MRPL52

General Information

Gene Name       : MRPL52
Gene ID             : ENSG00000172590.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL52)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL52ENSG00000172590.1827.2545.7836.52ENCSR000AEF
HepG2MRPL52ENSG00000172590.18196.68107.20151.94ENCSR985KAT
K562MRPL52ENSG00000172590.1851.6347.7949.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL52 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL52 RNA is bound by 20 proteins.  







eCLIP assay for MRPL52 is not avaliable on ENCORE database.





20 proteins are bound to MRPL52 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr142330346723303533+3'-UTR,CDS5.4739111.16260HepG2LARP4
chr142330262623302655+3'-UTR,CDS,intron-Distal,intron-Proximal3.973485.02854K562PABPC4
chr142330260823302659+3'-UTR,CDS,intron-Distal,intron-Proximal3.642104.75435K562EFTUD2
chr142330351923303559+3'-UTR,CDS,polyA_site3.992987.39807K562PABPC4
chr142330375023303794+3'-UTR3.598774.25556HepG2TIAL1
chr142330376523303809+3'-UTR4.712074.98857K562TIA1
chr142330374923303783+3'-UTR4.184883.89565K562PRPF8
chr142330262523302675+3'-UTR,CDS,intron-Distal,intron-Proximal3.5256913.91621HepG2LARP4
chr142330375523303765+3'-UTR4.435444.48529K562TIA1
chr142330261223302667+3'-UTR,CDS,intron-Distal,intron-Proximal3.3001310.79792HepG2U2AF2
chr142329944523299464+5'-UTR,CDS,intron-Proximal3.012753.50044K562YBX3
chr142329917723299313+5'-UTR,CDS,intron-Distal,intron-Proximal3.0045411.56965HepG2SF3B4
chr142329917223299251+5'-UTR,intron-Distal,intron-Proximal5.3292031.92241HepG2EFTUD2
chr142329925123299309+5'-UTR,CDS,intron-Distal,intron-Proximal4.0378821.78574HepG2EFTUD2
chr142329943423299506+5'-UTR,CDS,intron-Proximal4.2854230.01162HepG2PRPF8
chr142329944023299464+5'-UTR,CDS,intron-Proximal3.7692010.88022HepG2LARP4
chr142329925923299322+5'-UTR,CDS,intron-Distal,intron-Proximal3.4928516.12500HepG2RPS3
chr142329931623299369+5'-UTR,CDS,intron-Proximal3.168838.55730HepG2PRPF8
chr142329946223299532+5'-UTR,CDS,intron-Proximal4.376004.62947HepG2AQR
chr142329925623299305+5'-UTR,CDS,intron-Distal,intron-Proximal3.5999019.75858K562DDX3X
chr142329925523299317+5'-UTR,CDS,intron-Distal,intron-Proximal3.4182310.86592HepG2DDX3X
chr142329911423299150+5'-UTR,CDS,intron-Proximal3.157849.92071K562DDX3X
chr142329939423299464+5'-UTR,CDS,intron-Proximal3.1522315.06047K562DDX3X
chr142329930523299320+5'-UTR,CDS,intron-Proximal3.431299.50106K562DDX3X
chr142329940923299440+5'-UTR,CDS3.239879.63624HepG2LARP4
chr142329914523299246+5'-UTR,CDS,intron-Proximal4.6037217.68873HepG2PRPF8
chr142329930923299375+5'-UTR,CDS,intron-Proximal5.4452720.19318HepG2EFTUD2
chr142329918823299314+5'-UTR,CDS,intron-Distal,intron-Proximal5.4434710.68826HepG2AQR
chr142330336323303414+CDS,intron-Proximal3.114914.87883K562BUD13
chr142330268323302731+CDS,intron-Distal,intron-Proximal5.3982722.46178HepG2PRPF8
chr142330339823303448+CDS3.013194.22109HepG2LIN28B
chr142330266023302683+CDS,intron-Distal4.5283610.64040HepG2PRPF8
chr142330339523303479+CDS3.159436.11586HepG2G3BP1
chr142330337923303417+CDS,intron-Proximal3.2730213.37694HepG2LARP4
chr142330341723303467+CDS3.2956718.57187HepG2LARP4
chr142330332823303401+CDS,intron-Proximal3.040759.24262HepG2SF3A3
chr142330267023302692+CDS,intron-Distal,intron-Proximal4.692377.71026K562PABPC4
chr142330341223303480+CDS5.9622817.53659K562PABPC4
chr142330336923303454+CDS,intron-Proximal4.899366.12579HepG2PABPN1
chr142330338023303408+CDS,intron-Proximal4.244478.41415K562PABPC4
chr142330337623303477+CDS,intron-Proximal3.381326.77374K562DDX55
chr142329949423299584+intron-Distal,intron-Proximal4.1381019.65936HepG2EFTUD2
chr142329950023299564+intron-Distal,intron-Proximal5.364586.55845K562RBM22
chr142330284023302894+intron-Distal3.536605.35725HepG2HNRNPC
chr142329950123299533+intron-Proximal4.4575426.26812HepG2RBM22
chr142329933923299388+intron-Proximal4.347575.95597K562EFTUD2
chr142329933523299389+intron-Proximal5.081716.39664HepG2SF3B4
chr142329950423299558+intron-Proximal3.453907.64390K562EFTUD2
chr142329953323299549+intron-Proximal4.9080620.76702HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL52 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL52 is not available on ENCORE database.

