HSF2

General Information

Gene Name       : HSF2
Gene ID             : ENSG00000025156.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HSF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HSF2ENSG00000025156.1217.7611.4114.59ENCSR000AEF
HepG2HSF2ENSG00000025156.1217.2819.1418.21ENCSR985KAT
K562HSF2ENSG00000025156.1219.0019.6719.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HSF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HSF2 RNA is bound by 16 proteins.  







eCLIP assay for HSF2 is not avaliable on ENCORE database.





16 proteins are bound to HSF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6122753473122753562+3'-UTR3.369824.00685K562TIA1
chr6122753346122753390+3'-UTR,CDS3.684796.24385K562PUM2
chr6122720798122720965+5'-UTR,CDS3.629963.59926K562DDX3X
chr6122733503122733549+CDS,intron-Proximal4.544573.07225K562U2AF1
chr6122743287122743362+CDS,intron-Proximal4.580575.08762K562U2AF2
chr6122733502122733549+CDS,intron-Proximal5.366566.81110K562U2AF2
chr6122743273122743348+CDS,intron-Proximal3.756405.02403K562SF3B4
chr6122733902122733956+CDS,intron-Proximal5.432628.34710K562AQR
chr6122734664122734712+CDS,intron-Proximal3.590904.77019K562BUD13
chr6122737350122737437+CDS,intron-Proximal3.443473.39008HepG2AQR
chr6122737431122737528+CDS,intron-Proximal4.603134.22101K562PRPF8
chr6122744763122744856+CDS,intron-Proximal5.665446.35567HepG2PRPF8
chr6122746798122746874+intron-Distal4.668266.36200HepG2PTBP1
chr6122734794122734908+intron-Distal,intron-Proximal4.1999912.56301K562AQR
chr6122746217122746281+intron-Distal4.789865.43236K562PTBP1
chr6122751511122751604+intron-Distal3.758274.02241K562EXOSC5
chr6122746874122746944+intron-Distal3.546304.78196HepG2PTBP1
chr6122746767122746861+intron-Distal3.633213.39827HepG2MATR3
chr6122745475122745606+intron-Distal3.676234.26619K562MATR3
chr6122746559122746664+intron-Distal6.5485815.72184K562QKI
chr6122746590122746706+intron-Distal6.3916918.28830HepG2QKI
chr6122750600122750660+intron-Distal4.431025.12361K562EXOSC5
chr6122748225122748389+intron-Distal3.078263.04623HepG2KHSRP
chr6122749875122749968+intron-Distal5.4475210.34146K562EXOSC5
chr6122746174122746280+intron-Distal3.239213.45713HepG2PTBP1
chr6122734829122734950+intron-Distal,intron-Proximal3.887059.76669K562PRPF8
chr6122746886122746949+intron-Distal3.478284.28254HepG2MATR3
chr6122746866122746943+intron-Distal4.712053.23532K562MATR3
chr6122748320122748418+intron-Distal6.3308317.14892K562CPSF6
chr6122745398122745460+intron-Distal4.065047.22843HepG2PTBP1
chr6122733183122733302+intron-Distal3.166263.07751K562KHSRP
chr6122746711122746806+intron-Distal5.163297.97897HepG2QKI
chr6122746907122746948+intron-Distal4.865514.90095K562PTBP1
chr6122746664122746758+intron-Distal5.4170614.05565K562QKI
chr6122750070122750174+intron-Distal5.597309.68086K562EXOSC5
chr6122745407122745464+intron-Distal5.360817.91717K562PTBP1
chr6122737447122737540+intron-Proximal3.771574.30679K562KHSRP
chr6122741407122741452+intron-Proximal4.442343.62536K562AQR
chr6122734825122734876+intron-Proximal3.133474.06992K562GPKOW
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HSF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HSF2 is not available on ENCORE database.

  • 51 RBPs can affect the levels of HSF2.  








The Knockdown/knockout RNA-Seq assay for HSF2 is not available on ENCORE database.





