STAU2

General Information

Gene Name : STAU2
Gene ID : ENSG00000040341.17
Essential Gene : No

Functions

RNA stability & decay
RNA localization
Viral RNA regulation

Localization

Not Available

Domains (AlphaFold: STAU2)

dRBM

Antibody Validation

MBLI: RN013P

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	STAU2	ENSG00000040341.17	39.15	39.93	39.54	ENCSR000AEF
HepG2	STAU2	ENSG00000040341.17	15.31	27.39	21.35	ENCSR985KAT
K562	STAU2	ENSG00000040341.17	27.57	31.64	29.61	ENCSR000AEO

Assays

5 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 593	ENCSR979EWD	STAU2	HepG2	Released	ENCAB995HZA	ENCSR701QEP
knockdown followed by RNA-seq	STAU2-BGKcLV11-K562	ENCSR898KNS	STAU2	K562	Released		ENCSR292PXV	CRISPR	KD% = 75.3,61.8
knockdown followed by RNA-seq	STAU2-BGHcLV10-HepG2	ENCSR279MNU	STAU2	HepG2	Released		ENCSR775ZWO	CRISPR	KD% = 96.5,98.7
knockdown followed by RNA-seq	STAU2-BG293LV05-WT293		STAU2	293T	Released			shRNA	KD% = ,
knockdown followed by RNA-seq	STAU2-BG293LV06-WT293		STAU2	293T	Released			shRNA	KD% = ,

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
STAU2	593	HepG2	ENCSR979EWD	ENCSR701QEP	ENCAB995HZA	RN013P	1	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
STAU2	ENCAB995HZA	RN013P	1		Released, ENCODE3		Released, ENCODE3	BGKcLV11-101, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
STAU2	K562	CRISPR			BGKcLV11-99,BGKcLV11-100	BGKcLV11-1,BGKcLV11-2	49.7,66.4	NotSatisfied	ENCODE4
STAU2	K562	CRISPR	ENCSR898KNS	ENCSR292PXV	STAU2-BGKcLV11-101,STAU2-BGKcLV11-102	NT-BGKcLV11-1,NT-BGKcLV11-2	75.3,61.8	Released	ENCODE4
STAU2	HepG2	CRISPR			BGHcLV10-43,BGHcLV10-44	BGHcLV10-1,BGHcLV10-2	80.1,81.5	NotSatisfied	ENCODE4
STAU2	HepG2	CRISPR	ENCSR279MNU	ENCSR775ZWO	STAU2-BGHcLV10-45,STAU2-BGHcLV10-46	NT-BGHcLV10-1,NT-BGHcLV10-2	96.5,98.7	Released	ENCODE4
STAU2	293T	shRNA			STAU2-BG293LV05-57,STAU2-BG293LV05-58	NT-BG293LV05-1,NT-BG293LV05-2	,	Released	ENCORE2
STAU2	293T	shRNA			BG293LV05-59,BG293LV05-60	BG293LV05-1,BG293LV05-2		NotSatisfied	ENCORE2
STAU2	293T	shRNA			STAU2-BG293LV06-81B,STAU2-BG293LV06-82B	NT-BG293LV06-1B,NT-BG293LV06-2B	,	Released	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
STAU2	Product_ID: RN013P Lot_ID: 1 Source: MBLI Target Name: STAU2-human

RNA Targets

STAU2 protein binds to 772 RNA regions.

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Proteins bound to RNA

STAU2 RNA is bound by 27 proteins.

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STAU2 protein has 772 RNA targets:

Only display 100 entries as example. Please click "View All" button to see all 772 entries.

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RBP	Chr	Start	End	Strand	log2(fold change)	-log(p-value)	Cell Line	Matched Gene	Matched Area
STAU2	chr11	2152435	2152447	-	3.02116	400.00000	HepG2	IGF2	3'-UTR,intron-Distal
STAU2	chr11	2152664	2152666	-	5.19220	400.00000	HepG2	IGF2	3'-UTR,intron-Distal
STAU2	chr11	2152646	2152656	-	4.95474	400.00000	HepG2	IGF2	3'-UTR,intron-Distal
STAU2	chr11	2152722	2152727	-	4.89641	400.00000	HepG2	IGF2	3'-UTR,intron-Distal
STAU2	chr11	2152549	2152555	-	3.26166	400.00000	HepG2	IGF2	3'-UTR,intron-Distal
STAU2	chr17	79477500	79477563	-	3.00992	37.03803	HepG2	ACTG1	3'-UTR,intron-Distal,intron-Proximal
STAU2	chr16	67904918	67904936	+	5.03804	27.20718	HepG2	NUTF2	3'-UTR
STAU2	chr19	2273006	2273028	+	4.92790	25.74079	HepG2	OAZ1	3'-UTR,CDS
STAU2	chr2	70505437	70505465	+	4.31913	20.98410	HepG2	PCYOX1	3'-UTR
STAU2	chr14	95058818	95058856	+	3.70638	18.69482	HepG2	SERPINA5, RP11-986E7.7	3'-UTR,intron-Distal

