TUT1

General Information

Gene Name       : TUT1
Gene ID             : ENSG00000149016.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TUT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TUT1ENSG00000149016.156.019.507.75ENCSR000AEF
HepG2TUT1ENSG00000149016.158.745.737.24ENCSR985KAT
K562TUT1ENSG00000149016.1519.3215.3417.33ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq TUT1-BGRSLV06-RS293TUT1Ribo-STAMP-293TReleased   shRNAKD% = ,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
TUT1Ribo-STAMP-293TshRNATUT1-BGRSLV06-47,TUT1-BGRSLV06-48NT-BGRSLV06-1,NT-BGRSLV06-2,ReleasedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TUT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TUT1 RNA is bound by 7 proteins.  







eCLIP assay for TUT1 is not avaliable on ENCORE database.





7 proteins are bound to TUT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116234254162342624-3'-UTR,CDS,intron-Distal3.740343.62357HepG2U2AF2
chr116234889162348973-3'-UTR,CDS,intron-Distal,intron-Proximal4.670716.76118K562LIN28B
chr116235887462358981-5'-UTR,CDS,intron-Distal5.557366.69401K562DDX3X
chr116234465362344706-CDS,intron-Distal,intron-Proximal3.919603.86355HepG2PPIG
chr116234300562343119-CDS,intron-Distal3.858015.68843K562DDX6
chr116234475162344812-CDS,intron-Distal,intron-Proximal3.815726.26407K562SF3B4
chr116234412462344218-CDS,intron-Distal,intron-Proximal3.529165.30777HepG2PPIG
chr116234508962345154-intron-Distal4.154866.11515K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TUT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TUT1 is not available on ENCORE database.

  • 67 RBPs can affect the levels of TUT1.  








The Knockdown/knockout RNA-Seq assay for TUT1 is not available on ENCORE database.





