SYNE4

General Information

Gene Name       : SYNE4
Gene ID             : ENSG00000181392.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SYNE4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SYNE4ENSG00000181392.150.590.460.53ENCSR000AEF
HepG2SYNE4ENSG00000181392.1512.346.019.18ENCSR985KAT
K562SYNE4ENSG00000181392.150.200.250.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SYNE4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SYNE4 RNA is bound by 6 proteins.  







eCLIP assay for SYNE4 is not avaliable on ENCORE database.





6 proteins are bound to SYNE4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193649953836499680-5'-UTR,CDS,intron-Distal,intron-Proximal3.282473.87702HepG2NCBP2
chr193649440436494613-CDS,intron-Distal,intron-Proximal5.094057.45424HepG2AQR
chr193649728936497363-CDS,intron-Distal,intron-Proximal4.950555.60100HepG2PRPF8
chr193649619036496255-CDS,intron-Distal,intron-Proximal4.910297.02967HepG2PRPF8
chr193649934136499420-intron-Distal,intron-Proximal3.762203.06140HepG2NKRF
chr193649712036497193-intron-Distal4.157886.24904HepG2PTBP1
chr193649787436497962-intron-Distal,intron-Proximal3.473864.24143HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SYNE4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SYNE4 is not available on ENCORE database.

  • 65 RBPs can affect the levels of SYNE4.  








The Knockdown/knockout RNA-Seq assay for SYNE4 is not available on ENCORE database.





