NEDD4

General Information

Gene Name : NEDD4
Gene ID : ENSG00000069869.16
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: NEDD4)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	NEDD4	ENSG00000069869.16	4.51	4.03	4.27	ENCSR000AEF
HepG2	NEDD4	ENSG00000069869.16	6.30	12.99	9.64	ENCSR985KAT
K562	NEDD4	ENSG00000069869.16	13.53	15.94	14.73	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
NEDD4	HepG2	CRISPR			BGHcLV41-87,BGHcLV41-88	BGHcLV41-1,BGHcLV41-2	0.0,0.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for NEDD4 is not avaliable on ENCORE database.

Proteins bound to RNA

NEDD4 RNA is bound by 13 proteins.

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eCLIP assay for NEDD4 is not avaliable on ENCORE database.

13 proteins are bound to NEDD4 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	56145659	56145677	-	intron-Distal	5.96448	16.48436	HepG2	SF3B4
chr15	56145679	56145688	-	intron-Distal	5.96448	16.48436	HepG2	SF3B4
chr15	56155110	56155203	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.24259	7.04013	HepG2	BCLAF1
chr15	56145658	56145688	-	intron-Distal	6.03807	6.37906	K562	DDX42
chr15	56214177	56214247	-	intron-Distal	3.82013	6.19377	K562	KHSRP
chr15	56134129	56134312	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.53419	5.52031	HepG2	GRWD1
chr15	56155205	56155276	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.60313	5.24929	K562	ZNF622
chr15	56214247	56214324	-	intron-Distal	3.73148	5.14864	K562	KHSRP
chr15	56176375	56176471	-	intron-Distal	4.34602	4.78128	HepG2	SUGP2
chr15	56285707	56285821	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.21372	4.52089	HepG2	NCBP2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 26 entries

eCLIP assay for NEDD4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for NEDD4 is not available on ENCORE database.
93 RBPs can affect the levels of NEDD4.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for NEDD4 is not available on ENCORE database.

93 RBPs can affect the gene expression of NEDD4 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
NEDD4	ENSG00000069869.11	479.26830	1061.11990	-1.14670	29.52690	27.90510	HepG2	PCBP1
NEDD4	ENSG00000069869.11	1634.09100	795.27890	1.03890	28.88900	27.00720	K562	EIF2S2
NEDD4	ENSG00000069869.11	1684.95040	654.08490	1.36510	23.41520	21.79130	HepG2	SUPV3L1
NEDD4	ENSG00000069869.11	1536.42550	894.26500	0.78070	22.26960	20.91840	HepG2	PUM1
NEDD4	ENSG00000069869.11	966.31020	1929.62650	-0.99780	20.02170	17.94170	K562	AKAP8L
NEDD4	ENSG00000069869.11	1403.46880	867.46990	0.69400	17.94720	16.85600	HepG2	ZNF622
NEDD4	ENSG00000069869.11	2322.75640	1210.86950	0.93970	17.30570	15.44060	K562	HSPD1
NEDD4	ENSG00000069869.11	1004.63410	1913.96820	-0.92990	12.47840	11.37150	K562	PUS1
NEDD4	ENSG00000069869.11	1331.97400	711.88390	0.90380	12.51010	11.14130	HepG2	U2AF1
NEDD4	ENSG00000069869.11	652.07940	1186.48110	-0.86360	11.64550	10.56280	K562	AQR
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 101 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for NEDD4 is not available on ENCORE database.

8 RBPs can affect the splicing of NEDD4 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.29100	0.00000	0.00001	excluded	K562	PUS1
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.36800	0.00001	0.00030	excluded	K562	SF3B4
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.06700	0.00006	0.00888	excluded	K562	HNRNPUL1
A5SS	NEDD4	ENSG00000069869.11	chr15	-	56244779	56244943	56244851	56244943	56243708	56243787	-0.64700	0.00014	0.00781	shorter	HepG2	U2AF2
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.15800	0.00022	0.01076	excluded	K562	UTP18
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.27000	0.00041	0.00958	excluded	K562	U2AF2
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.10700	0.00064	0.01954	excluded	K562	AGGF1
A3SS	NEDD4	ENSG00000069869.11	chr15	-	56126424	56126484	56126424	56126460	56129986	56130047	0.05500	0.00074	0.02074	longer	HepG2	U2AF2
SE	NEDD4	ENSG00000069869.11	chr15	-	56126424	56126484	56126235	56126343	56129986	56130047	-0.11100	0.00372	0.03650	excluded	K562	AQR
SE	NEDD4	ENSG00000069869.11	chr15	-	56139166	56139232	56134131	56134361	56140569	56140628	-0.11700	0.00426	0.08120	excluded	K562	RBM15

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

NEDD4

General Information

Functions

Localization

Domains (AlphaFold: NEDD4)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for NEDD4 is not avaliable on ENCORE database.

13 proteins are bound to NEDD4 RNA:

eCLIP assay for NEDD4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for NEDD4 is not available on ENCORE database.

93 RBPs can affect the gene expression of NEDD4 :

The Knockdown/knockout RNA-Seq assay for NEDD4 is not available on ENCORE database.

8 RBPs can affect the splicing of NEDD4 :

The Knockdown/knockout RNA-Seq assay for NEDD4 is not avaliable on ENCORE database.