DERL1

General Information

Gene Name       : DERL1
Gene ID             : ENSG00000136986.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DERL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DERL1ENSG00000136986.930.0325.7827.91ENCSR000AEF
HepG2DERL1ENSG00000136986.922.9231.6927.30ENCSR985KAT
K562DERL1ENSG00000136986.925.4925.2125.35ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DERL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DERL1 RNA is bound by 20 proteins.  







eCLIP assay for DERL1 is not avaliable on ENCORE database.





20 proteins are bound to DERL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8124026060124026127-3'-UTR,intron-Distal3.099813.27682HepG2LARP4
chr8124027432124027495-3'-UTR,intron-Distal4.047013.98716K562IGF2BP1
chr8124026770124026841-3'-UTR,intron-Distal5.450649.88915K562LIN28B
chr8124025624124025661-3'-UTR,intron-Distal4.079357.35577K562PUM2
chr8124027239124027316-3'-UTR,intron-Distal,intron-Proximal3.192563.82829K562IGF2BP2
chr8124027054124027102-3'-UTR,intron-Distal4.378975.29045K562IGF2BP1
chr8124026403124026449-3'-UTR,intron-Distal4.790476.41561K562TIA1
chr8124027102124027149-3'-UTR,intron-Distal4.104403.98311K562IGF2BP1
chr8124027098124027156-3'-UTR,intron-Distal4.238613.76295K562IGF2BP2
chr8124026071124026170-3'-UTR,intron-Distal3.973185.99105K562UPF1
chr8124025954124026015-3'-UTR,intron-Distal3.301444.76534K562PUM2
chr8124027536124027664-3'-UTR,intron-Distal,intron-Proximal4.383835.82137K562YBX3
chr8124027656124027734-3'-UTR,CDS,intron-Distal,intron-Proximal3.630968.97247HepG2SND1
chr8124027085124027193-3'-UTR,intron-Distal3.448734.85120HepG2IGF2BP1
chr8124026841124026873-3'-UTR,intron-Distal5.042109.44026K562LIN28B
chr8124026046124026121-3'-UTR,intron-Distal4.8744821.30394K562PABPC4
chr8124027157124027214-3'-UTR,intron-Distal3.260983.34065K562IGF2BP1
chr8124027249124027321-3'-UTR,intron-Distal,intron-Proximal4.710065.76537HepG2PCBP2
chr8124027659124027706-3'-UTR,CDS,intron-Distal,intron-Proximal3.362914.22460K562RBM15
chr8124027337124027432-3'-UTR,intron-Distal,intron-Proximal3.679005.23915K562IGF2BP1
chr8124054404124054489-5'-UTR,intron-Distal,intron-Proximal3.821416.59200K562DDX3X
chr8124054451124054530-5'-UTR,intron-Distal,intron-Proximal4.467718.54751HepG2DDX3X
chr8124037263124037291-5'-UTR,CDS,intron-Distal,intron-Proximal4.335496.47873K562SND1
chr8124037238124037263-5'-UTR,CDS,intron-Distal3.550956.49527K562SND1
chr8124054353124054444-5'-UTR,CDS,intron-Distal,intron-Proximal3.560496.67587HepG2DDX3X
chr8124031513124031546-CDS,intron-Distal,intron-Proximal3.276464.50206K562SND1
chr8124027700124027771-CDS,intron-Distal3.491054.22960K562SND1
chr8124027695124027784-CDS,intron-Distal4.333163.76295K562LIN28B
chr8124027761124027852-CDS,intron-Distal3.847873.00614K562U2AF2
chr8124035900124035975-CDS,intron-Distal,intron-Proximal3.732914.88100K562AQR
chr8124027734124027778-CDS,intron-Distal4.142469.51650HepG2SND1
chr8124034949124035011-CDS,intron-Distal3.902413.02397HepG2SND1
chr8124034869124034998-CDS,intron-Distal,intron-Proximal5.027023.70131HepG2PRPF8
chr8124035952124035955-CDS,intron-Distal,intron-Proximal4.093393.54264K562SND1
chr8124034812124034933-CDS,intron-Distal,intron-Proximal5.2949418.31991K562PRPF8
chr8124035955124035980-CDS,intron-Distal,intron-Proximal3.533746.82656K562SND1
chr8124054165124054222-CDS,intron-Distal4.053368.87031K562PRPF8
chr8124027783124027827-CDS,intron-Distal4.6409217.28129HepG2SND1
chr8124054164124054244-CDS,intron-Distal3.773998.16617HepG2PRPF8
chr8124031432124031505-CDS,intron-Distal,intron-Proximal3.156928.40720K562SND1
chr8124034923124035021-CDS,intron-Distal,intron-Proximal4.3623412.29334K562SND1
chr8124033685124033740-CDS,intron-Distal,intron-Proximal4.0941610.85424K562SND1
chr8124027769124027875-CDS,intron-Distal3.227744.38519K562BUD13
chr8124042844124042868-CDS,intron-Distal,intron-Proximal3.843434.38503K562SND1
chr8124033723124033792-CDS,intron-Distal,intron-Proximal5.7879010.98371K562SF3B4
chr8124053947124054027-intron-Distal4.100584.75425K562EFTUD2
chr8124043097124043183-intron-Distal3.427105.96041K562KHSRP
chr8124031354124031431-intron-Distal,intron-Proximal3.575746.00776K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DERL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DERL1 is not available on ENCORE database.