65 RBPs can affect the gene expression of SYNE4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SYNE4ENSG00000181392.1071.53370127.74250-0.836502.805301.72750HepG2AATF
SYNE4ENSG00000181392.10168.22640268.30000-0.673403.656402.97540HepG2ACO1
SYNE4ENSG00000181392.10118.77030412.97410-1.7979018.1222016.88810HepG2AKAP1
SYNE4ENSG00000181392.10162.1294070.638501.198503.350401.51670HepG2APOBEC3C
SYNE4ENSG00000181392.10279.97060168.491300.732503.396502.30550HepG2CCAR1
SYNE4ENSG00000181392.10256.76890113.909101.172507.973606.85780HepG2CPSF6
SYNE4ENSG00000181392.10115.24790214.85110-0.898605.506804.65780HepG2CELF1
SYNE4ENSG00000181392.10336.07530230.998900.540803.997203.13200HepG2DAZAP1
SYNE4ENSG00000181392.10292.65060189.553600.626503.425302.31000HepG2DDX5
SYNE4ENSG00000181392.10210.47630339.89700-0.691403.604802.90740HepG2DDX6
SYNE4ENSG00000181392.10467.02170256.710500.863205.847204.92860HepG2DKC1
SYNE4ENSG00000181392.10175.09260110.176200.668203.046802.31360HepG2DNAJC21
SYNE4ENSG00000181392.10195.93870109.223600.843005.444704.57540HepG2DNAJC2
SYNE4ENSG00000181392.10484.47390326.641600.568603.378702.72780HepG2EIF2S1
SYNE4ENSG00000181392.1077.42140143.71440-0.892403.356102.36540HepG2EIF3D
SYNE4ENSG00000181392.10227.44400323.29480-0.507302.185201.49680HepG2FIP1L1
SYNE4ENSG00000181392.10236.92570351.11310-0.567503.280702.42940HepG2FUBP3
SYNE4ENSG00000181392.10266.39280129.114601.044806.109605.18400HepG2GPKOW
SYNE4ENSG00000181392.10135.3476070.022300.950703.316802.09220HepG2GRSF1
SYNE4ENSG00000181392.10183.07110108.890000.749403.908603.07060HepG2HNRNPF
SYNE4ENSG00000181392.10667.43660123.217402.4373026.0609024.45140HepG2HNRNPLL
SYNE4ENSG00000181392.10149.94700223.03670-0.572802.579201.65950HepG2HNRNPM
SYNE4ENSG00000181392.10291.67380122.913201.2466012.9213011.68980HepG2HNRNPU
SYNE4ENSG00000181392.10196.39540107.225800.873004.928703.98850HepG2IGF2BP1
SYNE4ENSG00000181392.10592.47210343.411400.786706.625205.62150HepG2IGF2BP2
SYNE4ENSG00000181392.10205.5676073.741301.479008.467606.09850HepG2ILF3
SYNE4ENSG00000181392.10160.9003072.115201.157705.468403.71380HepG2KHDRBS1
SYNE4ENSG00000181392.10228.64320366.45960-0.680603.664402.94760HepG2MATR3
SYNE4ENSG00000181392.10209.09910125.688100.734202.441901.53610HepG2MTPAP
SYNE4ENSG00000181392.10230.58850109.263201.077406.136505.04840HepG2NSUN2
SYNE4ENSG00000181392.10460.93930333.927200.464902.479701.79270HepG2PABPC4
SYNE4ENSG00000181392.10196.21510109.627600.839704.891903.94060HepG2PPIL4
SYNE4ENSG00000181392.1070.87490118.34920-0.739702.210101.48560HepG2PRPF8
SYNE4ENSG00000181392.10465.42790218.662101.0898012.0126010.88920HepG2PUF60
SYNE4ENSG00000181392.10143.00220232.12550-0.698904.131803.43820HepG2PUM1
SYNE4ENSG00000181392.10366.16830231.952200.658604.756803.88910HepG2PUM2
SYNE4ENSG00000181392.10372.96010273.292300.448503.048702.40990HepG2PUS1
SYNE4ENSG00000181392.1026.55670138.86900-2.3866010.542509.23250HepG2RAVER1
SYNE4ENSG00000181392.10176.2414097.591600.852603.212401.37090HepG2RBM14
SYNE4ENSG00000181392.10243.71540355.47650-0.544603.323702.77040HepG2RBM22
SYNE4ENSG00000181392.10266.70010431.85250-0.695306.159405.40650HepG2NELFE
SYNE4ENSG00000181392.10275.74990402.17010-0.544404.095903.36460HepG2RECQL
SYNE4ENSG00000181392.10194.4781075.992601.355607.400606.10670HepG2RPS3A
SYNE4ENSG00000181392.10166.99200109.455700.609302.651502.01800HepG2SAFB2
SYNE4ENSG00000181392.10137.3049072.163300.927903.120001.46910HepG2SBDS
SYNE4ENSG00000181392.10208.6392096.303401.115302.672101.35160HepG2SF1
SYNE4ENSG00000181392.10228.19230356.71860-0.644503.388302.63950HepG2SF3A3
SYNE4ENSG00000181392.10267.50090404.02910-0.594902.162901.63060HepG2SF3B4
SYNE4ENSG00000181392.10327.14560209.675300.641705.042804.14080HepG2SLBP
SYNE4ENSG00000181392.10242.01290401.50500-0.730306.581905.89990HepG2SRFBP1
SYNE4ENSG00000181392.10127.13410421.69860-1.7299019.5376018.52230HepG2SRSF1
SYNE4ENSG00000181392.10186.44190106.980000.801304.430703.58210HepG2SRSF7
SYNE4ENSG00000181392.10202.67830343.05680-0.759306.830006.03160HepG2SRSF9
SYNE4ENSG00000181392.10557.37130348.614300.676908.038007.25160HepG2SSB
SYNE4ENSG00000181392.10140.2407066.121101.084604.867103.36710HepG2STIP1
SYNE4ENSG00000181392.10321.91260152.832201.074605.517704.61390HepG2SUPV3L1
SYNE4ENSG00000181392.10253.76900348.29330-0.456802.747501.91410HepG2TIA1
SYNE4ENSG00000181392.10165.86230276.53700-0.737503.657002.93890HepG2U2AF1
SYNE4ENSG00000181392.10156.40530305.42850-0.965507.827806.90280HepG2UTP3
SYNE4ENSG00000181392.10156.8475068.069301.204205.714304.14200HepG2XPO5
SYNE4ENSG00000181392.10268.79650150.447500.837202.672301.95970HepG2XRN2
SYNE4ENSG00000181392.10234.13350347.93000-0.571504.492803.83940HepG2ZNF622
SYNE4ENSG00000181392.1026.4739054.27000-1.035602.109901.53630K562AKAP8L
SYNE4ENSG00000181392.102.7151032.32760-3.573706.313604.65580K562HNRNPL
SYNE4ENSG00000181392.1021.8228064.52480-1.564004.694803.44750K562MBNL1
SYNE4ENSG00000181392.1026.9346053.83110-0.999002.107001.62070K562PUS1
SYNE4ENSG00000181392.104.3755027.04970-2.628102.473001.36330K562SF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SYNE4 is not available on ENCORE database.





