ZFP36L1

General Information

Gene Name : ZFP36L1
Gene ID : ENSG00000185650.9
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ZFP36L1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ZFP36L1	ENSG00000185650.9	43.73	53.59	48.66	ENCSR000AEF
HepG2	ZFP36L1	ENSG00000185650.9	33.91	19.26	26.59	ENCSR985KAT
K562	ZFP36L1	ENSG00000185650.9	11.22	9.22	10.22	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	ZFP36L1-BGRSLV03-RS293		ZFP36L1	Ribo-STAMP-293T	Released			shRNA	KD% = ,
RNA Bind-n-Seq	RBNS: ZFP36L1	ENCSR570AIV	ZFP36L1	cell-free sample	Released		ENCSR251CSO

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
ZFP36L1	Ribo-STAMP-293T	shRNA	ZFP36L1-BGRSLV03-51,ZFP36L1-BGRSLV03-52	NT-BGRSLV03-1,NT-BGRSLV03-2	,	Released	ENCORE2
ZFP36L1	Ribo-STAMP-293T	shRNA	BGRSLV04-67,BGRSLV04-68	BGRSLV04-1,BGRSLV04-2		NotSatisfied	ENCORE2
ZFP36L1	Ribo-STAMP-293T	shRNA	BGRSDLV02-57,BGRSDLV02-58	BGRSDLV02-1,BGRSDLV02-2		NotSatisfied	ENCORE2
ZFP36L1	Ribo-STAMP-293T	shRNA	BGRSDLV02-59dox,BGRSDLV02-60dox	BGRSDLV02-1,BGRSDLV02-2		NotSatisfied	ENCORE2
ZFP36L1	Ribo-STAMP-293T	shRNA	BGRSDLV04-45,BGRSDLV04-46	BGRSDLV04-1,BGRSDLV04-2		NotSatisfied	ENCORE2
ZFP36L1	Ribo-STAMP-293T	shRNA	BGRSDLV04-47dox,BGRSDLV04-48dox	BGRSDLV04-1,BGRSDLV04-2		NotSatisfied	ENCORE2

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
ZFP36L1	ZFP36L1	TIS11B	Released	ENCODE4

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ZFP36L1 is not avaliable on ENCORE database.

The binding motifs of ZFP36L1

Proteins bound to RNA

ZFP36L1 RNA is bound by 27 proteins.

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eCLIP assay for ZFP36L1 is not avaliable on ENCORE database.

27 proteins are bound to ZFP36L1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr14	69256132	69256175	-	3'-UTR,intron-Distal,intron-Proximal	6.57816	400.00000	HepG2	PCBP2
chr14	69256175	69256229	-	3'-UTR,intron-Distal,intron-Proximal	5.53660	83.64674	HepG2	PCBP2
chr14	69256066	69256106	-	3'-UTR,intron-Distal	5.36535	43.55845	HepG2	PCBP2
chr14	69255671	69255720	-	3'-UTR,intron-Distal	5.86924	37.10408	HepG2	PCBP2
chr14	69256469	69256482	-	3'-UTR,CDS,intron-Distal	6.16628	18.02767	K562	RBM15
chr14	69256060	69256192	-	3'-UTR,intron-Distal,intron-Proximal	3.45998	17.81121	HepG2	DDX59
chr14	69256482	69256515	-	3'-UTR,CDS,intron-Distal	5.93656	16.57154	K562	RBM15
chr14	69256109	69256132	-	3'-UTR,intron-Distal	5.41375	16.31311	HepG2	PCBP2
chr14	69255254	69255320	-	3'-UTR,intron-Distal,intron-Proximal	4.43283	16.20576	K562	PABPC4
chr14	69254463	69254511	-	3'-UTR,intron-Distal	5.06188	16.08546	K562	PUM2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 66 entries

eCLIP assay for ZFP36L1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ZFP36L1 is not available on ENCORE database.
139 RBPs can affect the levels of ZFP36L1.

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The Knockdown/knockout RNA-Seq assay for ZFP36L1 is not available on ENCORE database.

139 RBPs can affect the gene expression of ZFP36L1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ZFP36L1	ENSG00000185650.8	7494.53120	1911.29720	1.97120	99.18550	96.92490	HepG2	ACO1
ZFP36L1	ENSG00000185650.8	9452.76070	2331.78020	2.01920	63.34610	61.76690	HepG2	SRFBP1
ZFP36L1	ENSG00000185650.8	4922.25390	1143.03340	2.10640	60.12850	57.85230	HepG2	DDX6
ZFP36L1	ENSG00000185650.8	7023.26670	2064.49970	1.76630	55.36660	53.62970	HepG2	RBM22
ZFP36L1	ENSG00000185650.8	2993.69410	1589.29090	0.91340	46.91510	44.86730	HepG2	SMN1
ZFP36L1	ENSG00000185650.8	3010.38090	1500.34160	1.00460	42.94710	41.06730	HepG2	TRIM56
ZFP36L1	ENSG00000185650.8	3790.15400	1196.48950	1.66330	38.78490	36.44300	HepG2	DDX55
ZFP36L1	ENSG00000185650.8	8819.90120	4277.33270	1.04400	38.81780	36.35830	HepG2	RBM15
ZFP36L1	ENSG00000185650.8	4372.19210	1388.73870	1.65450	37.82490	36.17140	HepG2	AKAP1
ZFP36L1	ENSG00000185650.8	9060.09860	3579.10530	1.33980	38.37790	35.98620	HepG2	U2AF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 169 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ZFP36L1 is not available on ENCORE database.

1 RBPs can affect the splicing of ZFP36L1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP	Bound by RBP
SE	ZFP36L1	ENSG00000185650.8	chr14	-	69259598	69259787			69256905	69257209	69262791	69262931	0.06300	0.00012	0.03186	included	HepG2	DDX55

Showing 1 to 1 of 1 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ZFP36L1

General Information

Functions

Localization

Domains (AlphaFold: ZFP36L1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ZFP36L1 is not avaliable on ENCORE database.

27 proteins are bound to ZFP36L1 RNA:

eCLIP assay for ZFP36L1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ZFP36L1 is not available on ENCORE database.

139 RBPs can affect the gene expression of ZFP36L1 :

The Knockdown/knockout RNA-Seq assay for ZFP36L1 is not available on ENCORE database.

1 RBPs can affect the splicing of ZFP36L1 :

The Knockdown/knockout RNA-Seq assay for ZFP36L1 is not avaliable on ENCORE database.