EIF3B

General Information

Gene Name : EIF3B
Gene ID : ENSG00000106263.17
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EIF3B)

Not Available

Antibody Validation

Bethyl Labs: A301-761A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EIF3B	ENSG00000106263.17	182.48	187.05	184.76	ENCSR000AEF
HepG2	EIF3B	ENSG00000106263.17	170.48	183.72	177.10	ENCSR985KAT
K562	EIF3B	ENSG00000106263.17	358.01	332.29	345.15	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
EIF3B		A301-761A	2					BGKcLV38-47, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
EIF3B	K562	CRISPR			EIF3B-BGKcLV38-47,EIF3B-BGKcLV38-48	NT-BGKcLV38-1,NT-BGKcLV38-2	71.5,75.2	Submitting	ENCORE2
EIF3B	HepG2	CRISPR			BGHcLV39-55,BGHcLV39-56	BGHcLV39-1,BGHcLV39-2	0.0,0.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
EIF3B	Product_ID: A301-761A Lot_ID: 2 Source: Bethyl Labs Target Name: EIF3B-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EIF3B is not avaliable on ENCORE database.

Proteins bound to RNA

EIF3B RNA is bound by 56 proteins.

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eCLIP assay for EIF3B is not avaliable on ENCORE database.

56 proteins are bound to EIF3B RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr7	2406077	2406126	+	CDS,intron-Proximal	5.51892	52.69639	HepG2	PRPF8
chr7	2415176	2415199	+	intron-Proximal	5.93037	49.60417	K562	AQR
chr7	2403954	2404046	+	CDS,intron-Proximal	5.00430	47.70358	K562	SF3B4
chr7	2415199	2415204	+	intron-Proximal	6.62253	41.38589	K562	AQR
chr7	2394487	2394639	+	5'-UTR,CDS,intron-Distal	5.46569	40.44160	K562	FMR1
chr7	2415161	2415176	+	CDS,intron-Proximal	4.57051	38.49165	K562	AQR
chr7	2406633	2406726	+	CDS,intron-Proximal	4.00532	33.61313	K562	EFTUD2
chr7	2406051	2406077	+	CDS	5.19944	31.62523	HepG2	PRPF8
chr7	2418407	2418468	+	intron-Proximal	5.47496	31.52931	K562	AQR
chr7	2406079	2406127	+	CDS,intron-Proximal	4.88630	30.53269	K562	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 363 entries

eCLIP assay for EIF3B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EIF3B is not available on ENCORE database.
113 RBPs can affect the levels of EIF3B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EIF3B is not available on ENCORE database.

113 RBPs can affect the gene expression of EIF3B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EIF3B	ENSG00000106263.13	1648.09900	3864.77690	-1.22960	39.03160	36.60420	HepG2	MSI2
EIF3B	ENSG00000106263.13	4253.32700	6490.72440	-0.60980	23.10000	21.93630	HepG2	SSB
EIF3B	ENSG00000106263.13	2515.41900	5422.18430	-1.10810	22.24250	20.64890	HepG2	DDX3X
EIF3B	ENSG00000106263.13	11786.15120	8010.34740	0.55710	21.50260	20.03170	K562	AGGF1
EIF3B	ENSG00000106263.13	8359.14910	12328.23000	-0.56050	16.59220	15.05030	K562	EIF2S2
EIF3B	ENSG00000106263.13	4798.98610	7838.16330	-0.70780	16.12000	14.75760	K562	HNRNPC
EIF3B	ENSG00000106263.13	1858.61300	3649.15090	-0.97330	15.98110	14.59050	HepG2	SUPV3L1
EIF3B	ENSG00000106263.13	2077.42990	3605.27220	-0.79530	15.47010	14.01880	HepG2	DDX21
EIF3B	ENSG00000106263.13	3291.34800	5276.63760	-0.68090	15.78600	13.83700	K562	U2AF2
EIF3B	ENSG00000106263.13	3433.74140	4863.15840	-0.50210	14.16990	13.17250	HepG2	ZNF622
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 134 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EIF3B is not available on ENCORE database.

36 RBPs can affect the splicing of EIF3B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	EIF3B	ENSG00000106263.13	chr7	+	2411379	2411484	2409106	2409317	2412307	2412430	-0.07100	0.00000	excluded	K562	AQR
SE	EIF3B	ENSG00000106263.13	chr7	+	2406189	2406226	2405892	2406083	2406633	2406680	-0.09900	0.00000	excluded	K562	AQR
A3SS	EIF3B	ENSG00000106263.13	chr7	+	2419838	2420375	2419913	2420375	2419028	2419146	-0.19400	0.00104	shorter	K562	EFTUD2
A3SS	EIF3B	ENSG00000106263.13	chr7	+	2406568	2406754	2406633	2406754	2406189	2406226	0.09000	0.00000	longer	K562	U2AF2
A3SS	EIF3B	ENSG00000106263.13	chr7	+	2412281	2412430	2412307	2412430	2411379	2411484	0.12100	0.00000	longer	K562	AQR
A3SS	EIF3B	ENSG00000106263.13	chr7	+	2406568	2406680	2406633	2406680	2406189	2406226	0.05100	0.00000	longer	K562	U2AF1
A5SS	EIF3B	ENSG00000106263.13	chr7	+	2416584	2416769	2416584	2416710	2418323	2418401	0.05100	0.00000	longer	K562	PUS1
A5SS	EIF3B	ENSG00000106263.13	chr7	+	2418321	2418517	2418321	2418401	2418768	2418877	0.05800	0.00000	longer	K562	PUS1
RI	EIF3B	ENSG00000106263.13	chr7	+	2418323	2418877	2418323	2418401	2418768	2418877	0.11200	0.00000	included	K562	PUS1
RI	EIF3B	ENSG00000106263.13	chr7	+	2405951	2406226	2405951	2406083	2406159	2406226	0.08000	0.00001	included	K562	PUS1

Showing 1 to 10 of 62 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EIF3B

General Information

Functions

Localization

Domains (AlphaFold: EIF3B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EIF3B is not avaliable on ENCORE database.

56 proteins are bound to EIF3B RNA:

eCLIP assay for EIF3B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EIF3B is not available on ENCORE database.

113 RBPs can affect the gene expression of EIF3B :

The Knockdown/knockout RNA-Seq assay for EIF3B is not available on ENCORE database.

36 RBPs can affect the splicing of EIF3B :

The Knockdown/knockout RNA-Seq assay for EIF3B is not avaliable on ENCORE database.