LRRC40

General Information

Gene Name       : LRRC40
Gene ID             : ENSG00000066557.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LRRC40)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LRRC40ENSG00000066557.530.2923.2826.79ENCSR000AEF
HepG2LRRC40ENSG00000066557.59.3324.0316.68ENCSR985KAT
K562LRRC40ENSG00000066557.516.8219.1718.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LRRC40 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LRRC40 RNA is bound by 15 proteins.  







eCLIP assay for LRRC40 is not avaliable on ENCORE database.





15 proteins are bound to LRRC40 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr17061133770611518-3'-UTR,CDS,intron-Distal3.539994.09228K562CPSF6
chr17067118370671234-5'-UTR,CDS,intron-Distal3.660225.65306K562ZNF622
chr17067109170671177-CDS,intron-Distal3.112105.13820HepG2NCBP2
chr17061408170614171-CDS,intron-Distal,intron-Proximal4.594399.63457K562KHSRP
chr17065048270650575-CDS,intron-Distal3.725084.49347K562UCHL5
chr17061417670614247-CDS,intron-Distal3.277704.06531HepG2GRWD1
chr17067103670671097-CDS,intron-Distal4.854225.68502HepG2PRPF8
chr17061820570618226-CDS,intron-Distal4.512874.78529HepG2BCLAF1
chr17062137170621397-CDS,intron-Distal,intron-Proximal4.665304.78529HepG2BCLAF1
chr17064160770641667-CDS,intron-Distal,intron-Proximal3.007554.23325HepG2BCLAF1
chr17063915670639230-CDS,intron-Distal,intron-Proximal4.525915.24155K562BUD13
chr17067110670671183-CDS,intron-Distal4.7381711.98007K562ZNF622
chr17063912270639288-CDS,intron-Distal,intron-Proximal3.331155.75231K562AQR
chr17067109270671203-CDS,intron-Distal3.383453.79741HepG2GRWD1
chr17067107770671137-CDS,intron-Distal3.528924.40383K562UCHL5
chr17064151470641607-CDS,intron-Distal4.480337.53358HepG2BCLAF1
chr17063916770639247-CDS,intron-Distal,intron-Proximal4.089945.16342K562SF3B4
chr17063916670639292-CDS,intron-Distal,intron-Proximal5.606566.03057K562EFTUD2
chr17061413670614212-CDS,intron-Distal,intron-Proximal5.461735.68502HepG2PRPF8
chr17063504370635106-intron-Distal5.4442510.01029K562EXOSC5
chr17061387770613999-intron-Distal4.993367.49883HepG2KHSRP
chr17063504870635088-intron-Distal4.041673.29197K562HNRNPM
chr17063478770634811-intron-Distal3.360933.15041K562EXOSC5
chr17061391570613943-intron-Distal3.7333311.36345K562KHSRP
chr17061161470611705-intron-Distal4.044283.42844K562KHSRP
chr17063733670637453-intron-Distal3.780733.04956HepG2HNRNPL
chr17061387270613915-intron-Distal4.385769.40001K562KHSRP
chr17063581770635859-intron-Distal4.699738.80920K562EXOSC5
chr17064031370640393-intron-Distal3.329653.90146K562KHSRP
chr17063941770639549-intron-Distal,intron-Proximal3.480338.32500K562KHSRP
chr17063484870634916-intron-Distal5.5445911.33292K562EXOSC5
chr17063485670634919-intron-Distal4.008643.07980HepG2HNRNPM
chr17063520670635249-intron-Distal3.649729.14720K562EXOSC5
chr17063560370635646-intron-Distal6.2203415.32150K562EXOSC5
chr17063460870634682-intron-Distal3.555457.98944K562EXOSC5
chr17063553070635568-intron-Distal4.591983.89085K562EXOSC5
chr17061394870614038-intron-Distal3.614096.80241K562KHSRP
chr17063604970636076-intron-Distal3.457253.72952K562EXOSC5
chr17063483570634945-intron-Distal4.968966.10662K562HNRNPM
chr17063533970635363-intron-Distal4.373093.30696K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LRRC40 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LRRC40 is not available on ENCORE database.

