SETD2

General Information

Gene Name : SETD2
Gene ID : ENSG00000181555.20
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SETD2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SETD2	ENSG00000181555.20	32.97	30.53	31.75	ENCSR000AEF
HepG2	SETD2	ENSG00000181555.20	15.20	21.22	18.21	ENCSR985KAT
K562	SETD2	ENSG00000181555.20	27.92	29.60	28.76	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SETD2 is not avaliable on ENCORE database.

Proteins bound to RNA

SETD2 RNA is bound by 48 proteins.

CanvasJS.com

eCLIP assay for SETD2 is not avaliable on ENCORE database.

48 proteins are bound to SETD2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	47057987	47058068	-	3'-UTR,intron-Distal	7.85727	83.08986	K562	PUM2
chr3	47058129	47058176	-	3'-UTR,intron-Distal,intron-Proximal	4.92061	27.07824	K562	PUM2
chr3	47163149	47163302	-	CDS,intron-Distal	4.93658	24.36039	K562	SAFB2
chr3	47127802	47127861	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.88541	21.85820	K562	AQR
chr3	47058196	47058252	-	3'-UTR,intron-Distal	4.74592	19.70107	K562	PUM2
chr3	47165425	47165596	-	CDS,intron-Distal	4.25644	18.36852	HepG2	IGF2BP1
chr3	47162590	47162693	-	CDS,intron-Distal	3.66379	17.84884	HepG2	HLTF
chr3	47131241	47131356	-	intron-Distal	4.27742	16.35021	K562	PTBP1
chr3	47125460	47125537	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.65782	16.18329	K562	UCHL5
chr3	47125470	47125541	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.30181	15.55920	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 196 entries

eCLIP assay for SETD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SETD2 is not available on ENCORE database.
80 RBPs can affect the levels of SETD2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SETD2 is not available on ENCORE database.

80 RBPs can affect the gene expression of SETD2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SETD2	ENSG00000181555.15	1793.59070	2679.90800	-0.57930	15.99120	14.58170	HepG2	UPF1
SETD2	ENSG00000181555.15	4177.80110	2333.19510	0.84030	15.48260	13.94900	HepG2	U2AF1
SETD2	ENSG00000181555.15	7034.28330	4113.02330	0.77410	14.68090	13.47790	K562	AQR
SETD2	ENSG00000181555.15	3088.45510	2145.17900	0.52570	13.60460	12.72690	HepG2	SRSF1
SETD2	ENSG00000181555.15	1190.48800	1727.53130	-0.53720	12.90360	11.60570	HepG2	DNAJC2
SETD2	ENSG00000181555.15	6782.06810	4878.72110	0.47510	11.51250	10.28300	K562	DDX47
SETD2	ENSG00000181555.15	1537.27770	2132.35470	-0.47210	11.48050	10.19020	HepG2	HNRNPL
SETD2	ENSG00000181555.15	4132.98920	2586.45080	0.67610	11.88440	9.77970	K562	PCBP2
SETD2	ENSG00000181555.15	4776.01210	3585.06680	0.41370	11.16130	9.59500	K562	WDR43
SETD2	ENSG00000181555.15	2074.23320	2935.57280	-0.50110	9.55360	8.72140	HepG2	RBM22
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 87 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SETD2 is not available on ENCORE database.

17 RBPs can affect the splicing of SETD2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	SETD2	ENSG00000181555.15	chr3	-	47142947	47143045			47139444	47139571	47144835	47144906	-0.18200	0.00000	excluded	K562	AQR
SE	SETD2	ENSG00000181555.15	chr3	-	47142947	47143045			47139444	47139571	47144835	47144913	-0.15500	0.00000	excluded	K562	PUS1
SE	SETD2	ENSG00000181555.15	chr3	-	47142947	47143045			47139444	47139571	47144835	47144913	-0.14800	0.00000	excluded	K562	RBM15
SE	SETD2	ENSG00000181555.15	chr3	-	47142947	47143045			47139444	47139571	47144835	47144913	-0.19100	0.00000	excluded	K562	AGGF1
A3SS	SETD2	ENSG00000181555.15	chr3	-	47061249	47061359			47061249	47061330	47079155	47079267	0.12800	0.00000	longer	K562	AQR
A3SS	SETD2	ENSG00000181555.15	chr3	-	47079155	47079333			47079155	47079267	47084050	47084263	0.11700	0.00000	longer	K562	AQR
A3SS	SETD2	ENSG00000181555.15	chr3	-	47139444	47139625			47139444	47139571	47142947	47143171	0.11900	0.00000	longer	K562	AQR
A3SS	SETD2	ENSG00000181555.15	chr3	-	47059127	47059300			47059127	47059229	47061249	47061359	0.05600	0.00000	longer	K562	AQR
A3SS	SETD2	ENSG00000181555.15	chr3	-	47122405	47122573			47122405	47122486	47125209	47125872	-0.40800	0.00053	shorter	K562	U2AF1
MXE	SETD2	ENSG00000181555.15	chr3	-	47087976	47088111	47098310	47098980	47084050	47084190	47103652	47103836	0.19700	0.00005	1included	HepG2	U2AF1

Showing 1 to 10 of 50 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SETD2

General Information

Functions

Localization

Domains (AlphaFold: SETD2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SETD2 is not avaliable on ENCORE database.

48 proteins are bound to SETD2 RNA:

eCLIP assay for SETD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SETD2 is not available on ENCORE database.

80 RBPs can affect the gene expression of SETD2 :

The Knockdown/knockout RNA-Seq assay for SETD2 is not available on ENCORE database.

17 RBPs can affect the splicing of SETD2 :

The Knockdown/knockout RNA-Seq assay for SETD2 is not avaliable on ENCORE database.