NFE2

General Information

Gene Name       : NFE2
Gene ID             : ENSG00000123405.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NFE2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NFE2ENSG00000123405.130.000.000.00ENCSR000AEF
HepG2NFE2ENSG00000123405.138.176.517.34ENCSR985KAT
K562NFE2ENSG00000123405.13177.81189.86183.84ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NFE2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NFE2 RNA is bound by 19 proteins.  







eCLIP assay for NFE2 is not avaliable on ENCORE database.





19 proteins are bound to NFE2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr125468907554689141-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.642797.90194K562SF3B4
chr125468614654686196-3'-UTR,CDS,intron-Distal,intron-Proximal4.0687414.45512K562PABPC4
chr125468596854686018-3'-UTR,intron-Distal3.714788.05355K562PABPC4
chr125468903654689088-3'-UTR,5'-UTR,intron-Distal3.038056.62895K562BUD13
chr125468610954686146-3'-UTR,intron-Distal,intron-Proximal3.852757.27995K562PABPC4
chr125469468654694742-5'-UTR,intron-Distal3.8739114.83286K562DDX3X
chr125469403354694111-5'-UTR,intron-Distal,intron-Proximal4.2255125.55961K562AQR
chr125468945154689524-5'-UTR,intron-Distal3.7317717.98372K562UCHL5
chr125469404454694090-5'-UTR,intron-Distal,intron-Proximal3.582344.57279K562PTBP1
chr125469474254694793-5'-UTR,intron-Distal4.0844612.63060K562DDX3X
chr125469454154694586-5'-UTR,intron-Distal4.8121114.93855K562AQR
chr125468661354686704-CDS,intron-Distal4.9432833.19647K562RBM15
chr125468685954686928-CDS,intron-Distal3.771893.72310K562HNRNPK
chr125468693954687074-CDS,intron-Distal3.7306611.21411K562HNRNPK
chr125468631754686386-CDS,intron-Distal3.388457.30599K562DDX6
chr125468879254688933-CDS,intron-Distal,intron-Proximal3.1258013.89198K562SF3B4
chr125468713954687221-CDS,intron-Distal3.6574912.58062K562SF3B4
chr125468662754686731-CDS,intron-Distal3.667297.81993K562METAP2
chr125468676754686813-CDS,intron-Distal4.5931116.28134K562RBM15
chr125468697154687081-CDS,intron-Distal3.6729720.36316K562PCBP1
chr125468686554686944-CDS,intron-Distal4.250216.16083K562ZNF800
chr125468714954687196-CDS,intron-Distal3.5676518.55297K562PRPF8
chr125468712054687152-CDS,intron-Distal4.9037944.20190K562AQR
chr125468716054687186-CDS,intron-Distal3.517836.19583K562RBM15
chr125468892554688959-CDS,intron-Distal3.551029.85344K562BUD13
chr125468632654686360-CDS,intron-Distal3.453187.69141K562RBM15
chr125468711754687206-CDS,intron-Distal3.1258513.50989K562GPKOW
chr125468638354686395-CDS,intron-Distal5.5516227.37373K562RBM15
chr125468887054688921-CDS,intron-Distal,intron-Proximal3.232676.41344HepG2PRPF8
chr125468631154686377-CDS,intron-Distal3.5260914.72895K562UCHL5
chr125468616154686178-CDS,intron-Distal,intron-Proximal3.9745912.74623K562RBM15
chr125468636054686383-CDS,intron-Distal4.8784522.70032K562RBM15
chr125468656054686579-CDS,intron-Distal3.061455.24703K562BUD13
chr125468684454686912-CDS,intron-Distal3.712623.33377K562PUM1
chr125468892254689013-CDS,intron-Distal3.215379.76238K562GRWD1
chr125468648754686525-CDS,intron-Distal3.890199.87361K562RBM15
chr125468711854687201-CDS,intron-Distal3.9290123.65012K562BUD13
chr125468639554686408-CDS,intron-Distal6.2036130.38462K562RBM15
chr125468700654687057-CDS,intron-Distal4.5881313.55882K562RBM15
