MCCC1

General Information

Gene Name       : MCCC1
Gene ID             : ENSG00000078070.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MCCC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MCCC1ENSG00000078070.1233.0031.5032.25ENCSR000AEF
HepG2MCCC1ENSG00000078070.1216.2221.8019.01ENCSR985KAT
K562MCCC1ENSG00000078070.1216.4415.4715.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MCCC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MCCC1 RNA is bound by 8 proteins.  







eCLIP assay for MCCC1 is not avaliable on ENCORE database.





8 proteins are bound to MCCC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3182775097182775204-3'-UTR,CDS,intron-Distal,intron-Proximal3.663254.70460K562DDX24
chr3182759453182759518-3'-UTR,CDS,intron-Distal3.372824.85828HepG2BCLAF1
chr3182743518182743616-3'-UTR,CDS,intron-Distal,intron-Proximal3.742863.55754HepG2U2AF2
chr3182769949182770012-3'-UTR,CDS,intron-Distal4.228305.65086HepG2BCLAF1
chr3182790154182790200-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.720394.17155HepG2BCLAF1
chr3182812356182812393-5'-UTR,CDS,intron-Distal4.127123.49905HepG2PPIG
chr3182817217182817303-5'-UTR,CDS,intron-Distal,intron-Proximal4.181664.52089HepG2NCBP2
chr3182817139182817229-5'-UTR,CDS,intron-Distal3.966165.52342HepG2PPIG
chr3182736278182736314-intron-Distal4.465794.80399K562EXOSC5
chr3182746717182746858-intron-Distal,intron-Proximal4.436225.46313K562KHSRP
chr3182736327182736386-intron-Distal5.083027.38793K562EXOSC5
chr3182754188182754304-intron-Distal4.196754.21977HepG2HNRNPL
chr3182735485182735542-intron-Distal4.196273.30687K562EXOSC5
chr3182735848182735895-intron-Distal4.165575.80877K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MCCC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MCCC1 is not available on ENCORE database.

  • 92 RBPs can affect the levels of MCCC1.  








The Knockdown/knockout RNA-Seq assay for MCCC1 is not available on ENCORE database.





