RBM4

General Information

Gene Name : RBM4
Gene ID : ENSG00000173933.20
Essential Gene : No

Functions

Splicing regulation
microRNA processing
Translation regulation

Localization(RBPImage: RBM4)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Speckles
Cytoplasm
Compartment/Organelle
P bodies
Unknown Cyto Foci
Cytosolic
Nuclear release mitosis

Domains (AlphaFold: RBM4)

RRM
ZNF

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RBM4	ENSG00000173933.20	72.40	82.40	77.40	ENCSR000AEF
HepG2	RBM4	ENSG00000173933.20	155.56	107.90	131.73	ENCSR985KAT
K562	RBM4	ENSG00000173933.20	83.10	82.16	82.63	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	RBM4-BG293LV04-WT293		RBM4	293T	Released		shRNA	KD% = ,
knockdown followed by RNA-seq	RBM4-BG293LV06-WT293		RBM4	293T	Released		shRNA	KD% = ,
RNA Bind-n-Seq	RBNS: RBM4	ENCSR331BKR	RBM4	cell-free sample	Released	ENCSR990LWK

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
RBM4	K562	shRNA	BGKLV13-29,BGKLV13-30	BGKLV13-1,BGKLV13-2		NotSatisfied	ENCODE3
RBM4	K562	shRNA	BGKLV34-29,BGKLV34-30	BGKLV34-1,BGKLV34-2		NotSatisfied	ENCODE3
RBM4	HepG2	shRNA	BGHLV26-41,BGHLV26-42	BGHLV26-1,BGHLV26-2	redo transfection,redo transfection	NotSatisfied	ENCODE3
RBM4	HepG2	shRNA	BGHLV33-25,BGHLV33-26	BGHLV33-1,BGHLV33-2		NotSatisfied	ENCODE3
RBM4	Ribo-STAMP-293T	shRNA	BGRSLV01-13,BGRSLV01-14	BGRSLV01-1,BGRSLV01-2		NotSatisfied	ENCORE2
RBM4	Ribo-STAMP-293T	shRNA	BGRSLV02-15,BGRSLV02-16	BGRSLV02-1,BGRSLV02-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	BG293LV01-53,BG293LV01-54	BG293LV01-1,BG293LV01-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	BG293LV01-55,BG293LV01-56	BG293LV01-1,BG293LV01-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	BG293LV01-57,BG293LV01-58	BG293LV01-1,BG293LV01-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	RBM4-BG293LV04-55,RBM4-BG293LV04-56	NT-BG293LV04-1,NT-BG293LV04-2	,	Released	ENCORE2
RBM4	293T	shRNA	BG293LV04-57,BG293LV04-58	BG293LV04-1,BG293LV04-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	BG293LV04-59,BG293LV04-60	BG293LV04-1,BG293LV04-2		NotSatisfied	ENCORE2
RBM4	293T	shRNA	RBM4-BG293LV06-47,RBM4-BG293LV06-48	NT-BG293LV06-1,NT-BG293LV06-2	,	Released	ENCORE2

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
RBM4	RBM4		Released	ENCODE3

Localization Image in HepG2

RBM4: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Speckles

Cytoplasm

Compartment/Organelle

P bodies

Unknown Cyto Foci

Cytosolic

Nuclear release mitosis

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RBM4 is not avaliable on ENCORE database.

The binding motifs of RBM4

Proteins bound to RNA

RBM4 RNA is bound by 74 proteins.

CanvasJS.com

eCLIP assay for RBM4 is not avaliable on ENCORE database.

