DEGS1

General Information

Gene Name       : DEGS1
Gene ID             : ENSG00000143753.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DEGS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DEGS1ENSG00000143753.1245.3239.3542.34ENCSR000AEF
HepG2DEGS1ENSG00000143753.1213.7725.5419.66ENCSR985KAT
K562DEGS1ENSG00000143753.1240.5947.1643.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DEGS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DEGS1 RNA is bound by 7 proteins.  







eCLIP assay for DEGS1 is not avaliable on ENCORE database.





7 proteins are bound to DEGS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1224380591224380697+3'-UTR,intron-Proximal5.0176528.42816HepG2UPF1
chr1224380967224381019+3'-UTR4.702107.90397K562PABPC4
chr1224380779224380831+3'-UTR6.0747310.19274K562PABPC4
chr1224370977224371056+5'-UTR,CDS,intron-Distal4.121147.76798K562DDX3X
chr1224370948224371116+5'-UTR,CDS,intron-Distal4.1317610.03874HepG2DDX3X
chr1224371056224371116+CDS,intron-Distal3.191705.21590K562DDX3X
chr1224377552224377630+CDS6.1112112.88556K562SND1
chr1224377462224377552+CDS3.527815.51805K562SND1
chr1224377630224377680+CDS4.319986.47873K562SND1
chr1224377318224377387+CDS4.033955.47892K562DDX3X
chr1224377668224377794+CDS3.101273.57062K562IGF2BP1
chr1224377952224378018+CDS3.642805.04716K562SND1
chr1224377276224377318+CDS,intron-Proximal4.352673.01143K562DDX3X
chr1224377799224377897+CDS3.039946.72029K562SND1
chr1224377810224377888+CDS3.034893.89082K562TIA1
chr1224377680224377799+CDS3.633487.35442K562SND1
chr1224380035224380080+CDS3.925964.38503K562SND1
chr1224376870224377028+intron-Distal4.200308.55611K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DEGS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DEGS1 is not available on ENCORE database.

  • 77 RBPs can affect the levels of DEGS1.  








The Knockdown/knockout RNA-Seq assay for DEGS1 is not available on ENCORE database.