  • 91 RBPs can affect the levels of LRRC40.  








The Knockdown/knockout RNA-Seq assay for LRRC40 is not available on ENCORE database.





91 RBPs can affect the gene expression of LRRC40 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LRRC40ENSG00000066557.5401.79590655.69700-0.706604.653903.64890HepG2ASCC1
LRRC40ENSG00000066557.5396.64700632.63730-0.673503.985102.86060HepG2BCCIP
LRRC40ENSG00000066557.5285.32740549.77400-0.946207.579406.17920HepG2BCLAF1
LRRC40ENSG00000066557.5518.15090390.863900.406602.667201.60850HepG2CSTF2
LRRC40ENSG00000066557.5650.44830439.712400.564802.756801.40670HepG2CSTF2T
LRRC40ENSG00000066557.5688.23360867.36950-0.333703.065302.39530HepG2CELF1
LRRC40ENSG00000066557.5442.96850932.68530-1.0742026.9478025.08080HepG2DAZAP1
LRRC40ENSG00000066557.5516.71350759.15090-0.555002.844802.21080HepG2DDX3X
LRRC40ENSG00000066557.5216.70420651.96860-1.5891016.0522014.72640HepG2DDX6
LRRC40ENSG00000066557.5343.89830503.57030-0.550203.494502.24120HepG2EFTUD2
LRRC40ENSG00000066557.5390.86420626.90980-0.681604.498103.75280HepG2EIF2S1
LRRC40ENSG00000066557.5641.32140881.41250-0.458803.650702.72250HepG2EIF4G2
LRRC40ENSG00000066557.5833.961001070.02540-0.359603.573102.90370HepG2ETF1
LRRC40ENSG00000066557.5463.01750682.35170-0.559403.695102.96430HepG2GPKOW
LRRC40ENSG00000066557.5436.65050685.67640-0.651005.719204.75000HepG2HNRNPC
LRRC40ENSG00000066557.5501.25320761.57560-0.603404.490403.60110HepG2HNRNPF
LRRC40ENSG00000066557.5429.22870656.30060-0.612604.492103.62030HepG2HNRNPK
LRRC40ENSG00000066557.5495.67270849.62010-0.7774014.6077013.16830HepG2HNRNPL
LRRC40ENSG00000066557.5458.97470681.14280-0.569506.915505.99490HepG2HNRNPU
LRRC40ENSG00000066557.5522.16190749.94710-0.522303.237602.45910HepG2IGF2BP1
LRRC40ENSG00000066557.51171.62620703.055500.736706.324605.40160HepG2MATR3
LRRC40ENSG00000066557.5433.92810719.64670-0.729805.352504.48620HepG2NCBP2
LRRC40ENSG00000066557.5509.70790924.84620-0.8595014.1749012.51020HepG2NOL12
LRRC40ENSG00000066557.5494.18460674.21050-0.448104.352703.31970HepG2PARN
LRRC40ENSG00000066557.5472.90490607.52440-0.361402.740502.00610HepG2PPIL4
LRRC40ENSG00000066557.51042.22370660.720500.657502.452501.30200HepG2PRPF6
LRRC40ENSG00000066557.5749.91320582.249000.365003.318502.73020HepG2PTBP1
LRRC40ENSG00000066557.5642.69160882.83270-0.458003.998703.29680HepG2PUF60
LRRC40ENSG00000066557.5718.03470937.14950-0.384204.972804.22490HepG2PUM1
LRRC40ENSG00000066557.5673.91600936.47510-0.474704.855303.98000HepG2PUM2
LRRC40ENSG00000066557.5862.91300630.652500.452304.099403.35920HepG2QKI
LRRC40ENSG00000066557.5315.99400769.38040-1.283804.458802.31800HepG2RBM39
LRRC40ENSG00000066557.5844.56930648.011600.382103.420302.83220HepG2NELFE
LRRC40ENSG00000066557.5296.19820477.07420-0.687704.673203.89750HepG2RPS19
LRRC40ENSG00000066557.5621.66070474.819600.388602.261001.54320HepG2RRP9