51 RBPs can affect the gene expression of HSF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HSF2ENSG00000025156.8508.76970676.50140-0.411103.554502.84440HepG2CELF1
HSF2ENSG00000025156.8404.65980593.14800-0.551702.148501.59720HepG2DDX6
HSF2ENSG00000025156.8345.13830433.10640-0.327502.213401.61720HepG2DNAJC2
HSF2ENSG00000025156.8287.54320570.39830-0.988205.204904.40650HepG2EIF2S1
HSF2ENSG00000025156.8440.10610630.44950-0.518502.092701.53440HepG2EIF4A3
HSF2ENSG00000025156.8570.51350873.22640-0.614108.217507.27590HepG2ETF1
HSF2ENSG00000025156.8416.93630589.96120-0.500801.999801.43090HepG2G3BP1
HSF2ENSG00000025156.8331.38010501.72810-0.598403.603702.88190HepG2GPKOW
HSF2ENSG00000025156.8413.81990597.04620-0.528802.466001.80460HepG2HNRNPK
HSF2ENSG00000025156.8528.20170662.60080-0.327102.890402.20410HepG2HNRNPL
HSF2ENSG00000025156.8237.49070478.80710-1.011608.907607.84900HepG2HNRNPLL
HSF2ENSG00000025156.8123.34720366.36510-1.5706018.2682016.19420HepG2HNRNPM
HSF2ENSG00000025156.8336.49640599.73490-0.833704.036603.23510HepG2IGF2BP2
HSF2ENSG00000025156.8420.10220639.64390-0.606502.745902.11690HepG2MATR3
HSF2ENSG00000025156.8237.05240371.14900-0.646802.421701.40560HepG2NONO
HSF2ENSG00000025156.8410.04310583.26540-0.508402.036501.40880HepG2PABPC4
HSF2ENSG00000025156.8500.63100688.53280-0.459803.474602.81670HepG2PUF60
HSF2ENSG00000025156.8796.11910572.259500.476202.747002.07510HepG2SF3A3
HSF2ENSG00000025156.8482.44020660.20080-0.452604.644503.77190HepG2SLBP
HSF2ENSG00000025156.8995.06250824.343400.271402.491702.00740HepG2SRFBP1
HSF2ENSG00000025156.8790.94060636.128800.314202.572802.11240HepG2SRSF1
HSF2ENSG00000025156.8447.52250679.82880-0.603207.053706.11820HepG2SRSF5
HSF2ENSG00000025156.8384.20990517.52810-0.429703.606302.99480HepG2SRSF9
HSF2ENSG00000025156.8211.66450402.37430-0.926806.100805.15480HepG2SUPV3L1
HSF2ENSG00000025156.8302.64440473.72860-0.646405.634804.97040HepG2TIAL1
HSF2ENSG00000025156.8283.99510477.91400-0.750908.692007.77960HepG2TRIM56
HSF2ENSG00000025156.8519.55550672.67150-0.372602.490901.66530HepG2TUFM
HSF2ENSG00000025156.8594.12890454.228500.387301.999101.45580HepG2U2AF1
HSF2ENSG00000025156.8498.87660712.01490-0.513203.184302.28640HepG2UBE2L3
HSF2ENSG00000025156.8336.38320507.50820-0.593305.905204.94610HepG2UPF1
HSF2ENSG00000025156.8460.54410558.15970-0.277302.004501.51860HepG2ZNF622
HSF2ENSG00000025156.81928.942801047.134800.8813026.9050025.24830K562AGGF1
HSF2ENSG00000025156.81783.539801089.605200.7108010.833609.42370K562AKAP8L
HSF2ENSG00000025156.81447.944201143.284700.340702.712501.80860K562ATP5C1
HSF2ENSG00000025156.8691.91800849.62140-0.296202.041301.35940K562CPSF6
HSF2ENSG00000025156.81565.063101172.405500.416603.222402.26820K562DKC1
HSF2ENSG00000025156.8561.47100828.59320-0.561506.907705.84640K562EIF2S2
HSF2ENSG00000025156.8540.37330732.75270-0.439402.814501.89260K562FTO
HSF2ENSG00000025156.81352.84780894.212600.597202.911502.18290K562G3BP2
HSF2ENSG00000025156.8632.78970811.16750-0.358302.405901.66320K562GPKOW
HSF2ENSG00000025156.81646.449001022.937700.686503.096301.78450K562HNRNPA2B1
HSF2ENSG00000025156.8522.62030770.20710-0.559505.081904.29440K562HNRNPC
HSF2ENSG00000025156.8180.00340721.26310-2.0025032.4914029.02350K562HNRNPM
HSF2ENSG00000025156.81216.42570956.089900.347303.554602.54080K562HNRNPU
HSF2ENSG00000025156.81835.527401156.294400.666607.137405.66370K562KIF1C
HSF2ENSG00000025156.8795.944401022.08880-0.360802.233401.41200K562MATR3
HSF2ENSG00000025156.81894.109201295.348700.548107.013505.44150K562MBNL1
HSF2ENSG00000025156.81790.66410907.949900.979705.011903.70790K562NAA15
HSF2ENSG00000025156.83121.595801080.489401.5305044.0041041.76800K562PUS1
HSF2ENSG00000025156.81989.123101052.857000.9177015.5785014.15450K562RBM15
HSF2ENSG00000025156.8723.96410954.30060-0.398502.158301.42080K562RBM22
HSF2ENSG00000025156.8668.73500987.19360-0.561904.620503.70020K562TARDBP
HSF2ENSG00000025156.8743.61340952.22640-0.356802.402401.64600K562TIA1
HSF2ENSG00000025156.8629.98630939.20190-0.576102.837801.62130K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HSF2 is not available on ENCORE database.





13 RBPs can affect the splicing of HSF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.301000.000210.02474includedHepG2G3BP1
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.577000.000000.00000includedK562SRSF1
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752659-0.192000.000030.00206excludedK562AKAP8L
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.249000.000450.01387includedHepG2HNRNPK
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752813-0.172000.000060.00108excludedK562AQR
SEHSF2ENSG00000025156.8chr6+122737365122737441122734669122734794122740312122740354-0.061000.000840.01058excludedK562AQR
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.250000.000280.01408includedK562FXR1
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752659-0.195000.000010.00045excludedK562PUS1
SEHSF2ENSG00000025156.8chr6+122737365122737441122733781122733909122740312122740374-0.093000.000000.00017excludedK562PUS1
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752659-0.197000.000690.09747excludedK562NSUN2
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.264000.000140.05900includedK562KHSRP
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752659-0.166000.000070.00211excludedK562U2AF2
SEHSF2ENSG00000025156.8chr6+122749047122749101122744725122744831122752574122752659-0.160000.000600.01826excludedK562RBM15
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.333000.000250.06040includedHepG2EIF3D
SEHSF2ENSG00000025156.8chr6+1227490471227491011227447251227448311227525741227526590.445000.000000.00016includedK562HNRNPC
A3SSHSF2ENSG00000025156.8chr6+1227530171227531371227530691227531371227525741227526590.075000.000000.00000longerK562AQR
A3SSHSF2ENSG00000025156.8chr6+1227337551227339091227337811227339091227335171227336260.209000.000000.00000longerK562AQR
A5SSHSF2ENSG00000025156.8chr6+1227432941227434661227432941227434431227438621227441020.114000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HSF2 is not avaliable on ENCORE database.