  • 58 RBPs can affect the levels of DERL1.  








The Knockdown/knockout RNA-Seq assay for DERL1 is not available on ENCORE database.





58 RBPs can affect the gene expression of DERL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DERL1ENSG00000136986.51115.46190947.151900.235902.250301.69110HepG2ACO1
DERL1ENSG00000136986.51920.786201281.385300.583905.084904.39080HepG2AKAP1
DERL1ENSG00000136986.5748.359901060.25630-0.502603.924102.99540HepG2ASCC1
DERL1ENSG00000136986.51195.08830976.499900.291302.003901.48760HepG2BOP1
DERL1ENSG00000136986.51145.58690947.976000.273101.972801.31310HepG2CALR
DERL1ENSG00000136986.51249.181701007.310800.310401.970201.31150HepG2CIRBP
DERL1ENSG00000136986.5770.09850946.98280-0.298303.136602.43780HepG2CKAP4
DERL1ENSG00000136986.5524.07200814.85840-0.636803.513302.64450HepG2CNOT7
DERL1ENSG00000136986.5669.08110896.49590-0.422102.928602.22410HepG2CPSF6
DERL1ENSG00000136986.5991.361401196.97670-0.271902.460501.84730HepG2CELF1
DERL1ENSG00000136986.5663.05320808.33700-0.285802.198301.56400HepG2DNAJC21
DERL1ENSG00000136986.5734.482401216.33320-0.727708.812307.39300HepG2EIF4G2
DERL1ENSG00000136986.51124.882701450.63830-0.366904.742603.99410HepG2ETF1
DERL1ENSG00000136986.5813.142501113.00260-0.452903.447602.44700HepG2G3BP2
DERL1ENSG00000136986.5735.721601016.29120-0.466103.139002.46230HepG2GPKOW
DERL1ENSG00000136986.5689.17640901.72900-0.387804.386603.63850HepG2HNRNPU
DERL1ENSG00000136986.5774.92630955.87600-0.302802.294501.63310HepG2IGF2BP1
DERL1ENSG00000136986.5626.748801065.77640-0.765908.146807.05190HepG2IGF2BP2
DERL1ENSG00000136986.5485.12530921.08790-0.9250022.3941020.54570HepG2ILF2
DERL1ENSG00000136986.5901.142201163.72050-0.368902.280601.70350HepG2NCBP2
DERL1ENSG00000136986.5674.61300859.93630-0.350202.095601.44050HepG2NSUN2
DERL1ENSG00000136986.51417.46840744.785300.928306.889205.44660HepG2PABPC1
DERL1ENSG00000136986.5599.30850804.27180-0.424403.981103.11350HepG2PPIL4
DERL1ENSG00000136986.5432.51160653.22610-0.594804.326403.34130HepG2PRPF8
DERL1ENSG00000136986.5769.598701293.24610-0.7488019.1422017.86650HepG2PUM1
DERL1ENSG00000136986.51609.922101292.298700.317003.076502.36870HepG2PUM2
DERL1ENSG00000136986.51300.95580818.727600.668003.767802.94970HepG2RAVER1
DERL1ENSG00000136986.51577.017101212.453600.379204.381403.76900HepG2RBM22
DERL1ENSG00000136986.51024.841101204.78560-0.233402.069201.58690HepG2NELFE
DERL1ENSG00000136986.5861.883901122.03550-0.380604.529703.76610HepG2RECQL
DERL1ENSG00000136986.5797.491501045.68790-0.390903.038602.32800HepG2RPLP0
DERL1ENSG00000136986.5490.03590646.16870-0.399002.123801.42700HepG2RRP9
DERL1ENSG00000136986.51370.501301067.737900.360001.929701.36370HepG2SF3A3
DERL1ENSG00000136986.5958.693001127.12450-0.233502.066401.54410HepG2SF3B4
DERL1ENSG00000136986.5896.383601168.13490-0.382005.193704.28170HepG2SLBP
DERL1ENSG00000136986.5719.75020936.48390-0.379804.779503.97200HepG2SMN1
DERL1ENSG00000136986.51547.322001068.155200.534603.081602.25640HepG2SNRNP70
DERL1ENSG00000136986.5957.035701188.92830-0.313003.581503.01490HepG2SSB
DERL1ENSG00000136986.5996.04770698.122600.512605.207703.93980HepG2SUPT6H
DERL1ENSG00000136986.5677.57950876.23330-0.370903.187002.65630HepG2TIAL1
