IK

General Information

Gene Name       : IK
Gene ID             : ENSG00000113141.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: IK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IKENSG00000113141.17113.49107.44110.47ENCSR000AEF
HepG2IKENSG00000113141.1775.7884.2580.02ENCSR985KAT
K562IKENSG00000113141.17135.23136.36135.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IK is not avaliable on ENCORE database.



Proteins bound to RNA
  • IK RNA is bound by 24 proteins.  







eCLIP assay for IK is not avaliable on ENCORE database.





24 proteins are bound to IK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5140032565140032616+3'-UTR,CDS5.1021724.25325K562UCHL5
chr5140032673140032695+3'-UTR,CDS3.9448114.47170K562ZNF622
chr5140032636140032673+3'-UTR,CDS4.1757322.52583K562ZNF622
chr5140032653140032703+3'-UTR,CDS5.4063637.61232K562UCHL5
chr5140032658140032729+3'-UTR,CDS3.8122814.44156K562GRWD1
chr5140032563140032614+3'-UTR,CDS3.2587611.31993K562GRWD1
chr5140042026140042061+3'-UTR6.316318.89419K562PUM2
chr5140032644140032706+3'-UTR,CDS4.313107.06029HepG2GRWD1
chr5140041855140041913+3'-UTR,CDS,intron-Proximal4.336484.70425K562SMNDC1
chr5140032653140032732+3'-UTR,CDS,intron-Proximal3.1836617.96094K562ZNF800
chr5140032614140032658+3'-UTR,CDS4.3945615.88985K562GRWD1
chr5140041989140042057+3'-UTR5.433936.23813HepG2SUB1
chr5140032616140032653+3'-UTR,CDS5.7319525.48444K562UCHL5
chr5140032695140032730+3'-UTR,CDS,intron-Proximal3.8150818.60938K562ZNF622
chr5140032571140032644+3'-UTR,CDS3.565496.39282HepG2GRWD1
chr5140032561140032730+3'-UTR,CDS,intron-Proximal3.481327.25761HepG2FXR2
chr5140032609140032636+3'-UTR,CDS3.4759415.85918K562ZNF622
chr5140032642140032730+3'-UTR,CDS,intron-Proximal3.089144.62770HepG2HLTF
chr5140032618140032654+3'-UTR,CDS3.378917.32462K562PUM1
chr5140032703140032729+3'-UTR,CDS4.5070316.33279K562UCHL5
chr5140032565140032718+3'-UTR,CDS5.5128719.97376HepG2BCLAF1
chr5140027641140027693+5'-UTR,intron-Distal,intron-Proximal3.070215.54603K562PRPF8
chr5140027627140027699+5'-UTR,intron-Distal,intron-Proximal6.3533712.46423K562EIF4G2
chr5140027462140027487+5'-UTR,intron-Distal3.574274.92880K562ZNF622
chr5140041515140041541+CDS3.450085.39278K562ZNF622
chr5140034107140034130+CDS5.7015511.77442K562UCHL5
chr5140040342140040363+CDS,intron-Proximal5.9641013.64346K562UCHL5
chr5140041755140041807+CDS,intron-Proximal3.195564.95862K562EFTUD2
chr5140038666140038719+CDS3.546533.80299HepG2GRWD1
chr5140041764140041781+CDS3.8214010.26098K562UCHL5
chr5140041590140041659+CDS,intron-Proximal3.139914.04646K562PRPF8
chr5140039335140039362+CDS,intron-Proximal3.127143.18246K562PRPF8
chr5140041766140041797+CDS4.922596.04243HepG2BCLAF1
chr5140041163140041213+CDS,intron-Proximal4.4827011.32600K562AQR
chr5140041763140041780+CDS,intron-Proximal3.177576.19730K562ZNF622
chr5140041211140041260+CDS3.4298116.73582K562UCHL5
chr5140039340140039358+CDS,intron-Proximal4.173684.08604HepG2PPIG
chr5140038748140038754+CDS,intron-Proximal3.6603012.86452K562AQR
chr5140041238140041265+CDS3.911675.51703K562BUD13
chr5140038901140038981+CDS,intron-Proximal3.305217.65809K562PRPF8
chr5140038727140038750+CDS,intron-Proximal3.681197.15785K562GRWD1
chr5140038740140038750+CDS,intron-Proximal3.580295.10924K562ZNF800
chr5140038659140038696+CDS6.3544419.41650K562UCHL5
