490-0.499102.537401.78320HepG2FUBP3
PKN3ENSG00000160447.6629.77270305.429001.0439010.885909.60260HepG2FXR1
PKN3ENSG00000160447.6249.32690431.85460-0.792503.803602.73440HepG2HNRNPA2B1
PKN3ENSG00000160447.6559.56070286.984900.963209.322408.10050HepG2HNRNPK
PKN3ENSG00000160447.6196.55650457.32780-1.218305.159704.32800HepG2HNRNPLL
PKN3ENSG00000160447.6408.20650260.078800.650305.909405.05170HepG2HNRNPU
PKN3ENSG00000160447.6146.35820287.90810-0.976106.201205.22790HepG2IGF2BP2
PKN3ENSG00000160447.6217.44080137.704700.658902.777301.58510HepG2KHDRBS1
PKN3ENSG00000160447.6465.80370681.04250-0.548002.467501.68540HepG2LARP4
PKN3ENSG00000160447.6487.57170305.536200.674204.498403.66670HepG2MAGOH
PKN3ENSG00000160447.6500.81470307.225800.704904.508203.72050HepG2MATR3
PKN3ENSG00000160447.6319.92940458.84330-0.520203.658302.26490HepG2NAA15
PKN3ENSG00000160447.6151.78720279.95830-0.883205.320004.32930HepG2PABPC4
PKN3ENSG00000160447.6342.83540231.969600.563503.916003.05540HepG2PPIL4
PKN3ENSG00000160447.6107.19220259.12510-1.273403.268702.39790HepG2PRPF8
PKN3ENSG00000160447.6399.70060258.450500.628905.216204.51380HepG2PTBP1
PKN3ENSG00000160447.6336.75470629.81460-0.903209.152208.33460HepG2RBM22
PKN3ENSG00000160447.6144.24920254.01060-0.816304.092603.28640HepG2RBM25
PKN3ENSG00000160447.6460.53900287.612800.679106.159305.40650HepG2NELFE
PKN3ENSG00000160447.6476.00930267.904500.829209.096308.07710HepG2RECQL
PKN3ENSG00000160447.6151.98080442.07220-1.5404018.8131017.34870HepG2RPLP0
PKN3ENSG00000160447.6206.72230297.73060-0.526302.569001.97490HepG2RPS19
PKN3ENSG00000160447.6119.93150256.30230-1.095602.886302.08550HepG2RRP9
PKN3ENSG00000160447.6319.01000231.612000.461802.850302.19880HepG2SAFB2
PKN3ENSG00000160447.6220.21950452.62100-1.039403.979503.14710HepG2SF3B1
PKN3ENSG00000160447.6397.14950270.099400.556104.637803.84080HepG2SMN1
PKN3ENSG00000160447.6282.67870503.63570-0.833203.088202.26180HepG2SNRNP70
PKN3ENSG00000160447.6268.64830711.32420-1.4048018.3214017.33320HepG2SRFBP1
PKN3ENSG00000160447.6238.80630403.19800-0.755607.017705.99020HepG2SRSF7
PKN3ENSG00000160447.6414.24990617.54840-0.576105.203404.54340HepG2SSB
PKN3ENSG00000160447.6663.84270499.450200.410404.043203.31650HepG2SUCLG1
PKN3ENSG00000160447.6216.07520455.84510-1.0770012.2879010.43070HepG2SUPT6H
PKN3ENSG00000160447.6391.71360254.974100.619305.289104.56080HepG2TRIM56
PKN3ENSG00000160447.6552.45850434.579400.346102.114301.35900HepG2TUFM
PKN3ENSG00000160447.6411.06460577.60240-0.490703.463902.76610HepG2U2AF1
PKN3ENSG00000160447.6293.89420457.77690-0.639306.212905.23350HepG2UPF1
PKN3ENSG00000160447.6325.73120441.96690-0.440302.971302.35460HepG2UTP3
PKN3ENSG00000160447.6357.83690465.99140-0.381002.744602.07460HepG2ZC3H8
PKN3ENSG00000160447.6273.46130503.46820-0.8806012.3607011.41200HepG2ZNF622
PKN3ENSG00000160447.6820.904401549.59620-0.9166013.4717012.31540K562AQR
PKN3ENSG00000160447.6489.94460703.35720-0.521603.716802.70480K562BOP1
PKN3ENSG00000160447.6798.36050572.775200.479004.618703.20040K562CSTF2
PKN3ENSG00000160447.61556.189701294.741900.265302.807001.58690K562DDX21
PKN3ENSG00000160447.61131.969001496.80710-0.403105.679704.79650K562DDX47
PKN3ENSG00000160447.6411.18400286.839800.519403.493702.60520K562EIF3G
PKN3ENSG00000160447.6910.66560734.198200.310702.635201.51980K562EIF4B
PKN3ENSG00000160447.61290.099301018.514500.340903.026001.70040K562EXOSC5
PKN3ENSG00000160447.6982.06240784.307600.324302.211401.45270K562FIP1L1
PKN3ENSG00000160447.6433.91870778.85020-0.843908.581206.42010K562FKBP4
PKN3ENSG00000160447.6573.13330760.91350-0.408902.784501.92780K562FMR1
PKN3ENSG00000160447.638.85490218.83650-2.4937020.2663017.85710K562G3BP2
PKN3ENSG00000160447.6668.59620896.53080-0.423203.501202.83990K562HNRNPC
PKN3ENSG00000160447.61718.111801408.610500.286502.077501.30420K562HNRNPU
PKN3ENSG00000160447.61326.960801063.346900.319402.287601.55980K562HSPD1
PKN3ENSG00000160447.6765.526901194.24760-0.641603.422701.81660K562ILF2