DERL1ENSG00000136986.5731.37360884.02850-0.273502.378601.84780HepG2TRIM56
DERL1ENSG00000136986.51120.60360884.489300.341302.100901.54550HepG2U2AF1
DERL1ENSG00000136986.5279.94130497.99160-0.831007.208705.97590HepG2UCHL5
DERL1ENSG00000136986.51118.97080914.213100.291502.854402.24940HepG2UTP3
DERL1ENSG00000136986.5523.77330829.87490-0.664005.807904.76980HepG2XRN2
DERL1ENSG00000136986.5903.672001041.43030-0.204701.865601.39230HepG2ZNF622
DERL1ENSG00000136986.52608.326401872.044500.478405.337304.56860K562AQR
DERL1ENSG00000136986.51029.946101459.43630-0.502802.590601.56960K562CNOT7
DERL1ENSG00000136986.51963.907902641.69240-0.427705.275803.92350K562CELF1
DERL1ENSG00000136986.51123.23010893.019700.330802.359901.51880K562EFTUD2
DERL1ENSG00000136986.51459.199001054.246100.468906.688905.80670K562FXR1
DERL1ENSG00000136986.5926.248401186.33300-0.357003.158002.00980K562HNRNPA1
DERL1ENSG00000136986.51404.495301102.382000.349302.195901.37070K562HNRNPM
DERL1ENSG00000136986.51042.613301313.75440-0.333503.427702.43570K562HNRNPU
DERL1ENSG00000136986.5901.956201249.08840-0.469703.271702.12300K562IGF2BP2
DERL1ENSG00000136986.52132.913101756.068700.280402.462501.61290K562MBNL1
DERL1ENSG00000136986.51456.17030869.010400.744609.385208.00030K562PRPF8
DERL1ENSG00000136986.53213.442802344.631200.454705.830004.64920K562PUF60
DERL1ENSG00000136986.52312.224001464.864400.658408.745707.82870K562PUS1
DERL1ENSG00000136986.51599.979701281.208000.320403.736802.79670K562SF3A3
DERL1ENSG00000136986.51298.451601040.191200.319802.925202.04410K562SF3B4
DERL1ENSG00000136986.51661.523801250.562300.409804.453203.55980K562SRSF1
DERL1ENSG00000136986.51275.91930950.965200.424004.611603.54480K562SYNCRIP
DERL1ENSG00000136986.51272.03350969.705700.391402.590301.53630K562U2AF1
DERL1ENSG00000136986.51284.907101001.421300.359503.542202.63270K562U2AF2
DERL1ENSG00000136986.5682.44700890.52520-0.383902.461201.50720K562UCHL5
DERL1ENSG00000136986.51838.040001376.777900.416806.952005.87140K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DERL1 is not available on ENCORE database.





4 RBPs can affect the splicing of DERL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDERL1ENSG00000136986.5chr8-124042844124042956124034923124035019124054209124054362-0.190000.003850.06042excludedK562SF3B4
SEDERL1ENSG00000136986.5chr8-1240371741240372901240349231240350191240542091240543620.701000.001480.01695includedK562AQR
SEDERL1ENSG00000136986.5chr8-124042844124042956124037174124037290124054209124054362-0.059000.000850.01070excludedK562AQR
SEDERL1ENSG00000136986.5chr8-124031434124031545124027681124027825124054209124054542-0.135000.000010.00033excludedK562PUS1
SEDERL1ENSG00000136986.5chr8-124031434124031545124027681124027825124054209124054542-0.102000.000400.01348excludedK562AGGF1
MXEDERL1ENSG00000136986.5chr8-1240349231240350191240371741240372901240314341240315451240542091240546630.677000.006470.044531includedK562AQR
MXEDERL1ENSG00000136986.5chr8-1240349231240350191240371741240372901240336861240337391240542091240546630.076000.000010.000081includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DERL1 is not avaliable on ENCORE database.