PMM2

General Information

Gene Name : PMM2
Gene ID : ENSG00000140650.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PMM2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PMM2	ENSG00000140650.11	68.12	47.24	57.68	ENCSR000AEF
HepG2	PMM2	ENSG00000140650.11	41.98	66.50	54.24	ENCSR985KAT
K562	PMM2	ENSG00000140650.11	19.62	22.84	21.23	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PMM2 is not avaliable on ENCORE database.

Proteins bound to RNA

PMM2 RNA is bound by 33 proteins.

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eCLIP assay for PMM2 is not avaliable on ENCORE database.

33 proteins are bound to PMM2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	8895673	8895777	+	5'-UTR,CDS,intron-Proximal	3.44183	45.97564	HepG2	PPIG
chr16	8943182	8943283	+	3'-UTR,polyA_site	6.51280	38.15681	K562	FMR1
chr16	8941550	8941590	+	3'-UTR,CDS,intron-Proximal	5.54762	27.16101	HepG2	SF3A3
chr16	8905497	8905572	+	3'-UTR,5'-UTR,CDS,intron-Proximal	4.74058	24.01951	HepG2	BCLAF1
chr16	8904935	8905037	+	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.90638	22.57466	HepG2	BCLAF1
chr16	8895660	8895775	+	5'-UTR,CDS,intron-Proximal	3.26350	21.51811	HepG2	BCLAF1
chr16	8941543	8941550	+	intron-Proximal	5.64020	21.09608	HepG2	SF3A3
chr16	8906860	8906927	+	3'-UTR,5'-UTR,CDS	3.73054	18.76912	HepG2	BCLAF1
chr16	8900215	8900269	+	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.12944	18.57216	HepG2	BCLAF1
chr16	8906864	8906931	+	3'-UTR,5'-UTR,CDS	3.93346	16.20045	HepG2	PPIG
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 102 entries

eCLIP assay for PMM2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PMM2 is not available on ENCORE database.
99 RBPs can affect the levels of PMM2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for PMM2 is not available on ENCORE database.

99 RBPs can affect the gene expression of PMM2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PMM2	ENSG00000140650.7	1539.02720	2773.63410	-0.84980	28.68660	27.09220	HepG2	ETF1
PMM2	ENSG00000140650.7	2959.13700	1856.13300	0.67280	26.63100	25.37530	HepG2	ZNF622
PMM2	ENSG00000140650.7	468.95920	1282.49520	-1.45140	24.04850	22.41040	HepG2	SUPV3L1
PMM2	ENSG00000140650.7	856.46010	348.07070	1.29890	22.64620	20.04570	K562	EIF4A3
PMM2	ENSG00000140650.7	962.29880	357.89250	1.42690	20.83330	18.62720	K562	RPS19
PMM2	ENSG00000140650.7	788.67840	1425.74440	-0.85420	18.41250	17.15070	HepG2	TAF15
PMM2	ENSG00000140650.7	1157.39260	648.70540	0.83510	18.01950	16.36230	K562	UPF1
PMM2	ENSG00000140650.7	1336.80600	776.97400	0.78280	17.14970	15.64740	K562	DDX47
PMM2	ENSG00000140650.7	815.64300	419.83640	0.95800	14.94760	13.46940	K562	PTBP1
PMM2	ENSG00000140650.7	250.14630	524.39070	-1.06790	14.27590	13.09040	K562	AGGF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 115 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PMM2 is not available on ENCORE database.

10 RBPs can affect the splicing of PMM2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	PMM2	ENSG00000140650.7	chr16	+	8896117	8896246			8895655	8895767	8898623	8898700	0.16900	0.00000	0.00000	included	HepG2	HNRNPK
MXE	PMM2	ENSG00000140650.7	chr16	+	8896117	8896246	8898623	8898700	8895655	8895767	8900172	8900264	0.08900	0.00000	0.00000	1included	HepG2	HNRNPK
MXE	PMM2	ENSG00000140650.7	chr16	+	8898623	8898700	8900172	8900264	8895655	8895767	8905494	8905570	-0.13200	0.00003	0.00389	2included	HepG2	BCCIP
MXE	PMM2	ENSG00000140650.7	chr16	+	8900172	8900264	8904935	8905035	8895655	8895767	8905494	8905570	0.26600	0.00020	0.00556	1included	K562	HNRNPC
SE	PMM2	ENSG00000140650.7	chr16	+	8896117	8896246			8895655	8895767	8898623	8898700	0.17900	0.00022	0.01414	included	K562	HNRNPK
SE	PMM2	ENSG00000140650.7	chr16	+	8898623	8898700			8895655	8895767	8900172	8900891	0.06200	0.00035	0.03115	included	HepG2	IGF2BP3
MXE	PMM2	ENSG00000140650.7	chr16	+	8900172	8900264	8904935	8905035	8895655	8895767	8905494	8905570	-0.10600	0.00035	0.04880	2included	HepG2	HNRNPA1
MXE	PMM2	ENSG00000140650.7	chr16	+	8900172	8900264	8904935	8905035	8895655	8895767	8905494	8905570	-0.09000	0.00047	0.03804	2included	HepG2	IGF2BP3
MXE	PMM2	ENSG00000140650.7	chr16	+	8900172	8900264	8904935	8905035	8895655	8895767	8905494	8905570	-0.13900	0.00094	0.05130	2included	HepG2	XPO5
SE	PMM2	ENSG00000140650.7	chr16	+	8898623	8898700			8895655	8895767	8900172	8900891	0.05600	0.00259	0.05357	included	HepG2	SRSF1

Showing 1 to 10 of 15 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PMM2

General Information

Functions

Localization

Domains (AlphaFold: PMM2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PMM2 is not avaliable on ENCORE database.

33 proteins are bound to PMM2 RNA:

eCLIP assay for PMM2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PMM2 is not available on ENCORE database.

99 RBPs can affect the gene expression of PMM2 :

The Knockdown/knockout RNA-Seq assay for PMM2 is not available on ENCORE database.

10 RBPs can affect the splicing of PMM2 :

The Knockdown/knockout RNA-Seq assay for PMM2 is not avaliable on ENCORE database.