chr125468634054686362-CDS,intron-Distal4.094973.67707K562METAP2
chr125468616054686180-CDS,intron-Distal,intron-Proximal4.064917.43300K562BUD13
chr125468617854686198-CDS,intron-Distal,intron-Proximal3.9695515.27775K562RBM15
chr125468624154686261-CDS,intron-Distal,intron-Proximal4.419527.70265K562RBM15
chr125468693554686966-CDS,intron-Distal3.015675.48940K562RBM15
chr125468653454686565-CDS,intron-Distal4.5996411.09331K562RBM15
chr125468715254687196-CDS,intron-Distal6.44019400.00000K562AQR
chr125468663954686716-CDS,intron-Distal3.3885311.88863K562GEMIN5
chr125468703054687058-CDS,intron-Distal3.125855.87115K562AQR
chr125468685954686903-CDS,intron-Distal3.8730810.25633K562RBM15
chr125469305254693102-intron-Distal4.685563.92866K562PTBP1
chr125469367054693739-intron-Distal4.0258314.67627K562PTBP1
chr125469356654693645-intron-Distal5.3184610.09004HepG2QKI
chr125469445754694522-intron-Distal4.0608614.59020K562AQR
chr125468887454688919-intron-Distal,intron-Proximal6.17005400.00000K562AQR
chr125468887154688911-intron-Distal,intron-Proximal3.0584310.68422K562BUD13
chr125468886654688874-intron-Distal,intron-Proximal5.3755431.35979K562AQR
chr125468884154688866-intron-Distal,intron-Proximal5.8103046.36597K562AQR
chr125468881654688865-intron-Distal,intron-Proximal4.1190210.24116K562BUD13
chr125469359354693642-intron-Distal4.182155.50753K562QKI
chr125468879154688841-intron-Distal,intron-Proximal5.8104033.94728K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NFE2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NFE2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of NFE2.  








The Knockdown/knockout RNA-Seq assay for NFE2 is not available on ENCORE database.





121 RBPs can affect the gene expression of NFE2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NFE2ENSG00000123405.962.13170115.18160-0.890502.140701.30920HepG2ABCF1
NFE2ENSG00000123405.9115.9701046.255501.326004.811804.05170HepG2ACO1
NFE2ENSG00000123405.9222.45040112.991700.977205.585804.23820HepG2ADAR
NFE2ENSG00000123405.9100.8320046.486901.117004.271603.33310HepG2AKAP8L
NFE2ENSG00000123405.9110.0884036.480601.593406.391005.22040HepG2ASCC1
NFE2ENSG00000123405.922.84790161.81490-2.8242022.3258020.71760HepG2AUH
NFE2ENSG00000123405.99.66150175.77640-4.1853024.6864023.18800HepG2BOP1
NFE2ENSG00000123405.941.65210145.58080-1.8054010.470209.11550HepG2CALR
NFE2ENSG00000123405.972.6054034.659101.066702.376501.65480HepG2CIRBP
NFE2ENSG00000123405.988.7192046.262300.939303.024102.33580HepG2CKAP4
NFE2ENSG00000123405.913.24300161.37980-3.6072017.5561016.00130HepG2CPSF6
NFE2ENSG00000123405.9142.8761069.487201.039804.089902.81110HepG2CSTF2
NFE2ENSG00000123405.967.00410159.60610-1.252208.179607.00820HepG2DAZAP1
NFE2ENSG00000123405.987.0697042.787501.024903.770402.81540HepG2DDX19B
NFE2ENSG00000123405.939.2164082.26360-1.068803.024202.06840HepG2DDX24
NFE2ENSG00000123405.917.1511042.23480-1.300102.168801.60760HepG2DDX3X
NFE2ENSG00000123405.934.36610183.25620-2.4148013.7197011.66390HepG2DDX59
NFE2ENSG00000123405.993.7461036.280301.369504.333703.57520HepG2DDX6
NFE2ENSG00000123405.951.72640109.73780-1.085104.048402.87680HepG2DHX30
NFE2ENSG00000123405.920.69840113.77670-2.4586013.7673012.29490HepG2DNAJC21
NFE2ENSG00000123405.9163.52500112.773100.536002.247101.64680HepG2DNAJC2
NFE2ENSG00000123405.9218.9547079.200501.467008.733807.20260HepG2EEF2
