PLEKHA7

General Information

Gene Name       : PLEKHA7
Gene ID             : ENSG00000166689.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLEKHA7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHA7ENSG00000166689.151.792.822.30ENCSR000AEF
HepG2PLEKHA7ENSG00000166689.1519.1917.8118.50ENCSR985KAT
K562PLEKHA7ENSG00000166689.150.340.110.23ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHA7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHA7 RNA is bound by 24 proteins.  







eCLIP assay for PLEKHA7 is not avaliable on ENCORE database.





24 proteins are bound to PLEKHA7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr111681068816810830-3'-UTR,CDS,intron-Distal,intron-Proximal3.735746.27819HepG2PPIG
chr111687740316877461-3'-UTR,CDS,intron-Distal4.442335.85497HepG2GRWD1
chr111689264316892702-5'-UTR,CDS,intron-Distal,intron-Proximal4.039585.52342HepG2PPIG
chr111682456516824600-CDS,intron-Distal,intron-Proximal3.824265.24452HepG2PPIG
chr111684788916848081-CDS,intron-Distal,intron-Proximal3.558834.00333HepG2EIF3H
chr111687735616877410-CDS,intron-Distal,intron-Proximal3.826263.57857HepG2BCLAF1
chr111681128116811334-CDS,intron-Distal,intron-Proximal3.083453.13980HepG2PRPF8
chr111681648316816545-CDS,intron-Distal,intron-Proximal4.430964.84481HepG2PPIG
chr111684793716848007-CDS,intron-Distal,intron-Proximal3.323103.73413HepG2PPIG
chr111682472516824785-CDS,intron-Distal,intron-Proximal4.926426.35567HepG2PRPF8
chr111687643416876526-CDS,intron-Distal,intron-Proximal3.430966.54857HepG2PPIG
chr111703568717035745-CDS,intron-Distal,intron-Proximal3.389395.31654HepG2PPIG
chr111682452016824565-CDS,intron-Distal3.324265.60389HepG2PPIG
chr111682323616823336-CDS,intron-Distal3.833507.83545HepG2PPIG
chr111681255716812580-CDS,intron-Distal,intron-Proximal3.474704.22917HepG2PPIG
chr111682452716824596-CDS,intron-Distal3.760346.69386HepG2GRWD1
chr111687269916872760-CDS,intron-Distal,intron-Proximal4.136888.70001HepG2PRPF8
chr111687734916877403-CDS,intron-Distal,intron-Proximal4.091939.56105HepG2PPIG
chr111682328716823362-CDS,intron-Distal3.424065.14253HepG2GRWD1
chr111683830716838379-CDS,intron-Distal,intron-Proximal4.3579411.87912HepG2PRPF8
chr111683859216838713-CDS,intron-Distal4.480306.26332HepG2GRWD1
chr111681242516812459-CDS,intron-Distal,intron-Proximal3.042163.99124HepG2PPIG
chr111682252816822583-CDS,intron-Distal,intron-Proximal3.065883.94979HepG2BCLAF1
chr111681652716816565-CDS,intron-Distal3.728283.14999HepG2GRWD1
chr111682248416822551-CDS,intron-Distal,intron-Proximal5.101237.46483HepG2PRPF8
chr111696617416966256-intron-Distal3.381543.35377HepG2QKI
chr111700872117008817-intron-Distal4.444414.55101HepG2PRPF4
chr111680408016804170-intron-Distal4.326863.37054HepG2XPO5
chr111681628016816368-intron-Distal,intron-Proximal4.594054.62947HepG2AQR
chr111692771116927796-intron-Distal3.811143.03891HepG2PTBP1
chr111702537417025451-intron-Distal3.451714.14896HepG2HNRNPM
chr111699643216996483-intron-Distal4.1911611.50879K562LIN28B
chr111701631117016378-intron-Distal3.530804.51074HepG2RBFOX2
chr111683660516836680-intron-Distal4.669085.04056HepG2RBFOX2
chr111700872417008813-intron-Distal3.688335.89725HepG2FAM120A
chr111701539317015502-intron-Distal5.3223219.46246HepG2QKI
chr111695510316955222-intron-Distal3.844698.28561HepG2QKI
chr111686779816867869-intron-Distal3.935103.41738HepG2PTBP1
chr111693066216930724-intron-Distal3.496283.35377HepG2QKI
chr111703528317035334-intron-Distal4.608423.77801HepG2FKBP4
chr111691391816914040-intron-Distal3.784074.26114HepG2HNRNPL
chr111703504717035171-intron-Distal3.7582512.52393HepG2PRPF4
chr111682316516823213-intron-Distal,intron-Proximal4.683714.35676HepG2PRPF8
chr111699644416996503-intron-Distal3.171808.20394K562YBX3
chr111694742816947487-intron-Distal3.043173.23466HepG2CSTF2T
chr111696721916967276-intron-Distal4.775746.66649HepG2HNRNPK
chr111697319316973263-intron-Distal5.6927311.38012HepG2QKI
chr111689018016890226-intron-Distal4.987834.75034HepG2XPO5
chr111697752216977554-intron-Distal4.034373.18711HepG2ILF3
chr111699492816994980-intron-Distal4.517804.70434HepG2RBFOX2
chr111703495317034998-intron-Distal,intron-Proximal3.194373.72734HepG2CSTF2T
chr111700873317008808-intron-Distal4.243624.09621HepG2PCBP2
chr111683637916836429-intron-Distal4.251084.24431HepG2RBFOX2
chr111697133816971501-intron-Distal4.065043.74583HepG2PTBP1
chr111703504817035125-intron-Distal3.255415.35042HepG2GTF2F1
chr111698987416989930-intron-Distal4.163085.09344HepG2XPO5
chr111697134916971472-intron-Distal4.771195.77028HepG2PCBP2
chr111700870317008794-intron-Distal3.896055.53636HepG2GTF2F1
chr111681634316816397-intron-Distal,intron-Proximal3.959985.64484HepG2PRPF8
chr111694694416946992-intron-Distal4.187413.91243HepG2NKRF
chr111703543017035502-intron-Distal,intron-Proximal3.293954.98502HepG2XRN2
chr111683647316836563-intron-Distal6.3454816.90974HepG2RBFOX2
chr111697750016977522-intron-Distal4.229353.77753HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHA7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHA7 is not available on ENCORE database.

