GAB2

General Information

Gene Name       : GAB2
Gene ID             : ENSG00000033327.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GAB2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GAB2ENSG00000033327.125.505.375.44ENCSR000AEF
HepG2GAB2ENSG00000033327.122.802.992.90ENCSR985KAT
K562GAB2ENSG00000033327.1218.7116.6117.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GAB2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GAB2 RNA is bound by 23 proteins.  







eCLIP assay for GAB2 is not avaliable on ENCORE database.





23 proteins are bound to GAB2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117792802077928115-3'-UTR,intron-Distal7.0812329.59196K562UPF1
chr117792905477929152-3'-UTR,intron-Distal5.3224214.14667K562UPF1
chr117792917377929246-3'-UTR,intron-Distal6.6011316.89355K562UPF1
chr117792924677929347-3'-UTR,intron-Distal7.4696134.94350K562UPF1
chr117792806177928123-3'-UTR,intron-Distal4.434245.19234K562LIN28B
chr117792724377927256-3'-UTR,intron-Distal5.194768.79592K562LIN28B
chr117792637477926392-3'-UTR,intron-Distal4.656574.85237K562UPF1
chr117792720277927243-3'-UTR,intron-Distal4.9463813.66569K562LIN28B
chr117792642577926487-3'-UTR,intron-Distal3.9495514.35038K562UPF1
chr117793002677930082-3'-UTR,intron-Distal3.224433.91588K562UPF1
chr117792892777928995-3'-UTR,intron-Distal3.199436.16228K562UPF1
chr117792642877926480-3'-UTR,intron-Distal3.264377.21373K562TIA1
chr117799188777991939-3'-UTR,5'-UTR,CDS,intron-Distal4.074493.32022K562UCHL5
chr117792718077927202-3'-UTR,intron-Distal3.356633.58206K562LIN28B
chr117792928477929339-3'-UTR,intron-Distal3.591574.50730K562AKAP8L
chr117792665877926724-3'-UTR,intron-Distal5.895599.60749K562UPF1
chr117799166177991767-CDS,intron-Distal3.079167.33292K562ZNF622
chr117793786277937967-CDS,intron-Distal,intron-Proximal5.035515.01757K562IGF2BP2
chr117793042977930498-CDS,intron-Distal3.552626.69182K562AQR
chr117793460977934673-CDS,intron-Distal3.420635.35144K562ZNF622
chr117811862978118702-intron-Distal6.4730219.26307K562PTBP1
chr117812436978124413-intron-Distal4.754324.90095K562PTBP1
chr117793613477936154-intron-Distal,intron-Proximal4.874885.69951K562AQR
chr117810939278109480-intron-Distal3.002903.03131K562HNRNPL
chr117811803078118099-intron-Distal3.254853.09339K562MATR3
chr117809572178095813-intron-Distal3.082265.68399HepG2SUGP2
chr117812420478124264-intron-Distal4.348023.79098HepG2SUGP2
chr117809499978095072-intron-Distal3.332995.59399HepG2SUGP2
chr117811864278118705-intron-Distal4.586005.26569K562MATR3
chr117811904478119102-intron-Distal3.957213.63454HepG2SUGP2
chr117811578178115843-intron-Distal3.648713.35103HepG2QKI
chr117807355678073625-intron-Distal4.532545.19823K562KHSRP
chr117812798578128080-intron-Distal3.934735.59281K562HNRNPM
chr117806731278067379-intron-Distal4.828096.12104HepG2QKI
chr117793610977936134-intron-Distal,intron-Proximal4.986076.04760K562AQR
chr117808169478081782-intron-Distal3.3043911.36753K562AGGF1
chr117812435578124435-intron-Distal4.515275.61723K562MATR3
chr117811863678118668-intron-Distal5.156146.42900HepG2PTBP1
chr117802086278020987-intron-Distal3.950915.31527K562AGGF1
chr117811248178112523-intron-Distal4.214924.27660K562HNRNPL
chr117800278378002897-intron-Distal4.9695711.33665HepG2XPO5
chr117811972078119898-intron-Distal3.118654.63615HepG2HNRNPL
