CRLF1

General Information

Gene Name       : CRLF1
Gene ID             : ENSG00000006016.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CRLF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CRLF1ENSG00000006016.100.250.000.12ENCSR000AEF
HepG2CRLF1ENSG00000006016.10529.78147.46338.62ENCSR985KAT
K562CRLF1ENSG00000006016.100.650.820.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CRLF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CRLF1 RNA is bound by 24 proteins.  







eCLIP assay for CRLF1 is not avaliable on ENCORE database.





24 proteins are bound to CRLF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191870411018704206-3'-UTR,intron-Distal4.3849081.48577HepG2LARP4
chr191870411318704169-3'-UTR,intron-Distal3.418969.08495HepG2DDX6
chr191870409518704181-3'-UTR,intron-Distal4.4694811.29390HepG2AKAP1
chr191870418918704325-3'-UTR,intron-Distal6.5845725.04886HepG2UPF1
chr191870434318704373-3'-UTR,intron-Distal3.6153615.03648HepG2RPS3
chr191870411318704165-3'-UTR,intron-Distal5.032969.30447HepG2UPF1
chr191870432118704389-3'-UTR,CDS,intron-Distal3.0097114.30475HepG2DDX55
chr191870420618704298-3'-UTR,intron-Distal4.6155138.21120HepG2LARP4
chr191870431018704379-3'-UTR,intron-Distal3.8847738.87202HepG2LARP4
chr191870419718704294-3'-UTR,intron-Distal4.2771612.62672HepG2AKAP1
chr191870432518704447-3'-UTR,CDS,intron-Distal4.3818118.85546HepG2UPF1
chr191870422518704316-3'-UTR,intron-Distal3.1669410.33710HepG2YBX3
chr191870433318704390-3'-UTR,CDS,intron-Distal3.419959.58752HepG2DDX6
chr191870432718704378-3'-UTR,intron-Distal3.904597.93263HepG2AKAP1
chr191871752818717603-5'-UTR,intron-Distal5.17294400.00000HepG2DDX3X
chr191871747018717602-5'-UTR,intron-Distal3.8633128.78044HepG2PCBP1
chr191871747318717607-5'-UTR,intron-Distal3.1477620.28781HepG2FTO
chr191871746518717528-5'-UTR,CDS,intron-Distal5.67729400.00000HepG2DDX3X
chr191871744618717544-5'-UTR,CDS,intron-Distal3.2554425.92064HepG2RPS3
chr191871754418717604-5'-UTR,intron-Distal4.0573127.54989HepG2RPS3
chr191870487518704885-CDS,intron-Distal3.3105410.46226HepG2LARP4
chr191870487718704919-CDS,intron-Distal,intron-Proximal3.0184211.59030HepG2SND1
chr191870969018709710-CDS,intron-Distal3.6204712.92533HepG2RPS3
chr191870491018705011-CDS,intron-Distal,intron-Proximal3.006415.90312HepG2EFTUD2
chr191870783318707860-CDS,intron-Distal,intron-Proximal3.7936025.16182HepG2RPS3
chr191870489118704959-CDS,intron-Distal,intron-Proximal3.193514.93258HepG2AQR
chr191870776918707833-CDS,intron-Distal4.7223169.77997HepG2RPS3
chr191870437918704391-CDS,intron-Distal3.7289118.52466HepG2LARP4
chr191870961618709662-CDS,intron-Distal3.4506421.52524HepG2RPS3
chr191870776418707818-CDS,intron-Distal3.4441210.48738HepG2SND1
chr191871739118717415-CDS,intron-Distal5.06669400.00000HepG2DDX3X
chr191871057918710622-CDS,intron-Distal3.7933018.60450HepG2RPS3
chr191871745418717465-CDS,intron-Distal4.7156186.09349HepG2DDX3X
chr191871735018717391-CDS,intron-Distal4.91644400.00000HepG2DDX3X
chr191870518218705225-CDS,intron-Distal3.2578312.14082HepG2RPS3
chr191871044818710503-CDS,intron-Distal,intron-Proximal5.1422235.11123HepG2RPS3
chr191871735318717410-CDS,intron-Distal3.2730630.99208HepG2RPS3