22 RBPs can affect the splicing of SYNE4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649765136497837-0.213000.000880.05447excludedHepG2RBM22
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.139000.001420.07452excludedHepG2AKAP1
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649945536499695-0.433000.000000.00022excludedHepG2DDX3X
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.237000.000000.00003excludedHepG2DDX3X
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649945536499695-0.303000.000200.01776excludedHepG2NCBP2
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.148000.000130.01308excludedHepG2NCBP2
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649945536499695-0.342000.000430.02219excludedHepG2MATR3
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.180000.000030.00245excludedHepG2MATR3
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649765136497846-0.521000.000000.00000excludedHepG2SRSF1
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.461000.000000.00000excludedHepG2SF3A3
SESYNE4ENSG00000181392.10chr19-364973243649757336496234364963393649945536499695-0.226000.002490.09526excludedHepG2PCBP1
SESYNE4ENSG00000181392.10chr19-364945143649457336494211364944223649623436496339-0.229000.000080.00571excludedHepG2SF3B4
SESYNE4ENSG00000181392.10chr19-3649911836499269364980263649817036499455364996950.311000.000510.09920includedHepG2FUBP3
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.260000.000000.00011includedHepG2TIA1
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.277000.000000.00001includedHepG2IGF2BP3
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.408000.000000.00000includedHepG2SRSF1
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.339000.000000.00000includedHepG2QKI
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.305000.000000.00000includedHepG2TAF15
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.130000.005140.06796includedHepG2G3BP1
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.200000.000010.00052includedHepG2KHSRP
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.162000.000090.00193includedHepG2NCBP2
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.174000.000030.00044includedHepG2SF3B4
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.307000.000050.00172includedHepG2FUBP3
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.224000.004470.04106includedHepG2RBM22
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.187000.000020.00049includedHepG2HNRNPK
RISYNE4ENSG00000181392.10chr19-3649623436497573364962343649633936497324364975730.119000.006050.09709includedHepG2PTBP1
MXESYNE4ENSG00000181392.10chr19-36498026364981703649911836499269364976513649784636499455364996950.302000.005140.074041includedHepG2U2AF1
MXESYNE4ENSG00000181392.10chr19-36497324364975733649765136497846364962343649633936498026364981700.323000.000000.000111includedHepG2MATR3
MXESYNE4ENSG00000181392.10chr19-36497324364975733649766636497846364962343649633936498026364981700.329000.000000.000081includedHepG2MATR3
MXESYNE4ENSG00000181392.10chr19-3649802636498170364991183649926936497651364978463649945536499695-0.280000.002720.062862includedHepG2MATR3
MXESYNE4ENSG00000181392.10chr19-36498026364981703649911836499269364976513649784636499455364996950.296000.000230.030171includedHepG2FUBP3
MXESYNE4ENSG00000181392.10chr19-36497324364975733649765636497846364962343649633936499455364996950.125000.002290.092921includedHepG2SRSF9
MXESYNE4ENSG00000181392.10chr19-36497324364975733649765136497846364962343649633936498026364981700.245000.000170.012911includedHepG2DDX3X
MXESYNE4ENSG00000181392.10chr19-3649802636498170364991183649926936497651364978463649945536499695-0.217000.000610.057392includedHepG2SSB
MXESYNE4ENSG00000181392.10chr19-36497324364975733649765136497846364962343649633936498026364981700.375000.001260.038061includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SYNE4 is not avaliable on ENCORE database.