DNAJC1

General Information

Gene Name       : DNAJC1
Gene ID             : ENSG00000136770.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DNAJC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DNAJC1ENSG00000136770.1014.5613.7714.16ENCSR000AEF
HepG2DNAJC1ENSG00000136770.108.3310.569.45ENCSR985KAT
K562DNAJC1ENSG00000136770.1038.1926.6832.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
DNAJC1A304-055A1BGHcLV39-27, Submitted, ENCORE2BGKcLV38-19, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DNAJC1K562CRISPRDNAJC1-BGKcLV38-19,DNAJC1-BGKcLV38-20NT-BGKcLV38-1,NT-BGKcLV38-263.5,65.4SubmittingENCORE2
DNAJC1HepG2CRISPRDNAJC1-BGHcLV39-27,DNAJC1-BGHcLV39-28NT-BGHcLV39-1,NT-BGHcLV39-262.3,70.6SubmittingENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
DNAJC1Product_ID: A304-055A
Lot_ID: 1
Source: Bethyl Labs
Target Name: DNAJC1-human		 DNAJC1-hepg2-CRISPR-A304-055A.png<br>Caption: Western blot following CRISPR against DNAJC1 in HepG2 whole cell lysate using DNAJC1 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against DNAJC1. DNAJC1 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 DNAJC1-K562-CRISPR-A304-055A.png<br>Caption: Western blot following CRISPR against DNAJC1 in K562 whole cell lysate using DNAJC1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against DNAJC1. DNAJC1 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for DNAJC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DNAJC1 RNA is bound by 13 proteins.  







eCLIP assay for DNAJC1 is not avaliable on ENCORE database.





13 proteins are bound to DNAJC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr102220981922209876-3'-UTR,CDS,intron-Distal3.419433.07497K562SND1
chr102220983422209889-3'-UTR,CDS,intron-Distal3.839573.65778K562GRWD1
chr102220973622209780-3'-UTR,CDS,intron-Distal3.878973.02572K562SND1
chr102220876122208831-3'-UTR,CDS,intron-Distal,intron-Proximal4.6819411.26582K562ZNF622
chr102229246922292528-5'-UTR,intron-Distal,intron-Proximal5.586237.49422HepG2DDX3X
chr102229255722292643-5'-UTR,intron-Distal,intron-Proximal4.892728.17272HepG2DDX3X
chr102229214122292169-CDS,intron-Distal3.167154.33023K562ZNF622
chr102221804822218070-CDS,intron-Distal3.978376.14226K562ZNF622
chr102220775722207800-CDS,intron-Distal3.789118.04012K562ZNF622
chr102211406422114134-intron-Distal3.738603.43228K562SAFB2
chr102208021122080263-intron-Distal4.196273.30687K562EXOSC5
chr102207953522079602-intron-Distal4.121903.78162K562HNRNPM
chr102209245322092642-intron-Distal3.4771511.14072K562AGGF1
chr102217565122175686-intron-Distal4.389794.80399K562EXOSC5
chr102215520522155252-intron-Distal3.724583.45805K562KHSRP
chr102215436822154445-intron-Distal3.350564.10408K562KHSRP
chr102209253722092631-intron-Distal4.145413.02891HepG2HNRNPL
chr102217500222175043-intron-Distal4.691643.89080K562EXOSC5
chr102207625622076314-intron-Distal5.517058.93487K562PTBP1
chr102217506122175108-intron-Distal4.233817.61465K562EXOSC5
chr102223073522230801-intron-Distal5.095144.38664K562QKI
chr102217405522174108-intron-Distal4.507025.12432K562EXOSC5
chr102207467222074736-intron-Distal4.622804.90095K562PTBP1
chr102221077022210864-intron-Distal3.749743.24603K562KHSRP
chr102223121822231291-intron-Distal3.982085.14864K562KHSRP
chr102208747122087585-intron-Distal4.213614.51328K562SAFB2
chr102207802422078113-intron-Distal4.259724.51377K562HNRNPM
chr102222643522226486-intron-Distal3.317093.07751K562KHSRP
chr102211613122116222-intron-Distal3.734283.19638K562SAFB2
chr102214464922144717-intron-Distal4.111153.31153K562GTF2F1
chr102221727522217299-intron-Distal3.609104.08064K562KHSRP
chr102219972322199785-intron-Distal5.431147.72823K562PTBP1
chr102211181522111925-intron-Distal5.219106.75921K562QKI
chr102220887422208997-intron-Distal,intron-Proximal3.850565.78005K562KHSRP
chr102215429622154368-intron-Distal3.285923.46531K562KHSRP
chr102209244822092622-intron-Distal3.9911212.70998K562HNRNPL
chr102222648622226601-intron-Distal3.812148.04002K562KHSRP
chr102217532922175392-intron-Distal4.167987.91405K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DNAJC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DNAJC1 is not available on ENCORE database.