92 RBPs can affect the gene expression of MCCC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MCCC1ENSG00000078070.7342.70770463.28850-0.434903.439502.77420HepG2ACO1
MCCC1ENSG00000078070.7456.68450675.23250-0.564204.001703.06360HepG2ASCC1
MCCC1ENSG00000078070.7611.54200732.70230-0.260801.946701.35260HepG2AUH
MCCC1ENSG00000078070.7359.79300459.41960-0.352601.992601.32940HepG2CALR
MCCC1ENSG00000078070.7311.56280463.14400-0.571905.512404.63330HepG2CKAP4
MCCC1ENSG00000078070.7235.06400335.80590-0.514602.501701.84240HepG2CPSF6
MCCC1ENSG00000078070.7303.34990446.89610-0.559003.523202.28160HepG2CPSF7
MCCC1ENSG00000078070.7442.85050652.55280-0.559305.995705.11850HepG2CELF1
MCCC1ENSG00000078070.7577.67100428.455300.431004.354503.33740HepG2DDX19B
MCCC1ENSG00000078070.7316.22700452.66300-0.517503.304902.56810HepG2DDX21
MCCC1ENSG00000078070.7603.56680781.74930-0.373202.110201.55660HepG2DDX3X
MCCC1ENSG00000078070.7343.48130671.47550-0.967108.889807.84790HepG2DDX6
MCCC1ENSG00000078070.7385.51750645.56850-0.743806.140805.27650HepG2EIF2S1
MCCC1ENSG00000078070.7225.39320385.12910-0.772903.309702.32720HepG2EIF3D
MCCC1ENSG00000078070.7383.06490694.59500-0.858606.159405.16320HepG2EIF4B
MCCC1ENSG00000078070.7629.71630841.30410-0.417904.752704.00350HepG2ETF1
MCCC1ENSG00000078070.7301.03640452.67670-0.588504.389403.34160HepG2EWSR1
MCCC1ENSG00000078070.7442.98820719.75880-0.700205.922104.93580HepG2FXR1
MCCC1ENSG00000078070.7412.88070667.73020-0.693505.462204.54140HepG2G3BP1
MCCC1ENSG00000078070.7453.90990708.81800-0.643005.207903.97360HepG2G3BP2
MCCC1ENSG00000078070.7257.09830409.77570-0.672504.449603.58510HepG2HNRNPC
MCCC1ENSG00000078070.7317.68380676.02440-1.0895012.8304011.43620HepG2HNRNPK
MCCC1ENSG00000078070.7283.19230407.06740-0.523504.182403.44970HepG2HNRNPU
MCCC1ENSG00000078070.7373.78380678.75040-0.860708.186607.08930HepG2IGF2BP2
MCCC1ENSG00000078070.7371.56520636.90860-0.777502.596201.64550HepG2IGF2BP3
MCCC1ENSG00000078070.7510.93310415.807800.297102.216401.55260HepG2ILF2
MCCC1ENSG00000078070.7499.97210673.18060-0.429102.273601.52770HepG2LARP4
MCCC1ENSG00000078070.7511.64290720.00970-0.492903.252002.54110HepG2MAGOH
MCCC1ENSG00000078070.7966.53710724.054400.416602.520301.91550HepG2MATR3
MCCC1ENSG00000078070.7400.51700741.12210-0.887808.641807.55520HepG2NCBP2
MCCC1ENSG00000078070.7509.06510695.80200-0.450804.108303.17880HepG2NOL12
MCCC1ENSG00000078070.7445.25860322.111400.467002.517901.80290HepG2NSUN2
MCCC1ENSG00000078070.7401.42230660.07340-0.717505.927104.88320HepG2PABPC4
MCCC1ENSG00000078070.7486.86820384.614600.340002.273101.56450HepG2PRPF4
MCCC1ENSG00000078070.7143.87810273.42790-0.926305.601004.49520HepG2PRPF8
MCCC1ENSG00000078070.7485.52340680.94930-0.488004.515103.85330HepG2PTBP1
MCCC1ENSG00000078070.7392.29460664.19120-0.759708.078907.13210HepG2PUF60
MCCC1ENSG00000078070.7554.64600705.05340-0.346203.472102.82250HepG2PUM1
MCCC1ENSG00000078070.7476.43410704.54760-0.564405.563904.62660HepG2PUM2
MCCC1ENSG00000078070.7599.33020737.52060-0.299302.093301.53820HepG2QKI
MCCC1ENSG00000078070.7414.68890703.16130-0.761809.928309.08410HepG2RBM22
MCCC1ENSG00000078070.7452.01540669.33390-0.566405.091404.20230HepG2RBM25
MCCC1ENSG00000078070.7384.41180527.72290-0.457102.353601.44710HepG2RBM27
MCCC1ENSG00000078070.7595.38970757.84510-0.348102.919702.36590HepG2NELFE
MCCC1ENSG00000078070.7354.37080474.08090-0.419902.551601.89160HepG2RPLP0
MCCC1ENSG00000078070.7252.23170374.72700-0.571103.515402.83120HepG2RPS19
MCCC1ENSG00000078070.7454.78010362.518400.327002.129401.55150HepG2SAFB2
MCCC1ENSG00000078070.7343.19390562.85770-0.713704.800803.89740HepG2SF3A3
MCCC1ENSG00000078070.7432.10660708.98620-0.714409.446308.45380HepG2SF3B4
MCCC1ENSG00000078070.7199.90340490.24860-1.294203.964802.17290HepG2SFPQ
MCCC1ENSG00000078070.7567.21300794.17130-0.485606.043505.38200HepG2SRFBP1
MCCC1ENSG00000078070.71212.60980740.015800.7124013.2635012.39390HepG2SRSF1
MCCC1ENSG00000078070.7426.20970655.77420-0.621607.430806.47260HepG2SRSF5
MCCC1ENSG00000078070.7408.41340602.03170-0.559806.315205.54120HepG2SRSF9
MCCC1ENSG00000078070.71046.25720689.487600.601509.682908.83770HepG2SSB
MCCC1ENSG00000078070.7270.30420428.96570-0.666303.031201.76920HepG2SUB1