NFE2ENSG00000123405.9119.3070064.303800.891602.745301.84620HepG2EIF3D
NFE2ENSG00000123405.980.4333037.527501.099702.512901.85570HepG2EIF4B
NFE2ENSG00000123405.947.96210157.43280-1.7148011.305609.84130HepG2EIF4G1
NFE2ENSG00000123405.920.20610150.81570-2.8999019.5084017.50460HepG2EIF4G2
NFE2ENSG00000123405.998.64930185.77440-0.913205.105404.33440HepG2ETF1
NFE2ENSG00000123405.935.5040080.11790-1.174103.515802.25120HepG2FASTKD2
NFE2ENSG00000123405.9277.85770116.314501.256207.625806.41380HepG2FIP1L1
NFE2ENSG00000123405.924.51100161.64070-2.7213010.930208.95320HepG2FTO
NFE2ENSG00000123405.9291.1352084.359501.7870014.7096012.41540HepG2FUS
NFE2ENSG00000123405.9269.1282038.888602.7908026.8444024.96570HepG2FXR1
NFE2ENSG00000123405.967.6325036.075100.906602.016301.44490HepG2G3BP1
NFE2ENSG00000123405.9133.3324057.257301.219405.431904.17260HepG2GEMIN5
NFE2ENSG00000123405.9315.64160114.866701.4582013.1520011.91450HepG2HNRNPA1
NFE2ENSG00000123405.925.64420127.76830-2.3168011.7330010.39430HepG2HNRNPC
NFE2ENSG00000123405.960.00570138.01490-1.201705.954904.95590HepG2HNRNPF
NFE2ENSG00000123405.996.6457036.528801.403604.591403.71080HepG2HNRNPK
NFE2ENSG00000123405.978.73050145.39900-0.885004.351503.51960HepG2HNRNPL
NFE2ENSG00000123405.932.06000174.59770-2.4452014.6503013.35830HepG2HNRNPLL
NFE2ENSG00000123405.9185.2183080.276101.206107.357005.92100HepG2HNRNPM
NFE2ENSG00000123405.947.34000135.90740-1.521508.046906.87180HepG2IGF2BP1
NFE2ENSG00000123405.966.21470129.64820-0.969404.636503.70720HepG2ILF2
NFE2ENSG00000123405.9111.7732036.883201.599405.956004.42950HepG2KHSRP
NFE2ENSG00000123405.9111.4314039.120001.510105.440104.58030HepG2MATR3
NFE2ENSG00000123405.9157.5497067.307201.226902.703701.66350HepG2METAP2
NFE2ENSG00000123405.998.89220178.02170-0.848102.698701.74320HepG2MTPAP
NFE2ENSG00000123405.987.1760040.041501.122302.186001.62110HepG2NCBP2
NFE2ENSG00000123405.9205.57290101.686201.015403.242602.05140HepG2NONO
NFE2ENSG00000123405.9179.7199054.046401.733404.921902.37520HepG2NUFIP2
NFE2ENSG00000123405.9157.4203048.086401.710807.748505.19260HepG2PA2G4
NFE2ENSG00000123405.9150.4975047.996501.6486010.684009.61710HepG2PCBP1
NFE2ENSG00000123405.9132.0697079.841300.726002.323201.36890HepG2PCBP2
NFE2ENSG00000123405.9139.1227053.175701.387407.308505.37750HepG2PKM
NFE2ENSG00000123405.9168.48310113.205600.573602.396601.70630HepG2PPIL4
NFE2ENSG00000123405.9252.21250113.756001.148604.382802.15190HepG2PSIP1
NFE2ENSG00000123405.9166.9789048.844501.7733012.0878011.10440HepG2PTBP1
NFE2ENSG00000123405.952.64160151.06710-1.520908.491607.52390HepG2PUF60
NFE2ENSG00000123405.986.08440160.24320-0.896404.193803.37740HepG2PUM2
NFE2ENSG00000123405.9197.4035047.116702.0667019.0086017.65420HepG2PUS1
NFE2ENSG00000123405.915.1266052.88650-1.805804.143103.40010HepG2QKI
NFE2ENSG00000123405.9102.16970155.27530-0.603901.954201.49900HepG2RBM22
NFE2ENSG00000123405.9189.0636097.709500.952202.293801.32970HepG2RCC2
NFE2ENSG00000123405.9190.8952054.354101.8122013.0294012.01400HepG2NELFE
NFE2ENSG00000123405.9195.4792050.632801.9488015.5915014.32230HepG2RECQL
NFE2ENSG00000123405.911.65500148.64420-3.6728024.6637023.05050HepG2RPLP0
NFE2ENSG00000123405.918.6812075.72860-2.019303.945302.81880HepG2RPS10
NFE2ENSG00000123405.9139.4486062.560301.156305.241604.42550HepG2RPS19