  • 63 RBPs can affect the levels of MRPL52.  








The Knockdown/knockout RNA-Seq assay for MRPL52 is not available on ENCORE database.





63 RBPs can affect the gene expression of MRPL52 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL52ENSG00000172590.141145.83390943.294300.280502.996302.36780HepG2ACO1
MRPL52ENSG00000172590.142341.225201249.602200.9057011.3674010.36020HepG2AKAP1
MRPL52ENSG00000172590.141192.31480727.138400.713404.288803.12120HepG2BCCIP
MRPL52ENSG00000172590.14805.18420406.214700.987008.427207.45180HepG2BOP1
MRPL52ENSG00000172590.141108.71160654.323000.760705.093004.05090HepG2CNOT7
MRPL52ENSG00000172590.141283.198901110.852300.208002.228501.55260HepG2DAZAP1
MRPL52ENSG00000172590.141906.055801196.941200.671107.367206.39150HepG2DDX3X
MRPL52ENSG00000172590.14659.99250860.85550-0.383302.681401.40290HepG2DDX47
MRPL52ENSG00000172590.14994.82640714.973100.476502.530701.78680HepG2DDX55
MRPL52ENSG00000172590.141584.394201028.393100.623405.573704.72380HepG2DDX6
MRPL52ENSG00000172590.14684.06100455.315800.587208.134407.08870HepG2DNAJC2
MRPL52ENSG00000172590.141266.22120921.846700.457804.676703.59510HepG2EWSR1
MRPL52ENSG00000172590.14594.64000914.78100-0.621406.679405.48880HepG2FUBP3
MRPL52ENSG00000172590.14831.337901020.94160-0.296402.656601.73880HepG2HNRNPA2B1
MRPL52ENSG00000172590.14749.09690540.298900.471302.718701.33050HepG2HNRNPAB
MRPL52ENSG00000172590.14731.57330515.854000.503903.753102.95500HepG2HNRNPC
MRPL52ENSG00000172590.141161.472201011.878500.198801.953001.37460HepG2HNRNPL
MRPL52ENSG00000172590.14723.27540512.443200.497102.802802.19130HepG2HNRNPU
MRPL52ENSG00000172590.14691.92520523.443200.402504.447603.53760HepG2ILF2
MRPL52ENSG00000172590.14836.30760602.139500.473803.371402.11950HepG2LARP7
MRPL52ENSG00000172590.14839.80280632.012100.410002.527701.37200HepG2LIN28B
MRPL52ENSG00000172590.14427.07740235.763500.857104.883303.00460HepG2NOLC1
MRPL52ENSG00000172590.141381.342101073.562000.363604.849904.08180HepG2PCBP1
MRPL52ENSG00000172590.14668.06720457.057800.547505.799904.76460HepG2PPIL4
MRPL52ENSG00000172590.141318.975201116.260400.240602.441801.87790HepG2PUM1
MRPL52ENSG00000172590.142050.088601431.483700.518104.836604.19960HepG2RBM22
MRPL52ENSG00000172590.141066.06780726.110900.553904.192702.95460HepG2RBM27
MRPL52ENSG00000172590.141148.77750669.617100.778608.429507.08470HepG2RPS2
MRPL52ENSG00000172590.141005.85900657.036400.614304.226803.23770HepG2RPS3A
MRPL52ENSG00000172590.141127.84070683.587100.722305.809404.24020HepG2RPS5
MRPL52ENSG00000172590.14841.46920456.351400.8827017.4326016.01390HepG2SAFB2
MRPL52ENSG00000172590.14908.73610618.714300.554503.725102.21060HepG2SART3
MRPL52ENSG00000172590.14758.30050532.179600.510806.557905.63260HepG2SMN1
