PNPLA3

General Information

Gene Name : PNPLA3
Gene ID : ENSG00000100344.10
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PNPLA3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PNPLA3	ENSG00000100344.10	0.00	0.00	0.00	ENCSR000AEF
HepG2	PNPLA3	ENSG00000100344.10	18.62	9.85	14.23	ENCSR985KAT
K562	PNPLA3	ENSG00000100344.10	0.04	0.32	0.18	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PNPLA3 is not avaliable on ENCORE database.

Proteins bound to RNA

PNPLA3 RNA is bound by 29 proteins.

CanvasJS.com

eCLIP assay for PNPLA3 is not avaliable on ENCORE database.

29 proteins are bound to PNPLA3 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr22	44342593	44342738	+	3'-UTR,intron-Distal	4.20725	20.56330	HepG2	AKAP1
chr22	44330450	44330515	+	5'-UTR,CDS,intron-Proximal	4.71030	20.23438	HepG2	U2AF2
chr22	44340677	44340723	+	intron-Proximal	3.59808	17.85496	HepG2	PRPF8
chr22	44342927	44343017	+	3'-UTR,intron-Distal	4.01167	16.90696	HepG2	UPF1
chr22	44339168	44339223	+	intron-Distal	4.26321	16.69254	HepG2	MATR3
chr22	44342571	44342640	+	3'-UTR,intron-Distal	4.26790	15.91272	HepG2	UPF1
chr22	44333079	44333152	+	5'-UTR,CDS	3.31801	15.58494	HepG2	PPIG
chr22	44333013	44333092	+	5'-UTR,CDS	4.43317	14.87701	HepG2	GRWD1
chr22	44339091	44339168	+	intron-Distal	4.10754	14.64902	HepG2	MATR3
chr22	44346018	44346138	+	intron-Distal	3.90043	14.63268	HepG2	UPF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 71 entries

eCLIP assay for PNPLA3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PNPLA3 is not available on ENCORE database.
112 RBPs can affect the levels of PNPLA3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PNPLA3 is not available on ENCORE database.

112 RBPs can affect the gene expression of PNPLA3 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PNPLA3	ENSG00000100344.6	128.97600	1205.16180	-3.22410	79.69040	77.48880	HepG2	AKAP1
PNPLA3	ENSG00000100344.6	215.49580	801.76560	-1.89550	54.18010	52.69840	HepG2	SRFBP1
PNPLA3	ENSG00000100344.6	168.62060	619.85040	-1.87810	47.82920	45.98240	HepG2	PUM1
PNPLA3	ENSG00000100344.6	1601.59730	696.12550	1.20200	43.53320	42.08620	HepG2	SSB
PNPLA3	ENSG00000100344.6	1021.60890	256.63010	1.99300	42.35370	40.35230	HepG2	HNRNPLL
PNPLA3	ENSG00000100344.6	1385.59300	695.37010	0.99460	29.68700	28.06020	HepG2	PUS1
PNPLA3	ENSG00000100344.6	258.90940	731.74250	-1.49890	29.42290	27.15280	HepG2	RBM15
PNPLA3	ENSG00000100344.6	381.58300	868.22400	-1.18610	28.53200	27.11940	HepG2	SRSF9
PNPLA3	ENSG00000100344.6	279.94430	682.70940	-1.28610	28.10660	26.64310	HepG2	ACO1
PNPLA3	ENSG00000100344.6	911.09980	324.31060	1.49010	27.93410	26.28180	HepG2	HNRNPA1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 113 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PNPLA3 is not available on ENCORE database.

11 RBPs can affect the splicing of PNPLA3 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A5SS	PNPLA3	ENSG00000100344.6	chr22	+	44328886	44329123	44328886	44328967	44330485	44330546	0.41700	0.00000	0.00000	longer	HepG2	HNRNPK
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.16900	0.00001	0.01397	included	HepG2	LIN28B
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.11900	0.00001	0.01235	included	HepG2	UPF1
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.12300	0.00002	0.00363	included	HepG2	G3BP1
A5SS	PNPLA3	ENSG00000100344.6	chr22	+	44328886	44329123	44328886	44328967	44330485	44330546	0.19700	0.00005	0.01101	longer	HepG2	MATR3
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.15700	0.00014	0.01522	included	HepG2	TIAL1
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.19300	0.00020	0.03938	included	HepG2	RBM15
A5SS	PNPLA3	ENSG00000100344.6	chr22	+	44328886	44329123	44328886	44328967	44330485	44330546	0.22100	0.00029	0.03776	longer	HepG2	TAF15
SE	PNPLA3	ENSG00000100344.6	chr22	+	44337353	44337481	44335872	44336005	44340570	44340675	0.09000	0.00048	0.03451	included	HepG2	AKAP1
SE	PNPLA3	ENSG00000100344.6	chr22	+	44335215	44335333	44332930	44333152	44335872	44336005	0.13900	0.00066	0.02799	included	HepG2	HNRNPC

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PNPLA3

General Information

Functions

Localization

Domains (AlphaFold: PNPLA3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PNPLA3 is not avaliable on ENCORE database.

29 proteins are bound to PNPLA3 RNA:

eCLIP assay for PNPLA3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PNPLA3 is not available on ENCORE database.

112 RBPs can affect the gene expression of PNPLA3 :

The Knockdown/knockout RNA-Seq assay for PNPLA3 is not available on ENCORE database.

11 RBPs can affect the splicing of PNPLA3 :

The Knockdown/knockout RNA-Seq assay for PNPLA3 is not avaliable on ENCORE database.