CCDC86

General Information

Gene Name       : CCDC86
Gene ID             : ENSG00000110104.12
Essential Gene : Yes

Functions

Localization(RBPImage: CCDC86)

Domains (AlphaFold: CCDC86)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CCDC86ENSG00000110104.1215.5825.6720.62ENCSR000AEF
HepG2CCDC86ENSG00000110104.1250.8937.5844.23ENCSR985KAT
K562CCDC86ENSG00000110104.1270.6560.8865.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
CCDC86ENCAB680LVWA302-482A1Released, ENCODE3Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CCDC86K562shRNABGKLV34-9,BGKLV34-10BGKLV34-1,BGKLV34-20.0,13.8NotSatisfiedENCODE3
CCDC86K562shRNABGKLV38-29,BGKLV38-30BGKLV38-1,BGKLV38-20.0,0.0NotSatisfiedENCODE3
CCDC86HepG2shRNABGHLV33-5,BGHLV33-6BGHLV33-1,BGHLV33-20.0,0.0NotSatisfiedENCODE3
CCDC86HepG2shRNABGHLV37-17,BGHLV37-18BGHLV37-1,BGHLV37-20.0,0.0NotSatisfiedENCODE3
CCDC86K562CRISPRBGKcLV11-23,BGKcLV11-24BGKcLV11-1,BGKcLV11-20.0,0.0NotSatisfiedENCODE4
CCDC86K562CRISPRBGKcLV11-25,BGKcLV11-26BGKcLV11-1,BGKcLV11-237.3,14.1NotSatisfiedENCODE4
CCDC86K562CRISPRBGKcLV53-21,BGKcLV53-22BGKcLV53-1,BGKcLV53-267.8,63.5ExperimentedENCORE2
CCDC86K562CRISPRBGKcLV53-23,BGKcLV53-24BGKcLV53-1,BGKcLV53-20.0,0.0ExperimentedENCORE2
CCDC86HepG2CRISPRBGHcLV10-3,BGHcLV10-4BGHcLV10-1,BGHcLV10-20.0,0.0NotSatisfiedENCODE4
CCDC86HepG2CRISPRBGHcLV10-5,BGHcLV10-6BGHcLV10-1,BGHcLV10-20.0,0.0NotSatisfiedENCODE4
CCDC86HepG2CRISPRBGHcLV12-15,BGHcLV12-16BGHcLV12-1,BGHcLV12-20.0,0.0NotSatisfiedENCODE4
CCDC86HepG2CRISPRBGHcLV12-17,BGHcLV12-18BGHcLV12-1,BGHcLV12-20.0,0.0NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    CCDC86: Click to RBP Image Database
  • Nuclei
  • Nucleolus
  • Cytoplasm
  • Compartment/Organelle
  • Mitochondria












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    CCDC86Product_ID: A302-482A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: CCDC86-human    		 HepG2_Bethyl_A302-482A_1_CCDC86.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using CCDC86 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-CCDC86 antibody (lanes under 'CCDC86').
    		 K562_Bethyl_A302-492A_1_CCDC86.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using CCDC86 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-CCDC86 antibody (lanes under 'CCDC86').








    RNA Targets

    • eCLIP assay for CCDC86 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • CCDC86 RNA is bound by 10 proteins.  







    eCLIP assay for CCDC86 is not avaliable on ENCORE database.





