CDKL5

General Information

Gene Name : CDKL5
Gene ID : ENSG00000008086.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CDKL5)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CDKL5	ENSG00000008086.11	7.26	6.37	6.81	ENCSR000AEF
HepG2	CDKL5	ENSG00000008086.11	2.57	4.13	3.35	ENCSR985KAT
K562	CDKL5	ENSG00000008086.11	0.03	0.03	0.03	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CDKL5 is not avaliable on ENCORE database.

Proteins bound to RNA

CDKL5 RNA is bound by 4 proteins.

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eCLIP assay for CDKL5 is not avaliable on ENCORE database.

4 proteins are bound to CDKL5 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chrX	18534068	18534156	+	intron-Distal	4.94140	7.11021	HepG2	PTBP1
chrX	18642947	18643078	+	intron-Distal	3.87976	5.57156	HepG2	QKI
chrX	18443728	18443866	+	5'-UTR,intron-Proximal	3.50620	4.11395	HepG2	NCBP2
chrX	18465238	18465309	+	intron-Distal	4.29086	4.10336	HepG2	SUGP2
chrX	18474876	18474990	+	intron-Distal	4.58201	3.74583	HepG2	PTBP1
chrX	18515926	18516002	+	intron-Distal	4.59859	3.74583	HepG2	PTBP1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 6 of 6 entries

eCLIP assay for CDKL5 is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for CDKL5 is not available on ENCORE database.
42 RBPs can affect the levels of CDKL5.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CDKL5 is not available on ENCORE database.

42 RBPs can affect the gene expression of CDKL5 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDKL5	ENSG00000008086.6	344.99850	59.10150	2.54520	35.27640	34.00970	HepG2	SRSF1
CDKL5	ENSG00000008086.6	428.37620	204.64160	1.06570	7.64830	6.61780	HepG2	GPKOW
CDKL5	ENSG00000008086.6	158.03590	61.77250	1.35510	6.49400	5.54180	HepG2	NCBP2
CDKL5	ENSG00000008086.6	148.43070	60.52540	1.29410	6.19720	5.44170	HepG2	NELFE
CDKL5	ENSG00000008086.6	172.30290	74.13050	1.21670	6.70160	5.25290	HepG2	TUFM
CDKL5	ENSG00000008086.6	142.90070	56.59140	1.33630	6.12260	5.15540	HepG2	IGF2BP2
CDKL5	ENSG00000008086.6	83.86480	196.60900	-1.22920	5.96650	5.12760	HepG2	BOP1
CDKL5	ENSG00000008086.6	135.75180	56.36900	1.26790	5.92150	5.06610	HepG2	RECQL
CDKL5	ENSG00000008086.6	204.68720	91.70890	1.15820	5.64940	4.36770	HepG2	EEF2
CDKL5	ENSG00000008086.6	153.46510	66.26740	1.21140	5.57640	4.29920	HepG2	GEMIN5
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 42 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CDKL5

General Information

Functions

Localization

Domains (AlphaFold: CDKL5)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CDKL5 is not avaliable on ENCORE database.

4 proteins are bound to CDKL5 RNA:

eCLIP assay for CDKL5 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CDKL5 is not available on ENCORE database.

42 RBPs can affect the gene expression of CDKL5 :

The Knockdown/knockout RNA-Seq assay for CDKL5 is not available on ENCORE database.

No RBPs affect the alternative splcing events of CDKL5 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for CDKL5 is not avaliable on ENCORE database.