MCCC1ENSG00000078070.7583.88530745.81120-0.353103.384502.71020HepG2SUCLG1
MCCC1ENSG00000078070.7169.49430352.93510-1.058207.370906.35190HepG2SUPV3L1
MCCC1ENSG00000078070.7435.38840611.19170-0.489304.020503.01850HepG2TIA1
MCCC1ENSG00000078070.7474.61570648.86240-0.451203.434102.44790HepG2TUFM
MCCC1ENSG00000078070.7137.08390468.69740-1.7736022.3826020.53370HepG2U2AF1
MCCC1ENSG00000078070.7107.46240525.49240-2.2898011.037808.95980HepG2U2AF2
MCCC1ENSG00000078070.7257.27420504.79580-0.972407.231005.58630HepG2XRCC6
MCCC1ENSG00000078070.7396.10380548.99040-0.470904.685004.02140HepG2ZNF622
MCCC1ENSG00000078070.7581.23460927.48780-0.6742010.412109.40240K562AGGF1
MCCC1ENSG00000078070.7388.67460933.30660-1.2638019.5678018.17600K562AQR
MCCC1ENSG00000078070.7815.972901012.57040-0.311402.859401.93240K562ATP5C1
MCCC1ENSG00000078070.7285.26220469.23630-0.718005.252804.03920K562BOP1
MCCC1ENSG00000078070.7562.15580744.74020-0.405802.833901.53690K562CIRBP
MCCC1ENSG00000078070.7347.78300498.94040-0.520703.927702.99400K562CPSF6
MCCC1ENSG00000078070.71092.787101429.39830-0.387404.392103.15510K562CELF1
MCCC1ENSG00000078070.7263.16540469.13420-0.834007.053405.54230K562EFTUD2
MCCC1ENSG00000078070.7307.00260419.73330-0.451202.588001.34280K562EWSR1
MCCC1ENSG00000078070.7322.05640507.64530-0.656504.944303.79310K562FMR1
MCCC1ENSG00000078070.7269.82100430.26890-0.673204.405503.22760K562FTO
MCCC1ENSG00000078070.7224.07480476.37130-1.0881011.611109.95890K562GPKOW
MCCC1ENSG00000078070.7569.89160905.75250-0.668407.215605.98370K562GRSF1
MCCC1ENSG00000078070.7324.78690536.64400-0.724506.358505.48930K562HNRNPC
MCCC1ENSG00000078070.7412.57830694.02640-0.750306.713004.72260K562HNRNPK
MCCC1ENSG00000078070.7390.82490739.01530-0.9191014.0561012.10230K562HNRNPU
MCCC1ENSG00000078070.7905.148901147.40230-0.342102.967702.01670K562MBNL1
MCCC1ENSG00000078070.7311.03010464.98900-0.580104.193403.10050K562METAP2
MCCC1ENSG00000078070.7483.61850641.90680-0.408503.630502.71370K562MTPAP
MCCC1ENSG00000078070.7359.40280480.14770-0.417902.624701.42670K562NCBP2
MCCC1ENSG00000078070.7442.70400669.89030-0.597602.231601.36270K562PABPN1
MCCC1ENSG00000078070.7355.82580649.78280-0.868809.517607.67020K562PCBP2
MCCC1ENSG00000078070.7335.04970456.52360-0.446302.369001.67290K562PRPF8
MCCC1ENSG00000078070.7337.60460481.16750-0.511203.110602.14530K562PSIP1
MCCC1ENSG00000078070.7618.372001268.14120-1.0362017.9779015.83890K562PUF60
MCCC1ENSG00000078070.71036.133701321.61340-0.351104.077302.90500K562PUM2
MCCC1ENSG00000078070.7634.21850957.20090-0.593805.246704.52970K562PUS1
MCCC1ENSG00000078070.7715.09150932.55820-0.383103.603602.94060K562RBM15
MCCC1ENSG00000078070.7346.03350680.37100-0.9754012.3257010.35860K562RBM22
MCCC1ENSG00000078070.7476.63050824.16210-0.790103.277001.57230K562RBM39
MCCC1ENSG00000078070.7321.83410439.05080-0.448102.863401.85520K562RCC2
MCCC1ENSG00000078070.7560.10500703.76650-0.329402.450301.67990K562SF3A3
MCCC1ENSG00000078070.7303.75890453.02400-0.576703.237302.18350K562SF3B1
MCCC1ENSG00000078070.7358.74300494.50300-0.463003.386602.43860K562SF3B4
MCCC1ENSG00000078070.7356.83840747.04820-1.065905.555603.41970K562SFPQ
MCCC1ENSG00000078070.7896.71550695.550400.366402.876502.15830K562SRSF1
MCCC1ENSG00000078070.7268.01130441.91220-0.721504.873803.49370K562SUPV3L1
MCCC1ENSG00000078070.7526.16540356.662200.560904.632603.56350K562SYNCRIP
MCCC1ENSG00000078070.7363.84810703.95770-0.9522011.236009.65460K562TARDBP
MCCC1ENSG00000078070.7538.32390679.04270-0.335002.316901.57510K562TIA1
MCCC1ENSG00000078070.7338.48480462.79680-0.451302.362001.50260K562TIAL1
MCCC1ENSG00000078070.7186.44010460.96860-1.3060013.1413010.56000K562U2AF1
MCCC1ENSG00000078070.7152.59670476.09470-1.6415025.7215023.28520K562U2AF2
MCCC1ENSG00000078070.7565.78480756.22990-0.418604.272503.39820K562UPF1
MCCC1ENSG00000078070.7652.65870970.39230-0.572202.688101.42170K562UTP18
MCCC1ENSG00000078070.7478.39050699.44360-0.548003.705302.30470K562UTP3
MCCC1ENSG00000078070.7342.32640563.12090-0.718103.283901.52490K562XRCC6
MCCC1ENSG00000078070.7755.589301051.44680-0.476704.523403.37710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MCCC1 is not available on ENCORE database.





