PABPC3

General Information

Gene Name : PABPC3
Gene ID : ENSG00000151846.8
Essential Gene : No

Functions

Novel RBP

Localization(RBPImage: PABPC3)

Nuclei
Nucleoplasm
Speckles
Cytoplasm
Cytosolic

Domains (AlphaFold: PABPC3)

RRM

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PABPC3	ENSG00000151846.8	0.55	0.59	0.57	ENCSR000AEF
HepG2	PABPC3	ENSG00000151846.8	0.17	0.43	0.30	ENCSR985KAT
K562	PABPC3	ENSG00000151846.8	0.46	0.54	0.50	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
RNA Bind-n-Seq	RBNS: PABPC3	ENCSR051WAN	PABPC3	cell-free sample	Released

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
PABPC3	K562	shRNA	BGKLV32-49,BGKLV32-50	BGKLV32-1,BGKLV32-2	0.0,0.0	NotSatisfied	ENCODE3
PABPC3	K562	shRNA	BGKLV38-47,BGKLV38-48	BGKLV38-1,BGKLV38-2	no band on the position,no band on the position	NotSatisfied	ENCODE3
PABPC3	K562	shRNA	BGKLV38-49,BGKLV38-50	BGKLV38-1,BGKLV38-2	no band on the position,no band on the position	NotSatisfied	ENCODE3
PABPC3	K562	shRNA	BGKLV38-51,BGKLV38-52	BGKLV38-1,BGKLV38-2	no band on the position,no band on the position	NotSatisfied	ENCODE3
PABPC3	K562	shRNA	BGKLV38-53,BGKLV38-54	BGKLV38-1,BGKLV38-2		NotSatisfied	ENCODE3
PABPC3	HepG2	shRNA	BGHLV22-35,BGHLV22-36	BGHLV22-1,BGHLV22-2	redo transfection,redo transfection	NotSatisfied	ENCODE3
PABPC3	HepG2	shRNA	BGHLV37-33,BGHLV37-34	BGHLV37-1,BGHLV37-2	no band,	NotSatisfied	ENCODE3
PABPC3	HepG2	shRNA	BGHLV37-35,BGHLV37-36	BGHLV37-1,BGHLV37-2	no band,	NotSatisfied	ENCODE3

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
PABPC3	PABPC3		Released	ENCODE4

Localization Image in HepG2

PABPC3: Click to RBP Image Database

Nuclei

Nucleoplasm

Speckles

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary

RNA Targets

eCLIP assay for PABPC3 is not avaliable on ENCORE database.

The binding motifs of PABPC3

Proteins bound to RNA

NO known proteins bind on PABPC3 RNA with finished eCLIP experiments on ENCORE database.

eCLIP assay for PABPC3 is not avaliable on ENCORE database.

NO known proteins are bound to PABPC3 RNA with finished eCLIP experiments on ENCORE database.

eCLIP assay for PABPC3 is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for PABPC3 is not available on ENCORE database.
17 RBPs can affect the levels of PABPC3.

The Knockdown/knockout RNA-Seq assay for PABPC3 is not available on ENCORE database.

17 RBPs can affect the gene expression of PABPC3 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PABPC3	ENSG00000151846.7	2.80940	20.71760	-2.88250	3.32890	2.35030	HepG2	PABPC1
PABPC3	ENSG00000151846.7	15.48130	55.24600	-1.83530	4.58070	3.46910	K562	FIP1L1
PABPC3	ENSG00000151846.7	9.18490	40.87450	-2.15390	4.27290	3.21010	K562	FMR1
PABPC3	ENSG00000151846.7	8.23140	34.64580	-2.07350	3.59560	2.54160	K562	FTO
PABPC3	ENSG00000151846.7	6.53900	38.35160	-2.55210	5.00040	3.93690	K562	GPKOW
PABPC3	ENSG00000151846.7	14.24260	45.44030	-1.67380	3.12990	2.13490	K562	HNRNPM
PABPC3	ENSG00000151846.7	35.86350	74.90220	-1.06250	2.68910	1.90490	K562	HSPD1
PABPC3	ENSG00000151846.7	87.29430	44.44910	0.97360	2.77870	1.95120	K562	KIF1C
PABPC3	ENSG00000151846.7	9.82640	32.75000	-1.73680	2.40060	1.53890	K562	KRR1
PABPC3	ENSG00000151846.7	95.64270	49.79350	0.94160	2.59620	1.71980	K562	MBNL1
PABPC3	ENSG00000151846.7	9.84120	37.43590	-1.92750	3.51940	2.52550	K562	METAP2
PABPC3	ENSG00000151846.7	84.07560	34.90120	1.26830	3.28700	2.31000	K562	NAA15
PABPC3	ENSG00000151846.7	3.29930	47.66810	-3.85280	8.73070	6.54170	K562	PABPC1
PABPC3	ENSG00000151846.7	12.94190	44.92980	-1.79560	2.69730	1.72220	K562	PABPN1
PABPC3	ENSG00000151846.7	16.35520	62.71460	-1.93910	5.89590	4.62320	K562	PPIG
PABPC3	ENSG00000151846.7	8.63470	36.47730	-2.07880	3.41900	2.33480	K562	SF3B1
PABPC3	ENSG00000151846.7	26.53650	72.48670	-1.44970	4.08600	2.40850	K562	SSRP1
PABPC3	ENSG00000151846.7	22.21350	66.29870	-1.57750	4.28060	2.66130	K562	STAU1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PABPC3

General Information

Functions

Localization(RBPImage: PABPC3)

Domains (AlphaFold: PABPC3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PABPC3 is not avaliable on ENCORE database.

NO known proteins are bound to PABPC3 RNA with finished eCLIP experiments on ENCORE database.

eCLIP assay for PABPC3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PABPC3 is not available on ENCORE database.

17 RBPs can affect the gene expression of PABPC3 :

The Knockdown/knockout RNA-Seq assay for PABPC3 is not available on ENCORE database.

No RBPs affect the alternative splcing events of PABPC3 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for PABPC3 is not avaliable on ENCORE database.