CLCN3

General Information

Gene Name : CLCN3
Gene ID : ENSG00000109572.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CLCN3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CLCN3	ENSG00000109572.13	17.64	10.88	14.26	ENCSR000AEF
HepG2	CLCN3	ENSG00000109572.13	13.86	20.01	16.94	ENCSR985KAT
K562	CLCN3	ENSG00000109572.13	25.38	29.31	27.34	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CLCN3 is not avaliable on ENCORE database.

Proteins bound to RNA

CLCN3 RNA is bound by 21 proteins.

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eCLIP assay for CLCN3 is not avaliable on ENCORE database.

21 proteins are bound to CLCN3 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	170641662	170641750	+	3'-UTR	5.61841	28.76274	K562	PTBP1
chr4	170639926	170640062	+	intron-Distal	6.43352	22.23673	K562	QKI
chr4	170608979	170609033	+	intron-Distal,intron-Proximal	4.42480	12.95470	K562	U2AF2
chr4	170581636	170581700	+	intron-Distal,intron-Proximal	5.33457	11.36415	K562	RBFOX2
chr4	170609148	170609293	+	intron-Distal	3.81908	10.91503	K562	KHSRP
chr4	170641569	170641638	+	3'-UTR	4.52120	10.51368	K562	IGF2BP1
chr4	170541737	170541853	+	5'-UTR,intron-Distal,intron-Proximal	3.63882	10.26041	HepG2	DDX3X
chr4	170541784	170541843	+	5'-UTR,intron-Distal,intron-Proximal	3.81729	9.45490	K562	DDX3X
chr4	170575351	170575468	+	intron-Distal	4.21147	9.12099	HepG2	PTBP1
chr4	170639916	170640059	+	intron-Distal	5.47475	9.03229	HepG2	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 44 entries

eCLIP assay for CLCN3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CLCN3 is not available on ENCORE database.
122 RBPs can affect the levels of CLCN3.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for CLCN3 is not available on ENCORE database.

122 RBPs can affect the gene expression of CLCN3 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CLCN3	ENSG00000109572.9	3286.02240	1829.05040	0.84510	35.18640	33.92800	HepG2	SRFBP1
CLCN3	ENSG00000109572.9	2440.82020	1200.80210	1.02330	34.85810	33.32350	HepG2	SRSF9
CLCN3	ENSG00000109572.9	2572.94480	1525.35990	0.75420	30.05620	28.52710	HepG2	PUM1
CLCN3	ENSG00000109572.9	2988.75950	1619.41020	0.88400	27.13780	25.84700	HepG2	RBM22
CLCN3	ENSG00000109572.9	1666.63090	3050.87580	-0.87230	27.48160	25.21450	K562	SF3A3
CLCN3	ENSG00000109572.9	4177.25460	1155.50120	1.85390	26.48570	24.53210	HepG2	RAVER1
CLCN3	ENSG00000109572.9	2742.09970	1613.50950	0.76500	24.13530	22.59250	HepG2	SUCLG1
CLCN3	ENSG00000109572.9	2847.26980	5789.75230	-1.02390	24.12320	22.52790	K562	PUS1
CLCN3	ENSG00000109572.9	3293.64950	5641.21130	-0.77630	23.60210	21.79810	K562	RBM15
CLCN3	ENSG00000109572.9	1836.02390	1090.91010	0.75100	21.65010	20.31010	HepG2	ACO1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 144 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CLCN3 is not available on ENCORE database.

6 RBPs can affect the splicing of CLCN3 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CLCN3	ENSG00000109572.9	chr4	+	170638942	170639018			170634229	170634446	170641057	170641696	0.24700	0.00000	0.00000	included	K562	SRSF1
A3SS	CLCN3	ENSG00000109572.9	chr4	+	170634195	170634338			170634229	170634338	170628018	170628417	0.11200	0.00000	0.00000	longer	K562	AQR
SE	CLCN3	ENSG00000109572.9	chr4	+	170608816	170608908			170601218	170601358	170610193	170610381	-0.08500	0.00001	0.00032	excluded	K562	PUS1
A3SS	CLCN3	ENSG00000109572.9	chr4	+	170616745	170616843			170616762	170616843	170613264	170613471	0.07400	0.00001	0.00011	longer	K562	AQR
A3SS	CLCN3	ENSG00000109572.9	chr4	+	170608787	170608908			170608808	170608908	170601200	170601358	0.05800	0.00001	0.00006	longer	K562	AQR
SE	CLCN3	ENSG00000109572.9	chr4	+	170608808	170608908			170601200	170601358	170610193	170610381	-0.05100	0.00004	0.00078	excluded	K562	AQR
A3SS	CLCN3	ENSG00000109572.9	chr4	+	170613232	170613471			170613264	170613471	170611680	170611803	0.05500	0.00012	0.00106	longer	K562	AQR
SE	CLCN3	ENSG00000109572.9	chr4	+	170638942	170639018			170634229	170634446	170641057	170641696	0.12500	0.00029	0.03380	included	HepG2	DDX59
SE	CLCN3	ENSG00000109572.9	chr4	+	170638942	170639018			170634229	170634446	170641057	170641696	0.12400	0.00035	0.01674	included	K562	TARDBP
MXE	CLCN3	ENSG00000109572.9	chr4	+	170618339	170618476	170618746	170618885	170616699	170616843	170634229	170634446	-0.07400	0.00116	0.01039	2included	K562	AQR

Showing 1 to 10 of 13 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CLCN3

General Information

Functions

Localization

Domains (AlphaFold: CLCN3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CLCN3 is not avaliable on ENCORE database.

21 proteins are bound to CLCN3 RNA:

eCLIP assay for CLCN3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CLCN3 is not available on ENCORE database.

122 RBPs can affect the gene expression of CLCN3 :

The Knockdown/knockout RNA-Seq assay for CLCN3 is not available on ENCORE database.

6 RBPs can affect the splicing of CLCN3 :

The Knockdown/knockout RNA-Seq assay for CLCN3 is not avaliable on ENCORE database.