NPL

General Information

Gene Name : NPL
Gene ID : ENSG00000135838.13
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: NPL)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	NPL	ENSG00000135838.13	7.60	10.49	9.04	ENCSR000AEF
HepG2	NPL	ENSG00000135838.13	0.92	0.08	0.50	ENCSR985KAT
K562	NPL	ENSG00000135838.13	10.63	12.90	11.77	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for NPL is not avaliable on ENCORE database.

Proteins bound to RNA

NPL RNA is bound by 3 proteins.

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eCLIP assay for NPL is not avaliable on ENCORE database.

3 proteins are bound to NPL RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	182772889	182772984	+	5'-UTR,CDS,intron-Proximal	3.69178	9.84724	K562	PRPF8
chr1	182766692	182766800	+	intron-Distal	5.14856	7.56720	K562	PTBP1
chr1	182781116	182781241	+	intron-Distal,intron-Proximal	4.06024	3.29026	K562	KHDRBS1
chr1	182759121	182759195	+	intron-Distal	3.94217	3.12843	K562	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 4 of 4 entries

eCLIP assay for NPL is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for NPL is not available on ENCORE database.
66 RBPs can affect the levels of NPL.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for NPL is not available on ENCORE database.

66 RBPs can affect the gene expression of NPL :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
NPL	ENSG00000135838.9	787.62160	338.03840	1.22020	25.93330	24.13170	K562	DDX47
NPL	ENSG00000135838.9	602.62780	204.15690	1.56150	18.31800	16.06190	K562	BOP1
NPL	ENSG00000135838.9	565.46920	238.79870	1.24360	18.18180	15.78140	K562	HNRNPA1
NPL	ENSG00000135838.9	505.60110	204.15680	1.30820	16.27840	14.91040	K562	HNRNPC
NPL	ENSG00000135838.9	534.30910	220.86950	1.27440	14.99630	12.91930	K562	FMR1
NPL	ENSG00000135838.9	506.22360	176.96930	1.51620	14.87860	12.56310	K562	KRR1
NPL	ENSG00000135838.9	737.81660	321.84150	1.19680	14.42140	12.55590	K562	PCBP3
NPL	ENSG00000135838.9	519.09150	217.63130	1.25400	14.13510	11.78030	K562	UCHL5
NPL	ENSG00000135838.9	742.22770	268.25180	1.46820	13.55180	11.24780	K562	CNOT7
NPL	ENSG00000135838.9	515.19280	246.86390	1.06130	12.82980	11.16880	K562	POLR2G
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 66 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for NPL is not available on ENCORE database.

6 RBPs can affect the splicing of NPL :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	NPL	ENSG00000135838.9	chr1	+	182775553	182775666			182775279	182775367	182781290	182781348	0.45400	0.00000	0.00052	included	K562	HNRNPK
A5SS	NPL	ENSG00000135838.9	chr1	+	182775279	182775666			182775279	182775367	182781290	182781348	0.48400	0.00000	0.00245	longer	K562	HNRNPK
A5SS	NPL	ENSG00000135838.9	chr1	+	182775279	182775666			182775279	182775367	182781290	182781348	0.32000	0.00011	0.01652	longer	K562	EFTUD2
SE	NPL	ENSG00000135838.9	chr1	+	182764864	182764975			182763490	182763574	182772832	182772906	0.05500	0.00089	0.09627	included	K562	DROSHA
MXE	NPL	ENSG00000135838.9	chr1	+	182787947	182787994	182791177	182791334	182787675	182787824	182794915	182796155	-0.29200	0.00437	0.05020	2included	K562	U2AF2
MXE	NPL	ENSG00000135838.9	chr1	+	182791249	182791334	182794915	182794955	182787947	182787994	182798737	182799519	-0.35000	0.00500	0.06609	2included	K562	SRSF1
SE	NPL	ENSG00000135838.9	chr1	+	182764864	182764975			182763490	182763574	182772832	182772906	0.07400	0.00950	0.07796	included	K562	AQR

Showing 1 to 7 of 7 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

NPL

General Information

Functions

Localization

Domains (AlphaFold: NPL)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for NPL is not avaliable on ENCORE database.

3 proteins are bound to NPL RNA:

eCLIP assay for NPL is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for NPL is not available on ENCORE database.

66 RBPs can affect the gene expression of NPL :

The Knockdown/knockout RNA-Seq assay for NPL is not available on ENCORE database.

6 RBPs can affect the splicing of NPL :

The Knockdown/knockout RNA-Seq assay for NPL is not avaliable on ENCORE database.