chr117811901878119103-intron-Distal3.285554.03284K562MATR3
chr117811891178118998-intron-Distal4.639243.62238HepG2MATR3
chr117793438277934458-intron-Distal,intron-Proximal4.464547.15298K562AQR
chr117811830578118338-intron-Distal3.169353.69083K562PTBP1
chr117807104378071108-intron-Distal3.690896.39777K562PTBP1
chr117811252978112563-intron-Distal3.136645.47357K562HNRNPL
chr117805914578059239-intron-Distal4.169353.42734K562PTBP1
chr117812852178128618-intron-Distal3.589677.12934K562CSTF2T
chr117812850978128636-intron-Distal3.302934.88776HepG2PRPF4
chr117808168078081737-intron-Distal3.366766.43604K562HNRNPL
chr117793131777931343-intron-Distal,intron-Proximal5.728358.88118K562AQR
chr117811577578115865-intron-Distal4.591664.35360K562QKI
chr117812794378127985-intron-Distal3.329423.72827K562HNRNPM
chr117812852478128651-intron-Distal5.1040111.30153HepG2EFTUD2
chr117810936278109462-intron-Distal4.225044.45537HepG2HNRNPL
chr117812799778128048-intron-Distal4.311258.71921HepG2HNRNPM
chr117811254778112657-intron-Distal4.0372914.59443HepG2HNRNPL
chr117812461878124762-intron-Distal3.264593.99165HepG2PTBP1
chr117812461778124739-intron-Distal4.0892411.85264K562PTBP1
chr117812852078128627-intron-Distal3.236513.09778K562XRN2
chr117811866878118689-intron-Distal4.334706.24904HepG2PTBP1
chr117793135977931364-intron-Distal,intron-Proximal4.492116.48405K562AQR
chr117809590278095947-intron-Distal3.082983.10640HepG2SUGP2
chr117812461178124691-intron-Distal4.854306.75776K562MATR3
chr117808169178081743-intron-Distal3.737003.04956HepG2HNRNPL
chr117811871678118764-intron-Distal5.387056.40067K562PTBP1
chr117812805478128117-intron-Distal4.576836.16396K562NONO
chr117802098778021073-intron-Distal3.692976.14017HepG2HNRNPL
chr117811878778118803-intron-Distal4.317083.91475K562PTBP1
chr117812853378128644-intron-Distal3.115226.54781HepG2NKRF
chr117812822178128287-intron-Distal3.402803.19036K562XRN2
chr117809538178095430-intron-Distal4.379305.31529HepG2SUGP2
chr117798526177985354-intron-Distal4.246995.63677K562PTBP1
chr117809602178096089-intron-Distal3.346027.32436HepG2SUGP2
chr117812794878127997-intron-Distal4.889896.08412HepG2HNRNPM
chr117812857878128640-intron-Distal3.977543.94684HepG2CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GAB2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GAB2 is not available on ENCORE database.

  • 118 RBPs can affect the levels of GAB2.  








The Knockdown/knockout RNA-Seq assay for GAB2 is not available on ENCORE database.





118 RBPs can affect the gene expression of GAB2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GAB2ENSG00000033327.8505.68950842.78390-0.736906.096804.75840HepG2ABCF1
GAB2ENSG00000033327.8290.52490429.65940-0.564503.550302.43680HepG2ADAR
GAB2ENSG00000033327.8495.68420812.32630-0.712605.462504.74470HepG2AKAP1
GAB2ENSG00000033327.8588.15990455.897100.367402.468101.73690HepG2CALR
GAB2ENSG00000033327.8351.96960560.03310-0.670108.342807.30950HepG2CKAP4
GAB2ENSG00000033327.8467.74570941.55780-1.009302.945002.15420HepG2CNOT7
GAB2ENSG00000033327.8125.23420194.58770-0.635802.995601.87840HepG2CSTF2
GAB2ENSG00000033327.8774.23400489.354000.661808.920707.89100HepG2CELF1
GAB2ENSG00000033327.8762.39350526.152600.535007.306906.18710HepG2DAZAP1
GAB2ENSG00000033327.8378.06860518.02300-0.454404.316103.30250HepG2DDX19B