NFE2ENSG00000123405.940.1070084.38120-1.073102.989102.17550HepG2RRP9
NFE2ENSG00000123405.943.76450113.03080-1.368906.304905.39200HepG2SAFB2
NFE2ENSG00000123405.9281.9222052.572502.422809.872507.09300HepG2SF1
NFE2ENSG00000123405.928.91950172.82920-2.5792015.2775013.76310HepG2SF3B1
NFE2ENSG00000123405.9143.8577051.007001.495803.407901.76040HepG2SFPQ
NFE2ENSG00000123405.9220.63570131.812700.743103.566802.85180HepG2SMN1
NFE2ENSG00000123405.981.18190192.29850-1.244105.313604.21970HepG2SNRNP70
NFE2ENSG00000123405.919.52230175.38170-3.1673027.7719026.61540HepG2SRFBP1
NFE2ENSG00000123405.933.98620135.58780-1.9962012.0841010.80830HepG2SRSF7
NFE2ENSG00000123405.919.43020152.27970-2.9703022.4172021.26480HepG2SSB
NFE2ENSG00000123405.919.9766077.72540-1.960106.290804.52150HepG2STAU1
NFE2ENSG00000123405.935.5538078.57390-1.144003.266802.25070HepG2SUPT6H
NFE2ENSG00000123405.914.17370110.15240-2.9582014.6735013.32950HepG2SUPV3L1
NFE2ENSG00000123405.990.30570170.12380-0.913703.856303.01590HepG2TARDBP
NFE2ENSG00000123405.979.0901031.146901.344303.273602.11490HepG2TBRG4
NFE2ENSG00000123405.933.70690123.32860-1.8714010.051209.20150HepG2TIAL1
NFE2ENSG00000123405.9145.1275077.395900.906902.869501.37420HepG2TRA2A
NFE2ENSG00000123405.976.67390124.43250-0.698602.742702.18000HepG2TRIM56
NFE2ENSG00000123405.9223.61410147.568600.599502.556201.71920HepG2TUFM
NFE2ENSG00000123405.949.2575099.52130-1.014702.760502.13210HepG2U2AF1
NFE2ENSG00000123405.973.06090156.18750-1.096104.066903.04200HepG2UBE2L3
NFE2ENSG00000123405.922.6928065.05740-1.519504.574203.59500HepG2UCHL5
NFE2ENSG00000123405.926.6328059.48730-1.159402.862002.15300HepG2UPF1
NFE2ENSG00000123405.9235.90560108.433501.121305.254804.26450HepG2XRN2
NFE2ENSG00000123405.922.11870127.99650-2.5328016.5464015.13500HepG2ZC3H8
NFE2ENSG00000123405.96529.994604586.725200.509506.974405.89780K562AKAP8L
NFE2ENSG00000123405.95427.497004091.911300.407402.818201.75140K562CCAR1
NFE2ENSG00000123405.97164.523505268.296500.443406.969805.08530K562CCDC124
NFE2ENSG00000123405.911938.722809040.768600.401003.446401.80970K562CKAP4
NFE2ENSG00000123405.911651.493207602.162500.615904.010002.68900K562CNOT7
NFE2ENSG00000123405.916651.6228011148.515500.5787013.7973011.73120K562CELF1
NFE2ENSG00000123405.93704.642304443.64540-0.262403.804402.22620K562DDX27
NFE2ENSG00000123405.96645.088404581.062900.536506.664404.49710K562DHX30
NFE2ENSG00000123405.96899.851004378.463800.656006.263904.31940K562EEF2
NFE2ENSG00000123405.94859.147003693.943400.395408.391006.25460K562EIF2S1
NFE2ENSG00000123405.93303.054106458.71610-0.9674034.0029032.02620K562EIF2S2
NFE2ENSG00000123405.93093.357102400.395500.365805.088604.02300K562EIF3G
NFE2ENSG00000123405.93996.226603164.084200.336804.782203.19360K562EIF4B
NFE2ENSG00000123405.911426.178909066.455600.333606.491905.07510K562EIF4G2
NFE2ENSG00000123405.93757.504403066.915600.292903.443601.97290K562EWSR1
NFE2ENSG00000123405.97910.297006622.975500.256202.567501.35140K562EXOSC5
NFE2ENSG00000123405.99422.777807022.815000.424005.210204.02220K562FIP1L1
NFE2ENSG00000123405.93106.927003653.87970-0.233902.848302.23620K562FXR1
NFE2ENSG00000123405.91328.686902285.72840-0.782704.692003.71610K562G3BP2
NFE2ENSG00000123405.98274.712306279.746000.397907.443905.63180K562GLRX3
NFE2ENSG00000123405.910193.189708606.221000.244102.138301.46820K562GRSF1