chr5140038530140038597+CDS3.424786.39282HepG2GRWD1
chr5140038633140038727+CDS3.1510319.66394K562GRWD1
chr5140038593140038616+CDS5.1060016.39416K562UCHL5
chr5140038734140038750+CDS,intron-Proximal4.073673.79199HepG2PPIG
chr5140041524140041579+CDS3.491475.86107HepG2PPIG
chr5140038719140038749+CDS4.362523.56019HepG2GRWD1
chr5140038900140038917+CDS3.478934.13746HepG2PPIG
chr5140041885140041902+CDS,intron-Proximal3.478933.86355HepG2PPIG
chr5140034298140034312+CDS3.496313.60157HepG2GRWD1
chr5140039344140039409+CDS3.378834.01163K562RBM15
chr5140035413140035451+CDS,intron-Proximal4.300627.09561HepG2BCLAF1
chr5140037138140037173+CDS,intron-Proximal4.234814.72880HepG2GRWD1
chr5140039398140039418+CDS4.149576.68017K562UCHL5
chr5140038883140038939+CDS,intron-Proximal4.3936631.52266K562AQR
chr5140038320140038360+CDS,intron-Proximal3.341143.81194K562TRA2A
chr5140041200140041248+CDS,intron-Proximal3.031784.09741HepG2PPIG
chr5140038598140038652+CDS3.2271010.97972K562ZNF622
chr5140038728140038749+CDS5.8053211.66235K562ZNF622
chr5140041752140041797+CDS,intron-Proximal3.775635.70278K562AQR
chr5140034298140034313+CDS,intron-Proximal3.378914.49042K562PUM1
chr5140033522140033543+CDS,intron-Proximal4.0724211.62230K562UCHL5
chr5140038904140038918+CDS6.3274220.60923K562UCHL5
chr5140041560140041592+CDS4.8164810.62510K562UCHL5
chr5140038721140038749+CDS5.4057817.85107K562UCHL5
chr5140028077140028118+CDS3.131107.93618K562UCHL5
chr5140039387140039419+CDS3.7559910.48558K562ZNF622
chr5140038896140038932+CDS,intron-Proximal3.098997.26020K562BUD13
chr5140034297140034312+CDS4.306584.60638K562GRWD1
chr5140038899140038904+CDS,intron-Proximal4.8669712.34367K562UCHL5
chr5140038652140038728+CDS4.2128117.81341K562ZNF622
chr5140038899140038917+CDS,intron-Proximal3.407383.80299HepG2GRWD1
chr5140034298140034313+CDS,intron-Proximal3.842124.93978HepG2BCLAF1
chr5140041204140041211+CDS,intron-Proximal3.7814212.10505K562UCHL5
chr5140040374140040400+CDS3.8752110.82249K562UCHL5
chr5140039293140039348+CDS,intron-Proximal3.965976.86590K562SF3B4
chr5140041558140041585+CDS3.483975.10924K562ZNF800
chr5140035519140035575+CDS4.652285.59408HepG2GRWD1
chr5140038899140038917+CDS,intron-Proximal3.800624.76554HepG2BCLAF1
chr5140038559140038593+CDS4.9883529.82545K562UCHL5
chr5140033522140033537+CDS,intron-Proximal4.1162110.40438K562ZNF622
chr5140035471140035499+CDS4.7092211.10249K562UCHL5
chr5140038696140038721+CDS5.2436915.81272K562UCHL5
chr5140039340140039376+CDS,intron-Proximal6.1820018.22511K562UCHL5
chr5140035413140035423+CDS,intron-Proximal3.251738.14373K562ZNF622
chr5140034297140034312+CDS3.4948013.21784K562UCHL5
chr5140041781140041797+CDS3.077436.65384K562UCHL5
chr5140041720140041776+CDS,intron-Proximal3.210276.52492K562SF3B4
chr5140039746140039780+CDS3.050518.73187K562ZNF622
chr5140035413140035454+CDS,intron-Proximal3.8510019.50833K562UCHL5
chr5140033622140033636+CDS5.318788.43384K562UCHL5
chr5140041579140041593+CDS,intron-Proximal4.051126.64430HepG2PPIG
chr5140039340140039371+CDS,intron-Proximal4.472047.82678K562ZNF622
chr5140039746140039781+CDS,intron-Proximal3.512874.09885HepG2BCLAF1
chr5140038616140038659+CDS5.4539820.65737K562UCHL5
chr5140039328140039373+CDS,intron-Proximal3.039075.47260HepG2AQR
chr5140041216140041271+CDS4.1812315.91368K562ZNF622
