WDR77

General Information

Gene Name : WDR77
Gene ID : ENSG00000116455.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: WDR77)

Not Available

Antibody Validation

Cell Signaling Technology: 2018S

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	WDR77	ENSG00000116455.13	45.51	47.59	46.55	ENCSR000AEF
HepG2	WDR77	ENSG00000116455.13	76.15	50.88	63.52	ENCSR985KAT
K562	WDR77	ENSG00000116455.13	72.90	78.34	75.62	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
WDR77		2018S	1			Submitted, ENCORE2		BGKcLV42-105, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
WDR77	K562	CRISPR	WDR77-BGKcLV42-105,WDR77-BGKcLV42-106	NT-BGKcLV42-1,NT-BGKcLV42-2	49.8,59.1	Submitting	ENCORE2
WDR77	HepG2	CRISPR	BGHcLV45-79,BGHcLV45-80	BGHcLV45-1,BGHcLV45-2	discussion ,	NotSatisfied	ENCORE2
WDR77	HepG2	CRISPR	BGHcLV47-89,BGHcLV47-90	BGHcLV47-1,BGHcLV47-2	62.4,65.6	LibPreping	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
WDR77	Product_ID: 2018S Lot_ID: 1 Source: Cell Signaling Technology Target Name: WDR77-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for WDR77 is not avaliable on ENCORE database.

Proteins bound to RNA

WDR77 RNA is bound by 21 proteins.

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eCLIP assay for WDR77 is not avaliable on ENCORE database.

21 proteins are bound to WDR77 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	111991717	111991818	-	5'-UTR,CDS,intron-Distal	4.26723	40.97135	K562	DDX3X
chr1	111991479	111991614	-	intron-Distal,intron-Proximal	5.15729	33.44141	HepG2	RBFOX2
chr1	111991818	111991867	-	5'-UTR,intron-Distal	4.50499	27.54804	K562	DDX3X
chr1	111991159	111991228	-	intron-Distal,intron-Proximal	5.79490	21.49406	HepG2	PRPF8
chr1	111983909	111984069	-	CDS,intron-Distal,intron-Proximal	3.58094	19.48261	HepG2	U2AF2
chr1	111991228	111991286	-	CDS,intron-Distal,intron-Proximal	7.23767	16.64887	HepG2	PRPF8
chr1	111983419	111983513	-	3'-UTR,intron-Distal	4.35831	16.54613	K562	UPF1
chr1	111991112	111991239	-	intron-Distal,intron-Proximal	5.74665	15.05491	HepG2	EFTUD2
chr1	111991466	111991586	-	intron-Distal,intron-Proximal	5.72577	14.01891	K562	RBFOX2
chr1	111983606	111983651	-	3'-UTR,intron-Distal	4.37527	13.81585	K562	TARDBP
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 47 entries

eCLIP assay for WDR77 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for WDR77 is not available on ENCORE database.
122 RBPs can affect the levels of WDR77.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for WDR77 is not available on ENCORE database.

122 RBPs can affect the gene expression of WDR77 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
WDR77	ENSG00000116455.9	1732.91080	850.14690	1.02730	26.71190	24.21270	K562	EIF3G
WDR77	ENSG00000116455.9	1660.76140	829.64330	1.00120	24.75140	23.42520	HepG2	PTBP1
WDR77	ENSG00000116455.9	1326.19340	696.22960	0.92960	22.91580	21.43940	HepG2	UTP3
WDR77	ENSG00000116455.9	470.13630	930.87230	-0.98550	20.74480	18.97290	HepG2	PRPF4
WDR77	ENSG00000116455.9	974.25170	1629.32760	-0.74190	18.79460	17.71270	HepG2	SSB
WDR77	ENSG00000116455.9	1601.18490	898.62390	0.83330	15.26510	13.96650	HepG2	QKI
WDR77	ENSG00000116455.9	1456.38210	901.63780	0.69170	14.25100	13.35690	HepG2	SRSF1
WDR77	ENSG00000116455.9	362.14690	788.40390	-1.12240	14.58360	13.01090	HepG2	NSUN2
WDR77	ENSG00000116455.9	2117.74510	899.81000	1.23470	13.81840	12.57100	K562	FXR1
WDR77	ENSG00000116455.9	772.24820	1220.92020	-0.66080	13.36330	12.01840	HepG2	SLBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 149 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for WDR77 is not available on ENCORE database.

9 RBPs can affect the splicing of WDR77 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	WDR77	ENSG00000116455.9	chr1	-	111984120	111984226	111983919	111984011	111984646	111984715	-0.07400	0.00000	0.00119	excluded	K562	GPKOW
SE	WDR77	ENSG00000116455.9	chr1	-	111984120	111984226	111983919	111984011	111984646	111984715	0.16400	0.00000	0.00000	included	K562	HNRNPU
A3SS	WDR77	ENSG00000116455.9	chr1	-	111984646	111984863	111984646	111984715	111985274	111985383	0.06200	0.00000	0.00000	longer	K562	AQR
A3SS	WDR77	ENSG00000116455.9	chr1	-	111991264	111991442	111991264	111991426	111991676	111991998	0.11200	0.00000	0.00000	longer	K562	AQR
RI	WDR77	ENSG00000116455.9	chr1	-	111986488	111986732	111986488	111986543	111986675	111986732	0.05500	0.00000	0.00000	included	K562	AQR
A3SS	WDR77	ENSG00000116455.9	chr1	-	111984646	111984751	111984646	111984715	111985274	111985383	0.08600	0.00003	0.00191	longer	K562	U2AF2
SE	WDR77	ENSG00000116455.9	chr1	-	111984120	111984226	111983919	111984011	111984646	111984715	0.05300	0.00014	0.09643	included	K562	TROVE2
SE	WDR77	ENSG00000116455.9	chr1	-	111984120	111984226	111983919	111984011	111984646	111984715	0.08700	0.00014	0.07569	included	HepG2	LIN28B
SE	WDR77	ENSG00000116455.9	chr1	-	111986288	111986347	111985970	111986016	111986488	111986543	0.07700	0.00023	0.00790	included	HepG2	HNRNPK
SE	WDR77	ENSG00000116455.9	chr1	-	111984120	111984226	111983919	111984011	111984646	111984715	0.05700	0.00190	0.06504	included	K562	PTBP1

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

WDR77

General Information

Functions

Localization

Domains (AlphaFold: WDR77)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for WDR77 is not avaliable on ENCORE database.

21 proteins are bound to WDR77 RNA:

eCLIP assay for WDR77 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for WDR77 is not available on ENCORE database.

122 RBPs can affect the gene expression of WDR77 :

The Knockdown/knockout RNA-Seq assay for WDR77 is not available on ENCORE database.

9 RBPs can affect the splicing of WDR77 :

The Knockdown/knockout RNA-Seq assay for WDR77 is not avaliable on ENCORE database.