GAB2ENSG00000033327.8952.31750542.074700.812904.926003.63580HepG2DDX59
GAB2ENSG00000033327.8303.12490535.85650-0.821909.840508.72260HepG2DKC1
GAB2ENSG00000033327.8558.61440432.643700.368602.683601.98790HepG2DNAJC21
GAB2ENSG00000033327.8329.03270428.82910-0.382202.814602.15790HepG2DNAJC2
GAB2ENSG00000033327.8300.31020523.97450-0.803006.452305.10160HepG2EEF2
GAB2ENSG00000033327.8497.10870333.044700.577703.216602.01430HepG2AGO1
GAB2ENSG00000033327.8224.12950341.50800-0.607603.940802.67790HepG2EIF3G
GAB2ENSG00000033327.81125.597301547.29550-0.459103.872201.76600HepG2EIF3H
GAB2ENSG00000033327.8334.23770710.14290-1.0872011.6285010.34430HepG2EIF4A3
GAB2ENSG00000033327.8715.31240497.262700.524504.155903.16920HepG2EIF4G2
GAB2ENSG00000033327.8496.04160730.10790-0.557604.399803.05050HepG2ESF1
GAB2ENSG00000033327.8250.63500380.18130-0.601104.378302.87700HepG2FAM120A
GAB2ENSG00000033327.81221.55270851.023400.521303.911603.00880HepG2FIP1L1
GAB2ENSG00000033327.8512.87820705.61900-0.460303.025102.09300HepG2G3BP2
GAB2ENSG00000033327.8269.79140378.69400-0.489202.528501.67620HepG2GEMIN5
GAB2ENSG00000033327.8154.89670436.78860-1.4956017.0680015.68730HepG2HNRNPA1
GAB2ENSG00000033327.8722.31390576.931200.324102.538201.85040HepG2HNRNPF
GAB2ENSG00000033327.8363.28530673.02270-0.889609.111607.90180HepG2HNRNPK
GAB2ENSG00000033327.8673.70110516.393000.383502.194901.62780HepG2HNRNPLL
GAB2ENSG00000033327.8433.49370587.20810-0.437902.975901.98990HepG2HNRNPM
GAB2ENSG00000033327.8797.910801210.97910-0.601904.641103.05450HepG2HSPD1
GAB2ENSG00000033327.8738.83900568.109100.379002.758602.03580HepG2IGF2BP1
GAB2ENSG00000033327.8271.47530445.91740-0.716005.115803.45580HepG2LIN28B
GAB2ENSG00000033327.8475.98500716.74920-0.590604.351303.53160HepG2MAGOH
GAB2ENSG00000033327.8205.65540720.76160-1.8093026.2193024.45340HepG2MATR3
GAB2ENSG00000033327.8537.10890688.82380-0.358902.177701.45530HepG2MSI2
GAB2ENSG00000033327.8800.011001147.47660-0.520403.106901.59020HepG2NKRF
GAB2ENSG00000033327.8416.52350521.73310-0.324901.947201.30500HepG2NOL12
GAB2ENSG00000033327.81348.76780860.939000.647602.653101.78810HepG2PABPC1
GAB2ENSG00000033327.8472.20000706.48570-0.581306.906706.01760HepG2PCBP1
GAB2ENSG00000033327.8256.96710431.43380-0.747604.240702.97090HepG2PCBP2
GAB2ENSG00000033327.8476.90070669.30630-0.489005.150704.13010HepG2PRPF4
GAB2ENSG00000033327.8656.00690528.705600.311102.864602.26360HepG2PUM1
GAB2ENSG00000033327.8795.51870528.314800.590406.418305.41310HepG2PUM2
GAB2ENSG00000033327.8882.40840416.289101.083807.864506.71290HepG2RAVER1
GAB2ENSG00000033327.81032.40760815.967700.339303.013202.12020HepG2RBM15
GAB2ENSG00000033327.8251.71290415.77820-0.724004.810503.40290HepG2RCC2
GAB2ENSG00000033327.8485.74190800.04610-0.719909.922209.01430HepG2NELFE
GAB2ENSG00000033327.8557.86470745.16900-0.417703.871003.15840HepG2RECQL
GAB2ENSG00000033327.8967.82000621.547200.638804.433803.59910HepG2RPLP0
GAB2ENSG00000033327.8267.41260409.02230-0.613102.906101.94070HepG2RPS10
GAB2ENSG00000033327.8436.38130946.55550-1.117103.147802.29570HepG2RPS3A
GAB2ENSG00000033327.8384.54810236.301100.702403.333002.48050HepG2RRP9
GAB2ENSG00000033327.8640.39970429.807800.575206.895705.94590HepG2SAFB2
GAB2ENSG00000033327.8793.76870511.121200.635005.892404.89590HepG2SF3B1
