DDX17

General Information

Gene Name : DDX17
Gene ID : ENSG00000100201.20
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: DDX17)

Not Available

Antibody Validation

Bethyl Labs: A300-509A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DDX17	ENSG00000100201.20	249.23	210.74	229.99	ENCSR000AEF
HepG2	DDX17	ENSG00000100201.20	130.47	141.00	135.74	ENCSR985KAT
K562	DDX17	ENSG00000100201.20	115.34	124.30	119.82	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Controls	Method	Note
knockdown followed by RNA-seq	DDX17-BGKcLV28-K562	ENCSR613ZVB	DDX17	K562	Released	ENCSR220DTX	CRISPR	KD% = 61.8,52.7
knockdown followed by RNA-seq	DDX17-BG293LV03-WT293		DDX17	293T	Released		shRNA	KD% = ,
knockdown followed by RNA-seq	DDX17-BG293LV06-WT293		DDX17	293T	Released		shRNA	KD% = ,

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
DDX17	ENCAB300RAY	A300-509A	2			Released, ENCODE4		BGKcLV28-69, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
DDX17	K562	CRISPR	ENCSR613ZVB	ENCSR220DTX	DDX17-BGKcLV28-69,DDX17-BGKcLV28-70	NT-BGKcLV28-1,NT-BGKcLV28-2	61.8,52.7	Released	ENCODE4
DDX17	HepG2	CRISPR			BGHcLV29-69,BGHcLV29-70	BGHcLV29-1,BGHcLV29-2	no clear band,	NotSatisfied	ENCODE4
DDX17	HepG2	CRISPR			BGHcLV49-29,BGHcLV49-30	BGHcLV49-1,BGHcLV49-2		NotSatisfied	ENCORE2
DDX17	HepG2	CRISPR			BGHcLV49-31,BGHcLV49-32	BGHcLV49-1,BGHcLV49-2		NotSatisfied	ENCORE2
DDX17	293T	shRNA			DDX17-BG293LV03-9,DDX17-BG293LV03-10	NT-BG293LV03-1,NT-BG293LV03-2	,	Released	ENCORE2
DDX17	293T	shRNA			DDX17-BG293LV06-115B,DDX17-BG293LV06-116B	NT-BG293LV06-1B,NT-BG293LV06-2B	,	Released	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
DDX17	Product_ID: A300-509A Lot_ID: 2 Source: Bethyl Labs Target Name: DDX17-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DDX17 is not avaliable on ENCORE database.

Proteins bound to RNA

DDX17 RNA is bound by 67 proteins.

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eCLIP assay for DDX17 is not avaliable on ENCORE database.

67 proteins are bound to DDX17 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr22	38879518	38879615	-	3'-UTR,intron-Distal	5.08378	400.00000	K562	PUM2
chr22	38884231	38884267	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.97042	400.00000	K562	SF3B4
chr22	38884222	38884231	-	5'-UTR,intron-Distal,intron-Proximal	3.61638	87.29513	K562	SF3B4
chr22	38884191	38884266	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.54976	64.76424	HepG2	SF3A3
chr22	38884169	38884222	-	5'-UTR,intron-Distal,intron-Proximal	3.29570	63.10875	K562	SF3B4
chr22	38879463	38879516	-	3'-UTR,intron-Distal,intron-Proximal	4.97711	60.04644	K562	PUM2
chr22	38881505	38881536	-	3'-UTR,intron-Distal	3.49897	59.25196	K562	FAM120A
chr22	38895408	38895464	-	CDS,intron-Distal	4.06977	58.82939	HepG2	BCLAF1
chr22	38894442	38894521	-	CDS,intron-Distal,intron-Proximal	4.97088	56.59534	K562	DDX24
chr22	38884008	38884114	-	5'-UTR,CDS,intron-Distal	3.57652	55.97922	HepG2	GRWD1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 283 entries

eCLIP assay for DDX17 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for DDX17 is not available on ENCORE database.
95 RBPs can affect the levels of DDX17.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for DDX17 is not available on ENCORE database.

