PRPF18

General Information

Gene Name : PRPF18
Gene ID : ENSG00000165630.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PRPF18)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PRPF18	ENSG00000165630.13	27.14	24.07	25.61	ENCSR000AEF
HepG2	PRPF18	ENSG00000165630.13	7.88	12.70	10.29	ENCSR985KAT
K562	PRPF18	ENSG00000165630.13	14.80	17.43	16.12	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PRPF18 is not avaliable on ENCORE database.

Proteins bound to RNA

PRPF18 RNA is bound by 6 proteins.

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eCLIP assay for PRPF18 is not avaliable on ENCORE database.

6 proteins are bound to PRPF18 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr10	13644197	13644372	+	intron-Distal	3.80335	6.89441	K562	KHSRP
chr10	13658397	13658468	+	CDS,intron-Proximal	4.99859	6.58593	HepG2	BCLAF1
chr10	13658397	13658543	+	CDS,intron-Proximal	3.40533	5.10069	HepG2	GRWD1
chr10	13658402	13658503	+	CDS	3.20723	4.77136	HepG2	PPIG
chr10	13670877	13670970	+	intron-Distal	4.51186	4.66899	HepG2	HNRNPM
chr10	13658491	13658556	+	CDS,intron-Proximal	3.15634	4.34695	HepG2	BCLAF1
chr10	13658527	13658596	+	CDS,intron-Proximal	4.23026	3.86479	HepG2	PRPF8
chr10	13652062	13652184	+	CDS	3.84878	3.79347	HepG2	GRWD1
chr10	13653614	13653685	+	3'-UTR,CDS,intron-Proximal	4.54537	3.79199	HepG2	PPIG
chr10	13656017	13656087	+	CDS,intron-Proximal	4.48033	3.71570	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 10 entries

eCLIP assay for PRPF18 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PRPF18 is not available on ENCORE database.
31 RBPs can affect the levels of PRPF18.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PRPF18 is not available on ENCORE database.

31 RBPs can affect the gene expression of PRPF18 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PRPF18	ENSG00000165630.9	123.16030	264.80120	-1.10440	6.46950	5.55550	HepG2	DDX6
PRPF18	ENSG00000165630.9	713.60060	449.56150	0.66650	5.43710	4.70820	K562	PUS1
PRPF18	ENSG00000165630.9	473.13810	319.26760	0.56740	5.10380	4.48180	HepG2	SRFBP1
PRPF18	ENSG00000165630.9	419.91460	221.10300	0.92530	4.73990	3.83100	HepG2	RAVER1
PRPF18	ENSG00000165630.9	422.25620	295.66800	0.51400	4.39000	3.74270	HepG2	ZNF622
PRPF18	ENSG00000165630.9	415.83010	282.66940	0.55680	4.10580	3.50660	HepG2	RBM22
PRPF18	ENSG00000165630.9	373.44270	231.42310	0.69030	4.10620	3.19230	K562	PRPF8
PRPF18	ENSG00000165630.9	375.39230	260.94330	0.52460	3.58710	2.91230	K562	FXR1
PRPF18	ENSG00000165630.9	991.58280	726.33840	0.44900	3.34930	2.45240	K562	PUF60
PRPF18	ENSG00000165630.9	102.22760	177.10880	-0.79290	3.30500	2.31550	HepG2	GEMIN5
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 31 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PRPF18 is not available on ENCORE database.

12 RBPs can affect the splicing of PRPF18 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	0.12600	0.00000	0.00018	included	HepG2	SFPQ
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.08300	0.00004	0.00104	excluded	K562	PUS1
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.08700	0.00013	0.00537	excluded	K562	AGGF1
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	0.09000	0.00016	0.03350	included	K562	DROSHA
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.09200	0.00023	0.00989	excluded	K562	AKAP8L
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	0.10800	0.00084	0.05255	included	HepG2	FTO
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.11500	0.00101	0.02566	excluded	HepG2	SRSF1
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	0.15300	0.00172	0.06265	included	HepG2	MATR3
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.12100	0.00219	0.07208	excluded	K562	PTBP1
SE	PRPF18	ENSG00000165630.9	chr10	+	13633767	13633888	13628938	13629152	13639457	13639535	-0.07200	0.00229	0.06301	excluded	K562	UTP18

Showing 1 to 10 of 12 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PRPF18

General Information

Functions

Localization

Domains (AlphaFold: PRPF18)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PRPF18 is not avaliable on ENCORE database.

6 proteins are bound to PRPF18 RNA:

eCLIP assay for PRPF18 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PRPF18 is not available on ENCORE database.

31 RBPs can affect the gene expression of PRPF18 :

The Knockdown/knockout RNA-Seq assay for PRPF18 is not available on ENCORE database.

12 RBPs can affect the splicing of PRPF18 :

The Knockdown/knockout RNA-Seq assay for PRPF18 is not avaliable on ENCORE database.