GAB2ENSG00000033327.8583.37910748.42500-0.359402.074701.55150HepG2SF3B4
GAB2ENSG00000033327.8609.12080477.564100.350903.046302.31450HepG2SLBP
GAB2ENSG00000033327.8623.46960326.204400.934402.856801.52200HepG2SNRNP200
GAB2ENSG00000033327.81928.25860863.710001.1586045.6697044.28160HepG2SRFBP1
GAB2ENSG00000033327.8434.26200781.21060-0.8471013.2317012.36360HepG2SRSF1
GAB2ENSG00000033327.81077.47720549.984700.970106.449904.86420HepG2SRSF3
GAB2ENSG00000033327.8849.19690566.827600.583102.962102.24560HepG2SRSF7
GAB2ENSG00000033327.81080.40150635.570900.7653016.1488015.01410HepG2SRSF9
GAB2ENSG00000033327.8252.02590749.91100-1.5731038.9262037.52460HepG2SSB
GAB2ENSG00000033327.8704.62700559.255700.333302.940602.30360HepG2SUCLG1
GAB2ENSG00000033327.8591.370701184.86490-1.002605.741804.25890HepG2TBRG4
GAB2ENSG00000033327.8989.48150645.203400.616807.794106.40490HepG2TIA1
GAB2ENSG00000033327.8311.86550468.96410-0.588603.358102.81670HepG2TIAL1
GAB2ENSG00000033327.81282.78930728.030000.817106.867305.88940HepG2U2AF1
GAB2ENSG00000033327.81164.25860379.372701.617606.920805.29320HepG2U2AF2
GAB2ENSG00000033327.8378.51370637.61560-0.752307.384706.33540HepG2UPF1
GAB2ENSG00000033327.8476.28430655.35600-0.460503.661702.47360HepG2UTP18
GAB2ENSG00000033327.8194.49410303.63950-0.642602.893102.15150HepG2XRN2
GAB2ENSG00000033327.8484.79010660.52800-0.446304.659903.82540HepG2ZC3H8
GAB2ENSG00000033327.8871.71910701.250700.313802.707602.16470HepG2ZNF622
GAB2ENSG00000033327.81409.449901770.97510-0.329402.576301.40360K562ABCF1
GAB2ENSG00000033327.85445.837907433.00360-0.4488012.6561011.53760K562AGGF1
GAB2ENSG00000033327.86108.922408167.62260-0.419005.187303.74190K562AKAP8
GAB2ENSG00000033327.83354.915107734.34650-1.2050036.8927034.05090K562AKAP8L
GAB2ENSG00000033327.81436.951501815.92580-0.337702.991501.70020K562APOBEC3C
GAB2ENSG00000033327.8960.829801544.01730-0.684308.124207.20650K562AQR
GAB2ENSG00000033327.85520.577808115.13330-0.5558013.8665011.65390K562ATP5C1
GAB2ENSG00000033327.81559.411601203.037100.374202.557801.72020K562BOP1
GAB2ENSG00000033327.86180.869308882.94670-0.523208.504106.42830K562CCDC124
GAB2ENSG00000033327.81891.077301279.207900.563908.133406.77390K562CPSF6
GAB2ENSG00000033327.82029.535302530.81430-0.318503.774702.62900K562CELF1
GAB2ENSG00000033327.86608.235208720.94550-0.400203.880002.13450K562DDX19B
GAB2ENSG00000033327.81986.241101253.820500.6636011.035608.79300K562DDX3X
GAB2ENSG00000033327.82555.665702072.287000.302401.903101.34400K562DDX47
GAB2ENSG00000033327.87301.102608322.90320-0.189002.234901.45870K562DKC1
GAB2ENSG00000033327.83276.212701168.087101.4878073.5997071.09130K562EIF2S2
GAB2ENSG00000033327.81761.96200933.744100.916007.554405.84980K562EIF3A
GAB2ENSG00000033327.81676.118902058.03480-0.296103.918902.80290K562EIF4G2
GAB2ENSG00000033327.81028.999801273.06410-0.307102.182701.42750K562FIP1L1
GAB2ENSG00000033327.82112.970101301.497300.699006.181104.88820K562FMR1
GAB2ENSG00000033327.81424.337501103.107500.368602.631001.74160K562FTO
GAB2ENSG00000033327.81548.275201235.843700.325103.484401.45910K562FUBP3
GAB2ENSG00000033327.81010.443401362.32170-0.431105.509604.69620K562FXR1
GAB2ENSG00000033327.81639.792301236.056500.407704.087702.31120K562G3BP1
GAB2ENSG00000033327.8715.938001001.01860-0.483602.980802.24320K562G3BP2
GAB2ENSG00000033327.81542.969901221.356200.337102.785201.98830K562GPKOW