  • 84 RBPs can affect the levels of DNAJC1.  








The Knockdown/knockout RNA-Seq assay for DNAJC1 is not available on ENCORE database.





84 RBPs can affect the gene expression of DNAJC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DNAJC1ENSG00000136770.6394.63080291.217500.438303.084602.44770HepG2ACO1
DNAJC1ENSG00000136770.6688.49960433.106800.668604.569103.90740HepG2AKAP1
DNAJC1ENSG00000136770.6499.99300366.843800.446603.542102.78250HepG2AUH
DNAJC1ENSG00000136770.6434.99740244.676600.830005.634504.27870HepG2BCCIP
DNAJC1ENSG00000136770.6348.63610212.630600.713304.273503.17850HepG2BCLAF1
DNAJC1ENSG00000136770.6540.00880280.111000.946909.678908.64660HepG2BOP1
DNAJC1ENSG00000136770.6354.56720258.446700.456102.618101.42340HepG2BUD13
DNAJC1ENSG00000136770.6433.03770272.195700.669705.307304.28170HepG2CALR
DNAJC1ENSG00000136770.6426.64970291.170600.551104.841904.00890HepG2CKAP4
DNAJC1ENSG00000136770.6546.03720335.677200.701807.971506.98730HepG2CELF1
DNAJC1ENSG00000136770.6454.31950360.900300.332002.426201.72580HepG2DAZAP1
DNAJC1ENSG00000136770.6571.50080414.886700.461902.620402.01020HepG2DDX3X
DNAJC1ENSG00000136770.6481.24760356.388700.433202.025101.48910HepG2DDX6
DNAJC1ENSG00000136770.6406.49650278.620400.544804.019603.23290HepG2DKC1
DNAJC1ENSG00000136770.6337.26430233.247200.531902.362801.34480HepG2AGO1
DNAJC1ENSG00000136770.6463.46850356.080500.380202.660401.83650HepG2EIF4G1
DNAJC1ENSG00000136770.6490.94610341.096900.525302.574201.78710HepG2EIF4G2
DNAJC1ENSG00000136770.6379.58420284.586000.415502.262801.50790HepG2EWSR1
DNAJC1ENSG00000136770.6140.04260257.59720-0.879302.622301.63480HepG2FTO
DNAJC1ENSG00000136770.6270.48360365.33390-0.433702.504801.82120HepG2HNRNPF
DNAJC1ENSG00000136770.6267.64620358.82590-0.423001.899301.31490HepG2HNRNPK
DNAJC1ENSG00000136770.6378.55890278.193600.444302.090001.53480HepG2HNRNPLL
DNAJC1ENSG00000136770.6325.84450240.323600.439102.305401.43740HepG2HNRNPM
DNAJC1ENSG00000136770.6377.47340240.701700.649005.599504.76220HepG2HNRNPU
DNAJC1ENSG00000136770.6497.70650360.219200.466302.627701.96750HepG2IGF2BP2
DNAJC1ENSG00000136770.6627.53770281.924401.1543015.4837013.74120HepG2MSI2
DNAJC1ENSG00000136770.6283.28630393.33910-0.473502.237501.66520HepG2NCBP2
DNAJC1ENSG00000136770.6330.45290200.778000.718703.060502.12480HepG2PABPC1
DNAJC1ENSG00000136770.6316.70190214.687200.560803.671402.83470HepG2PPIL4
DNAJC1ENSG00000136770.6284.74570185.641000.617103.144802.28860HepG2PRPF8
DNAJC1ENSG00000136770.6597.17990362.392400.720507.661806.56900HepG2PUM2
DNAJC1ENSG00000136770.6444.53880296.626300.583605.319404.51530HepG2PUS1
DNAJC1ENSG00000136770.6125.95510403.47610-1.6796022.5514021.01600HepG2QKI
DNAJC1ENSG00000136770.6635.92240271.541001.227608.837007.62290HepG2RAVER1
DNAJC1ENSG00000136770.6269.10150386.09350-0.520803.671502.97470HepG2RECQL
DNAJC1ENSG00000136770.6275.76400387.86280-0.492103.311702.67130HepG2SF3B4
DNAJC1ENSG00000136770.6477.57280306.383500.640302.734501.95800HepG2SNRNP70
DNAJC1ENSG00000136770.6486.73310397.606400.291701.727701.30290HepG2SRFBP1
DNAJC1ENSG00000136770.6313.50550404.82970-0.368802.146701.71520HepG2SRSF1
DNAJC1ENSG00000136770.6436.93770337.321400.373202.541501.93680HepG2SRSF5
DNAJC1ENSG00000136770.6484.00850345.221000.487404.176003.57310HepG2SSB
DNAJC1ENSG00000136770.6317.80060191.677700.729304.063302.70910HepG2STIP1
DNAJC1ENSG00000136770.6492.66150383.615600.360802.682502.06770HepG2SUCLG1
DNAJC1ENSG00000136770.6363.34080235.218300.627204.267203.11160HepG2SUPT6H
DNAJC1ENSG00000136770.6361.73260239.489400.594903.150002.43320HepG2SUPV3L1
DNAJC1ENSG00000136770.6224.42500363.83500-0.697103.989403.33500HepG2TAF15
