LIAS

General Information

Gene Name       : LIAS
Gene ID             : ENSG00000121897.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LIAS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LIASENSG00000121897.1425.5221.9823.75ENCSR000AEF
HepG2LIASENSG00000121897.148.7217.5613.14ENCSR985KAT
K562LIASENSG00000121897.1432.4833.4232.95ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LIAS is not avaliable on ENCORE database.



Proteins bound to RNA
  • LIAS RNA is bound by 4 proteins.  







eCLIP assay for LIAS is not avaliable on ENCORE database.





4 proteins are bound to LIAS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr43946522139465267+CDS,intron-Distal,intron-Proximal3.127144.48980K562PRPF8
chr43946907639469177+CDS,intron-Distal,intron-Proximal4.651575.47569HepG2U2AF2
chr43946519439465265+CDS,intron-Distal,intron-Proximal4.6467111.09609HepG2PRPF8
chr43946683939466987+CDS,intron-Distal,intron-Proximal3.887026.82477K562EFTUD2
chr43946649939466656+intron-Distal,intron-Proximal3.077244.18967K562KHSRP
chr43946543139465548+intron-Distal4.499785.25174K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LIAS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LIAS is not available on ENCORE database.

  • 71 RBPs can affect the levels of LIAS.  








The Knockdown/knockout RNA-Seq assay for LIAS is not available on ENCORE database.





71 RBPs can affect the gene expression of LIAS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LIASENSG00000121897.9105.84570176.34050-0.736403.776703.08710HepG2ACO1
LIASENSG00000121897.9133.85010308.47650-1.204507.822506.97740HepG2AKAP1
LIASENSG00000121897.9107.24650177.19870-0.724403.584902.72460HepG2AKAP8L
LIASENSG00000121897.9208.15480319.08930-0.616304.205803.39190HepG2AUH
LIASENSG00000121897.982.76400154.96200-0.904802.998802.06130HepG2BCLAF1
LIASENSG00000121897.9154.75530272.16700-0.814503.553502.68030HepG2CNOT7
LIASENSG00000121897.9215.01260295.16540-0.457102.440201.82880HepG2CELF1
LIASENSG00000121897.9148.48940295.51400-0.992906.316005.40900HepG2DDX3X
LIASENSG00000121897.9142.14090253.81300-0.836404.110003.36860HepG2DDX6
LIASENSG00000121897.9100.02920152.96920-0.612802.404601.74370HepG2DNAJC21
LIASENSG00000121897.9133.47720244.03590-0.870504.565403.81440HepG2EIF2S1
LIASENSG00000121897.9274.76470366.33730-0.415002.074801.53900HepG2ETF1
LIASENSG00000121897.994.44490175.80230-0.896403.137002.32310HepG2FIP1L1
LIASENSG00000121897.9194.64420272.06590-0.483101.986801.39650HepG2FXR1
LIASENSG00000121897.9117.30410252.41130-1.105506.962205.92650HepG2G3BP1
LIASENSG00000121897.9120.65100251.93370-1.062205.791104.16970HepG2GRSF1
LIASENSG00000121897.998.38010154.43450-0.650602.176201.59730HepG2HNRNPA1
LIASENSG00000121897.988.12160171.77430-0.962904.224603.38070HepG2HNRNPC
LIASENSG00000121897.9218.41560289.10330-0.404502.146201.54280HepG2HNRNPL
LIASENSG00000121897.9119.20870170.63900-0.517502.118301.57950HepG2HNRNPU
LIASENSG00000121897.9169.94470256.58130-0.594402.627901.96760HepG2IGF2BP2
LIASENSG00000121897.9180.87690273.69320-0.597602.484501.88340HepG2MATR3
LIASENSG00000121897.9103.44420280.14790-1.4373010.937809.71940HepG2NCBP2
LIASENSG00000121897.9201.70970314.70770-0.641704.258303.31250HepG2NOL12
LIASENSG00000121897.9165.84260249.52490-0.589402.554001.85720HepG2PABPC4
LIASENSG00000121897.9167.16730250.37480-0.582803.206002.56180HepG2PCBP1
LIASENSG00000121897.9163.86310254.77280-0.636703.661103.05070HepG2PTBP1
LIASENSG00000121897.9147.00010300.41630-1.031107.816406.88190HepG2PUF60
LIASENSG00000121897.9211.52580318.90550-0.592304.355703.64800HepG2PUM1
LIASENSG00000121897.9179.90990318.67230-0.824805.966004.99440HepG2PUM2
LIASENSG00000121897.9169.80730275.91010-0.700304.086103.34690HepG2QKI
LIASENSG00000121897.9229.14590306.19430-0.418201.958601.50310HepG2RBM22
LIASENSG00000121897.9162.98950250.41180-0.619503.092602.38390HepG2RBM25
LIASENSG00000121897.9175.39720283.53170-0.692904.197603.55650HepG2NELFE
LIASENSG00000121897.978.40740130.05340-0.730002.411701.83300HepG2RPS19
LIASENSG00000121897.9149.99200273.22650-0.865204.556103.53140HepG2RPS3A
LIASENSG00000121897.9182.59700265.23860-0.538602.748602.15870HepG2SF3B4
LIASENSG00000121897.9184.09830345.84260-0.909608.406407.66320HepG2SRFBP1
LIASENSG00000121897.9160.33330296.61770-0.887507.104606.16550HepG2SRSF5
LIASENSG00000121897.9117.26230175.35020-0.580502.810402.10860HepG2SRSF7
LIASENSG00000121897.9145.42350225.24230-0.631203.537602.93060HepG2SRSF9
LIASENSG00000121897.9120.23780167.28860-0.476401.848601.36970HepG2TRIM56
LIASENSG00000121897.9172.57370293.49460-0.766104.764103.58480HepG2TUFM
LIASENSG00000121897.9198.34880130.421000.604802.694402.10370HepG2UTP3
LIASENSG00000121897.984.77940147.19930-0.796003.528402.78390HepG2ZC3H8
LIASENSG00000121897.981.44330148.56990-0.867304.250603.61160HepG2ZNF622
LIASENSG00000121897.9598.94800782.02930-0.384803.424902.80610K562AGGF1
LIASENSG00000121897.9528.96150937.47160-0.825609.108008.14260K562AQR
LIASENSG00000121897.9157.44720238.21930-0.597402.924201.83630K562CCAR1
LIASENSG00000121897.9410.09790643.68110-0.650403.037801.91730K562CNOT7
LIASENSG00000121897.9269.57360372.95770-0.468302.610901.84840K562CPSF6
LIASENSG00000121897.91090.39980768.583100.504507.076106.10130K562DDX47
LIASENSG00000121897.9250.45710466.17730-0.896304.724703.51600K562EFTUD2
LIASENSG00000121897.9500.64660707.36910-0.498705.000104.07450K562EIF2S2
LIASENSG00000121897.9307.61270499.27240-0.698702.774301.73680K562EIF3D
LIASENSG00000121897.9267.18000379.48360-0.506202.646801.81060K562FMR1
LIASENSG00000121897.9836.49320599.761100.479902.795802.08340K562G3BP2
LIASENSG00000121897.9262.11710356.07950-0.442002.188901.48130K562GPKOW
LIASENSG00000121897.9253.84150473.89430-0.900608.286407.30320K562HNRNPC
LIASENSG00000121897.9288.54040423.11010-0.552303.485402.19390K562HNRNPF
LIASENSG00000121897.9574.70110760.67300-0.404503.712202.67610K562HNRNPU
LIASENSG00000121897.91014.27830667.394700.603705.992604.83480K562HSPD1
LIASENSG00000121897.9490.80570744.61910-0.601404.202802.82510K562IGF2BP2
LIASENSG00000121897.9589.82700781.12550-0.405303.306002.28630K562MATR3
LIASENSG00000121897.9467.50470605.53420-0.373203.235902.43360K562NSUN2
LIASENSG00000121897.9391.97540618.38980-0.657803.600602.17510K562PABPC1
LIASENSG00000121897.9330.55440648.26470-0.971704.887503.46670K562PABPN1
LIASENSG00000121897.9467.79350696.42710-0.574104.902603.58890K562PCBP2
LIASENSG00000121897.9285.06310452.34300-0.666104.295803.25820K562PCBP3
LIASENSG00000121897.9253.94520346.96630-0.450302.315701.58350K562POLR2G
LIASENSG00000121897.9943.479701269.81510-0.428603.643902.71010K562PUF60
LIASENSG00000121897.91032.717501323.37230-0.357803.549302.46290K562PUM2
LIASENSG00000121897.9552.15140729.22830-0.401302.834101.98320K562RBM22
LIASENSG00000121897.9369.35500586.33290-0.666703.499101.73590K562SBDS
LIASENSG00000121897.9412.75660597.54960-0.533804.957503.89300K562SF3A3
LIASENSG00000121897.9237.23010338.65630-0.513502.251401.38450K562SF3B1
LIASENSG00000121897.9480.75820623.97850-0.376202.718801.87120K562SF3B4
LIASENSG00000121897.9238.72860367.38640-0.621903.591402.37890K562SRFBP1
LIASENSG00000121897.9386.95830527.76930-0.447703.394102.08970K562SRSF7
LIASENSG00000121897.9478.56050754.48220-0.656806.128705.04310K562TARDBP
LIASENSG00000121897.9286.76620408.67060-0.511102.643101.73130K562TIAL1
LIASENSG00000121897.9288.77440434.04280-0.587903.936202.76500K562TRIM56
LIASENSG00000121897.9865.774201110.77870-0.359502.888401.56520K562WRN
LIASENSG00000121897.9745.635001056.06950-0.502204.880103.68440K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LIAS is not available on ENCORE database.