67 RBPs can affect the gene expression of TUT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TUT1ENSG00000149016.11632.84040454.007200.479005.011804.24040HepG2ACO1
TUT1ENSG00000149016.11572.18980456.129200.327002.371601.65570HepG2AKAP8L
TUT1ENSG00000149016.11302.66270177.036600.773603.435202.77620HepG2BOP1
TUT1ENSG00000149016.11703.33420453.895200.631808.946007.88010HepG2CKAP4
TUT1ENSG00000149016.11234.21830162.519500.527102.052101.44980HepG2CPSF6
TUT1ENSG00000149016.11493.67810404.202600.288401.994701.43200HepG2CELF1
TUT1ENSG00000149016.11523.91870434.501200.269902.096201.43820HepG2DAZAP1
TUT1ENSG00000149016.11563.90490434.358400.376502.762502.08570HepG2DKC1
TUT1ENSG00000149016.11394.41950259.263400.605204.804503.90070HepG2DNAJC21
TUT1ENSG00000149016.11344.67750257.021300.423302.895702.23080HepG2DNAJC2
TUT1ENSG00000149016.11793.11630614.456000.368101.917201.38090HepG2EIF4A3
TUT1ENSG00000149016.11550.98660410.708500.423802.201401.46940HepG2EIF4G2
TUT1ENSG00000149016.11374.19970162.818301.200403.583802.42220HepG2FTO
TUT1ENSG00000149016.11309.52200184.201800.748703.709802.97780HepG2GPKOW
TUT1ENSG00000149016.11388.67120291.161600.416602.013101.41130HepG2HNRNPC
TUT1ENSG00000149016.11451.62000304.467000.568704.775803.86590HepG2HNRNPF
TUT1ENSG00000149016.11679.17140395.762200.7790012.2782010.95460HepG2HNRNPL
TUT1ENSG00000149016.11358.94510175.789601.029806.856005.91590HepG2HNRNPLL
TUT1ENSG00000149016.11452.11550289.235500.644306.303305.41870HepG2HNRNPU
TUT1ENSG00000149016.11397.25420299.811000.405902.176901.53030HepG2IGF2BP1
TUT1ENSG00000149016.11435.58330295.441800.560005.075104.10760HepG2ILF2
TUT1ENSG00000149016.11236.35530338.13840-0.516702.891802.06680HepG2MSI2
TUT1ENSG00000149016.11594.66860430.856700.464804.280703.33240HepG2NOL12
TUT1ENSG00000149016.11272.51410155.890500.805704.264503.34110HepG2NSUN2
TUT1ENSG00000149016.11454.04960304.048300.578402.865501.80650HepG2PCBP2
TUT1ENSG00000149016.11521.54370411.322500.342402.173201.63600HepG2PUF60
TUT1ENSG00000149016.11664.53500462.433800.523005.970505.12760HepG2PUS1
TUT1ENSG00000149016.11169.92520293.33850-0.787703.163402.41320HepG2RAVER1
TUT1ENSG00000149016.11612.04270441.690400.470503.539002.58020HepG2RBM15
TUT1ENSG00000149016.11392.47590632.58300-0.688706.588605.58760HepG2RBM25
TUT1ENSG00000149016.11412.95830257.567700.680906.551005.62250HepG2SAFB2
TUT1ENSG00000149016.11312.19240173.981500.843405.346604.38860HepG2SF3B1
TUT1ENSG00000149016.11565.10320394.471400.518505.059604.15620HepG2SLBP
TUT1ENSG00000149016.11366.83570193.590500.922004.455303.45380HepG2SNRNP70
TUT1ENSG00000149016.11900.49450712.771400.337202.468101.98520HepG2SRFBP1
TUT1ENSG00000149016.11418.76600699.38970-0.740009.511608.75320HepG2SRSF1
TUT1ENSG00000149016.11307.82870187.248600.717103.358302.24510HepG2SRSF3
TUT1ENSG00000149016.11538.96840406.166100.408003.634902.93540HepG2SRSF5
TUT1ENSG00000149016.11394.22700299.136000.398102.449801.79200HepG2SRSF7
TUT1ENSG00000149016.11425.93780279.053200.610003.328801.97840HepG2STAU1
TUT1ENSG00000149016.11592.60800461.884200.359403.435302.75630HepG2SUCLG1
TUT1ENSG00000149016.11449.91400282.115100.673305.217103.94670HepG2SUPT6H
TUT1ENSG00000149016.11532.95830286.945600.893104.008103.21650HepG2SUPV3L1
TUT1ENSG00000149016.11445.26480628.71290-0.497703.319102.71360HepG2TAF15
TUT1ENSG00000149016.11377.29250283.562500.411902.667302.11110HepG2TRIM56
TUT1ENSG00000149016.11811.97570425.451600.932309.060307.51240HepG2UBE2L3
TUT1ENSG00000149016.111208.06280902.478100.420603.536102.79410K562AKAP8L
TUT1ENSG00000149016.111216.87580946.882700.361803.580202.52970K562ATP5C1
TUT1ENSG00000149016.11332.65410623.75250-0.907005.779702.78470K562DDX55
TUT1ENSG00000149016.111235.62700971.244100.347203.508402.50510K562DKC1
TUT1ENSG00000149016.11954.20990674.430200.500503.707602.63840K562EFTUD2
TUT1ENSG00000149016.111318.009101674.38470-0.345304.282803.12190K562EIF4G2
TUT1ENSG00000149016.11318.64800641.06090-1.0085010.500408.13780K562FKBP4
TUT1ENSG00000149016.11119.91890317.31890-1.4039010.993809.39630K562G3BP2
TUT1ENSG00000149016.11503.66670738.64280-0.552404.801404.03540K562HNRNPC
TUT1ENSG00000149016.111418.963701039.718400.448502.958101.86160K562HNRNPL
TUT1ENSG00000149016.11882.52020572.996100.623002.430701.48740K562IGF2BP2
TUT1ENSG00000149016.11804.16960601.666800.418402.059401.32960K562MAGOH
TUT1ENSG00000149016.11823.92390600.365600.456602.940001.98500K562MATR3
TUT1ENSG00000149016.11880.55750625.547400.493202.097601.38720K562PPIG
TUT1ENSG00000149016.11850.93810662.253600.361602.621301.74520K562PSIP1
TUT1ENSG00000149016.11956.31130584.596500.709902.915302.23630K562PTBP1
TUT1ENSG00000149016.111532.376801943.26670-0.342703.810002.53780K562PUM1
TUT1ENSG00000149016.11725.99840895.13960-0.302101.783801.32880K562PUS1
TUT1ENSG00000149016.111072.38710872.071800.298202.347301.79380K562RBM15
TUT1ENSG00000149016.11755.79340604.138400.323002.222201.33700K562RCC2
TUT1ENSG00000149016.11847.20220589.661100.522703.213102.02580K562NELFE
TUT1ENSG00000149016.11650.96920862.24360-0.405502.950201.45440K562SDAD1
TUT1ENSG00000149016.11570.05540329.760900.789608.960807.37070K562SF3B4
TUT1ENSG00000149016.11268.34080378.77800-0.497302.966001.32540K562SND1
TUT1ENSG00000149016.11826.71420573.158900.528402.198601.55980K562SRSF1
TUT1ENSG00000149016.11776.18320541.452600.519503.149702.01630K562SRSF5
TUT1ENSG00000149016.11845.24520579.946100.543402.804302.09290K562TARDBP
TUT1ENSG00000149016.11947.13730559.457200.759406.696505.33880K562TIA1
TUT1ENSG00000149016.11865.99950549.297200.656704.494603.03970K562TRA2A
TUT1ENSG00000149016.11862.95500676.624800.350802.519301.62340K562TRIM56
TUT1ENSG00000149016.11887.106101129.57120-0.348602.817601.96350K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TUT1 is not available on ENCORE database.





1 RBPs can affect the splicing of TUT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSTUT1ENSG00000149016.11chr11-623425196234371662342519623426016234412862344221-0.256000.000180.05203shorterHepG2AKAP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TUT1 is not avaliable on ENCORE database.