DNAJC1ENSG00000136770.6425.72530235.976900.851209.624108.67050HepG2TRIM56
DNAJC1ENSG00000136770.6411.12170297.946500.464402.464301.86900HepG2U2AF1
DNAJC1ENSG00000136770.6489.69200338.705800.531704.840003.95730HepG2UPF1
DNAJC1ENSG00000136770.6486.27990348.145900.482003.865502.64690HepG2UTP18
DNAJC1ENSG00000136770.6419.81500327.007900.360302.101001.56490HepG2UTP3
DNAJC1ENSG00000136770.6293.03500180.595900.698205.121304.25580HepG2ZC3H8
DNAJC1ENSG00000136770.6568.63060372.512200.610107.372406.59090HepG2ZNF622
DNAJC1ENSG00000136770.6938.87830603.173400.638306.794904.89660K562AARS
DNAJC1ENSG00000136770.61163.124801530.22810-0.395705.351304.60400K562AGGF1
DNAJC1ENSG00000136770.6596.898201345.30810-1.1724019.3236017.94150K562AQR
DNAJC1ENSG00000136770.62357.368901828.676700.366304.492902.95020K562CCDC124
DNAJC1ENSG00000136770.61371.08960957.620900.517705.346003.57910K562CIRBP
DNAJC1ENSG00000136770.61494.992202016.35640-0.431605.976204.54960K562CELF1
DNAJC1ENSG00000136770.61785.003601244.991800.519706.296105.37020K562DDX47
DNAJC1ENSG00000136770.6724.72620500.433600.534203.109501.74670K562EEF2
DNAJC1ENSG00000136770.61536.37980964.607100.6714013.2196011.82980K562EIF2S2
DNAJC1ENSG00000136770.6845.92700517.639100.708504.588803.21700K562EIF3D
DNAJC1ENSG00000136770.6968.37420775.081100.321102.267801.52240K562EIF4A3
DNAJC1ENSG00000136770.61321.482201639.60920-0.311203.684202.60060K562EIF4G2
DNAJC1ENSG00000136770.6390.33410536.42400-0.458703.345601.93510K562EXOSC5
DNAJC1ENSG00000136770.6563.96080876.09390-0.635508.299406.41060K562GLRX3
DNAJC1ENSG00000136770.6982.653001285.51400-0.387603.281902.46130K562GRSF1
DNAJC1ENSG00000136770.6630.07130802.24570-0.348502.578501.54060K562HNRNPA1
DNAJC1ENSG00000136770.6492.27360659.96600-0.422902.927002.31520K562HNRNPC
DNAJC1ENSG00000136770.6777.774401125.15630-0.532705.846704.25040K562HNRNPL
DNAJC1ENSG00000136770.6941.59410649.706900.535204.014602.87880K562HNRNPM
DNAJC1ENSG00000136770.61073.74250888.439100.273202.282801.47000K562HNRNPU
DNAJC1ENSG00000136770.61666.365401070.969700.637707.767906.45170K562HSPD1
DNAJC1ENSG00000136770.6719.11160937.12440-0.382003.186102.19090K562MATR3
DNAJC1ENSG00000136770.6662.15110921.10850-0.476206.045904.88720K562MTPAP
DNAJC1ENSG00000136770.6701.256401023.37800-0.545309.263108.00580K562NSUN2
DNAJC1ENSG00000136770.6731.63450470.497200.636805.259604.22530K562PRPF8
DNAJC1ENSG00000136770.6447.08030591.73190-0.404402.126201.34400K562PSIP1
DNAJC1ENSG00000136770.6755.75190912.33440-0.271601.880901.31450K562PTBP1
DNAJC1ENSG00000136770.61894.794001579.040300.262901.928101.45920K562PUS1
DNAJC1ENSG00000136770.6538.66280803.88980-0.577605.654903.02180K562QKI
DNAJC1ENSG00000136770.6713.09030479.227100.573303.945202.96690K562RPS19
DNAJC1ENSG00000136770.6655.53860918.72950-0.487003.429901.35880K562SAFB2
DNAJC1ENSG00000136770.6825.261201009.89660-0.291302.336901.58180K562SF3A3
DNAJC1ENSG00000136770.6414.35140599.02440-0.531802.306401.42700K562SF3B1
DNAJC1ENSG00000136770.6483.40900746.97710-0.627806.459905.11580K562SF3B4
DNAJC1ENSG00000136770.6777.980201034.66840-0.411405.288804.04470K562SRPK2
DNAJC1ENSG00000136770.6620.61620947.95980-0.611105.424903.58530K562STAU1
DNAJC1ENSG00000136770.6738.28690524.945900.491904.543203.48350K562SYNCRIP
DNAJC1ENSG00000136770.6418.89250569.14520-0.442202.506301.61990K562TIAL1
DNAJC1ENSG00000136770.6434.32020604.66090-0.477403.424502.35040K562TRIM56
DNAJC1ENSG00000136770.61382.326601085.113800.349204.661503.75380K562UPF1
DNAJC1ENSG00000136770.61166.49630965.572200.272602.995802.11500K562WDR43
DNAJC1ENSG00000136770.61225.451201515.55280-0.306502.413101.61630K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DNAJC1 is not available on ENCORE database.