LRRC40ENSG00000066557.51025.08070659.574800.636003.835102.02700HepG2RTF1
LRRC40ENSG00000066557.5438.21090606.58580-0.469104.672803.87240HepG2SAFB2
LRRC40ENSG00000066557.5612.15920846.46540-0.467506.054305.07950HepG2SLBP
LRRC40ENSG00000066557.5580.62330707.37810-0.284902.509901.89290HepG2SMN1
LRRC40ENSG00000066557.51795.99700632.771201.5049062.2167060.63900HepG2SRSF1
LRRC40ENSG00000066557.5513.46600748.17960-0.543103.925003.11780HepG2SRSF7
LRRC40ENSG00000066557.51097.30160877.089100.323103.656603.08490HepG2SSB
LRRC40ENSG00000066557.5819.73300991.32190-0.274202.753002.13240HepG2SUCLG1
LRRC40ENSG00000066557.5354.39680500.88680-0.499103.277302.25980HepG2SUPT6H
LRRC40ENSG00000066557.5435.66990634.65080-0.542703.991503.14030HepG2TARDBP
LRRC40ENSG00000066557.5405.39350661.84460-0.707208.182707.40640HepG2TIAL1
LRRC40ENSG00000066557.5388.04840667.77490-0.7831011.6437010.60340HepG2TRIM56
LRRC40ENSG00000066557.5677.88580862.46350-0.347402.565201.72650HepG2TUFM
LRRC40ENSG00000066557.5379.26340634.44850-0.742306.303605.37190HepG2U2AF1
LRRC40ENSG00000066557.5239.42640880.01670-1.877907.041205.39300HepG2U2AF2
LRRC40ENSG00000066557.5216.69280365.82910-0.755504.738303.73990HepG2UCHL5
LRRC40ENSG00000066557.5496.74960633.08290-0.349902.892802.18060HepG2UPF1
LRRC40ENSG00000066557.5804.22130611.215000.395803.942903.24650HepG2UTP3
LRRC40ENSG00000066557.5866.90400596.245500.539902.955501.65070HepG2XRCC5
LRRC40ENSG00000066557.5424.91360609.55640-0.520602.742102.02010HepG2XRN2
LRRC40ENSG00000066557.5653.41140494.233900.402703.870303.09880HepG2ZC3H8
LRRC40ENSG00000066557.51109.383901462.46800-0.398603.100802.48650K562AQR
LRRC40ENSG00000066557.5625.60710881.07690-0.494006.105404.66040K562BCLAF1
LRRC40ENSG00000066557.5296.59560425.63930-0.521103.140802.00040K562CCAR1
LRRC40ENSG00000066557.51284.026301578.14450-0.297602.739901.57070K562CCDC124
LRRC40ENSG00000066557.5763.325201132.65620-0.569303.879102.35180K562CIRBP
LRRC40ENSG00000066557.5779.048701132.46260-0.539703.425401.79660K562CKAP4
LRRC40ENSG00000066557.51029.900801465.38040-0.508807.274805.45110K562CPEB4
LRRC40ENSG00000066557.5515.83480748.22420-0.536605.067203.59730K562DDX3X
LRRC40ENSG00000066557.5599.65560758.60900-0.339202.678701.40280K562DDX6
LRRC40ENSG00000066557.5430.59020695.81510-0.692406.046104.65290K562EFTUD2
LRRC40ENSG00000066557.5655.09740821.89700-0.327202.919501.67000K562EIF2S1
LRRC40ENSG00000066557.5746.830601116.53110-0.580205.695704.71870K562EIF2S2
LRRC40ENSG00000066557.5503.70590781.72350-0.634106.275705.04820K562EIF4A3
LRRC40ENSG00000066557.5603.92340839.56140-0.475303.657002.66990K562FMR1
LRRC40ENSG00000066557.5484.17560711.59510-0.555504.121802.98780K562FTO
LRRC40ENSG00000066557.51350.97370914.618100.562703.309802.52330K562G3BP2
LRRC40ENSG00000066557.5467.23190787.83430-0.753808.392707.00230K562GPKOW
