CIZ1

General Information

Gene Name : CIZ1
Gene ID : ENSG00000148337.20
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CIZ1)

Not Available

Antibody Validation

Thermo Fisher: PA5-27625

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CIZ1	ENSG00000148337.20	27.17	39.94	33.55	ENCSR000AEF
HepG2	CIZ1	ENSG00000148337.20	50.32	35.59	42.95	ENCSR985KAT
K562	CIZ1	ENSG00000148337.20	176.55	195.69	186.12	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CIZ1-BGKcLV19-K562	ENCSR765HSN	CIZ1	K562	Released		ENCSR978MMZ	CRISPR	KD% = 69.0,71.8
knockdown followed by RNA-seq	CIZ1-BGHcLV20-HepG2	ENCSR749QMU	CIZ1	HepG2	Released		ENCSR306EWE	CRISPR	KD% = 74.5,81.3

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CIZ1	ENCAB411FAE	PA5-27625	UF2796672B			Released, ENCODE4	BGHcLV20-3, Released, ENCODE4	BGKcLV19-9, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
CIZ1	K562	CRISPR	ENCSR765HSN	ENCSR978MMZ	CIZ1-BGKcLV19-9,CIZ1-BGKcLV19-10	NT-BGKcLV19-1,NT-BGKcLV19-2	69.0,71.8	Released	ENCODE4
CIZ1	HepG2	CRISPR	ENCSR749QMU	ENCSR306EWE	CIZ1-BGHcLV20-3,CIZ1-BGHcLV20-4	NT-BGHcLV20-1,NT-BGHcLV20-2	74.5,81.3	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CIZ1	Product_ID: PA5-27625 Lot_ID: UF2796672B Source: Thermo Fisher Target Name: CIZ1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CIZ1 is not avaliable on ENCORE database.

Proteins bound to RNA

CIZ1 RNA is bound by 41 proteins.

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eCLIP assay for CIZ1 is not avaliable on ENCORE database.

41 proteins are bound to CIZ1 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	130947861	130947973	-	CDS,intron-Distal,intron-Proximal	4.44097	46.45089	K562	PCBP1
chr9	130932259	130932298	-	intron-Distal,intron-Proximal	5.12322	42.78755	K562	AQR
chr9	130932256	130932259	-	intron-Distal,intron-Proximal	6.75624	40.23129	K562	AQR
chr9	130931381	130931463	-	CDS,intron-Distal,intron-Proximal	3.98471	38.25671	K562	UCHL5
chr9	130929381	130929433	-	CDS,intron-Distal	3.04553	37.03845	K562	ZNF622
chr9	130940652	130940735	-	CDS,intron-Distal	3.41453	36.46161	K562	ZNF622
chr9	130947892	130947967	-	CDS,intron-Distal,intron-Proximal	3.89289	36.42819	K562	IGF2BP2
chr9	130931384	130931445	-	CDS,intron-Distal,intron-Proximal	3.39764	34.34309	K562	ZNF622
chr9	130931329	130931358	-	CDS,intron-Distal,intron-Proximal	4.39566	34.27335	K562	UCHL5
chr9	130931357	130931384	-	CDS,intron-Distal,intron-Proximal	4.09330	33.35915	K562	ZNF622
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 176 entries

eCLIP assay for CIZ1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CIZ1 is not available on ENCORE database.
93 RBPs can affect the levels of CIZ1.

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The Knockdown/knockout RNA-Seq assay for CIZ1 is not available on ENCORE database.

93 RBPs can affect the gene expression of CIZ1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CIZ1	ENSG00000148337.15	25053.53620	12875.64040	0.96030	57.13130	54.55470	K562	DDX47
CIZ1	ENSG00000148337.15	5268.21830	2383.14240	1.14430	48.39020	45.14160	K562	EIF3G
CIZ1	ENSG00000148337.15	1229.23270	2039.41960	-0.73040	22.08950	21.02720	HepG2	SRFBP1
CIZ1	ENSG00000148337.15	15629.37610	10856.35350	0.52560	19.59570	18.20280	K562	AGGF1
CIZ1	ENSG00000148337.15	16123.85330	5760.42150	1.48490	18.14930	15.71230	K562	EIF3A
CIZ1	ENSG00000148337.15	11630.26400	8102.40580	0.52140	12.63350	10.76500	K562	HNRNPU
CIZ1	ENSG00000148337.15	573.39380	1890.82370	-1.72140	11.22760	10.22540	HepG2	AKAP1
CIZ1	ENSG00000148337.15	1190.65630	1805.66800	-0.60080	10.72710	9.85290	HepG2	RBM22
CIZ1	ENSG00000148337.15	9123.39510	4665.12350	0.96760	11.09880	9.42890	K562	RPS19
CIZ1	ENSG00000148337.15	5439.65100	3602.02710	0.59460	10.21750	8.87330	K562	SRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 104 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CIZ1 is not available on ENCORE database.

53 RBPs can affect the splicing of CIZ1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	CIZ1	ENSG00000148337.15	chr9	-	130940647	130940769	130939844	130940042	130940987	130941694	-0.05400	0.00000	excluded	K562	PRPF8
SE	CIZ1	ENSG00000148337.15	chr9	-	130952607	130952723	130947825	130948055	130952966	130953141	-0.23100	0.00000	excluded	HepG2	U2AF1
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952723	-0.10200	0.00001	excluded	K562	AKAP8L
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952707	-0.29500	0.00000	excluded	HepG2	U2AF2
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952723	0.15600	0.00029	included	HepG2	SFPQ
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952677	0.11500	0.00068	included	HepG2	FTO
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952723	0.38300	0.00000	included	HepG2	PCBP2
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952635	0.17700	0.00004	included	HepG2	LARP4
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952677	0.20300	0.00000	included	HepG2	RBM15
SE	CIZ1	ENSG00000148337.15	chr9	-	130950141	130950213	130947825	130948055	130952607	130952723	0.28900	0.00006	included	HepG2	TIAL1

Showing 1 to 10 of 150 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CIZ1

General Information

Functions

Localization

Domains (AlphaFold: CIZ1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CIZ1 is not avaliable on ENCORE database.

41 proteins are bound to CIZ1 RNA:

eCLIP assay for CIZ1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CIZ1 is not available on ENCORE database.

93 RBPs can affect the gene expression of CIZ1 :

The Knockdown/knockout RNA-Seq assay for CIZ1 is not available on ENCORE database.

53 RBPs can affect the splicing of CIZ1 :

The Knockdown/knockout RNA-Seq assay for CIZ1 is not avaliable on ENCORE database.