GAB2ENSG00000033327.81105.133601556.43060-0.494004.612603.63750K562GRSF1
GAB2ENSG00000033327.81331.727301872.90000-0.492006.057204.43230K562HNRNPL
GAB2ENSG00000033327.81759.632001047.127900.748708.657906.84570K562HNRNPM
GAB2ENSG00000033327.86029.960801725.984401.8046068.2317065.28100K562HSPD1
GAB2ENSG00000033327.84626.097908208.18220-0.8273011.080509.09270K562KIF1C
GAB2ENSG00000033327.81589.408201048.910300.599507.602105.16660K562LARP7
GAB2ENSG00000033327.81014.269001355.86520-0.418803.571102.50950K562MATR3
GAB2ENSG00000033327.87310.637309195.22240-0.330904.401403.20490K562MBNL1
GAB2ENSG00000033327.81560.140602193.61050-0.491605.783704.15760K562MSI2
GAB2ENSG00000033327.83329.759706445.17550-0.9528013.1066010.68480K562NAA15
GAB2ENSG00000033327.81666.582001308.032700.349403.706502.26150K562NCBP2
GAB2ENSG00000033327.81947.999201730.479700.170702.126501.46350K562NSUN2
GAB2ENSG00000033327.81750.591201328.447000.398003.676902.11380K562PCBP1
GAB2ENSG00000033327.8764.115401208.80650-0.661707.942606.25570K562PCBP2
GAB2ENSG00000033327.81393.911402011.21650-0.528904.993503.87700K562PCBP3
GAB2ENSG00000033327.82845.141602114.711400.427902.943101.45940K562PNPT1
GAB2ENSG00000033327.8953.970701542.62970-0.6934011.391809.82150K562POLR2G
GAB2ENSG00000033327.81628.855301320.128800.303102.717702.05880K562PTBP1
GAB2ENSG00000033327.81810.325902245.43100-0.310702.619301.82600K562PUF60
GAB2ENSG00000033327.83621.724407670.56960-1.0827026.4101024.72900K562PUS1
GAB2ENSG00000033327.82959.016007473.63200-1.3367069.0330065.95910K562RBM15
GAB2ENSG00000033327.81959.944601476.296600.408704.284302.27990K562RBM17
GAB2ENSG00000033327.8915.850001265.49520-0.466504.446603.34970K562RBM22
GAB2ENSG00000033327.81048.436201331.81330-0.345202.501701.46900K562NELFE
GAB2ENSG00000033327.81320.809701015.683300.378903.251501.39800K562RECQL
GAB2ENSG00000033327.81880.252103061.74640-0.703402.191801.31050K562RPS3
GAB2ENSG00000033327.82117.659201707.562300.310404.000303.02810K562SF3A3
GAB2ENSG00000033327.81560.494101161.453100.426003.043602.02290K562SF3B1
GAB2ENSG00000033327.81153.81990840.196900.457504.203702.86370K562SRFBP1
GAB2ENSG00000033327.81298.212001749.43620-0.430408.098806.59650K562SRPK2
GAB2ENSG00000033327.81051.544501294.23840-0.299602.455901.78300K562SRSF1
GAB2ENSG00000033327.81789.733601222.489100.549806.328804.63140K562SRSF5
GAB2ENSG00000033327.81707.84990916.397700.898003.159201.77140K562SSB
GAB2ENSG00000033327.81729.393501263.392900.452902.258901.52650K562TIA1
GAB2ENSG00000033327.81536.182801240.131700.308802.277001.30790K562TRA2A
GAB2ENSG00000033327.81298.59600992.637800.387503.374402.31000K562TRIM56
GAB2ENSG00000033327.82817.815401834.865400.6188017.6129015.97310K562UPF1
GAB2ENSG00000033327.85020.844707776.93550-0.631303.352301.88250K562UTP18
GAB2ENSG00000033327.82299.398401570.034600.550404.571003.43210K562WDR3
GAB2ENSG00000033327.81963.440801632.666000.266103.748802.77370K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GAB2 is not available on ENCORE database.





1 RBPs can affect the splicing of GAB2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSGAB2ENSG00000033327.8chr11-7793315077933301779331507793324177934457779347220.098000.000020.00024longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GAB2 is not avaliable on ENCORE database.