EIF3L

General Information

Gene Name : EIF3L
Gene ID : ENSG00000100129.17
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EIF3L)

Not Available

Antibody Validation

View validation images for all EIF3L antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EIF3L	ENSG00000100129.17	556.01	532.59	544.30	ENCSR000AEF
HepG2	EIF3L	ENSG00000100129.17	337.67	302.43	320.05	ENCSR985KAT
K562	EIF3L	ENSG00000100129.17	285.55	340.33	312.94	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
EIF3L		A304-753A	1					BGKcLV38-55, Submitted, ENCORE2
EIF3L		A304-754A	1				BGHcLV39-61, Submitted, ENCORE2	BGKcLV38-55, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
EIF3L	K562	CRISPR			EIF3L-BGKcLV38-55,EIF3L-BGKcLV38-56	NT-BGKcLV38-1,NT-BGKcLV38-2	77.2,79.6	Submitting	ENCORE2
EIF3L	HepG2	CRISPR			EIF3L-BGHcLV39-61,EIF3L-BGHcLV39-62	NT-BGHcLV39-1,NT-BGHcLV39-2	80.2,76.1	Submitting	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
EIF3L	Product_ID: A304-753A Lot_ID: 1 Source: Bethyl Labs Target Name: EIF3L-human
EIF3L	Product_ID: A304-754A Lot_ID: 1 Source: Bethyl Labs Target Name: EIF3L-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EIF3L is not avaliable on ENCORE database.

Proteins bound to RNA

EIF3L RNA is bound by 21 proteins.

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eCLIP assay for EIF3L is not avaliable on ENCORE database.

21 proteins are bound to EIF3L RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr22	38258977	38258997	+	3'-UTR,CDS,intron-Distal	4.83738	79.99366	K562	YBX3
chr22	38254727	38254744	+	5'-UTR,CDS,intron-Distal	4.63275	73.98105	K562	YBX3
chr22	38254744	38254747	+	5'-UTR,CDS,intron-Distal	4.69718	72.54068	K562	YBX3
chr22	38258975	38258977	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.70219	72.43423	K562	YBX3
chr22	38254714	38254727	+	5'-UTR,CDS,intron-Distal	5.18300	52.43427	K562	YBX3
chr22	38271907	38271931	+	CDS	3.09204	45.92180	K562	YBX3
chr22	38273973	38274042	+	CDS	3.11232	39.48009	K562	YBX3
chr22	38271940	38271954	+	CDS	3.14034	39.33938	K562	YBX3
chr22	38270429	38270475	+	CDS	3.82135	39.21336	K562	YBX3
chr22	38247371	38247455	+	5'-UTR,CDS	5.84137	36.59515	K562	IGF2BP1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 131 entries

eCLIP assay for EIF3L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EIF3L is not available on ENCORE database.
118 RBPs can affect the levels of EIF3L.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for EIF3L is not available on ENCORE database.

118 RBPs can affect the gene expression of EIF3L :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EIF3L	ENSG00000100129.13	5324.39450	12753.58880	-1.26020	67.61710	65.99240	HepG2	SRSF1
EIF3L	ENSG00000100129.13	4750.98850	11735.52060	-1.30460	65.01890	63.18520	HepG2	PTBP1
EIF3L	ENSG00000100129.13	5423.14530	12218.88690	-1.17190	58.54400	56.51720	HepG2	SF3B4
EIF3L	ENSG00000100129.13	6178.68340	12710.68480	-1.04070	46.42850	44.46590	HepG2	QKI
EIF3L	ENSG00000100129.13	1903.86150	4398.30000	-1.20800	38.84490	37.01370	HepG2	RPS19
EIF3L	ENSG00000100129.13	4661.89750	8323.05120	-0.83620	38.53270	36.38050	K562	DDX47
EIF3L	ENSG00000100129.13	2565.30300	5262.58640	-1.03660	35.59700	34.17290	HepG2	TIAL1
EIF3L	ENSG00000100129.13	5152.04150	12991.78230	-1.33440	33.57230	31.65780	HepG2	DDX3X
EIF3L	ENSG00000100129.13	4621.55660	11280.03620	-1.28730	32.58270	30.58260	HepG2	IGF2BP2
EIF3L	ENSG00000100129.13	4902.86940	12316.67090	-1.32890	31.76200	29.80270	HepG2	NCBP2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 137 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EIF3L is not available on ENCORE database.

11 RBPs can affect the splicing of EIF3L :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	EIF3L	ENSG00000100129.13	chr22	+	38246021	38246070	38245417	38245489	38247286	38247497	-0.12500	0.00000	excluded	K562	SF3B4
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.11700	0.00000	excluded	K562	SF3B4
SE	EIF3L	ENSG00000100129.13	chr22	+	38246021	38246070	38245417	38245489	38247286	38247497	-0.05700	0.00012	excluded	HepG2	U2AF1
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.17100	0.00000	excluded	HepG2	U2AF1
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.06400	0.00000	excluded	K562	XRCC6
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.12200	0.00000	excluded	HepG2	U2AF2
SE	EIF3L	ENSG00000100129.13	chr22	+	38246021	38246070	38245426	38245489	38247286	38247497	-0.07200	0.00000	excluded	K562	AQR
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.05800	0.00000	excluded	K562	AQR
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.05200	0.00257	excluded	K562	GPKOW
SE	EIF3L	ENSG00000100129.13	chr22	+	38251571	38251651	38247286	38247497	38254685	38254747	-0.06600	0.00000	excluded	K562	U2AF1

Showing 1 to 10 of 17 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EIF3L

General Information

Functions

Localization

Domains (AlphaFold: EIF3L)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EIF3L is not avaliable on ENCORE database.

21 proteins are bound to EIF3L RNA:

eCLIP assay for EIF3L is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EIF3L is not available on ENCORE database.

118 RBPs can affect the gene expression of EIF3L :

The Knockdown/knockout RNA-Seq assay for EIF3L is not available on ENCORE database.

11 RBPs can affect the splicing of EIF3L :

The Knockdown/knockout RNA-Seq assay for EIF3L is not avaliable on ENCORE database.