HHLA3

General Information

Gene Name : HHLA3
Gene ID : ENSG00000197568.13
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HHLA3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HHLA3	ENSG00000197568.13	5.98	6.18	6.08	ENCSR000AEF
HepG2	HHLA3	ENSG00000197568.13	4.54	5.12	4.83	ENCSR985KAT
K562	HHLA3	ENSG00000197568.13	12.56	12.49	12.53	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HHLA3 is not avaliable on ENCORE database.

Proteins bound to RNA

HHLA3 RNA is bound by 2 proteins.

CanvasJS.com

eCLIP assay for HHLA3 is not avaliable on ENCORE database.

2 proteins are bound to HHLA3 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	70820598	70820643	+	5'-UTR,CDS	4.97663	5.39850	K562	DDX3X
chr1	70820731	70820777	+	CDS	4.39278	4.72754	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 2 of 2 entries

eCLIP assay for HHLA3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HHLA3 is not available on ENCORE database.
66 RBPs can affect the levels of HHLA3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HHLA3 is not available on ENCORE database.

66 RBPs can affect the gene expression of HHLA3 :

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Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HHLA3	ENSG00000197568.9	387.42110	125.56600	1.62540	18.59530	17.12490	K562	HNRNPC
HHLA3	ENSG00000197568.9	520.44530	215.24250	1.27370	17.16470	15.25990	K562	POLR2G
HHLA3	ENSG00000197568.9	626.44860	280.62050	1.15850	12.69740	10.92980	K562	PCBP3
HHLA3	ENSG00000197568.9	538.47770	252.91070	1.09020	11.65620	10.05420	K562	HSPD1
HHLA3	ENSG00000197568.9	222.07300	95.21830	1.22160	10.20280	9.31870	HepG2	ZNF622
HHLA3	ENSG00000197568.9	310.36480	122.81650	1.33740	9.10860	8.20570	HepG2	AKAP1
HHLA3	ENSG00000197568.9	178.08200	73.96580	1.26750	7.63300	6.87190	HepG2	RBM22
HHLA3	ENSG00000197568.9	172.89930	62.36550	1.47100	7.87990	6.75650	HepG2	HNRNPC
HHLA3	ENSG00000197568.9	310.34420	171.80570	0.85300	6.81360	5.59220	K562	MTPAP
HHLA3	ENSG00000197568.9	176.15500	83.54290	1.07620	6.04260	5.38130	HepG2	SRFBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 74 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HHLA3 is not available on ENCORE database.

4 RBPs can affect the splicing of HHLA3 :

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Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	HHLA3	ENSG00000197568.9	chr1	+	70832615	70832667	70832126	70832220	70833299	70833706	-0.19300	0.00005	0.00768	excluded	HepG2	DDX3X
SE	HHLA3	ENSG00000197568.9	chr1	+	70832615	70832667	70832126	70832220	70833299	70833706	0.29100	0.00041	0.01872	included	K562	HNRNPU
SE	HHLA3	ENSG00000197568.9	chr1	+	70832615	70832667	70832126	70832220	70833299	70833706	0.26600	0.00183	0.06253	included	K562	FXR1
SE	HHLA3	ENSG00000197568.9	chr1	+	70832615	70832667	70832126	70832220	70833299	70833706	-0.15800	0.00304	0.09555	excluded	HepG2	MATR3

Showing 1 to 4 of 4 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HHLA3

General Information

Functions

Localization

Domains (AlphaFold: HHLA3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HHLA3 is not avaliable on ENCORE database.

2 proteins are bound to HHLA3 RNA:

eCLIP assay for HHLA3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HHLA3 is not available on ENCORE database.

66 RBPs can affect the gene expression of HHLA3 :

The Knockdown/knockout RNA-Seq assay for HHLA3 is not available on ENCORE database.

4 RBPs can affect the splicing of HHLA3 :

The Knockdown/knockout RNA-Seq assay for HHLA3 is not avaliable on ENCORE database.