chr191870511918705166-CDS,intron-Distal,intron-Proximal5.1708819.76151HepG2SND1
chr191870516618705242-CDS,intron-Distal,intron-Proximal4.1615921.62164HepG2SND1
chr191871741518717434-CDS,intron-Distal4.82544400.00000HepG2DDX3X
chr191871039518710405-CDS,intron-Distal4.3161226.65702HepG2DDX3X
chr191871055918710616-CDS,intron-Distal3.7566050.69680HepG2DDX3X
chr191870781818707860-CDS,intron-Distal,intron-Proximal3.3882813.79637HepG2SND1
chr191870507418705118-CDS,intron-Distal,intron-Proximal3.9361218.26310HepG2SND1
chr191870437818704434-CDS,intron-Distal3.162696.82235HepG2AKAP1
chr191870969718709711-CDS,intron-Distal3.418044.57337HepG2SND1
chr191871064918710656-CDS,intron-Distal3.8038438.90087HepG2DDX3X
chr191871038618710438-CDS,intron-Distal,intron-Proximal3.0510911.35317HepG2SND1
chr191871743418717454-CDS,intron-Distal4.72985400.00000HepG2DDX3X
chr191870745818707513-CDS,intron-Distal,intron-Proximal3.1583316.96206HepG2LARP4
chr191870754618707595-CDS,intron-Distal3.4892925.60744HepG2RPS3
chr191871050318710539-CDS,intron-Distal,intron-Proximal4.2415513.35431HepG2RPS3
chr191870525718705323-intron-Distal,intron-Proximal3.729053.96535HepG2AQR
chr191871700918717064-intron-Distal3.288835.01757HepG2RBFOX2
chr191870450218704592-intron-Distal5.2064016.56087HepG2UPF1
chr191871723318717306-intron-Distal3.525004.81289HepG2RBM22
chr191871659118716626-intron-Distal3.898416.36044HepG2CSTF2T
chr191871703518717103-intron-Distal4.2394311.16670HepG2CSTF2T
chr191871682318716869-intron-Distal4.378914.93963HepG2XRN2
chr191870944118709536-intron-Distal,intron-Proximal4.557256.05374HepG2SF3B4
chr191871066018710722-intron-Distal,intron-Proximal5.113089.00594HepG2SF3B4
chr191871581018715884-intron-Distal4.814547.94475HepG2CSTF2
chr191870553418705621-intron-Distal3.375783.59803HepG2PTBP1
chr191870789318707979-intron-Distal,intron-Proximal3.781985.98968HepG2SF3B4
chr191871032818710355-intron-Distal,intron-Proximal3.339616.34676HepG2PRPF8
chr191870495918705049-intron-Distal,intron-Proximal3.8367711.43177HepG2AQR
chr191871663318716693-intron-Distal3.4657410.54269HepG2CSTF2T
chr191871610518716173-intron-Distal5.6505912.55897HepG2CSTF2T
chr191870055518700623-intron-Distal3.258483.49516HepG2CSTF2T
chr191871649218716562-intron-Distal3.257789.25952HepG2CSTF2T
chr191870561218705743-intron-Distal3.369916.47624HepG2PCBP2
chr191871478718714828-intron-Distal3.960967.72301HepG2CSTF2T
chr191870889518708945-intron-Distal4.691567.21143HepG2EFTUD2
chr191871510318715163-intron-Distal3.302097.11670HepG2CSTF2T
chr191871693918717024-intron-Distal4.9156312.80605HepG2CSTF2T
chr191870454618704560-intron-Distal3.885745.93237HepG2DDX55
chr191871721918717274-intron-Distal3.707124.98844HepG2FAM120A
chr191870954518709575-intron-Distal,intron-Proximal4.351515.05356HepG2PRPF8
chr191871485218714938-intron-Distal4.372478.28918HepG2CSTF2T
chr191871615318716181-intron-Distal4.071483.42782HepG2NKRF
chr191870478918704838-intron-Distal,intron-Proximal5.580366.82887HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CRLF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CRLF1 is not available on ENCORE database.

  • 91 RBPs can affect the levels of CRLF1.  








The Knockdown/knockout RNA-Seq assay for CRLF1 is not available on ENCORE database.