7 RBPs can affect the splicing of MCCC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMCCC1ENSG00000078070.7chr3-1827468801827469771827435421827435921827517781827518650.217000.000660.01910includedHepG2HNRNPK
SEMCCC1ENSG00000078070.7chr3-182743542182743592182740256182740342182751778182751865-0.235000.001520.02005excludedHepG2U2AF2
SEMCCC1ENSG00000078070.7chr3-182755005182755222182751778182751865182756835182756948-0.095000.003210.03231excludedK562AQR
SEMCCC1ENSG00000078070.7chr3-182743542182743592182740256182740342182751778182751865-0.132000.000050.00098excludedK562AQR
SEMCCC1ENSG00000078070.7chr3-182743542182743592182740256182740342182751778182751865-0.099000.004120.05371excludedK562PUS1
SEMCCC1ENSG00000078070.7chr3-182743542182743592182740256182740342182751778182751865-0.166000.001640.02980excludedK562U2AF2
SEMCCC1ENSG00000078070.7chr3-182804480182804576182790153182790275182810196182810333-0.069000.004920.09198excludedK562AGGF1
SEMCCC1ENSG00000078070.7chr3-182810196182810333182804480182804576182812346182812393-0.482000.000000.00013excludedK562HNRNPC
A3SSMCCC1ENSG00000078070.7chr3-1827889971827891811827889971827891451827901531827902750.136000.000220.00175longerK562AQR
A3SSMCCC1ENSG00000078070.7chr3-1827550051827552511827550051827552221827568131827569230.207000.000000.00000longerK562AQR
MXEMCCC1ENSG00000078070.7chr3-182790153182790275182804480182804576182788997182789145182812346182812393-0.299000.000410.011592includedHepG2FTO
MXEMCCC1ENSG00000078070.7chr3-1827517781827518651827550051827552511827435421827435921827568131827569230.123000.010700.066861includedK562AQR
MXEMCCC1ENSG00000078070.7chr3-1827517781827518651827550051827552481827435421827435921827568131827569230.122000.009620.061381includedK562AQR
MXEMCCC1ENSG00000078070.7chr3-1827901531827902751828044801828045761827889971827891451828123461828123930.362000.000070.002241includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MCCC1 is not avaliable on ENCORE database.