9 RBPs can affect the splicing of LIAS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELIASENSG00000121897.9chr4+394638153946390939462409394625823946514439465225-0.198000.000220.00596excludedK562SF3B4
SELIASENSG00000121897.9chr4+394747193947483139472855394729263947868239479241-0.113000.000330.03444excludedK562XRCC6
SELIASENSG00000121897.9chr4+394638153946390939462409394625823946514439465225-0.087000.007660.06578excludedK562AQR
SELIASENSG00000121897.9chr4+394691373946926639466904394669623947163839471784-0.115000.007940.08815excludedK562PUS1
SELIASENSG00000121897.9chr4+3946913739469266394669043946696239471638394717840.363000.002010.07587includedHepG2SFPQ
SELIASENSG00000121897.9chr4+394638153946390939462409394625823946514439465225-0.185000.000280.00794excludedK562U2AF1
SELIASENSG00000121897.9chr4+394638153946390939462409394625823946514439465225-0.192000.000130.00360excludedK562U2AF2
SELIASENSG00000121897.9chr4+394747193947483139472855394729263947868239479241-0.091000.004250.06124excludedK562HNRNPC
MXELIASENSG00000121897.9chr4+39465095394652253946913739469266394624093946258239471638394717840.110000.000220.002411includedK562AQR
MXELIASENSG00000121897.9chr4+39462409394625823946514439465225394606193946078239466665394668220.208000.001750.083491includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LIAS is not avaliable on ENCORE database.