YARS

General Information

Gene Name : YARS
Gene ID : ENSG00000134684.10
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: YARS)

Not Available

Antibody Validation

Bethyl Labs: A305-064A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	YARS	ENSG00000134684.10	139.07	122.09	130.58	ENCSR000AEF
HepG2	YARS	ENSG00000134684.10	68.11	77.94	73.03	ENCSR985KAT
K562	YARS	ENSG00000134684.10	225.23	222.25	223.74	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
YARS		A305-064A	1				BGHcLV45-81, Submitted, ENCORE2	BGKcLV44-85, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
YARS	K562	CRISPR	BGKcLV37-61,BGKcLV37-62	BGKcLV37-1,BGKcLV37-2	no change/too many bands,	NotSatisfied	ENCORE2
YARS	K562	CRISPR	YARS-BGKcLV44-85,YARS-BGKcLV44-86	NT-BGKcLV44-1,NT-BGKcLV44-2	63.4,60.5	Submitting	ENCORE2
YARS	K562	CRISPR	BGKcLV44-87,BGKcLV44-88	BGKcLV44-1,BGKcLV44-2	58.6,53.6	NotSatisfied	ENCORE2
YARS	HepG2	CRISPR	BGHcLV36-59,BGHcLV36-60	BGHcLV36-1,BGHcLV36-2	0.0,0.0	NotSatisfied	ENCORE2
YARS	HepG2	CRISPR	YARS-BGHcLV45-81,YARS-BGHcLV45-82	NT-BGHcLV45-1,NT-BGHcLV45-2	65.5,63.7	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
YARS	Product_ID: A305-064A Lot_ID: 1 Source: Bethyl Labs Target Name: YARS-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for YARS is not avaliable on ENCORE database.

Proteins bound to RNA

YARS RNA is bound by 44 proteins.

CanvasJS.com

eCLIP assay for YARS is not avaliable on ENCORE database.

44 proteins are bound to YARS RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	33252465	33252527	-	intron-Distal,intron-Proximal	4.97198	47.94619	K562	TIA1
chr1	33246762	33246827	-	intron-Distal,intron-Proximal	5.76371	36.15400	K562	SF3B4
chr1	33244994	33245114	-	CDS,intron-Distal	3.78776	21.76060	K562	RPS3
chr1	33245741	33245804	-	CDS,intron-Distal	4.47056	21.47848	K562	RPS3
chr1	33241178	33241238	-	3'-UTR,intron-Distal,intron-Proximal	3.19261	20.51086	K562	UPF1
chr1	33241013	33241105	-	3'-UTR,intron-Distal	3.48703	20.18162	K562	UPF1
chr1	33240977	33241013	-	3'-UTR,intron-Distal	4.17646	18.73632	K562	UPF1
chr1	33258710	33258812	-	intron-Distal	4.63472	18.67461	K562	PTBP1
chr1	33241443	33241505	-	3'-UTR,intron-Distal,intron-Proximal	4.11004	17.99896	K562	IGF2BP2
chr1	33241499	33241579	-	3'-UTR,intron-Distal,intron-Proximal	3.11514	17.80244	K562	RPS3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 123 entries

eCLIP assay for YARS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for YARS is not available on ENCORE database.
142 RBPs can affect the levels of YARS.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

142 RBPs can affect the gene expression of YARS :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
YARS	ENSG00000134684.6	3626.31680	1886.64140	0.94260	51.81900	49.91730	HepG2	PUM1
YARS	ENSG00000134684.6	7916.72870	14370.04730	-0.86010	39.80090	36.80030	K562	EIF4G2
YARS	ENSG00000134684.6	2527.14860	1415.66920	0.83590	36.10630	34.71050	HepG2	ZNF622
YARS	ENSG00000134684.6	22309.96470	10055.29660	1.14960	33.40750	31.03490	K562	HSPD1
YARS	ENSG00000134684.6	3515.27570	1427.61030	1.29990	29.38020	26.35870	HepG2	EIF2S2
YARS	ENSG00000134684.6	6310.55510	10676.45720	-0.75860	29.57300	26.34440	K562	CPEB4
YARS	ENSG00000134684.6	7045.89370	4328.17190	0.70290	26.83900	25.29510	HepG2	ETF1
YARS	ENSG00000134684.6	10241.07150	17671.51600	-0.78710	26.80150	24.26570	K562	CELF1
YARS	ENSG00000134684.6	13949.68930	8700.31390	0.68100	24.49120	22.70370	K562	EIF2S2
YARS	ENSG00000134684.6	10346.01590	16339.59960	-0.65930	24.45360	21.83200	K562	PUM2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 178 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

13 RBPs can affect the splicing of YARS :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239	33256762	33256855	33263363	33263444	0.13400	0.00001	included	HepG2	HNRNPK
SE	YARS	ENSG00000134684.6	chr1	-	33252540	33252704	33251970	33252048	33256762	33256855	-0.07200	0.00000	excluded	K562	AQR
SE	YARS	ENSG00000134684.6	chr1	-	33272082	33272238	33263363	33263444	33276191	33276367	-0.05200	0.00000	excluded	K562	AQR
SE	YARS	ENSG00000134684.6	chr1	-	33276191	33276367	33272082	33272212	33282788	33282918	-0.10100	0.00011	excluded	K562	SUPV3L1
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239	33252540	33252676	33263363	33263444	-0.56600	0.00007	excluded	K562	PUS1
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239	33256762	33256855	33263363	33263444	0.18600	0.00000	included	HepG2	HNRNPL
SE	YARS	ENSG00000134684.6	chr1	-	33263192	33263239	33252540	33252676	33263363	33263444	-0.56300	0.00017	excluded	K562	AGGF1
SE	YARS	ENSG00000134684.6	chr1	-	33276191	33276367	33272082	33272212	33282788	33282918	-0.11300	0.00000	excluded	K562	HNRNPC
A3SS	YARS	ENSG00000134684.6	chr1	-	33246648	33246823	33246648	33246746	33248004	33248159	0.05300	0.00000	longer	K562	AQR
A3SS	YARS	ENSG00000134684.6	chr1	-	33251970	33252133	33251970	33252048	33252540	33252704	0.05400	0.00000	longer	K562	AQR

Showing 1 to 10 of 21 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

YARS

General Information

Functions

Localization

Domains (AlphaFold: YARS)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for YARS is not avaliable on ENCORE database.

44 proteins are bound to YARS RNA:

eCLIP assay for YARS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

142 RBPs can affect the gene expression of YARS :

The Knockdown/knockout RNA-Seq assay for YARS is not available on ENCORE database.

13 RBPs can affect the splicing of YARS :

The Knockdown/knockout RNA-Seq assay for YARS is not avaliable on ENCORE database.