RPL18

General Information

Gene Name : RPL18
Gene ID : ENSG00000063177.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: RPL18)

Not Available

Antibody Validation

Bethyl Labs: A305-340A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RPL18	ENSG00000063177.12	1080.31	1454.00	1267.15	ENCSR000AEF
HepG2	RPL18	ENSG00000063177.12	1563.01	887.10	1225.06	ENCSR985KAT
K562	RPL18	ENSG00000063177.12	1634.43	1111.69	1373.06	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	RPL18-BGHcLV22-HepG2	ENCSR468LEL	RPL18	HepG2	Released		ENCSR704VPL	CRISPR	KD% = 90.1,92.7

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RPL18	ENCAB569OQM	A305-340A	1				BGHcLV22-45, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
RPL18	K562	CRISPR			BGKcLV21-37,BGKcLV21-38	BGKcLV21-1,BGKcLV21-2	32.1,34.1	NotSatisfied	ENCODE4
RPL18	K562	CRISPR			BGKcLV23-57,BGKcLV23-58	BGKcLV23-1,BGKcLV23-2	0.0,0.0	NotSatisfied	ENCODE4
RPL18	HepG2	CRISPR			BGHcLV22-43,BGHcLV22-44	BGHcLV22-1,BGHcLV22-2		NotSatisfied	ENCODE4
RPL18	HepG2	CRISPR	ENCSR468LEL	ENCSR704VPL	RPL18-BGHcLV22-45,RPL18-BGHcLV22-46	NT-BGHcLV22-1,NT-BGHcLV22-2	90.1,92.7	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RPL18	Product_ID: A305-340A Lot_ID: 1 Source: Bethyl Labs Target Name: RPL18-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RPL18 is not avaliable on ENCORE database.

Proteins bound to RNA

RPL18 RNA is bound by 28 proteins.

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eCLIP assay for RPL18 is not avaliable on ENCORE database.

28 proteins are bound to RPL18 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	49120010	49120040	-	3'-UTR,CDS,intron-Distal	8.45676	400.00000	K562	LIN28B
chr19	49119991	49120010	-	3'-UTR,CDS,intron-Distal	6.79491	400.00000	K562	LIN28B
chr19	49119394	49119433	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.36761	400.00000	K562	PABPC4
chr19	49119349	49119394	-	3'-UTR,CDS,intron-Distal	3.65168	400.00000	K562	PABPC4
chr19	49119354	49119360	-	3'-UTR,CDS,intron-Distal	3.45870	400.00000	K562	YBX3
chr19	49119433	49119445	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.28310	400.00000	K562	PABPC4
chr19	49119134	49119177	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.03632	400.00000	K562	PABPC4
chr19	49119348	49119353	-	3'-UTR,CDS,intron-Distal	3.42488	400.00000	K562	YBX3
chr19	49119360	49119392	-	3'-UTR,CDS,intron-Distal	3.73310	400.00000	K562	YBX3
chr19	49119401	49119438	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.50178	400.00000	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 167 entries

eCLIP assay for RPL18 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for RPL18 is not available on ENCORE database.
118 RBPs can affect the levels of RPL18.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RPL18 is not available on ENCORE database.

118 RBPs can affect the gene expression of RPL18 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RPL18	ENSG00000063177.8	4472.86150	14268.10110	-1.67350	190.99460	188.72200	HepG2	SRSF1
RPL18	ENSG00000063177.8	4588.26640	13129.80790	-1.51680	130.15310	127.85080	HepG2	PTBP1
RPL18	ENSG00000063177.8	4835.60960	11607.99100	-1.26330	104.17990	101.84360	HepG2	SRSF9
RPL18	ENSG00000063177.8	6941.63470	14612.04320	-1.07380	72.23560	70.40540	HepG2	NELFE
RPL18	ENSG00000063177.8	6479.46940	14219.46390	-1.13390	54.29340	52.20420	HepG2	QKI
RPL18	ENSG00000063177.8	7284.99600	13669.45270	-0.90800	53.33440	51.39170	HepG2	SF3B4
RPL18	ENSG00000063177.8	6185.60190	12825.14700	-1.05200	51.30920	49.28880	HepG2	TAF15
RPL18	ENSG00000063177.8	20293.63310	10957.05200	0.88910	42.48880	40.30820	K562	AGGF1
RPL18	ENSG00000063177.8	7981.22540	13609.44520	-0.76990	39.34260	37.54680	HepG2	RECQL
RPL18	ENSG00000063177.8	7642.45080	12903.31000	-0.75560	36.38110	34.61400	HepG2	PCBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 138 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RPL18 is not available on ENCORE database.

18 RBPs can affect the splicing of RPL18 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
A3SS	RPL18	ENSG00000063177.8	chr19	-	49118584	49118781			49118584	49118704	49119133	49119254	0.05300	0.00000	longer	K562	AQR
RI	RPL18	ENSG00000063177.8	chr19	-	49118587	49119203			49118587	49118704	49119133	49119203	0.05400	0.00000	included	K562	PUS1
RI	RPL18	ENSG00000063177.8	chr19	-	49118587	49119203			49118587	49118704	49119133	49119203	0.06700	0.00000	included	K562	AQR
RI	RPL18	ENSG00000063177.8	chr19	-	49118622	49119203			49118622	49118738	49119133	49119203	-0.46200	0.00000	excluded	K562	AQR
MXE	RPL18	ENSG00000063177.8	chr19	-	49119335	49119459	49119982	49120081	49119133	49119203	49120572	49120680	-0.08100	0.00062	2included	K562	MATR3
MXE	RPL18	ENSG00000063177.8	chr19	-	49119982	49120081	49120572	49120680	49119335	49119459	49121047	49121134	0.06400	0.00001	1included	K562	U2AF1
MXE	RPL18	ENSG00000063177.8	chr19	-	49119335	49119459	49119982	49120081	49119133	49119203	49120572	49120680	-0.23400	0.00000	2included	K562	XRN2
MXE	RPL18	ENSG00000063177.8	chr19	-	49119335	49119459	49119982	49120081	49119133	49119203	49120572	49120680	-0.15000	0.00000	2included	HepG2	NIP7
MXE	RPL18	ENSG00000063177.8	chr19	-	49119335	49119459	49119982	49120081	49119133	49119203	49120572	49120680	-0.18100	0.00000	2included	K562	NONO
MXE	RPL18	ENSG00000063177.8	chr19	-	49119982	49120081	49120572	49120680	49119335	49119459	49121047	49121134	-0.11100	0.00003	2included	K562	TARDBP

Showing 1 to 10 of 25 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RPL18

General Information

Functions

Localization

Domains (AlphaFold: RPL18)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RPL18 is not avaliable on ENCORE database.

28 proteins are bound to RPL18 RNA:

eCLIP assay for RPL18 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RPL18 is not available on ENCORE database.

118 RBPs can affect the gene expression of RPL18 :

The Knockdown/knockout RNA-Seq assay for RPL18 is not available on ENCORE database.

18 RBPs can affect the splicing of RPL18 :

The Knockdown/knockout RNA-Seq assay for RPL18 is not avaliable on ENCORE database.