LRRC40ENSG00000066557.51040.090201488.04620-0.516702.762002.00690K562GRSF1
LRRC40ENSG00000066557.5330.37690932.25140-1.4966020.3314018.79570K562HNRNPC
LRRC40ENSG00000066557.5589.42860832.35110-0.497904.302202.84170K562HNRNPF
LRRC40ENSG00000066557.5714.860201370.33970-0.9388016.2348013.60030K562HNRNPL
LRRC40ENSG00000066557.5732.897501056.28300-0.527303.749702.48640K562IGF2BP2
LRRC40ENSG00000066557.5839.355201074.60260-0.356402.570901.43520K562IGF2BP3
LRRC40ENSG00000066557.5828.334601110.65530-0.423103.125902.23160K562MAGOH
LRRC40ENSG00000066557.51350.564701633.61680-0.274502.304401.48700K562MBNL1
LRRC40ENSG00000066557.5439.04820769.01060-0.808609.607907.90690K562METAP2
LRRC40ENSG00000066557.5776.96860985.95510-0.343703.567902.65590K562MTPAP
LRRC40ENSG00000066557.5891.289601095.42130-0.297503.475702.64890K562NSUN2
LRRC40ENSG00000066557.5829.25690581.672500.511503.222002.35350K562POLR2G
LRRC40ENSG00000066557.5786.175801140.78400-0.537105.193704.01350K562PPIG
LRRC40ENSG00000066557.5445.94460835.81910-0.906308.645106.84920K562PSIP1
LRRC40ENSG00000066557.51572.123602052.46690-0.384603.714902.77260K562PUF60
LRRC40ENSG00000066557.52695.887802183.078100.304303.261802.09920K562PUM1
LRRC40ENSG00000066557.5713.135501034.95830-0.537303.800602.80460K562RBM22
LRRC40ENSG00000066557.5675.35060868.04550-0.362102.619501.33290K562RBM25
LRRC40ENSG00000066557.5634.981001333.91470-1.070906.127403.60110K562RBM39
LRRC40ENSG00000066557.5528.54410762.37480-0.528504.808103.49910K562RCC2
LRRC40ENSG00000066557.5486.88480991.65090-1.026304.614902.93650K562SF1
LRRC40ENSG00000066557.5810.946101080.99560-0.414704.583603.55780K562SF3A3
LRRC40ENSG00000066557.5638.99080951.53980-0.574506.868405.48480K562SF3B4
LRRC40ENSG00000066557.5505.72980722.73180-0.515103.963302.66660K562SRFBP1
LRRC40ENSG00000066557.5762.27500998.81300-0.389902.286901.34840K562SRSF5
LRRC40ENSG00000066557.5427.16880655.70260-0.618204.308403.01640K562SUPV3L1
LRRC40ENSG00000066557.5768.08700583.417800.396603.270802.37850K562SYNCRIP
LRRC40ENSG00000066557.5582.992401070.64210-0.876909.087707.70570K562TARDBP
LRRC40ENSG00000066557.5716.242301032.72070-0.527904.393503.32440K562TIA1
LRRC40ENSG00000066557.5508.86950803.94270-0.659805.590504.21630K562TIAL1
LRRC40ENSG00000066557.5787.171301013.09500-0.364002.435701.42520K562TRA2A
LRRC40ENSG00000066557.5598.85280853.85990-0.511804.183002.96940K562TRIM56
LRRC40ENSG00000066557.5371.62090551.31360-0.569003.271901.33540K562TRNAU1AP
LRRC40ENSG00000066557.5551.95580887.12200-0.684605.873804.15100K562U2AF1
LRRC40ENSG00000066557.5462.35190916.02080-0.9864016.8147014.79050K562U2AF2
LRRC40ENSG00000066557.5902.970401161.50340-0.363204.280603.40570K562UPF1
LRRC40ENSG00000066557.51345.865601647.57250-0.291802.299701.52510K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LRRC40 is not available on ENCORE database.





