SNRNP70

General Information

Gene Name : SNRNP70
Gene ID : ENSG00000104852.14
Essential Gene : Yes

Functions

Spliceosome

Localization

Not Available

Domains (AlphaFold: SNRNP70)

RRM

Antibody Validation

Santa Cruz Biotech: sc-9571

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SNRNP70	ENSG00000104852.14	64.54	76.34	70.44	ENCSR000AEF
HepG2	SNRNP70	ENSG00000104852.14	166.01	98.62	132.31	ENCSR985KAT
K562	SNRNP70	ENSG00000104852.14	135.74	96.32	116.03	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SNRNP70-BGHLV35-HepG2	ENCSR635BOO	SNRNP70	HepG2	Released		ENCSR264TUE	shRNA	KD% = 81.2,78.8

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SNRNP70	ENCAB649NDD	sc-9571	B2409		Released, ENCODE3	Released, ENCODE3	BGHLV35-45, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
SNRNP70	HepG2	shRNA	ENCSR635BOO	ENCSR264TUE	SNRNP70_BGHLV35-45,SNRNP70_BGHLV35-46	NT_BGHLV35-1,NT_BGHLV35-2	81.2,78.8	Released	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SNRNP70	Product_ID: sc-9571 Lot_ID: B2409 Source: Santa Cruz Biotech Target Name: SNRNP70-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SNRNP70 is not avaliable on ENCORE database.

Proteins bound to RNA

SNRNP70 RNA is bound by 65 proteins.

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eCLIP assay for SNRNP70 is not avaliable on ENCORE database.

65 proteins are bound to SNRNP70 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	49607839	49607900	+	3'-UTR,CDS,intron-Proximal	6.11111	400.00000	K562	SF3B4
chr19	49605976	49606048	+	3'-UTR,intron-Distal	4.38128	400.00000	HepG2	RBFOX2
chr19	49607790	49607819	+	intron-Distal,intron-Proximal	4.38258	400.00000	HepG2	SF3B4
chr19	49607474	49607542	+	intron-Distal	5.24122	400.00000	HepG2	RBFOX2
chr19	49607783	49607839	+	intron-Distal,intron-Proximal	5.82530	400.00000	K562	SF3B4
chr19	49607819	49607837	+	intron-Proximal	4.43604	400.00000	HepG2	SF3B4
chr19	49607836	49607888	+	intron-Proximal	7.00753	98.86308	K562	SMNDC1
chr19	49607841	49607882	+	intron-Proximal	4.42268	85.78683	HepG2	SF3B4
chr19	49607761	49607836	+	intron-Distal,intron-Proximal	5.48846	84.85827	K562	SMNDC1
chr19	49607644	49607664	+	intron-Distal	4.73623	84.74870	HepG2	PRPF4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 354 entries

eCLIP assay for SNRNP70 is not avaliable on ENCORE database.

Diffrential Expression

5,286 differentially expressed genes after Knockdown/Knockout SNRNP70 protein.

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110 RBPs can affect the levels of SNRNP70.

CanvasJS.com

5,286 differentially expressed genes after Knockdown/Knockout SNRNP70 protein :

Only display 100 entries as example. Please click "View All" button to see all 5,286 entries.

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ANLN	ENSG00000011426.6	953.95330	3689.37670	-1.95140	34.76180	32.06680	HepG2	SNRNP70
MGST1	ENSG00000008394.8	728.32530	2526.17760	-1.79430	28.35750	25.91580	HepG2	SNRNP70
BRCA1	ENSG00000012048.15	500.05330	1747.66410	-1.80530	26.36840	24.03750	HepG2	SNRNP70
NFIX	ENSG00000008441.12	345.49670	1187.58940	-1.78130	23.42280	21.22840	HepG2	SNRNP70
WIZ	ENSG00000011451.13	270.46460	916.51500	-1.76070	21.15070	19.06450	HepG2	SNRNP70
FYN	ENSG00000010810.13	316.22310	1033.08800	-1.70790	20.92460	18.85160	HepG2	SNRNP70
TFPI	ENSG00000003436.10	30612.09030	9056.51480	1.75700	17.95220	16.00730	HepG2	SNRNP70
RHBDD2	ENSG00000005486.12	1853.22630	513.40810	1.85180	15.28590	13.46480	HepG2	SNRNP70
DBF4	ENSG00000006634.3	443.92650	1152.16020	-1.37590	15.12100	13.31410	HepG2	SNRNP70
ARSD	ENSG00000006756.11	775.67750	233.85160	1.72980	14.68280	12.90320	HepG2	SNRNP70
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

110 RBPs can affect the gene expression of SNRNP70 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SNRNP70	ENSG00000104852.10	8824.78320	3470.49880	1.34630	41.43380	39.04810	HepG2	HNRNPK
SNRNP70	ENSG00000104852.10	3640.86880	2208.29830	0.72120	32.08670	30.10330	HepG2	DNAJC2
SNRNP70	ENSG00000104852.10	2961.39020	4615.14850	-0.64010	27.79690	26.18390	HepG2	CKAP4
SNRNP70	ENSG00000104852.10	5370.09760	2861.16560	0.90820	24.76060	22.63740	K562	SRSF1
SNRNP70	ENSG00000104852.10	9592.43370	5887.66890	0.70410	22.37290	20.61620	K562	RBM15
SNRNP70	ENSG00000104852.10	3447.74110	1548.63640	1.15460	22.59950	20.51860	HepG2	UCHL5
SNRNP70	ENSG00000104852.10	3900.91900	2485.24120	0.65030	21.53790	19.95680	HepG2	HNRNPU
SNRNP70	ENSG00000104852.10	7184.97310	3424.91820	1.06880	19.66510	17.96790	HepG2	G3BP1
SNRNP70	ENSG00000104852.10	1197.68650	4674.16110	-1.96450	18.21870	16.25910	HepG2	SNRNP70
SNRNP70	ENSG00000104852.10	9346.19010	5855.66930	0.67440	17.07880	15.79200	K562	AGGF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 128 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SNRNP70 is not available on ENCORE database.

76 RBPs can affect the splicing of SNRNP70 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.25800	0.00000	included	HepG2	G3BP1
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.23400	0.00000	included	K562	FTO
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.13300	0.00000	included	HepG2	RBM22
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.06800	0.00009	included	K562	XRN2
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.09700	0.00010	included	HepG2	IGF2BP1
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	-0.05800	0.00005	excluded	HepG2	U2AF1
SE	SNRNP70	ENSG00000104852.10	chr19	+	49589661	49589818	49588675	49588893	49593547	49593610	-0.08500	0.00000	excluded	HepG2	U2AF1
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.12000	0.00000	included	HepG2	DHX30
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.05500	0.00000	included	K562	UTP3
SE	SNRNP70	ENSG00000104852.10	chr19	+	49605370	49606844	49604646	49604728	49607890	49607992	0.34700	0.00000	included	K562	FMR1

Showing 1 to 10 of 106 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SNRNP70

General Information

Functions

Localization

Domains (AlphaFold: SNRNP70)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SNRNP70 is not avaliable on ENCORE database.

65 proteins are bound to SNRNP70 RNA:

eCLIP assay for SNRNP70 is not avaliable on ENCORE database.

Diffrential Expression

5,286 differentially expressed genes after Knockdown/Knockout SNRNP70 protein :

110 RBPs can affect the gene expression of SNRNP70 :

The Knockdown/knockout RNA-Seq assay for SNRNP70 is not available on ENCORE database.

76 RBPs can affect the splicing of SNRNP70 :

The Knockdown/knockout RNA-Seq assay for SNRNP70 is not avaliable on ENCORE database.