91 RBPs can affect the gene expression of CRLF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CRLF1ENSG00000006016.61222.815805287.16830-2.1123011.8193010.09640HepG2ABCF1
CRLF1ENSG00000006016.66113.974604984.025200.294706.458205.60900HepG2ACO1
CRLF1ENSG00000006016.61130.019102960.41170-1.3895024.0030022.51720HepG2BOP1
CRLF1ENSG00000006016.61371.310903359.51720-1.2927015.4057013.84300HepG2CALR
CRLF1ENSG00000006016.62078.034104982.47120-1.2616098.9423096.40930HepG2CKAP4
CRLF1ENSG00000006016.65249.523002915.141500.848505.027303.99110HepG2CNOT7
CRLF1ENSG00000006016.63464.504402826.943300.293303.143002.05720HepG2YBX3
CRLF1ENSG00000006016.61164.399702738.04210-1.233603.044701.59740HepG2CSTF2T
CRLF1ENSG00000006016.610933.001304541.649701.2673050.7556048.71470HepG2CELF1
CRLF1ENSG00000006016.66343.743804882.937600.377503.002902.23530HepG2DAZAP1
CRLF1ENSG00000006016.62146.886604609.29280-1.1023068.8744066.23720HepG2DDX19B
CRLF1ENSG00000006016.61500.197402941.74000-0.971503.075802.36330HepG2DDX21
CRLF1ENSG00000006016.6995.144302883.65390-1.534905.105103.85690HepG2DDX24
CRLF1ENSG00000006016.6642.526203364.51570-2.388604.783103.15280HepG2DDX27
CRLF1ENSG00000006016.65542.384303163.022300.809104.613002.91100HepG2DDX52
CRLF1ENSG00000006016.61383.123603866.88780-1.4832041.7795038.98080HepG2DDX5
CRLF1ENSG00000006016.615092.168503329.615602.1803018.6176017.20810HepG2DDX6
CRLF1ENSG00000006016.61772.298302677.32660-0.595208.549606.92430HepG2DHX30
CRLF1ENSG00000006016.6924.066704768.23980-2.36740215.63160212.62230HepG2DKC1
CRLF1ENSG00000006016.63613.184302775.886000.380202.107401.48530HepG2DNAJC21
CRLF1ENSG00000006016.61304.198402713.07600-1.056802.584001.51880HepG2AGO1
CRLF1ENSG00000006016.65664.919403198.158400.824702.343601.79530HepG2EIF2S1
CRLF1ENSG00000006016.61521.269802781.29040-0.870502.529601.49710HepG2EIF3G
CRLF1ENSG00000006016.6884.484803533.04370-1.998004.413003.60930HepG2EIF4A3
CRLF1ENSG00000006016.62208.120904817.70610-1.1255057.6614054.87910HepG2EIF4G1
CRLF1ENSG00000006016.66461.754104614.984400.485506.259105.05670HepG2EIF4G2
CRLF1ENSG00000006016.61665.265704578.35660-1.459109.723607.86890HepG2ESF1
CRLF1ENSG00000006016.61681.857204869.86520-1.5338060.4198057.24860HepG2EWSR1
CRLF1ENSG00000006016.64355.617102737.904600.669702.836001.65260HepG2FAM120A
CRLF1ENSG00000006016.61437.774802722.57140-0.921104.768103.44290HepG2FTO
CRLF1ENSG00000006016.62494.630403325.77900-0.414901.995201.31910HepG2FUBP3
CRLF1ENSG00000006016.610014.681603568.618601.4886013.8794012.45020HepG2FXR1
CRLF1ENSG00000006016.64989.988703308.352000.592801.864401.31260HepG2G3BP1
CRLF1ENSG00000006016.65041.450602806.411600.845004.379503.09060HepG2GNB2L1
CRLF1ENSG00000006016.6515.743103080.52340-2.5785057.3285054.87300HepG2GPKOW
CRLF1ENSG00000006016.67941.172704758.031700.738909.135107.49340HepG2HDGF
CRLF1ENSG00000006016.63988.159702469.154300.691602.690201.34310HepG2HNRNPA0
CRLF1ENSG00000006016.6655.501102802.47910-2.0960081.3225078.88440HepG2HNRNPA1
CRLF1ENSG00000006016.62524.398504367.14760-0.7908030.6637028.69640HepG2HNRNPF
