NAE1

General Information

Gene Name : NAE1
Gene ID : ENSG00000159593.14
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: NAE1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	NAE1	ENSG00000159593.14	53.05	48.44	50.74	ENCSR000AEF
HepG2	NAE1	ENSG00000159593.14	61.12	126.94	94.03	ENCSR985KAT
K562	NAE1	ENSG00000159593.14	118.72	136.54	127.63	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for NAE1 is not avaliable on ENCORE database.

Proteins bound to RNA

NAE1 RNA is bound by 30 proteins.

CanvasJS.com

eCLIP assay for NAE1 is not avaliable on ENCORE database.

30 proteins are bound to NAE1 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	66836832	66836860	-	3'-UTR,intron-Distal	8.06845	87.51345	HepG2	SUB1
chr16	66836860	66836887	-	3'-UTR,intron-Distal	7.82619	75.17515	HepG2	SUB1
chr16	66836804	66836832	-	3'-UTR,intron-Distal,intron-Proximal	6.63065	40.87653	HepG2	SUB1
chr16	66839144	66839200	-	intron-Distal	6.87530	31.98927	HepG2	QKI
chr16	66864702	66864766	-	5'-UTR,CDS,intron-Distal	7.14750	27.81167	HepG2	PRPF8
chr16	66858736	66858815	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.48935	24.72400	HepG2	U2AF2
chr16	66839200	66839243	-	intron-Distal	6.48704	24.70513	HepG2	QKI
chr16	66843492	66843591	-	intron-Distal	5.53105	24.14498	HepG2	QKI
chr16	66850515	66850573	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.98565	20.22136	HepG2	BCLAF1
chr16	66836827	66836915	-	3'-UTR,intron-Distal	5.16309	19.70746	K562	NOLC1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 105 entries

eCLIP assay for NAE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for NAE1 is not available on ENCORE database.
87 RBPs can affect the levels of NAE1.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for NAE1 is not available on ENCORE database.

87 RBPs can affect the gene expression of NAE1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
NAE1	ENSG00000159593.10	2762.28730	5439.30120	-0.97760	23.02520	21.51500	K562	AQR
NAE1	ENSG00000159593.10	2460.16530	3828.50460	-0.63800	21.74330	19.96700	K562	UPF1
NAE1	ENSG00000159593.10	1409.33120	2655.35120	-0.91390	20.31680	18.78170	K562	HNRNPC
NAE1	ENSG00000159593.10	976.59860	1608.92240	-0.72030	18.09690	16.61730	HepG2	UPF1
NAE1	ENSG00000159593.10	1195.43340	1967.26750	-0.71870	17.99820	16.50060	HepG2	SRSF7
NAE1	ENSG00000159593.10	900.46100	1788.16560	-0.98970	14.95250	13.64500	HepG2	EIF2S1
NAE1	ENSG00000159593.10	1458.22220	2507.91280	-0.78230	14.59820	13.37600	HepG2	PUF60
NAE1	ENSG00000159593.10	1838.07170	3121.00570	-0.76380	14.11790	12.29550	K562	GPKOW
NAE1	ENSG00000159593.10	952.31240	1575.33020	-0.72610	13.16950	12.21640	HepG2	TIAL1
NAE1	ENSG00000159593.10	1048.54930	1589.33310	-0.60000	12.86440	11.77380	HepG2	TRIM56
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 110 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for NAE1 is not available on ENCORE database.

19 RBPs can affect the splicing of NAE1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	NAE1	ENSG00000159593.10	chr16	-	66861882	66861980			66860579	66860683	66864749	66864879	-0.08100	0.00003	excluded	K562	PRPF8
SE	NAE1	ENSG00000159593.10	chr16	-	66858757	66858788			66857431	66857503	66860425	66860486	-0.36900	0.00011	excluded	HepG2	U2AF1
SE	NAE1	ENSG00000159593.10	chr16	-	66860579	66860683			66860425	66860486	66864749	66864879	-0.08600	0.00000	excluded	K562	AQR
SE	NAE1	ENSG00000159593.10	chr16	-	66858757	66858788			66857431	66857503	66860425	66860486	-0.19300	0.00000	excluded	K562	U2AF1
SE	NAE1	ENSG00000159593.10	chr16	-	66850867	66850931			66850483	66850575	66851327	66851390	-0.05500	0.00000	excluded	K562	U2AF2
SE	NAE1	ENSG00000159593.10	chr16	-	66858757	66858788			66857431	66857503	66860425	66860486	-0.18300	0.00000	excluded	K562	TARDBP
SE	NAE1	ENSG00000159593.10	chr16	-	66860579	66860683			66860425	66860486	66864749	66864879	-0.11400	0.00000	excluded	K562	TARDBP
A3SS	NAE1	ENSG00000159593.10	chr16	-	66836814	66837063			66836814	66837021	66839679	66839729	0.13500	0.00000	longer	K562	AQR
MXE	NAE1	ENSG00000159593.10	chr16	-	66857431	66857503	66860425	66860486	66857129	66857209	66864749	66864871	0.10700	0.00000	1included	K562	AQR
MXE	NAE1	ENSG00000159593.10	chr16	-	66857129	66857209	66857431	66857503	66855348	66855462	66860425	66860486	0.11200	0.00000	1included	K562	TARDBP

Showing 1 to 10 of 40 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

NAE1

General Information

Functions

Localization

Domains (AlphaFold: NAE1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for NAE1 is not avaliable on ENCORE database.

30 proteins are bound to NAE1 RNA:

eCLIP assay for NAE1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for NAE1 is not available on ENCORE database.

87 RBPs can affect the gene expression of NAE1 :

The Knockdown/knockout RNA-Seq assay for NAE1 is not available on ENCORE database.

19 RBPs can affect the splicing of NAE1 :

The Knockdown/knockout RNA-Seq assay for NAE1 is not avaliable on ENCORE database.