MRPL52ENSG00000172590.142282.920301616.739800.497705.823505.17090HepG2SRFBP1
MRPL52ENSG00000172590.14966.819001187.11160-0.296102.966202.48090HepG2SRSF1
MRPL52ENSG00000172590.141423.576301038.253100.455307.285106.33550HepG2SRSF5
MRPL52ENSG00000172590.14804.53990965.80930-0.263602.345401.82910HepG2SRSF9
MRPL52ENSG00000172590.141610.295001180.754700.447508.588807.59370HepG2SUCLG1
MRPL52ENSG00000172590.14957.08450711.674700.427302.064001.46720HepG2SUPV3L1
MRPL52ENSG00000172590.14702.84940476.967900.559202.358701.43250HepG2TFIP11
MRPL52ENSG00000172590.14958.43220502.386300.931807.361806.51840HepG2TRIM56
MRPL52ENSG00000172590.141376.108001027.331500.421604.398303.26530HepG2TUFM
MRPL52ENSG00000172590.14591.74310420.360300.493202.574701.84340HepG2UCHL5
MRPL52ENSG00000172590.141086.27030734.405300.564608.789807.82000HepG2UTP3
MRPL52ENSG00000172590.14901.01420588.508900.614404.078102.74310HepG2XPO5
MRPL52ENSG00000172590.141124.50090700.567800.682605.776704.74060HepG2XRN2
MRPL52ENSG00000172590.141102.65030907.444100.281002.931702.34910K562AGGF1
MRPL52ENSG00000172590.141301.41690944.255400.462704.797403.92990K562AKAP8L
MRPL52ENSG00000172590.14982.316301434.58450-0.546405.082804.32990K562AQR
MRPL52ENSG00000172590.141196.47970990.786500.272002.160601.36060K562ATP5C1
MRPL52ENSG00000172590.14826.29900670.068000.302302.524701.60950K562BCLAF1
MRPL52ENSG00000172590.141202.94600913.598100.396804.323803.53510K562DDX47
MRPL52ENSG00000172590.141279.57110991.604700.367704.220403.36020K562EIF2S2
MRPL52ENSG00000172590.14323.63590506.53930-0.646303.862302.99470K562G3BP2
MRPL52ENSG00000172590.14317.72480544.32100-0.776706.226505.36540K562HNRNPC
MRPL52ENSG00000172590.14364.22550527.63280-0.534702.760901.37490K562LARP7
MRPL52ENSG00000172590.14660.13030807.01690-0.289802.181801.45900K562MTPAP
MRPL52ENSG00000172590.14533.72080684.86710-0.359702.565801.38170K562NCBP2
MRPL52ENSG00000172590.14490.08800704.30180-0.523203.569502.62440K562PCBP3
MRPL52ENSG00000172590.14928.32720638.899500.538904.969703.81820K562PPIG
MRPL52ENSG00000172590.14714.10360539.970200.403202.504801.79100K562PRPF8
MRPL52ENSG00000172590.141321.02580936.308700.496504.667403.98590K562PUS1
MRPL52ENSG00000172590.141147.28280912.402400.330403.250702.61630K562RBM15
MRPL52ENSG00000172590.14740.34190550.015200.428602.361001.60940K562RPS19
MRPL52ENSG00000172590.14933.59280590.395100.661007.875206.69150K562SRSF1
MRPL52ENSG00000172590.14439.76970614.92500-0.483703.241601.59620K562SRSF9
MRPL52ENSG00000172590.14612.77130813.44010-0.408702.461901.63430K562WDR3
MRPL52ENSG00000172590.141217.700001616.07050-0.408303.927802.86770K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL52 is not available on ENCORE database.