95 RBPs can affect the gene expression of DDX17 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DDX17	ENSG00000100201.14	5617.78600	10242.28920	-0.86650	61.32490	59.06350	HepG2	ZC3H8
DDX17	ENSG00000100201.14	7177.82800	12529.72020	-0.80370	33.63270	31.65480	K562	FXR1
DDX17	ENSG00000100201.14	7833.06980	11314.26070	-0.53050	29.20520	27.48070	HepG2	SMN1
DDX17	ENSG00000100201.14	7073.59680	10680.51330	-0.59450	22.83690	21.41710	HepG2	TRIM56
DDX17	ENSG00000100201.14	8198.16760	14441.68720	-0.81690	22.28940	20.47630	K562	PTBP1
DDX17	ENSG00000100201.14	13794.66110	20154.15930	-0.54700	19.66350	18.07580	K562	DDX47
DDX17	ENSG00000100201.14	17218.61450	11247.59080	0.61430	18.93140	17.65340	HepG2	TAF15
DDX17	ENSG00000100201.14	9416.92010	13086.12290	-0.47470	17.08060	15.78100	HepG2	UTP3
DDX17	ENSG00000100201.14	8949.38450	14864.54790	-0.73200	16.53060	14.34010	K562	MAGOH
DDX17	ENSG00000100201.14	5700.27600	10037.56810	-0.81630	16.06200	14.23320	K562	PRPF8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 107 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for DDX17 is not available on ENCORE database.

53 RBPs can affect the splicing of DDX17 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	DDX17	ENSG00000100201.14	chr22	-	38885232	38885463	38884021	38884120	38888060	38888120	-0.09300	0.00001	excluded	K562	FXR1
SE	DDX17	ENSG00000100201.14	chr22	-	38885227	38885463	38883883	38884120	38888060	38888120	0.15300	0.00002	included	K562	U2AF1
SE	DDX17	ENSG00000100201.14	chr22	-	38885227	38885463	38883883	38884120	38888060	38888120	0.07400	0.00165	included	HepG2	FUS
SE	DDX17	ENSG00000100201.14	chr22	-	38895674	38895718	38895404	38895504	38897134	38897285	0.24200	0.00000	included	K562	HNRNPC
A3SS	DDX17	ENSG00000100201.14	chr22	-	38889714	38889917	38889714	38889776	38890025	38890136	0.05700	0.00000	longer	K562	AQR
RI	DDX17	ENSG00000100201.14	chr22	-	38883883	38888120	38883883	38884120	38888060	38888120	-0.33400	0.00000	excluded	K562	SRSF1
RI	DDX17	ENSG00000100201.14	chr22	-	38883883	38888120	38883883	38884120	38888060	38888120	0.18100	0.00014	included	HepG2	SUPV3L1
RI	DDX17	ENSG00000100201.14	chr22	-	38883883	38888120	38883883	38884120	38888060	38888120	-0.30700	0.00000	excluded	K562	PRPF8
RI	DDX17	ENSG00000100201.14	chr22	-	38883883	38888120	38883883	38884120	38888060	38888120	0.25200	0.00000	included	HepG2	IGF2BP3
RI	DDX17	ENSG00000100201.14	chr22	-	38883883	38888120	38883883	38884120	38888060	38888120	0.30900	0.00000	included	HepG2	FTO

Showing 1 to 10 of 70 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DDX17

General Information

Functions

Localization

Domains (AlphaFold: DDX17)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DDX17 is not avaliable on ENCORE database.

67 proteins are bound to DDX17 RNA:

eCLIP assay for DDX17 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for DDX17 is not available on ENCORE database.

95 RBPs can affect the gene expression of DDX17 :

The Knockdown/knockout RNA-Seq assay for DDX17 is not available on ENCORE database.

53 RBPs can affect the splicing of DDX17 :

The Knockdown/knockout RNA-Seq assay for DDX17 is not avaliable on ENCORE database.