CRLF1ENSG00000006016.66172.434304447.845600.4726010.712809.46490HepG2HNRNPL
CRLF1ENSG00000006016.6763.183602939.82180-1.9456037.1965035.30470HepG2HNRNPLL
CRLF1ENSG00000006016.67322.410703681.647700.9919020.9561018.79440HepG2HNRNPM
CRLF1ENSG00000006016.61466.553104300.36640-1.5520060.1739057.60280HepG2IGF2BP1
CRLF1ENSG00000006016.65438.599304555.731100.255505.632204.19190HepG2KIF1C
CRLF1ENSG00000006016.64856.285702751.051100.819803.944402.58260HepG2LARP7
CRLF1ENSG00000006016.65641.557103589.223700.652301.861401.33860HepG2MATR3
CRLF1ENSG00000006016.66093.827104318.029200.496903.441702.54080HepG2MSI2
CRLF1ENSG00000006016.66363.249603673.250900.792603.056502.39290HepG2NCBP2
CRLF1ENSG00000006016.66028.123404841.935000.316002.578901.84330HepG2NOL12
CRLF1ENSG00000006016.6565.91740318.710500.828205.205803.26470HepG2NOLC1
CRLF1ENSG00000006016.61083.300102606.88700-1.2669021.6277019.81300HepG2NSUN2
CRLF1ENSG00000006016.61438.980603386.27750-1.2347024.1229022.62850HepG2PCBP1
CRLF1ENSG00000006016.64518.701802761.934800.7101014.6512013.03040HepG2PPIL4
CRLF1ENSG00000006016.61353.371804326.28990-1.6766060.6345058.05950HepG2PRPF4
CRLF1ENSG00000006016.64270.375503445.914900.309403.905903.28090HepG2PTBP1
CRLF1ENSG00000006016.68470.443904906.789600.7876055.2251053.28140HepG2PUM1
CRLF1ENSG00000006016.61396.307305076.48410-1.86220149.95310146.95360HepG2PUS1
CRLF1ENSG00000006016.65414.287403731.476200.536905.494604.65860HepG2QKI
CRLF1ENSG00000006016.63623.942105567.39840-0.619406.183304.96430HepG2RBM15
CRLF1ENSG00000006016.63433.629008092.77880-1.2369021.3496020.18360HepG2RBM22
CRLF1ENSG00000006016.64458.149302694.064800.726602.436601.44370HepG2RCC2
CRLF1ENSG00000006016.6613.437204704.89620-2.93920161.30030158.02350HepG2RPLP0
CRLF1ENSG00000006016.61388.306903196.02910-1.203007.979806.79370HepG2SF3A3
CRLF1ENSG00000006016.6415.962302909.70540-2.8063063.8642061.21390HepG2SF3B1
CRLF1ENSG00000006016.62889.753301271.530901.184303.280201.68130HepG2SFPQ
CRLF1ENSG00000006016.66264.883803215.942300.9619073.1236070.72880HepG2SMN1
CRLF1ENSG00000006016.63339.938401171.309301.511607.200404.87140HepG2SNRNP200
CRLF1ENSG00000006016.61850.976003237.60680-0.806607.160205.89760HepG2SNRNP70
CRLF1ENSG00000006016.62841.121309140.19600-1.6858035.0416033.78510HepG2SRFBP1
CRLF1ENSG00000006016.61631.308703744.43580-1.1987017.5229016.54780HepG2SRSF1
CRLF1ENSG00000006016.61843.994503131.24380-0.763908.358206.54120HepG2SRSF3
CRLF1ENSG00000006016.67897.507604563.900300.7910037.0551035.13030HepG2SRSF5
CRLF1ENSG00000006016.61762.512004290.67250-1.2836074.6379072.23660HepG2SRSF7
CRLF1ENSG00000006016.62205.926303046.45610-0.465705.209204.49400HepG2SRSF9
CRLF1ENSG00000006016.6340.900907935.33040-4.54090125.94680123.89280HepG2SSB
CRLF1ENSG00000006016.61747.105803563.39960-1.028305.368203.70020HepG2STAU1
CRLF1ENSG00000006016.68223.694005190.262000.6639034.9884033.20510HepG2SUCLG1
CRLF1ENSG00000006016.61497.485703602.58310-1.266509.711008.04370HepG2SUPT6H
CRLF1ENSG00000006016.6999.752103580.33440-1.840503.930303.14580HepG2SUPV3L1