7 RBPs can affect the splicing of DNAJC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDNAJC1ENSG00000136770.6chr10-2221743422217481222097262220989222217968222180700.111000.000000.00010includedK562HNRNPU
SEDNAJC1ENSG00000136770.6chr10-222174342221748122208831222088582221796822218070-0.160000.000480.02283excludedK562SF3B1
SEDNAJC1ENSG00000136770.6chr10-2216867222168812220949082209502822171210221713680.101000.000000.00000includedK562HNRNPC
A3SSDNAJC1ENSG00000136770.6chr10-2205518922055351220551892205523822094908220950280.087000.000000.00000longerK562AQR
MXEDNAJC1ENSG00000136770.6chr10-2217121022171363221934502219354122094908220950282220770722207801-0.111000.002140.030542includedK562DROSHA
MXEDNAJC1ENSG00000136770.6chr10-2209490822095028221712102217136822055189220552382219345022193541-0.101000.007870.074092includedK562DROSHA
MXEDNAJC1ENSG00000136770.6chr10-2205518922055238220949852209502822048437220485472217121022171368-0.137000.000330.021372includedK562TIA1
MXEDNAJC1ENSG00000136770.6chr10-2217121022171363221934502219354122094908220950282220770722207801-0.107000.004910.062112includedK562HNRNPUL1
MXEDNAJC1ENSG00000136770.6chr10-2209490822095028221712102217136822055189220552382219345022193541-0.103000.009820.095672includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DNAJC1 is not avaliable on ENCORE database.