SPATS2

General Information

Gene Name : SPATS2
Gene ID : ENSG00000123352.17
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SPATS2)

Not Available

Antibody Validation

Bethyl Labs: A304-970A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SPATS2	ENSG00000123352.17	25.12	24.47	24.80	ENCSR000AEF
HepG2	SPATS2	ENSG00000123352.17	19.42	26.84	23.13	ENCSR985KAT
K562	SPATS2	ENSG00000123352.17	16.36	16.99	16.67	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SPATS2-BGKcLV33-K562		SPATS2	K562	Released			CRISPR	KD% = no band on the position,
knockdown followed by RNA-seq	SPATS2-BGKcLV33-K562	ENCSR535TPQ	SPATS2	K562	Released		ENCSR271ZAB	CRISPR	KD% = 53.3,50.8

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SPATS2	ENCAB243SMV	A304-970A	1					BGKcLV33-69, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
SPATS2	K562	CRISPR			BGKcLV33-65,BGKcLV33-66	BGKcLV33-1,BGKcLV33-2	no band on the position,	Released	ENCODE4
SPATS2	K562	CRISPR	ENCSR535TPQ	ENCSR271ZAB	SPATS2-BGKcLV33-69,SPATS2-BGKcLV33-70	NT-BGKcLV33-1,NT-BGKcLV33-2	53.3,50.8	Released	ENCODE4
SPATS2	HepG2	CRISPR			BGHcLV31-65,BGHcLV31-66	BGHcLV31-1,BGHcLV31-2	0.0,0.0	NotSatisfied	ENCODE4
SPATS2	HepG2	CRISPR			BGHcLV34-57,BGHcLV34-58	BGHcLV34-1,BGHcLV34-2	NO CLEAR BAND ON THE POSITION,	NotSatisfied	ENCORE2
SPATS2	HepG2	CRISPR			BGHcLV47-71,BGHcLV47-72	BGHcLV47-1,BGHcLV47-2	0.0,0.0	NotSatisfied	ENCORE2
SPATS2	HepG2	CRISPR			BGHcLV47-73,BGHcLV47-74	BGHcLV47-1,BGHcLV47-2	0.0,0.0	NotSatisfied	ENCORE2
SPATS2	HepG2	CRISPR			BGHcLV49-107,BGHcLV49-108	BGHcLV49-1,BGHcLV49-2	0.0,0.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SPATS2	Product_ID: A304-970A Lot_ID: 1 Source: Bethyl Labs Target Name: SPATS2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Proteins bound to RNA

SPATS2 RNA is bound by 23 proteins.

CanvasJS.com

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

23 proteins are bound to SPATS2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	49776338	49776449	+	intron-Distal	4.52405	21.16194	HepG2	QKI
chr12	49761466	49761531	+	intron-Distal,intron-Proximal	4.48806	13.83304	HepG2	FAM120A
chr12	49878378	49878450	+	CDS	3.81005	11.95754	HepG2	BCLAF1
chr12	49878370	49878453	+	CDS,intron-Proximal	3.70117	9.56042	K562	ZNF622
chr12	49883277	49883335	+	3'-UTR,CDS	4.56241	8.85766	HepG2	BCLAF1
chr12	49761464	49761598	+	intron-Distal,intron-Proximal	5.02335	7.68230	K562	CSTF2T
chr12	49790207	49790272	+	intron-Distal	4.91066	7.65425	HepG2	SUGP2
chr12	49901565	49901673	+	intron-Distal	3.89318	7.22994	K562	KHSRP
chr12	49761531	49761583	+	intron-Distal	3.67385	6.87013	HepG2	FAM120A
chr12	49883271	49883358	+	3'-UTR,CDS,intron-Proximal	4.18948	6.81381	K562	DDX24
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 59 entries

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SPATS2 is not available on ENCORE database.
66 RBPs can affect the levels of SPATS2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

66 RBPs can affect the gene expression of SPATS2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SPATS2	ENSG00000123352.13	630.74850	1004.49960	-0.67130	11.15760	10.01390	HepG2	SRSF5
SPATS2	ENSG00000123352.13	1051.76540	712.10010	0.56260	8.22080	7.50480	HepG2	SRSF1
SPATS2	ENSG00000123352.13	427.32330	684.35800	-0.67940	8.81910	7.44750	HepG2	PARN
SPATS2	ENSG00000123352.13	440.05600	751.58710	-0.77230	7.31630	6.30160	HepG2	U2AF1
SPATS2	ENSG00000123352.13	651.61720	387.11570	0.75120	7.54930	6.28950	HepG2	FUBP3
SPATS2	ENSG00000123352.13	927.36270	643.98580	0.52600	7.13470	6.23450	HepG2	PCBP1
SPATS2	ENSG00000123352.13	1025.09710	607.64370	0.75440	6.54190	5.38870	HepG2	CIRBP
SPATS2	ENSG00000123352.13	569.54080	812.13950	-0.51190	6.01090	5.04800	HepG2	SRSF7
SPATS2	ENSG00000123352.13	1651.07820	1147.22180	0.52520	6.41680	4.92240	K562	MBNL1
SPATS2	ENSG00000123352.13	669.70160	993.92040	-0.56960	6.16620	4.78840	HepG2	TUFM
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 72 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

12 RBPs can affect the splicing of SPATS2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.54700	0.00000	0.00057	included	HepG2	PTBP1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49855012	-0.37000	0.00001	0.00016	excluded	K562	AQR
SE	SPATS2	ENSG00000123352.13	chr12	+	49912855	49912965			49908337	49908396	49916533	49916636	-0.12500	0.00007	0.00120	excluded	K562	AQR
SE	SPATS2	ENSG00000123352.13	chr12	+	49848007	49848168			49761278	49761370	49854552	49854820	0.38700	0.00011	0.01218	included	K562	HNRNPL
SE	SPATS2	ENSG00000123352.13	chr12	+	49877518	49877634			49854552	49854820	49878372	49878452	0.05800	0.00012	0.00333	included	HepG2	U2AF1
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	-0.43100	0.00012	0.01238	excluded	HepG2	NCBP2
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.27900	0.00035	0.06755	included	K562	APOBEC3C
MXE	SPATS2	ENSG00000123352.13	chr12	+	49890593	49890792	49893852	49893988	49888523	49888785	49908337	49908396	0.08600	0.00035	0.00363	1included	K562	AQR
SE	SPATS2	ENSG00000123352.13	chr12	+	49765010	49765073			49761302	49761370	49854552	49854820	0.49300	0.00045	0.04207	included	HepG2	QKI
SE	SPATS2	ENSG00000123352.13	chr12	+	49906644	49906688			49893852	49893988	49908337	49908396	0.33600	0.00083	0.01210	included	HepG2	U2AF2

Showing 1 to 10 of 15 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SPATS2

General Information

Functions

Localization

Domains (AlphaFold: SPATS2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

23 proteins are bound to SPATS2 RNA:

eCLIP assay for SPATS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

66 RBPs can affect the gene expression of SPATS2 :

The Knockdown/knockout RNA-Seq assay for SPATS2 is not available on ENCORE database.

12 RBPs can affect the splicing of SPATS2 :

The Knockdown/knockout RNA-Seq assay for SPATS2 is not avaliable on ENCORE database.