23 RBPs can affect the splicing of MRPL52 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL52ENSG00000172590.14chr14+233026262330269823299395232994632330338023303555-0.096000.000540.01259excludedK562SRSF1
SEMRPL52ENSG00000172590.14chr14+233026262330269123299395232994632330338023303555-0.145000.000000.00000excludedHepG2U2AF1
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330262623302691-0.084000.000000.00000excludedK562AKAP8L
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323302626233026910.124000.000000.00000includedHepG2U2AF2
SEMRPL52ENSG00000172590.14chr14+233026262330269123299395232994632330338023303555-0.249000.000000.00000excludedHepG2U2AF2
SEMRPL52ENSG00000172590.14chr14+233026262330269123299395232994632330338023303555-0.052000.000030.00341excludedHepG2AKAP1
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323302626233026770.083000.000000.00012includedK562AQR
SEMRPL52ENSG00000172590.14chr14+233026262330269823299395232994632330338023303555-0.052000.000250.00381excludedK562AQR
SEMRPL52ENSG00000172590.14chr14+233026262330269823299375232994632330338023303555-0.051000.001990.02991excludedK562PUS1
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323302626233026910.059000.000060.02071includedK562MTPAP
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330262623302691-0.051000.002380.06484excludedK562UTP18
SEMRPL52ENSG00000172590.14chr14+233026262330269123299395232994632330338023303555-0.124000.000000.00000excludedK562U2AF2
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330262623302691-0.067000.000160.00918excludedK562TARDBP
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330262623302691-0.069000.000010.00037excludedK562AGGF1
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330338023304186-0.378000.002560.09103excludedK562HNRNPK
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323303380233041860.304000.001070.04056includedHepG2HNRNPC
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323302626233026910.058000.000000.00000includedHepG2FUS
SEMRPL52ENSG00000172590.14chr14+233001722330024623299395232994632330262623302691-0.078000.000330.06019excludedK562NPM1
SEMRPL52ENSG00000172590.14chr14+2330017223300246232993952329946323302626233026910.510000.000000.00000includedK562HNRNPC
A5SSMRPL52ENSG00000172590.14chr14+232993952329954823299395232994632330017223300246-0.126000.000040.00511shorterK562HNRNPC
A5SSMRPL52ENSG00000172590.14chr14+2329909523299153232990952329914923299261232993190.074000.000600.04771longerHepG2SF3A3
A5SSMRPL52ENSG00000172590.14chr14+233026262330269823302626233026912330338023303555-0.074000.000250.09714shorterK562NPM1
A5SSMRPL52ENSG00000172590.14chr14+233026262330269823302626233026912330338023303555-0.071000.000170.04086shorterK562DROSHA
RIMRPL52ENSG00000172590.14chr14+2329911423299319232991142329915323299261232993190.060000.002880.09834includedHepG2BCCIP
RIMRPL52ENSG00000172590.14chr14+2329909523299319232990952329914923299261232993190.104000.006120.05855includedHepG2SF3A3
RIMRPL52ENSG00000172590.14chr14+2329909523299319232990952329914923299261232993190.118000.002330.06528includedHepG2MATR3
RIMRPL52ENSG00000172590.14chr14+2329909523299319232990952329914923299261232993190.108000.010960.08542includedHepG2U2AF1
RIMRPL52ENSG00000172590.14chr14+2329910323299319232991032329915323299258232993190.117000.009160.08023includedHepG2NCBP2
RIMRPL52ENSG00000172590.14chr14+2329909523299319232990952329914923299261232993190.145000.001370.01214includedHepG2SF3B4
RIMRPL52ENSG00000172590.14chr14+2329909523299319232990952329914923299261232993190.152000.000000.00013includedHepG2RBM22
RIMRPL52ENSG00000172590.14chr14+2329909123299261232990912329914923299258232992610.188000.000000.00000includedK562AQR
MXEMRPL52ENSG00000172590.14chr14+23300172233002172330262623302698232993952329946323303380233035550.065000.000370.011971includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL52 is not avaliable on ENCORE database.