Showing 1 to 10 of 100 entries

27 proteins are bound to STAU2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr8	74658702	74658767	-	intron-Distal	4.51381	15.31488	HepG2	FAM120A
chr8	74658586	74658688	-	intron-Distal	4.36239	15.27355	K562	CSTF2T
chr8	74658437	74658511	-	intron-Distal	5.28795	15.23154	HepG2	FAM120A
chr8	74658437	74658548	-	intron-Distal	4.36403	14.82168	K562	CSTF2T
chr8	74658224	74658298	-	intron-Distal	3.95916	14.70410	K562	CSTF2T
chr8	74658323	74658395	-	intron-Distal	5.65225	13.82196	K562	CSTF2T
chr8	74658444	74658550	-	intron-Distal	5.46595	12.38643	HepG2	PRPF4
chr8	74658566	74658655	-	intron-Distal	4.69220	12.15448	HepG2	FAM120A
chr8	74658672	74658764	-	intron-Distal	4.56064	12.10411	HepG2	PRPF4
chr8	74658583	74658654	-	intron-Distal	4.53298	11.91445	K562	DROSHA
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 110 entries

No autoregularoty interactions between protein STAU2 and its RNA.

Diffrential Expression

The Knockdown/knockout assay for STAU2 is not available on ENCORE database.
56 RBPs can affect the levels of STAU2.

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The Knockdown/knockout RNA-Seq assay for STAU2 is not available on ENCORE database.

56 RBPs can affect the gene expression of STAU2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
STAU2	ENSG00000040341.13	1560.65350	927.79740	0.75020	19.15020	18.14290	HepG2	SRFBP1
STAU2	ENSG00000040341.13	492.99520	888.19900	-0.84930	18.32060	17.22000	HepG2	ZNF622
STAU2	ENSG00000040341.13	783.73740	1401.36410	-0.83840	12.09980	10.99860	K562	AQR
STAU2	ENSG00000040341.13	456.64270	746.10050	-0.70830	10.11510	9.07150	HepG2	PCBP1
STAU2	ENSG00000040341.13	404.41490	611.17410	-0.59570	6.68070	5.77590	HepG2	HNRNPU
STAU2	ENSG00000040341.13	400.35990	599.17960	-0.58170	6.52110	5.72100	HepG2	TRIM56
STAU2	ENSG00000040341.13	561.16990	863.07640	-0.62110	6.42300	5.55090	K562	HNRNPC
STAU2	ENSG00000040341.13	599.63780	937.62820	-0.64490	5.94760	4.75370	K562	EIF4A3
STAU2	ENSG00000040341.13	1290.93950	961.00620	0.42570	5.49770	4.53500	K562	EIF2S2
STAU2	ENSG00000040341.13	771.64120	1163.41880	-0.59240	5.47530	4.48730	K562	SRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 66 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for STAU2 is not available on ENCORE database.

11 RBPs can affect the splicing of STAU2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397			74600885	74601048	74650518	74650584	-0.19500	0.00000	0.00003	excluded	K562	AKAP8L
SE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397			74600885	74601048	74650518	74650584	-0.26800	0.00000	0.00000	excluded	K562	PUS1
SE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397			74600885	74601048	74650518	74650584	0.17700	0.00000	0.00065	included	HepG2	LARP4
SE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397			74600885	74601048	74650518	74650584	-0.19000	0.00000	0.00002	excluded	K562	UTP18
SE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397			74600885	74601048	74650518	74650584	-0.23900	0.00000	0.00000	excluded	K562	RBM15
SE	STAU2	ENSG00000040341.13	chr8	-	74473645	74473774			74464130	74464554	74495004	74495065	0.14100	0.00000	0.00018	included	K562	HNRNPC
MXE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397	74650518	74650584	74600888	74601048	74651990	74652103	0.14900	0.00000	0.00000	1included	K562	RBM15
MXE	STAU2	ENSG00000040341.13	chr8	-	74621266	74621397	74650518	74650584	74600888	74601048	74651990	74652103	0.14400	0.00000	0.00000	1included	K562	PUS1
SE	STAU2	ENSG00000040341.13	chr8	-	74439925	74440039			74334848	74334937	74464246	74464554	0.54000	0.00001	0.00050	included	HepG2	SRSF1
SE	STAU2	ENSG00000040341.13	chr8	-	74473645	74473774			74464130	74464554	74495004	74495065	0.06100	0.00001	0.00081	included	K562	SF3B1

Showing 1 to 10 of 19 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

STAU2

General Information

Functions

Localization

Domains (AlphaFold: STAU2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

STAU2 protein has 772 RNA targets:

27 proteins are bound to STAU2 RNA:

No autoregularoty interactions between protein STAU2 and its RNA.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for STAU2 is not available on ENCORE database.

56 RBPs can affect the gene expression of STAU2 :

The Knockdown/knockout RNA-Seq assay for STAU2 is not available on ENCORE database.

11 RBPs can affect the splicing of STAU2 :

The Knockdown/knockout RNA-Seq assay for STAU2 is not avaliable on ENCORE database.