CRLF1ENSG00000006016.61245.701603366.15450-1.4341017.3969016.16440HepG2TAF15
CRLF1ENSG00000006016.61675.726503599.05810-1.102802.966801.86200HepG2TBRG4
CRLF1ENSG00000006016.65064.379103092.496600.711503.125002.24180HepG2TIA1
CRLF1ENSG00000006016.61109.843303009.00960-1.4389057.0512055.32850HepG2TIAL1
CRLF1ENSG00000006016.66889.525204515.908500.609302.225801.44810HepG2TUFM
CRLF1ENSG00000006016.62155.141304565.15020-1.082907.188906.18360HepG2U2AF1
CRLF1ENSG00000006016.64646.065902834.396500.712909.056507.91640HepG2UPF1
CRLF1ENSG00000006016.61442.418502736.48720-0.9238021.0477019.62650HepG2UTP3
CRLF1ENSG00000006016.64451.651902625.711500.761503.193902.00570HepG2XPO5
CRLF1ENSG00000006016.61513.771203524.47600-1.219302.550101.85270HepG2XRN2
CRLF1ENSG00000006016.62343.328304269.31870-0.8654019.8261018.31880HepG2ZC3H8
CRLF1ENSG00000006016.61429.336303117.28320-1.1249033.5941032.23210HepG2ZNF622
CRLF1ENSG00000006016.63.7686020.11010-2.415802.769002.16370K562FXR1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CRLF1 is not available on ENCORE database.





12 RBPs can affect the splicing of CRLF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECRLF1ENSG00000006016.6chr19-187044851870468218704046187043891870487418704944-0.083000.000630.05801excludedHepG2PRPF8
SECRLF1ENSG00000006016.6chr19-187044851870468218704046187043891870487418704944-0.183000.000210.05177excludedHepG2ILF3
SECRLF1ENSG00000006016.6chr19-1871271618712815187105091871065618717351187176600.190000.000000.00334includedHepG2HLTF
SECRLF1ENSG00000006016.6chr19-187127161871281518710509187106561871735118717660-0.084000.000040.00500excludedHepG2HNRNPL
SECRLF1ENSG00000006016.6chr19-187044851870468218704046187043891870487418704944-0.200000.000020.01300excludedHepG2XPO5
SECRLF1ENSG00000006016.6chr19-187044851870468218704046187043891870487418704922-0.086000.001290.09836excludedHepG2SUPV3L1
SECRLF1ENSG00000006016.6chr19-187127161871281518710509187106561871735118717660-0.085000.000060.02462excludedHepG2NOL12
SECRLF1ENSG00000006016.6chr19-187127161871281518710509187106561871735118717660-0.074000.000660.03087excludedHepG2HNRNPU
SECRLF1ENSG00000006016.6chr19-187127161871281518710509187106561871735118717660-0.067000.001020.03926excludedHepG2HNRNPC
A3SSCRLF1ENSG00000006016.6chr19-1870897318709147187089731870905418709241187094030.486000.000220.02454longerHepG2RBM22
A3SSCRLF1ENSG00000006016.6chr19-187048741870496018704874187049171870505618705117-0.109000.000170.06104shorterHepG2HNRNPC
RICRLF1ENSG00000006016.6chr19-187048741870511718704874187049171870505618705117-0.079000.000350.07417excludedHepG2XRCC6
RICRLF1ENSG00000006016.6chr19-1870487418705117187048741870492218705056187051170.850000.000000.00111includedHepG2SUPV3L1
RICRLF1ENSG00000006016.6chr19-187048741870511718704874187049171870505618705117-0.096000.000000.00296excludedHepG2TRA2A
RICRLF1ENSG00000006016.6chr19-187048741870511718704874187049171870505618705117-0.080000.000150.01075excludedHepG2HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CRLF1 is not avaliable on ENCORE database.