chr5140041566140041581+CDS3.690925.83654K562ZNF622
chr5140039774140039780+CDS5.0175613.64917K562UCHL5
chr5140038665140038730+CDS4.226303.84574HepG2TRA2A
chr5140035461140035507+CDS3.874567.64164K562YBX3
chr5140041580140041639+CDS,intron-Proximal4.940997.36776HepG2PRPF8
chr5140038527140038559+CDS4.8010225.80154K562UCHL5
chr5140035413140035445+CDS,intron-Proximal3.231606.56233K562PUM1
chr5140041204140041216+CDS,intron-Proximal4.0531712.90571K562ZNF622
chr5140039736140039779+CDS3.881563.95682K562PUM1
chr5140038525140038583+CDS3.341376.87198K562RBM15
chr5140040383140040400+CDS4.7194610.22656K562ZNF622
chr5140034100140034107+CDS,intron-Proximal5.302208.43384K562UCHL5
chr5140039744140039774+CDS5.1835815.84981K562UCHL5
chr5140035412140035519+CDS,intron-Proximal3.783799.36516HepG2GRWD1
chr5140041517140041588+CDS3.677345.52031HepG2GRWD1
chr5140035415140035461+CDS3.225726.15304K562YBX3
chr5140041763140041799+CDS,intron-Proximal4.434909.76012HepG2PPIG
chr5140038886140038937+CDS,intron-Proximal4.078479.76340HepG2AQR
chr5140038535140038591+CDS3.514444.56058HepG2BCLAF1
chr5140041557140041592+CDS4.859826.13315HepG2BCLAF1
chr5140034297140034312+CDS3.189079.27114K562ZNF622
chr5140034148140034169+CDS3.116794.28697K562ZNF622
chr5140041581140041592+CDS3.374087.28841K562ZNF622
chr5140040376140040421+CDS,intron-Proximal3.497355.32169K562EFTUD2
chr5140038609140038638+CDS4.274633.34184HepG2GRWD1
chr5140034299140034344+CDS,intron-Proximal4.180264.75655HepG2PRPF8
chr5140035414140035433+CDS4.416005.05331K562GRWD1
chr5140038899140038918+CDS,intron-Proximal4.8412813.00315K562ZNF622
chr5140041817140041904+CDS,intron-Proximal5.1668916.89670K562EFTUD2
chr5140039699140039725+CDS,intron-Proximal4.8077312.66167K562ZNF622
chr5140039896140039939+intron-Distal4.356064.19412K562EFTUD2
chr5140038950140039036+intron-Distal,intron-Proximal5.5740111.80896HepG2PRPF8
chr5140027879140028024+intron-Distal,intron-Proximal4.344265.44709K562KHSRP
chr5140038981140039061+intron-Distal,intron-Proximal4.630368.54286K562PRPF8
chr5140033655140033676+intron-Proximal5.346026.75320K562AQR
chr5140038943140039005+intron-Proximal5.455557.81704HepG2RBM22
chr5140038755140038792+intron-Proximal5.135774.83371K562EFTUD2
chr5140041606140041685+intron-Proximal6.061997.23906K562EFTUD2
chr5140033637140033655+intron-Proximal5.292566.75320K562AQR
chr5140038754140038792+intron-Proximal5.0386716.50383K562AQR
chr5140041596140041645+intron-Proximal3.574525.04653K562SF3B4
chr5140040449140040494+intron-Proximal4.939618.21918K562EFTUD2
chr5140038964140038997+intron-Proximal6.4009218.17544K562AQR
chr5140041592140041595+intron-Proximal3.784594.52312K562AQR
chr5140040401140040443+intron-Proximal5.234827.63570K562AQR
chr5140038939140038964+intron-Proximal7.1566726.38897K562AQR
chr5140040445140040489+intron-Proximal4.158655.28701K562PRPF8
chr5140038965140039011+intron-Proximal3.247873.29548K562XRN2
chr5140041595140041633+intron-Proximal4.234826.77156K562AQR
chr5140038946140038989+intron-Proximal3.309435.85200K562BUD13
chr5140038937140038962+intron-Proximal5.037537.09786HepG2AQR
chr5140035578140035621+intron-Proximal4.033647.90583K562AQR
chr5140037250140037289+intron-Proximal4.945565.26064K562AQR
chr5140038924140038975+intron-Proximal3.571134.37001K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IK is not available on ENCORE database.

