CCDC124

General Information

Gene Name : CCDC124
Gene ID : ENSG00000007080.10
Essential Gene : No

Functions

Novel RBP

Localization(RBPImage: CCDC124)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Cytoplasm
Cytosolic

Domains (AlphaFold: CCDC124)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

View validation images for all CCDC124 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CCDC124	ENSG00000007080.10	1.26	12.04	6.65	ENCSR000AEF
HepG2	CCDC124	ENSG00000007080.10	98.90	11.84	55.37	ENCSR985KAT
K562	CCDC124	ENSG00000007080.10	70.08	18.91	44.49	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CCDC124-BGKLV32-K562	ENCSR874ZLI	CCDC124	K562	Released		ENCSR143COQ	shRNA	KD% = 63.6,63.6

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CCDC124	ENCAB759HYT	A301-835A	1			Released, ENCODE4		BGKLV32-13, Released, ENCODE3
CCDC124	ENCAB733GNF	A301-834A	1			Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CCDC124	K562	shRNA	ENCSR874ZLI	ENCSR143COQ	CCDC124_BGKLV32-13,CCDC124_BGKLV32-14	NT_BGKLV32-1,NT_BGKLV32-2	63.6,63.6	Released	ENCODE3
CCDC124	HepG2	shRNA			BGHLV31-21,BGHLV31-22	BGHLV31-1,BGHLV31-2	30.7,44.9	NotSatisfied	ENCODE3
CCDC124	HepG2	CRISPR			BGHcLV12-11,BGHcLV12-12	BGHcLV12-1,BGHcLV12-2	0.0,0.0	NotSatisfied	ENCODE4
CCDC124	HepG2	CRISPR			BGHcLV12-13,BGHcLV12-14	BGHcLV12-1,BGHcLV12-2	0.0,0.0	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

CCDC124: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CCDC124	Product_ID: A301-834A Lot_ID: 1 Source: Bethyl Labs Target Name: CCDC124-human
CCDC124	Product_ID: A301-835A Lot_ID: 1 Source: Bethyl Labs Target Name: CCDC124-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CCDC124 is not avaliable on ENCORE database.

Proteins bound to RNA

CCDC124 RNA is bound by 9 proteins.

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eCLIP assay for CCDC124 is not avaliable on ENCORE database.

9 proteins are bound to CCDC124 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	18054729	18054771	+	3'-UTR	7.88940	23.93419	K562	PABPC4
chr19	18054463	18054585	+	3'-UTR,CDS	4.22557	16.81236	K562	PABPC4
chr19	18053484	18053550	+	CDS	4.26901	10.22171	K562	UCHL5
chr19	18054095	18054153	+	CDS	3.93904	9.71209	K562	UCHL5
chr19	18054650	18054729	+	3'-UTR	3.94576	9.16632	K562	PABPC4
chr19	18047225	18047303	+	5'-UTR,CDS	4.56523	8.63879	K562	UCHL5
chr19	18053512	18053594	+	CDS	3.49650	7.07280	K562	PUM1
chr19	18047325	18047375	+	CDS	3.39051	6.62505	K562	UCHL5
chr19	18054659	18054775	+	3'-UTR	3.95580	6.53456	HepG2	PCBP2
chr19	18047234	18047286	+	CDS	3.16086	5.74118	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 18 entries

eCLIP assay for CCDC124 is not avaliable on ENCORE database.

Diffrential Expression

2,111 differentially expressed genes after Knockdown/Knockout CCDC124 protein.

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125 RBPs can affect the levels of CCDC124.

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2,111 differentially expressed genes after Knockdown/Knockout CCDC124 protein :

Only display 100 entries as example. Please click "View All" button to see all 2,111 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CCDC124	ENSG00000007080.6	205.86350	1268.28790	-2.62310	75.57870	71.47550	K562	CCDC124
VIM	ENSG00000026025.9	21024.28650	10632.77060	0.98340	19.51700	16.57520	K562	CCDC124
TARBP1	ENSG00000059588.5	956.01670	1695.68060	-0.82680	16.40620	13.63540	K562	CCDC124
BOD1L1	ENSG00000038219.8	1920.53380	3065.58210	-0.67470	13.76670	11.18200	K562	CCDC124
CTSA	ENSG00000064601.12	1237.39760	733.04860	0.75520	11.95330	9.52220	K562	CCDC124
TMSB10	ENSG00000034510.4	8716.87260	5981.33990	0.54320	11.60690	9.20610	K562	CCDC124
TENM1	ENSG00000009694.9	1267.67870	2489.29490	-0.97350	11.45030	9.06720	K562	CCDC124
TFPI	ENSG00000003436.10	3719.45380	2389.26590	0.63840	11.04710	8.69970	K562	CCDC124
IGF1	ENSG00000017427.11	882.81760	421.64070	1.06600	10.16920	7.91110	K562	CCDC124
ACSM3	ENSG00000005187.7	9144.81160	6544.66550	0.48250	9.40170	7.22470	K562	CCDC124
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

125 RBPs can affect the gene expression of CCDC124 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CCDC124	ENSG00000007080.6	205.86350	1268.28790	-2.62310	75.57870	71.47550	K562	CCDC124
CCDC124	ENSG00000007080.6	946.51910	332.60440	1.50870	34.93360	32.68000	K562	PTBP1
CCDC124	ENSG00000007080.6	335.47610	105.58690	1.66770	22.71350	21.11160	HepG2	SAFB2
CCDC124	ENSG00000007080.6	833.09140	342.32140	1.28300	22.57510	19.98530	K562	MAGOH
CCDC124	ENSG00000007080.6	979.58180	1729.69980	-0.82030	19.76920	17.75150	K562	SF3A3
CCDC124	ENSG00000007080.6	12.80790	131.95790	-3.36500	19.65730	17.30860	K562	G3BP2
CCDC124	ENSG00000007080.6	816.66600	411.51640	0.98870	18.58830	17.24660	HepG2	UTP3
CCDC124	ENSG00000007080.6	717.59110	276.28110	1.37690	15.43570	14.28470	HepG2	AKAP1
CCDC124	ENSG00000007080.6	298.50190	118.56460	1.33200	14.67410	13.37090	HepG2	HNRNPU
CCDC124	ENSG00000007080.6	675.15020	326.08990	1.04980	14.48230	12.85920	K562	SRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 155 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CCDC124 is not available on ENCORE database.

1 RBPs can affect the splicing of CCDC124 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP	Bound by RBP
SE	CCDC124	ENSG00000007080.6	chr19	+	18053113	18053338			18047218	18047388	18053464	18053654	0.05600	0.00000	0.00028	included	HepG2	HNRNPK

Showing 1 to 1 of 1 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CCDC124

General Information

Functions

Localization(RBPImage: CCDC124)

Domains (AlphaFold: CCDC124)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CCDC124 is not avaliable on ENCORE database.

9 proteins are bound to CCDC124 RNA:

eCLIP assay for CCDC124 is not avaliable on ENCORE database.

Diffrential Expression

2,111 differentially expressed genes after Knockdown/Knockout CCDC124 protein :

125 RBPs can affect the gene expression of CCDC124 :

The Knockdown/knockout RNA-Seq assay for CCDC124 is not available on ENCORE database.

1 RBPs can affect the splicing of CCDC124 :

The Knockdown/knockout RNA-Seq assay for CCDC124 is not avaliable on ENCORE database.