PKN3ENSG00000160447.6353.97490609.67690-0.784403.245902.22610K562KRR1
PKN3ENSG00000160447.61135.79240799.749400.506005.271703.07150K562LSM11
PKN3ENSG00000160447.6742.43390495.427900.583502.610401.79390K562MAGOH
PKN3ENSG00000160447.61986.522801636.439900.279602.786101.87310K562MBNL1
PKN3ENSG00000160447.61437.470701903.48200-0.405104.280202.87980K562MSI2
PKN3ENSG00000160447.61131.65470890.352200.345902.525501.74650K562PPIG
PKN3ENSG00000160447.61227.57140803.873300.610706.552605.06420K562PSIP1
PKN3ENSG00000160447.6865.51920481.378600.846307.806606.73040K562PTBP1
PKN3ENSG00000160447.61582.003202073.04610-0.390003.999002.69530K562PUM1
PKN3ENSG00000160447.61138.38270733.620600.633807.921906.24690K562RCC2
PKN3ENSG00000160447.61314.26590885.532800.569502.412901.40560K562SAFB
PKN3ENSG00000160447.61151.705701600.40230-0.474707.333206.05590K562SF3A3
PKN3ENSG00000160447.6413.22540679.03350-0.716602.834001.84850K562SF3B1
PKN3ENSG00000160447.61134.98740695.433000.706608.596606.51040K562SRFBP1
PKN3ENSG00000160447.6869.13700441.066800.978506.286504.58730K562SRSF4
PKN3ENSG00000160447.6773.43880445.887100.794505.054403.55540K562SRSF5
PKN3ENSG00000160447.677.59680214.80270-1.468906.125003.56420K562TAF15
PKN3ENSG00000160447.6890.60160477.537700.899105.753504.71080K562TARDBP
PKN3ENSG00000160447.6916.25660460.672500.991909.304507.68790K562TIA1
PKN3ENSG00000160447.6819.31530452.358300.856904.135002.75440K562TRA2A
PKN3ENSG00000160447.61178.75700821.604100.520705.313703.89990K562TRIM56
PKN3ENSG00000160447.6108.32260218.97250-1.015406.792805.54080K562U2AF2
PKN3ENSG00000160447.61343.264301719.78020-0.356505.254904.30010K562UPF1
PKN3ENSG00000160447.61047.825801497.94610-0.515602.969801.72190K562UTP3
PKN3ENSG00000160447.61190.368201471.56540-0.305902.643101.78500K562WDR3
PKN3ENSG00000160447.61232.225901530.23140-0.312504.376503.33020K562WDR43
PKN3ENSG00000160447.61400.627301745.76670-0.317802.694001.84410K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PKN3 is not available on ENCORE database.





8 RBPs can affect the splicing of PKN3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPKN3ENSG00000160447.6chr9+131477647131477739131477450131477514131479025131479202-0.116000.000810.01746excludedK562SRSF1
SEPKN3ENSG00000160447.6chr9+131477647131477739131477450131477514131479025131479202-0.139000.000000.00022excludedK562PRPF8
SEPKN3ENSG00000160447.6chr9+131477647131477739131477450131477514131479025131479202-0.176000.000000.00000excludedK562EFTUD2
A3SSPKN3ENSG00000160447.6chr9+1314679581314681581314680121314681581314675811314678220.098000.018460.08902longerK562AQR
A3SSPKN3ENSG00000160447.6chr9+131477076131477144131477105131477144131476884131476943-0.054000.013410.06799shorterK562AQR
A5SSPKN3ENSG00000160447.6chr9+1314824811314825621314824811314825181314826721314831970.391000.000870.05175longerHepG2SRSF1
RIPKN3ENSG00000160447.6chr9+1314769191314771441314769191314769431314770761314771440.150000.002550.01985includedHepG2U2AF2
MXEPKN3ENSG00000160447.6chr9+131477647131477739131479025131479202131477450131477514131480603131480666-0.150000.001130.035642includedK562EFTUD2
MXEPKN3ENSG00000160447.6chr9+1314776471314777391314790251314792021314774501314775141314806031314806660.200000.006220.094821includedHepG2DDX55
MXEPKN3ENSG00000160447.6chr9+1314776471314777391314790251314792021314774501314775141314806031314806660.145000.002870.073981includedK562DDX55
MXEPKN3ENSG00000160447.6chr9+1314776471314777391314790251314792021314774501314775141314806031314806660.131000.000040.002731includedK562DHX30
MXEPKN3ENSG00000160447.6chr9+131477647131477739131479025131479202131477450131477514131480603131480666-0.160000.001230.027112includedK562PRPF8
MXEPKN3ENSG00000160447.6chr9+131477647131477739131479025131479202131477450131477514131480603131480666-0.085000.008240.085562includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PKN3 is not avaliable on ENCORE database.