74 proteins are bound to RBM4 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	66413644	66413756	+	3'-UTR,intron-Distal	4.79014	400.00000	K562	PTBP1
chr11	66413635	66413755	+	3'-UTR,intron-Distal	4.22601	61.29734	HepG2	PTBP1
chr11	66384259	66384283	+	5'-UTR,CDS	6.41326	58.56692	K562	RBM15
chr11	66384255	66384259	+	5'-UTR,CDS	6.24274	50.00583	K562	RBM15
chr11	66384283	66384292	+	5'-UTR,CDS	6.16870	49.29371	K562	RBM15
chr11	66394560	66394609	+	3'-UTR,intron-Distal	4.16858	41.25830	K562	PABPC4
chr11	66384146	66384186	+	5'-UTR	5.50832	38.09908	K562	RBM15
chr11	66384429	66384520	+	5'-UTR,CDS	5.46402	36.41653	K562	RBM15
chr11	66384600	66384700	+	intron-Distal,intron-Proximal	5.31699	35.29801	K562	RBM15
chr11	66384576	66384713	+	intron-Distal,intron-Proximal	3.85094	32.89606	HepG2	EFTUD2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 351 entries

eCLIP assay for RBM4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for RBM4 is not available on ENCORE database.
65 RBPs can affect the levels of RBM4.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RBM4 is not available on ENCORE database.

65 RBPs can affect the gene expression of RBM4 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RBM4	ENSG00000173933.15	3531.20990	1577.77730	1.16220	31.80260	30.11740	HepG2	UTP3
RBM4	ENSG00000173933.15	3363.96240	1957.49760	0.78110	27.58720	25.90360	K562	AGGF1
RBM4	ENSG00000173933.15	4954.22640	2020.05160	1.29420	24.08070	22.48950	K562	PUS1
RBM4	ENSG00000173933.15	4694.92000	2473.20070	0.92460	19.93460	18.53010	K562	AQR
RBM4	ENSG00000173933.15	1994.22330	1295.52630	0.62220	13.20080	11.97910	K562	FXR1
RBM4	ENSG00000173933.15	2838.87140	1941.92740	0.54770	11.74750	10.83380	HepG2	RBM22
RBM4	ENSG00000173933.15	2896.22640	1758.83140	0.71950	11.91020	10.78460	HepG2	BOP1
RBM4	ENSG00000173933.15	3543.02320	1968.19710	0.84800	11.76470	10.55150	K562	RBM15
RBM4	ENSG00000173933.15	1339.94650	2006.49080	-0.58250	11.80200	10.31060	HepG2	EIF4G1
RBM4	ENSG00000173933.15	1045.63510	1482.64670	-0.50380	8.76670	7.73310	HepG2	HNRNPU
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 72 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RBM4 is not available on ENCORE database.

22 RBPs can affect the splicing of RBM4 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66407170	66407594	66413497	66413938	-0.18600	0.00000	0.00043	excluded	HepG2	DKC1
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66407170	66407594	66413497	66413938	-0.20000	0.00000	0.00000	excluded	HepG2	AKAP1
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413938	0.10300	0.00000	0.00000	included	K562	PUS1
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413938	-0.16500	0.00000	0.00000	excluded	HepG2	SF3A3
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413938	-0.24100	0.00000	0.00000	excluded	K562	PTBP1
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413940	0.11500	0.00001	0.00024	included	K562	AQR
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413938	-0.14500	0.00001	0.00102	excluded	HepG2	HNRNPC
SE	RBM4	ENSG00000173933.15	chr11	+	66406029	66406223	66384096	66384528	66407170	66408663	0.23500	0.00003	0.00935	included	K562	HNRNPM
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413940	0.08800	0.00004	0.00249	included	K562	AKAP8L
SE	RBM4	ENSG00000173933.15	chr11	+	66410920	66411611	66406405	66407594	66413497	66413940	0.09300	0.00004	0.00189	included	K562	AGGF1

Showing 1 to 10 of 28 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RBM4

General Information

Functions

Localization(RBPImage: RBM4)

Domains (AlphaFold: RBM4)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RBM4 is not avaliable on ENCORE database.

74 proteins are bound to RBM4 RNA:

eCLIP assay for RBM4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RBM4 is not available on ENCORE database.

65 RBPs can affect the gene expression of RBM4 :

The Knockdown/knockout RNA-Seq assay for RBM4 is not available on ENCORE database.

22 RBPs can affect the splicing of RBM4 :

The Knockdown/knockout RNA-Seq assay for RBM4 is not avaliable on ENCORE database.