ITCH

General Information

Gene Name : ITCH
Gene ID : ENSG00000078747.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ITCH)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ITCH	ENSG00000078747.14	20.72	18.82	19.77	ENCSR000AEF
HepG2	ITCH	ENSG00000078747.14	35.56	48.63	42.09	ENCSR985KAT
K562	ITCH	ENSG00000078747.14	19.88	22.31	21.09	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ITCH is not avaliable on ENCORE database.

Proteins bound to RNA

ITCH RNA is bound by 38 proteins.

CanvasJS.com

eCLIP assay for ITCH is not avaliable on ENCORE database.

38 proteins are bound to ITCH RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr20	33069045	33069123	+	intron-Distal,intron-Proximal	5.96473	31.37436	HepG2	QKI
chr20	33026238	33026334	+	CDS,intron-Proximal	4.29192	27.47628	HepG2	U2AF2
chr20	32951129	32951212	+	5'-UTR,intron-Proximal	5.06265	24.61945	HepG2	NCBP2
chr20	32951101	32951129	+	5'-UTR	5.53903	24.46822	HepG2	NCBP2
chr20	33080318	33080402	+	CDS	4.24560	24.33458	HepG2	BCLAF1
chr20	32996477	32996548	+	CDS,intron-Distal	4.07699	23.92775	HepG2	BCLAF1
chr20	33000341	33000413	+	5'-UTR,CDS	4.07194	22.80217	HepG2	BCLAF1
chr20	33027923	33028032	+	CDS,intron-Proximal	3.43178	22.74562	HepG2	U2AF2
chr20	33095499	33095553	+	CDS,intron-Proximal	3.55023	20.64547	HepG2	BCLAF1
chr20	33068876	33068983	+	CDS	3.23385	19.99289	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 181 entries

eCLIP assay for ITCH is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ITCH is not available on ENCORE database.
83 RBPs can affect the levels of ITCH.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ITCH is not available on ENCORE database.

83 RBPs can affect the gene expression of ITCH :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ITCH	ENSG00000078747.8	2031.96340	3452.07400	-0.76460	35.02030	32.94810	HepG2	HNRNPL
ITCH	ENSG00000078747.8	1429.07790	2811.17010	-0.97610	22.26690	20.73700	HepG2	HNRNPA1
ITCH	ENSG00000078747.8	1600.51970	2770.50520	-0.79160	21.70220	19.78600	HepG2	PPIL4
ITCH	ENSG00000078747.8	2097.81060	3045.25510	-0.53770	13.77800	12.65610	HepG2	TRIM56
ITCH	ENSG00000078747.8	873.16170	1623.78300	-0.89500	13.67030	11.60500	HepG2	CSTF2
ITCH	ENSG00000078747.8	6718.40460	5043.81020	0.41350	12.18490	11.33190	HepG2	SRFBP1
ITCH	ENSG00000078747.8	2192.18000	3106.22360	-0.50280	12.37940	11.17370	HepG2	HNRNPU
ITCH	ENSG00000078747.8	1422.93690	2532.43810	-0.83170	11.30200	9.85560	HepG2	XRN2
ITCH	ENSG00000078747.8	3052.19690	1971.78820	0.63020	11.40000	9.79250	K562	CPSF6
ITCH	ENSG00000078747.8	734.92390	1200.66390	-0.70820	11.26620	8.95280	K562	CSTF2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 91 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ITCH is not available on ENCORE database.

12 RBPs can affect the splicing of ITCH :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	ITCH	ENSG00000078747.8	chr20	+	33012285	33012331			33001547	33001685	33026278	33026436	-0.09200	0.00000	0.00000	excluded	K562	PUS1
SE	ITCH	ENSG00000078747.8	chr20	+	33012285	33012331			33001547	33001685	33026278	33026436	-0.09200	0.00000	0.00001	excluded	K562	UTP18
SE	ITCH	ENSG00000078747.8	chr20	+	33012285	33012331			33001547	33001685	33026278	33026436	-0.07800	0.00000	0.00021	excluded	K562	AGGF1
SE	ITCH	ENSG00000078747.8	chr20	+	33004922	33005045			33001547	33001685	33012285	33012331	0.13100	0.00000	0.00004	included	HepG2	HNRNPC
A3SS	ITCH	ENSG00000078747.8	chr20	+	33077047	33077191			33077070	33077191	33068870	33069011	0.15900	0.00000	0.00000	longer	K562	AQR
SE	ITCH	ENSG00000078747.8	chr20	+	33012285	33012331			33001547	33001685	33026278	33026436	-0.07400	0.00001	0.00048	excluded	K562	AKAP8L
MXE	ITCH	ENSG00000078747.8	chr20	+	32996456	32996598	33000320	33000445	32981596	32981687	33001547	33001685	0.18100	0.00007	0.01464	1included	K562	LARP4
SE	ITCH	ENSG00000078747.8	chr20	+	33004922	33005045			33001547	33001685	33012285	33012331	0.10400	0.00016	0.00409	included	K562	HNRNPC
SE	ITCH	ENSG00000078747.8	chr20	+	32981596	32981687			32957199	32957276	32996456	32996598	-0.09600	0.00037	0.00742	excluded	K562	PUS1
SE	ITCH	ENSG00000078747.8	chr20	+	33012285	33012331			33001547	33001685	33026278	33026436	-0.05400	0.00111	0.01336	excluded	K562	AQR

Showing 1 to 10 of 20 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ITCH

General Information

Functions

Localization

Domains (AlphaFold: ITCH)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ITCH is not avaliable on ENCORE database.

38 proteins are bound to ITCH RNA:

eCLIP assay for ITCH is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ITCH is not available on ENCORE database.

83 RBPs can affect the gene expression of ITCH :

The Knockdown/knockout RNA-Seq assay for ITCH is not available on ENCORE database.

12 RBPs can affect the splicing of ITCH :

The Knockdown/knockout RNA-Seq assay for ITCH is not avaliable on ENCORE database.