  • 56 RBPs can affect the levels of IK.  








The Knockdown/knockout RNA-Seq assay for IK is not available on ENCORE database.





56 RBPs can affect the gene expression of IK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IKENSG00000113141.113279.418401965.958200.738108.413607.54130HepG2AKAP1
IKENSG00000113141.111225.855901467.37150-0.259402.730401.96820HepG2AKAP8L
IKENSG00000113141.11986.230301305.25090-0.404302.621101.74400HepG2BCLAF1
IKENSG00000113141.112078.008102760.86930-0.409904.308203.57970HepG2BOP1
IKENSG00000113141.112831.004103765.65120-0.411602.765201.79040HepG2CCAR1
IKENSG00000113141.111911.357201460.207400.388307.441906.45030HepG2CKAP4
IKENSG00000113141.112026.339002534.61400-0.322902.599001.93000HepG2CPSF6
IKENSG00000113141.112176.053402556.67800-0.232603.239602.44860HepG2DAZAP1
IKENSG00000113141.111615.014501397.264900.208801.981701.39380HepG2DKC1
IKENSG00000113141.111094.674501490.70410-0.445506.163605.14740HepG2DNAJC21
IKENSG00000113141.111167.243001477.66590-0.340205.293504.43620HepG2DNAJC2
IKENSG00000113141.111256.823901555.10240-0.307201.982501.47070HepG2EIF2S1
IKENSG00000113141.111898.647102416.40400-0.347902.840702.01590HepG2EIF4G2
IKENSG00000113141.111711.853301404.868000.285002.232301.51910HepG2FUBP3
IKENSG00000113141.11889.298201394.35240-0.6489013.3695011.48270HepG2HDGF
IKENSG00000113141.112079.688202480.07760-0.254003.039502.29010HepG2HNRNPF
IKENSG00000113141.112039.055301629.120200.323702.531701.86180HepG2HNRNPK
IKENSG00000113141.111986.366602328.85510-0.229502.969102.27310HepG2HNRNPL
IKENSG00000113141.112209.403002741.89690-0.311502.094901.53900HepG2HNRNPLL
IKENSG00000113141.111895.779301662.990200.188901.904801.39270HepG2HNRNPU
IKENSG00000113141.111290.657701634.98760-0.341202.334101.70870HepG2IGF2BP2
IKENSG00000113141.111151.580101335.07710-0.213302.274001.34750HepG2KIF1C
IKENSG00000113141.112169.603302535.21120-0.224701.952201.30900HepG2NOL12
IKENSG00000113141.111172.041101589.91550-0.439903.458102.65690HepG2PABPC4
IKENSG00000113141.112387.374301778.734400.424502.340001.38210HepG2PCBP2
IKENSG00000113141.111848.372402420.15660-0.388803.993503.29240HepG2PUF60
IKENSG00000113141.112257.589702569.19160-0.186502.272601.72450HepG2PUM1
IKENSG00000113141.111287.176501487.56240-0.208702.071501.52040HepG2PUS1
IKENSG00000113141.112501.399601716.680300.543002.899002.17940HepG2RAVER1
IKENSG00000113141.113567.514502711.877200.395502.450501.81680HepG2SF3A3
IKENSG00000113141.112123.982402713.91350-0.353603.380902.60800HepG2SF3B1
IKENSG00000113141.111793.378802320.73460-0.371907.076506.03760HepG2SLBP
IKENSG00000113141.112818.988802351.154000.261704.007203.43690HepG2SRFBP1
IKENSG00000113141.112734.203801797.284400.6052016.9031015.94450HepG2SRSF1
IKENSG00000113141.111802.480101462.236400.301704.377103.71280HepG2SRSF9
IKENSG00000113141.112358.769902717.60890-0.204302.563401.96010HepG2SUCLG1