  • 60 RBPs can affect the levels of PLEKHA7.  








The Knockdown/knockout RNA-Seq assay for PLEKHA7 is not available on ENCORE database.





60 RBPs can affect the gene expression of PLEKHA7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHA7ENSG00000166689.10697.51250496.009400.491803.589402.47010HepG2ADAR
PLEKHA7ENSG00000166689.10377.34880782.89460-1.052908.938108.04250HepG2AKAP1
PLEKHA7ENSG00000166689.10478.30380905.05820-0.9201012.0617010.93120HepG2BOP1
PLEKHA7ENSG00000166689.10553.62900805.57850-0.541105.247304.22660HepG2CALR
PLEKHA7ENSG00000166689.10390.77120653.49940-0.741901.970901.33070HepG2CNOT7
PLEKHA7ENSG00000166689.10853.832101108.86350-0.377102.929001.59630HepG2DDX47
PLEKHA7ENSG00000166689.10457.70540607.14070-0.407602.381401.35470HepG2EFTUD2
PLEKHA7ENSG00000166689.10957.74460619.219900.629105.472704.65520HepG2EIF2S1
PLEKHA7ENSG00000166689.10386.38030591.20350-0.613604.245403.14230HepG2EIF3D
PLEKHA7ENSG00000166689.10615.79560774.68630-0.331202.850202.00310HepG2EIF4G1
PLEKHA7ENSG00000166689.10750.84150568.481800.401302.764901.97950HepG2FUBP3
PLEKHA7ENSG00000166689.10929.80970680.226000.450802.991502.06540HepG2G3BP2
PLEKHA7ENSG00000166689.10393.44700654.18360-0.733502.775501.40720HepG2HLTF
PLEKHA7ENSG00000166689.10530.31180721.66950-0.444504.446703.31110HepG2HNRNPA2B1
PLEKHA7ENSG00000166689.10731.38480557.160200.392403.694403.00390HepG2HNRNPU
PLEKHA7ENSG00000166689.10493.99430651.00730-0.398202.268401.65010HepG2IGF2BP2
PLEKHA7ENSG00000166689.10682.43870569.118100.261902.213601.54990HepG2ILF2
PLEKHA7ENSG00000166689.10561.15220745.93890-0.410704.639003.32620HepG2KIF1C
PLEKHA7ENSG00000166689.10764.700501221.43200-0.675605.059103.36700HepG2KRR1
PLEKHA7ENSG00000166689.10537.59940694.72300-0.369901.887601.36130HepG2MATR3
PLEKHA7ENSG00000166689.10379.43570618.75680-0.705503.552502.36490HepG2METAP2
PLEKHA7ENSG00000166689.101213.36990797.008300.606306.301005.19890HepG2NSUN2
PLEKHA7ENSG00000166689.10933.46400779.039200.260802.146101.45750HepG2PRPF4
PLEKHA7ENSG00000166689.10674.01790789.03370-0.227302.013901.49170HepG2PUM1
PLEKHA7ENSG00000166689.10642.01260831.21430-0.372603.995303.28030HepG2PUS1
PLEKHA7ENSG00000166689.10383.35170876.52060-1.1931023.9456022.72190HepG2RBM22
PLEKHA7ENSG00000166689.10669.91050496.166600.433004.440003.65700HepG2SAFB2
PLEKHA7ENSG00000166689.101042.89000712.683300.549209.048507.89410HepG2SLBP
PLEKHA7ENSG00000166689.101249.84090989.975200.336203.740803.18510HepG2SRFBP1
PLEKHA7ENSG00000166689.10781.118601233.03400-0.658605.145803.33670HepG2SUGP2
PLEKHA7ENSG00000166689.10659.73040492.486800.421701.925101.34640HepG2SUPV3L1
PLEKHA7ENSG00000166689.10723.37550546.228600.405104.107403.44780HepG2TRIM56
PLEKHA7ENSG00000166689.101369.30360740.625000.886502.537501.59430HepG2U2AF2
PLEKHA7ENSG00000166689.10835.336301094.36610-0.389704.439803.14930HepG2UTP18
PLEKHA7ENSG00000166689.10727.691801027.92710-0.498306.807905.93900HepG2UTP3