77 RBPs can affect the gene expression of DEGS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DEGS1ENSG00000143753.8828.12330470.733100.814806.512205.66010HepG2ACO1
DEGS1ENSG00000143753.81420.32890721.857000.9763011.5144010.50170HepG2AKAP1
DEGS1ENSG00000143753.8960.76620617.951100.636609.893608.72940HepG2AUH
DEGS1ENSG00000143753.8575.01060337.504700.768607.157706.24790HepG2BOP1
DEGS1ENSG00000143753.8476.04810322.587800.561303.918602.46090HepG2BUD13
DEGS1ENSG00000143753.8565.21290356.387200.665206.403805.29290HepG2CALR
DEGS1ENSG00000143753.8296.69690508.79820-0.778104.356603.39290HepG2CNOT7
DEGS1ENSG00000143753.8508.33880309.857700.714104.694103.81980HepG2CPSF6
DEGS1ENSG00000143753.81347.15420621.066601.1170029.9946028.35210HepG2CELF1
DEGS1ENSG00000143753.8614.41410379.859100.693607.758805.96080HepG2DDX1
DEGS1ENSG00000143753.8451.70820332.768900.440802.249101.43570HepG2DDX24
DEGS1ENSG00000143753.81648.09470691.533201.2528021.6371020.06320HepG2DDX3X
DEGS1ENSG00000143753.8161.40960269.33040-0.738703.793802.22190HepG2DDX52
DEGS1ENSG00000143753.8537.52210364.559400.560103.952302.75260HepG2DDX5
DEGS1ENSG00000143753.8898.01480593.926500.596404.363703.60230HepG2DDX6
DEGS1ENSG00000143753.8478.83850372.466200.362302.371901.71500HepG2DNAJC21
DEGS1ENSG00000143753.8234.16770369.21170-0.656905.924705.02400HepG2DNAJC2
DEGS1ENSG00000143753.8544.23540313.167600.797204.614403.17720HepG2AGO1
DEGS1ENSG00000143753.8365.36520260.926400.485602.327201.49200HepG2EIF3D
DEGS1ENSG00000143753.8475.38400631.15450-0.408902.139901.57490HepG2EIF4A3
DEGS1ENSG00000143753.8333.28340233.148900.515403.150201.89020HepG2FAM120A
DEGS1ENSG00000143753.8586.36310434.758700.431502.198601.50880HepG2FIP1L1
DEGS1ENSG00000143753.8516.51630334.506000.626703.878502.39260HepG2FKBP4
DEGS1ENSG00000143753.8699.99210430.440400.701403.662502.04780HepG2HLTF
DEGS1ENSG00000143753.8425.26230546.76560-0.362602.640901.93970HepG2HNRNPF
DEGS1ENSG00000143753.8512.69660335.226000.612904.202303.44190HepG2HNRNPLL
DEGS1ENSG00000143753.8451.86400299.969000.591004.270303.11320HepG2HNRNPM
DEGS1ENSG00000143753.8613.75430439.632800.481302.663801.45990HepG2HSPD1
DEGS1ENSG00000143753.8402.34700538.40840-0.420302.904702.16330HepG2IGF2BP1
DEGS1ENSG00000143753.8662.78320439.239500.593403.559602.13870HepG2KRR1
DEGS1ENSG00000143753.8514.30890351.871800.547503.891602.93590HepG2MSI2
DEGS1ENSG00000143753.8979.82280655.563100.579704.637303.82910HepG2NCBP2
DEGS1ENSG00000143753.8966.37680464.954901.055408.031306.47230HepG2PABPC1
DEGS1ENSG00000143753.8244.18080370.60370-0.601904.559203.63550HepG2PPIL4
DEGS1ENSG00000143753.8205.41760275.73170-0.424702.141501.45340HepG2PRPF4
DEGS1ENSG00000143753.8467.07750310.042800.591103.639802.72790HepG2PRPF8
DEGS1ENSG00000143753.8870.76960671.045600.375804.128103.43490HepG2PUM1
DEGS1ENSG00000143753.8969.22130670.571300.531305.603804.66310HepG2PUM2
DEGS1ENSG00000143753.8665.28160410.630100.696003.428402.64610HepG2RAVER1
DEGS1ENSG00000143753.8436.84650552.84660-0.339802.086501.32830HepG2RBM15
DEGS1ENSG00000143753.81012.33490592.975700.7715012.8456011.89280HepG2RBM22
DEGS1ENSG00000143753.8422.52830582.29470-0.462704.044603.31810HepG2RECQL
DEGS1ENSG00000143753.8459.11050588.99410-0.359402.082201.47980HepG2RPLP0
DEGS1ENSG00000143753.8273.12890403.24120-0.562102.515901.61240HepG2RPS10
DEGS1ENSG00000143753.8485.17360306.699500.661604.141403.20220HepG2RRP9
DEGS1ENSG00000143753.8469.13680370.027300.342302.362801.76030HepG2SAFB2
DEGS1ENSG00000143753.8703.01670474.243400.567803.593402.82140HepG2SF3A3
DEGS1ENSG00000143753.81151.69510369.206001.6412011.9864010.36910HepG2SNRNP70
DEGS1ENSG00000143753.8953.76670669.760200.509905.773405.12310HepG2SRFBP1
DEGS1ENSG00000143753.8719.52340496.685000.534606.375505.59910HepG2SRSF9
DEGS1ENSG00000143753.8883.62470709.845700.315802.949302.31150HepG2SUCLG1
DEGS1ENSG00000143753.8577.32650293.575500.9756011.8618010.04360HepG2SUPT6H
DEGS1ENSG00000143753.8604.41240400.067100.595203.826203.05060HepG2SUPV3L1
DEGS1ENSG00000143753.8506.64460326.668800.633004.727003.81420HepG2TARDBP
DEGS1ENSG00000143753.8407.78440268.156300.604603.059402.01480HepG2TFIP11
DEGS1ENSG00000143753.8634.68200504.245800.331802.131601.39600HepG2TIA1
DEGS1ENSG00000143753.8600.58770407.362000.560006.192505.40970HepG2TRIM56
DEGS1ENSG00000143753.8532.89440371.911600.518803.114302.44980HepG2U2AF1
DEGS1ENSG00000143753.8877.92040653.646800.425502.408001.63120HepG2UBE2L3
DEGS1ENSG00000143753.8397.15640236.338000.748805.465004.39180HepG2UCHL5
DEGS1ENSG00000143753.8584.04250406.055200.524304.907604.14870HepG2UTP3
DEGS1ENSG00000143753.8903.23200462.559300.9654022.9184021.72390HepG2ZNF622
DEGS1ENSG00000143753.81789.130401334.362500.423003.090901.77740K562APOBEC3C
DEGS1ENSG00000143753.82162.109201859.017300.217802.180601.31640K562CELF1
DEGS1ENSG00000143753.8391.06610640.74430-0.712304.494801.55890K562DDX52
DEGS1ENSG00000143753.81044.83920602.599500.7939012.7103011.50940K562FXR1
DEGS1ENSG00000143753.8972.71230604.569300.686003.855302.98930K562G3BP2
DEGS1ENSG00000143753.8383.02450714.65010-0.899806.430605.55750K562HNRNPC
DEGS1ENSG00000143753.81024.88740799.815900.357602.981802.10860K562MAGOH
DEGS1ENSG00000143753.8555.04380708.11640-0.351402.268901.47710K562METAP2
DEGS1ENSG00000143753.8763.80500578.616400.400503.217701.88540K562NCBP2
DEGS1ENSG00000143753.8751.65520887.44430-0.239602.160201.49250K562NSUN2
DEGS1ENSG00000143753.8325.41530504.80980-0.633502.405601.49620K562PABPN1
DEGS1ENSG00000143753.8739.71820573.670600.366702.821502.01150K562POLR2G
DEGS1ENSG00000143753.8939.29220611.195700.619805.847504.75510K562PRPF8
DEGS1ENSG00000143753.81379.68710777.060200.8281014.7383013.26730K562PTBP1
DEGS1ENSG00000143753.82525.190901649.938400.613909.077407.58640K562PUF60
DEGS1ENSG00000143753.82169.657301754.675600.306203.539402.32360K562PUM1
DEGS1ENSG00000143753.8525.40870702.54860-0.419203.865102.00850K562RPS10
DEGS1ENSG00000143753.8852.13760575.398200.566406.203104.96650K562SYNCRIP
DEGS1ENSG00000143753.8426.61560616.28570-0.530702.948701.98070K562TIAL1
DEGS1ENSG00000143753.8469.25870654.48170-0.480002.576901.67050K562TRIM56
DEGS1ENSG00000143753.8785.59560605.674100.375103.156602.29930K562U2AF2
DEGS1ENSG00000143753.8628.90340805.16330-0.356402.635501.77930K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DEGS1 is not available on ENCORE database.





1 RBPs can affect the splicing of DEGS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDEGS1ENSG00000143753.8chr1+2243787932243788582243778372243780212243800332243801420.065000.007770.09694includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DEGS1 is not avaliable on ENCORE database.