    10 proteins are bound to CCDC86 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr116061735360617525+3'-UTR,CDS,intron-Proximal3.048754.98322HepG2AQR
    chr116061830360618363+3'-UTR4.963965.86239HepG2IGF2BP1
    chr116061549060615526+3'-UTR,CDS3.881553.01428K562UCHL5
    chr116061840160618509+3'-UTR4.9919112.56575K562UPF1
    chr116061815260618227+3'-UTR3.088483.98280K562UPF1
    chr116061809660618143+3'-UTR3.033273.29582HepG2IGF2BP1
    chr116061809560618186+3'-UTR3.308363.29111K562FAM120A
    chr116061796360618053+3'-UTR5.010248.57616HepG2UPF1
    chr116061808660618142+3'-UTR3.950033.15159HepG2LARP4
    chr116061830660618387+3'-UTR4.713726.71037HepG2UPF1
    chr116061785960617958+3'-UTR3.395704.51679HepG2UPF1
    chr116061551760615565+3'-UTR,CDS,intron-Proximal3.299316.46344HepG2PRPF8
    chr116061826460618395+3'-UTR3.006203.13612K562IGF2BP1
    chr116061791260618052+3'-UTR4.868457.01394HepG2AKAP1
    chr116061808660618142+3'-UTR5.015058.46737HepG2UPF1
    chr116061830760618401+3'-UTR5.2966214.94017K562UPF1
    chr116061819460618226+3'-UTR4.563673.39700HepG2PCBP2
    chr116061821760618295+3'-UTR3.387955.50025HepG2IGF2BP1
    chr116061815760618242+3'-UTR4.117757.35773HepG2UPF1
    chr116061808860618137+3'-UTR4.752894.22051K562UPF1
    chr116061807560618141+3'-UTR3.224943.11120HepG2AKAP1
    chr116061822760618301+3'-UTR3.332115.75802K562UPF1
    chr116061020860610330+5'-UTR,CDS4.907847.38783HepG2G3BP1
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for CCDC86 is not avaliable on ENCORE database.



    Diffrential Expression

    • The Knockdown/knockout assay for CCDC86 is not available on ENCORE database.

    • 106 RBPs can affect the levels of CCDC86.  








    The Knockdown/knockout RNA-Seq assay for CCDC86 is not available on ENCORE database.