NFE2ENSG00000123405.95598.710904362.402300.359903.805001.38530K562GRWD1
NFE2ENSG00000123405.910192.910806823.322000.578903.416901.40540K562HNRNPA0
NFE2ENSG00000123405.97096.004805761.974100.300303.445002.24130K562HNRNPA1
NFE2ENSG00000123405.95545.584104482.075300.307103.259802.01210K562HNRNPF
NFE2ENSG00000123405.94569.482105776.43200-0.338102.596301.69790K562HNRNPM
NFE2ENSG00000123405.98087.960506381.074300.341905.644204.35630K562HNRNPU
NFE2ENSG00000123405.95754.062309521.35320-0.7266013.3192011.61760K562HSPD1
NFE2ENSG00000123405.95308.154304131.156600.361602.919301.39460K562KHDRBS1
NFE2ENSG00000123405.96533.647405090.726000.359903.263301.64360K562LIN28B
NFE2ENSG00000123405.95142.246203422.165700.5874010.532508.62540K562MATR3
NFE2ENSG00000123405.912118.702809663.837200.326503.265802.03390K562MSI2
NFE2ENSG00000123405.97916.322606602.275500.261805.124504.04750K562MTPAP
NFE2ENSG00000123405.910370.146307336.049400.4993013.0789011.62320K562NSUN2
NFE2ENSG00000123405.96388.367004900.147700.382504.415702.56070K562PHF6
NFE2ENSG00000123405.92642.047604116.01800-0.639605.860604.76710K562PRPF8
NFE2ENSG00000123405.95724.831504500.013700.347202.378401.54720K562PSIP1
NFE2ENSG00000123405.96244.374609892.10460-0.6637013.2559011.45420K562PUF60
NFE2ENSG00000123405.96234.732004432.210700.492209.245408.18390K562RBM15
NFE2ENSG00000123405.95217.048004105.952500.345404.594403.31410K562RCC2
NFE2ENSG00000123405.910190.376206925.576100.557103.623901.81880K562SBDS
NFE2ENSG00000123405.91993.956803890.17130-0.964204.147102.59470K562SF1
NFE2ENSG00000123405.98510.188707238.320100.233403.162002.29110K562SF3A3
NFE2ENSG00000123405.94805.666103892.304900.304002.886001.83180K562SRFBP1
NFE2ENSG00000123405.98890.176907415.771100.261506.264304.92210K562SRPK2
NFE2ENSG00000123405.95187.336403963.380900.388202.572301.56350K562SRSF4
NFE2ENSG00000123405.95786.645603305.626700.8077014.3939012.53090K562TARDBP
NFE2ENSG00000123405.93870.890003129.937400.306402.838401.72720K562TRA2A
NFE2ENSG00000123405.96815.623904598.486600.567606.646305.03350K562TRIM56
NFE2ENSG00000123405.91634.532202214.09970-0.437802.800001.69940K562U2AF1
NFE2ENSG00000123405.95250.941604216.915700.316302.419601.47380K562UCHL5
NFE2ENSG00000123405.95674.936407778.54270-0.4549012.0661010.69740K562UPF1
NFE2ENSG00000123405.910169.280407680.997200.404805.098803.86930K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NFE2 is not available on ENCORE database.





4 RBPs can affect the splicing of NFE2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENFE2ENSG00000123405.9chr12-546939305469406054688918546890885469458454694799-0.061000.000480.01151excludedK562SRSF1
SENFE2ENSG00000123405.9chr12-5468932754689394546889185468908854694584546947990.193000.000000.00000includedK562AQR
SENFE2ENSG00000123405.9chr12-546939305469406054688918546890885469458454694799-0.055000.001350.01569excludedK562AQR
SENFE2ENSG00000123405.9chr12-546939305469406054688918546890885469458454694799-0.105000.000130.03168excludedK562LARP4
SENFE2ENSG00000123405.9chr12-546939305469406054688918546890885469458454694799-0.052000.001960.08314excludedK562EFTUD2
MXENFE2ENSG00000123405.9chr12-5468932754689394546939305469406054688918546890885469458454694799-0.190000.000000.000002includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NFE2 is not avaliable on ENCORE database.