IKENSG00000113141.111816.766701470.214900.305201.988501.40130HepG2SUPV3L1
IKENSG00000113141.111996.638102672.60510-0.420704.311403.43270HepG2TARDBP
IKENSG00000113141.111952.995902364.53510-0.275902.315201.52250HepG2TUFM
IKENSG00000113141.113069.761602319.282000.404303.598202.88530HepG2U2AF1
IKENSG00000113141.112020.974602405.01760-0.251003.596102.81580HepG2UPF1
IKENSG00000113141.111914.900802321.95440-0.278103.994403.29410HepG2UTP3
IKENSG00000113141.111836.978001447.264000.343902.648901.93980HepG2XRN2
IKENSG00000113141.116115.466005218.157000.228803.742503.10080K562AGGF1
IKENSG00000113141.112305.567702689.43600-0.222202.779401.81730K562BCLAF1
IKENSG00000113141.115384.736306297.89470-0.226003.250302.04400K562CPEB4
IKENSG00000113141.117356.245406516.013700.174902.365101.75540K562DDX47
IKENSG00000113141.116751.287705842.797400.208402.587001.74440K562DKC1
IKENSG00000113141.113618.676902448.234800.563607.235405.70190K562EFTUD2
IKENSG00000113141.115473.012506649.82800-0.281004.528503.33880K562EIF4G2
IKENSG00000113141.112714.150102388.114700.184501.839701.32640K562FXR1
IKENSG00000113141.114289.410705230.01100-0.286003.055802.26360K562GRSF1
IKENSG00000113141.112762.191903661.04340-0.406404.451003.71230K562HNRNPC
IKENSG00000113141.113903.315003014.168600.372803.247701.89850K562HNRNPK
IKENSG00000113141.114396.857503627.708000.277303.569102.55380K562HNRNPU
IKENSG00000113141.116716.661505762.308900.221002.126001.41340K562KIF1C
IKENSG00000113141.114187.695305063.18230-0.273905.039603.97410K562MTPAP
IKENSG00000113141.113691.333802822.068300.387304.211702.99900K562PCBP2
IKENSG00000113141.114013.588902382.418600.7524012.2944010.70690K562PRPF8
IKENSG00000113141.117695.305005384.825600.515007.118806.29390K562PUS1
IKENSG00000113141.116089.022905246.677900.214702.334401.78190K562RBM15
IKENSG00000113141.113049.147102426.640500.329302.345101.59570K562RPS19
IKENSG00000113141.115010.089105687.08470-0.182903.102302.11670K562SRPK2
IKENSG00000113141.113324.707202648.165700.328102.955301.30820K562TBRG4
IKENSG00000113141.114825.906505965.17460-0.305806.257805.22900K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IK is not available on ENCORE database.





1 RBPs can affect the splicing of IK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIKENSG00000113141.11chr5+140035413140035513140034071140034312140037138140037247-0.052000.001340.01565excludedK562AQR
A3SSIKENSG00000113141.11chr5+1400417421400417981400417631400417981400414161400415920.052000.000000.00000longerK562AQR
A3SSIKENSG00000113141.11chr5+1400385051400387491400385231400387491400383211400383610.051000.000000.00000longerK562AQR
A3SSIKENSG00000113141.11chr5+1400316511400317321400316721400317321400312981400313910.071000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IK is not avaliable on ENCORE database.