PLEKHA7ENSG00000166689.10594.21300768.81270-0.371703.835303.06660HepG2ZC3H8
PLEKHA7ENSG00000166689.10975.919901170.96730-0.262903.010102.44700HepG2ZNF622
PLEKHA7ENSG00000166689.1090.5199017.140002.400808.423205.51450K562ADAR
PLEKHA7ENSG00000166689.108.0051028.13050-1.813202.480901.55850K562AKAP8
PLEKHA7ENSG00000166689.10154.5076041.772301.8870010.063709.05110K562AQR
PLEKHA7ENSG00000166689.1051.1091016.785301.606302.693101.65650K562CCAR1
PLEKHA7ENSG00000166689.10181.2565047.976401.9175010.220008.16620K562CNOT7
PLEKHA7ENSG00000166689.1060.2596017.941701.747804.162701.84450K562CPSF7
PLEKHA7ENSG00000166689.10125.8473067.280100.903303.690902.55880K562CELF1
PLEKHA7ENSG00000166689.1085.0367040.258201.078703.425402.71140K562DDX47
PLEKHA7ENSG00000166689.1051.3865018.793001.451103.279301.82010K562DHX30
PLEKHA7ENSG00000166689.1087.8737032.192001.448604.378002.73190K562EEF2
PLEKHA7ENSG00000166689.10114.9175054.765901.069104.650903.44570K562EIF4G2
PLEKHA7ENSG00000166689.10103.2776034.300501.590107.126005.46550K562HNRNPA1
PLEKHA7ENSG00000166689.1097.8600044.900801.123902.999101.36310K562HNRNPAB
PLEKHA7ENSG00000166689.10125.3142024.731002.3411011.9462010.77800K562HNRNPC
PLEKHA7ENSG00000166689.1012.9185040.74630-1.657202.852801.90620K562HNRNPM
PLEKHA7ENSG00000166689.1076.2742037.977901.005902.768601.87410K562HNRNPU
PLEKHA7ENSG00000166689.1017.3217067.18230-1.955505.999204.84040K562HSPD1
PLEKHA7ENSG00000166689.1047.2002017.538501.428203.082401.49990K562ILF3
PLEKHA7ENSG00000166689.10130.0583034.607801.9099010.914209.56690K562NSUN2
PLEKHA7ENSG00000166689.10266.2504060.814202.1302010.801309.16180K562PCBP3
PLEKHA7ENSG00000166689.10155.6152046.639801.7382010.692009.16280K562POLR2G
PLEKHA7ENSG00000166689.1095.7100043.702401.130903.112001.48420K562SBDS
PLEKHA7ENSG00000166689.10110.7101042.977801.365005.566303.50480K562SDAD1
PLEKHA7ENSG00000166689.1070.7314018.484001.936006.341204.42920K562SLBP
PLEKHA7ENSG00000166689.1076.4041034.979901.127003.160202.16500K562SRPK2
PLEKHA7ENSG00000166689.10111.0022053.079501.064304.023502.18550K562SRSF9
PLEKHA7ENSG00000166689.1062.3029021.329801.546303.827302.72060K562TIAL1
PLEKHA7ENSG00000166689.1076.4400031.399301.283503.983802.92780K562WDR3
PLEKHA7ENSG00000166689.1075.4256032.648101.208003.780902.80180K562WDR43
PLEKHA7ENSG00000166689.1090.9115047.057000.950002.996202.09290K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHA7 is not available on ENCORE database.





3 RBPs can affect the splicing of PLEKHA7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPLEKHA7ENSG00000166689.10chr11-1680248816802599167998411680056716804300168044430.554000.000300.06523includedHepG2ILF3
SEPLEKHA7ENSG00000166689.10chr11-1680248816802599167998411680056716804300168044430.619000.000280.02968includedHepG2QKI
SEPLEKHA7ENSG00000166689.10chr11-168086561680878416807839168079341681064216810843-0.216000.003730.07104excludedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHA7 is not avaliable on ENCORE database.