    106 RBPs can affect the gene expression of CCDC86 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    CCDC86ENSG00000110104.7918.67720638.865400.523902.394201.46390HepG2ADAR
    CCDC86ENSG00000110104.7665.87320961.47990-0.530007.306906.12580HepG2AKAP8L
    CCDC86ENSG00000110104.7602.148301097.26590-0.8657011.387009.99380HepG2CALR
    CCDC86ENSG00000110104.71280.531101730.45300-0.434402.745501.77410HepG2CCAR1
    CCDC86ENSG00000110104.71226.28510956.773800.357904.984404.13980HepG2CKAP4
    CCDC86ENSG00000110104.7648.481401513.14700-1.2224023.2438021.49490HepG2CPSF6
    CCDC86ENSG00000110104.71449.45490982.158900.5614010.217609.13340HepG2CELF1
    CCDC86ENSG00000110104.7825.918101055.84800-0.354302.177101.50750HepG2DAZAP1
    CCDC86ENSG00000110104.71040.11250885.076300.232802.258901.50040HepG2DDX19B
    CCDC86ENSG00000110104.7296.63780630.98570-1.0889013.9824012.59980HepG2DDX21
    CCDC86ENSG00000110104.7325.25030617.41120-0.9247011.108609.32100HepG2DDX24
    CCDC86ENSG00000110104.7885.557201204.58080-0.443903.756902.58700HepG2DDX5
    CCDC86ENSG00000110104.7360.37520620.46810-0.783908.040706.45940HepG2DHX30
    CCDC86ENSG00000110104.7533.29840915.58020-0.7797013.2745012.01710HepG2DKC1
    CCDC86ENSG00000110104.7518.74390643.30520-0.310502.191801.55830HepG2DNAJC21
    CCDC86ENSG00000110104.7733.17730997.98600-0.444903.268402.38720HepG2EIF4G2
    CCDC86ENSG00000110104.7962.859401350.53740-0.488104.646303.26860HepG2ESF1
    CCDC86ENSG00000110104.7997.479401769.67770-0.8271022.3114020.88320HepG2ETF1
    CCDC86ENSG00000110104.7452.70160601.27710-0.409502.829401.67260HepG2FASTKD2
    CCDC86ENSG00000110104.7611.281901515.82410-1.310208.200306.46560HepG2FTO
    CCDC86ENSG00000110104.7796.12920591.775500.427902.966502.03620HepG2GEMIN5
    CCDC86ENSG00000110104.7802.228501715.15990-1.0963016.5730015.12990HepG2GPKOW
    CCDC86ENSG00000110104.71198.92190913.647600.391905.196403.90490HepG2HDGF
    CCDC86ENSG00000110104.7488.53450722.41440-0.564404.192903.35230HepG2HNRNPC
    CCDC86ENSG00000110104.71411.12080961.731800.5530012.5816011.23970HepG2HNRNPL
    CCDC86ENSG00000110104.7613.554301636.81860-1.4156029.1351027.44490HepG2HNRNPLL
    CCDC86ENSG00000110104.71165.31360717.638100.699309.603408.52790HepG2HNRNPU
    CCDC86ENSG00000110104.71279.375301756.40140-0.457205.972204.95010HepG2IGF2BP1
    CCDC86ENSG00000110104.7892.01270539.769300.724607.248405.46410HepG2LARP7
    CCDC86ENSG00000110104.72398.03610883.212801.4409023.1462021.46490HepG2MATR3
    CCDC86ENSG00000110104.7738.294501274.11560-0.7872011.6951010.14920HepG2MSI2
    CCDC86ENSG00000110104.7515.340601669.58290-1.6959023.5905020.96400HepG2MTPAP
    CCDC86ENSG00000110104.71324.27670726.301700.866504.086202.74030HepG2NONO
    CCDC86ENSG00000110104.7567.237101451.43270-1.3555027.3545025.39710HepG2NSUN2
    CCDC86ENSG00000110104.71293.57130896.910200.528208.636907.66270HepG2PCBP1
    CCDC86ENSG00000110104.71664.890401061.084000.649807.575506.69480HepG2PUM1
    CCDC86ENSG00000110104.7704.25270974.75790-0.469006.487205.61470HepG2PUS1
    CCDC86ENSG00000110104.7682.89350988.40620-0.533406.130605.25210HepG2QKI
    CCDC86ENSG00000110104.7532.16730897.04610-0.753309.502208.30830HepG2RBM25
    CCDC86ENSG00000110104.71120.82090650.908200.783908.040006.33980HepG2RBM27
    CCDC86ENSG00000110104.71236.21230646.841600.9343015.6505014.35340HepG2RPS19
    CCDC86ENSG00000110104.7909.36940612.789500.569403.937702.63910HepG2RPS5
    CCDC86ENSG00000110104.72732.045301382.694000.982406.679505.60280HepG2SF3A3