17 RBPs can affect the splicing of LRRC40 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.143000.000000.00009excludedK562AKAP8L
SELRRC40ENSG00000066557.5chr1-7065294770653021706504677065059770654774706549560.070000.000400.08417includedK562WDR43
SELRRC40ENSG00000066557.5chr1-706445337064467670641492706416657064676870646892-0.052000.009450.08728excludedHepG2U2AF2
SELRRC40ENSG00000066557.5chr1-706547747065495670650467706505977067107270671303-0.093000.002580.03105excludedHepG2U2AF2
SELRRC40ENSG00000066557.5chr1-706391477063919370625012706251217064149270641696-0.101000.000040.00071excludedK562AQR
SELRRC40ENSG00000066557.5chr1-706467687064689270644533706446767065046770650597-0.095000.000050.00100excludedK562AQR
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.249000.000000.00000excludedK562AQR
SELRRC40ENSG00000066557.5chr1-7065294770653021706504677065059770654774706549560.087000.002240.07260includedK562FXR1
SELRRC40ENSG00000066557.5chr1-706393047063939270639147706391937064149270641665-0.158000.002690.03840excludedK562PUS1
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.214000.000000.00000excludedK562PUS1
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.185000.000060.00219excludedK562U2AF1
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.145000.000000.00000excludedK562HNRNPL
SELRRC40ENSG00000066557.5chr1-7065294770653021706504677065059770654774706549560.063000.000730.01988includedHepG2SRSF1
SELRRC40ENSG00000066557.5chr1-7065294770653021706504677065059770654774706549560.187000.000570.08664includedK562FXR2
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.161000.000000.00000excludedK562UTP18
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.180000.000230.00584excludedK562U2AF2
SELRRC40ENSG00000066557.5chr1-706467687064689270644533706446767065046770650597-0.266000.000000.00000excludedK562U2AF2
SELRRC40ENSG00000066557.5chr1-706393047063939270639147706391937064149270641665-0.144000.003570.07079excludedK562RBM15
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.107000.000100.00423excludedK562RBM15
SELRRC40ENSG00000066557.5chr1-706393047063939270639147706391937064149270641665-0.164000.002310.05252excludedK562AGGF1
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.135000.000000.00021excludedK562AGGF1
SELRRC40ENSG00000066557.5chr1-706547747065495670650467706505977067107270671303-0.235000.001470.05798excludedHepG2HNRNPU
SELRRC40ENSG00000066557.5chr1-706529477065302170650467706505977065477470654956-0.097000.002060.03480excludedK562HNRNPC
A3SSLRRC40ENSG00000066557.5chr1-7062501270625158706250127062512170639147706391930.061000.000160.00135longerK562AQR
A3SSLRRC40ENSG00000066557.5chr1-7062137170621513706213717062147970625012706251350.110000.000170.00143longerK562AQR
A5SSLRRC40ENSG00000066557.5chr1-706710597067130370671072706713037065477470654956-0.116000.000270.06665shorterK562FXR2
RILRRC40ENSG00000066557.5chr1-7063914770639345706391477063919370639304706393450.087000.005090.02923includedK562AQR
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654956706504677065059770671072706713030.211000.000240.007521includedHepG2FTO
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654948706504677065059770671072706713030.081000.000150.007731includedK562RBM15
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654948706504677065059770671072706713030.180000.000000.000001includedK562PUS1
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654948706504677065059770671072706713030.113000.000000.000231includedK562AGGF1
MXELRRC40ENSG00000066557.5chr1-70625012706251807064149270641696706213717062147970644533706446760.060000.000190.002091includedK562AQR
MXELRRC40ENSG00000066557.5chr1-7065046770650597706547747065495670644533706446767067107270671303-0.122000.000010.000212includedK562AQR
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654948706504677065059770671072706713030.129000.000000.000021includedK562UTP18
MXELRRC40ENSG00000066557.5chr1-7065046770650597706547747065495670644533706446767067107270671303-0.092000.000150.001662includedHepG2U2AF2
MXELRRC40ENSG00000066557.5chr1-7063914770639193706393047063939270625012706251217064149270641665-0.101000.009050.049872includedHepG2U2AF2
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654956706504677065059770671072706713030.141000.007810.092291includedK562SF3B4
MXELRRC40ENSG00000066557.5chr1-70652947706530217065477470654948706504677065059770671072706713030.110000.000000.000301includedK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LRRC40 is not avaliable on ENCORE database.