    CCDC86ENSG00000110104.7681.621701620.06360-1.2490025.5092023.62000HepG2SF3B1
    CCDC86ENSG00000110104.7773.74780950.17210-0.296302.660702.07870HepG2SF3B4
    CCDC86ENSG00000110104.71791.07990885.756501.015703.044501.50930HepG2SFPQ
    CCDC86ENSG00000110104.71006.88660745.283500.433906.307505.39940HepG2SMN1
    CCDC86ENSG00000110104.71154.13610625.950000.882605.208803.86850HepG2SMNDC1
    CCDC86ENSG00000110104.71183.548201670.59920-0.497209.894909.10630HepG2SRFBP1
    CCDC86ENSG00000110104.7847.29440991.77750-0.227201.764701.36310HepG2SRSF1
    CCDC86ENSG00000110104.71297.288901743.37470-0.426402.778501.77510HepG2SRSF3
    CCDC86ENSG00000110104.71406.542601752.43780-0.317204.468003.61640HepG2SRSF7
    CCDC86ENSG00000110104.7800.559701450.45870-0.8574022.5966021.43950HepG2SSB
    CCDC86ENSG00000110104.71401.420501019.187200.459403.281801.89060HepG2SSRP1
    CCDC86ENSG00000110104.7630.384901051.51210-0.738206.413304.62930HepG2STAU1
    CCDC86ENSG00000110104.71494.330301122.357100.412906.746205.85040HepG2SUCLG1
    CCDC86ENSG00000110104.7842.152101063.02640-0.336002.296401.43400HepG2SUPT6H
    CCDC86ENSG00000110104.7248.10980786.58910-1.664604.845103.98850HepG2SUPV3L1
    CCDC86ENSG00000110104.7394.90960891.45820-1.1746023.8901022.46560HepG2TAF15
    CCDC86ENSG00000110104.7745.110001595.68330-1.0986020.3222018.69260HepG2TARDBP
    CCDC86ENSG00000110104.7485.64400819.11810-0.754209.902708.34280HepG2TIA1
    CCDC86ENSG00000110104.7568.61070697.31580-0.294401.905501.47310HepG2TIAL1
    CCDC86ENSG00000110104.7906.95900703.553300.366303.816403.17620HepG2TRIM56
    CCDC86ENSG00000110104.71352.35600976.583600.469605.538004.25020HepG2TUFM
    CCDC86ENSG00000110104.7818.27620464.541900.816704.218003.27990HepG2UCHL5
    CCDC86ENSG00000110104.7751.752201226.23810-0.7059014.6858013.31910HepG2UPF1
    CCDC86ENSG00000110104.71021.507201260.40170-0.303203.147502.03840HepG2UTP18
    CCDC86ENSG00000110104.71984.032801183.884800.7448019.3580017.99290HepG2UTP3
    CCDC86ENSG00000110104.7333.659301311.94000-1.9753026.8952025.19840HepG2ZC3H8
    CCDC86ENSG00000110104.7929.94900612.167100.603102.728401.44420HepG2ZRANB2
    CCDC86ENSG00000110104.71384.989201072.121500.369303.293401.98910K562AARS
    CCDC86ENSG00000110104.7864.67670720.867900.262302.046201.54410K562AGGF1
    CCDC86ENSG00000110104.72868.137302100.683900.449203.731502.26340K562APOBEC3C
    CCDC86ENSG00000110104.71022.398001330.76910-0.380302.853501.96710K562BOP1
    CCDC86ENSG00000110104.71258.335501710.77490-0.443105.411303.27950K562CEBPZ
    CCDC86ENSG00000110104.71535.785802205.07910-0.521902.824301.74750K562CNOT7
    CCDC86ENSG00000110104.7930.702601414.94650-0.604408.277306.90840K562CPSF6
    CCDC86ENSG00000110104.71397.49790855.332500.708203.341901.87200K562DDX27
    CCDC86ENSG00000110104.74685.784002149.286701.1243049.7847047.38210K562DDX47
    CCDC86ENSG00000110104.71284.54170807.169400.670208.817407.08450K562DKC1
    CCDC86ENSG00000110104.71456.818302099.51590-0.527209.829608.59930K562EIF2S2
    CCDC86ENSG00000110104.72287.51440970.913701.2363013.5003011.31250K562EIF3A
    CCDC86ENSG00000110104.71154.68270359.957901.6815049.6417046.27920K562EIF3G
    CCDC86ENSG00000110104.7751.99830554.007100.440702.219001.48080K562EIF4A3
    CCDC86ENSG00000110104.7946.856101439.75760-0.604606.913405.53590K562FMR1
    CCDC86ENSG00000110104.7745.492501220.36040-0.711007.634306.03680K562FTO
    CCDC86ENSG00000110104.72043.46840576.136301.8264066.4392063.76750K562FXR1
    CCDC86ENSG00000110104.7964.185701350.89140-0.486504.871103.82060K562GPKOW
    CCDC86ENSG00000110104.73356.015602797.785100.262402.404201.69740K562GRSF1
    CCDC86ENSG00000110104.7718.909401173.42630-0.706809.269908.22800K562HNRNPC
    CCDC86ENSG00000110104.72304.796701766.063600.384002.829101.88800K562HNRNPM
    CCDC86ENSG00000110104.72289.050002911.32750-0.346903.212002.35870K562HSPD1
    CCDC86ENSG00000110104.71332.936702012.10240-0.594103.242501.68690K562ILF2
    CCDC86ENSG00000110104.7673.244601153.58270-0.776906.840705.30230K562KRR1
    CCDC86ENSG00000110104.71052.19910451.466101.2206019.7566017.35000K562MAGOH
    CCDC86ENSG00000110104.7830.33690450.483400.882105.635604.25810K562MATR3
    CCDC86ENSG00000110104.71077.71660891.770300.273102.192401.39910K562MBNL1
    CCDC86ENSG00000110104.71510.335401769.30880-0.228302.533701.75860K562MTPAP
    CCDC86ENSG00000110104.71511.670801965.96220-0.379108.163106.97780K562NSUN2
    CCDC86ENSG00000110104.7613.00930401.612900.610003.408402.32390K562PCBP2
    CCDC86ENSG00000110104.71328.588002363.34710-0.8309011.466309.77280K562PCBP3
    CCDC86ENSG00000110104.71214.831701812.68850-0.577408.736507.34650K562POLR2G
    CCDC86ENSG00000110104.71651.07450864.892000.9327012.7182011.09900K562PRPF8
    CCDC86ENSG00000110104.71385.62780438.660401.6593021.8732020.08000K562PTBP1
    CCDC86ENSG00000110104.73711.602002597.469600.514806.625305.36280K562PUF60
    CCDC86ENSG00000110104.7917.37700743.904200.302301.778701.32410K562PUS1
    CCDC86ENSG00000110104.7596.67090420.383000.505102.653901.83200K562RBM22
    CCDC86ENSG00000110104.7729.38100442.442000.721102.624901.56350K562NELFE
    CCDC86ENSG00000110104.71809.57270880.855701.0386014.4680012.57600K562RPS19
    CCDC86ENSG00000110104.71171.56760474.617901.303505.018203.61540K562RPS3
    CCDC86ENSG00000110104.72822.689401615.398300.805105.201103.71360K562SAFB
    CCDC86ENSG00000110104.7922.018901284.87070-0.478803.527302.42510K562SF3B1
    CCDC86ENSG00000110104.7208.69320330.52640-0.663404.048602.02610K562SND1
    CCDC86ENSG00000110104.71183.83660909.776400.379803.098401.99830K562SRFBP1
    CCDC86ENSG00000110104.7807.28740430.082800.9084010.623709.24990K562SRSF1
    CCDC86ENSG00000110104.71352.061701754.66750-0.376004.983703.39630K562SRSF7
    CCDC86ENSG00000110104.7211.36540371.30850-0.812906.731804.60960K562SSB
    CCDC86ENSG00000110104.71826.681902817.44620-0.625208.535906.03180K562SSRP1
    CCDC86ENSG00000110104.71822.213002576.99460-0.500005.008703.24470K562STAU1
    CCDC86ENSG00000110104.72924.074501818.283500.6853013.9251012.08100K562SYNCRIP
    CCDC86ENSG00000110104.7669.38890435.165600.621204.350103.45660K562TARDBP
    CCDC86ENSG00000110104.71859.272202512.28520-0.434302.916701.48480K562TRIP6
    CCDC86ENSG00000110104.7635.95110886.15350-0.478603.755602.55260K562UCHL5
    CCDC86ENSG00000110104.71676.292202084.54340-0.314502.370301.70280K562UPF1
    CCDC86ENSG00000110104.71131.823701783.69100-0.656204.788703.62140K562WDR3
    CCDC86ENSG00000110104.72736.328801854.741800.5609015.8208014.02060K562WDR43
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for CCDC86 is not available on ENCORE database.





    1 RBPs can affect the splicing of CCDC86 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    A5SSCCDC86ENSG00000110104.7chr11+6061539660615582606153966061552660617412606174870.070000.000000.00000longerK562AQR

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for CCDC86 is not avaliable on ENCORE database.