WBP4

General Information

Gene Name       : WBP4
Gene ID             : ENSG00000120688.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WBP4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WBP4ENSG00000120688.814.7114.6714.69ENCSR000AEF
HepG2WBP4ENSG00000120688.87.6012.4310.02ENCSR985KAT
K562WBP4ENSG00000120688.88.138.198.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
WBP4Ribo-STAMP-293TshRNABGRSLV05-41,BGRSLV05-42BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
WBP4Ribo-STAMP-293TshRNAWBP4-BGRSLV08-3,WBP4-BGRSLV08-4NT-BGRSLV08-1,NT-BGRSLV08-2,SubmittedENCORE2
WBP4Ribo-STAMP-293TshRNABGRSDLV03-41,BGRSDLV03-42BGRSDLV03-1,BGRSDLV03-2SubmittedENCORE2
WBP4Ribo-STAMP-293TshRNAWBP4-BGRSDLV03-43dox,WBP4-BGRSDLV03-44doxWBP4-BGRSDLV03-41,WBP4-BGRSDLV03-42,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WBP4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WBP4 RNA is bound by 9 proteins.  







eCLIP assay for WBP4 is not avaliable on ENCORE database.





9 proteins are bound to WBP4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr134165705341657109+3'-UTR4.885066.34419K562PUM2
chr134163569541635812+5'-UTR,CDS,intron-Proximal3.198835.59833HepG2GRWD1
chr134163568841635799+5'-UTR3.322076.01432HepG2PRPF4
chr134163570541635771+5'-UTR3.393375.21025HepG2PPIG
chr134163576541635882+5'-UTR,CDS,intron-Proximal3.560765.62957HepG2BUD13
chr134163568041635788+5'-UTR4.083466.62281HepG2NCBP2
chr134163930941639390+CDS4.563894.21675K562ZNF622
chr134164280041642861+CDS3.996853.36385K562UCHL5
chr134163933441639407+CDS3.955853.80193HepG2GRWD1
chr134164280441642864+CDS3.599413.27569HepG2BCLAF1
chr134163929941639418+CDS,intron-Proximal5.197687.89689K562UCHL5
chr134163936641639411+CDS4.422593.38968HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WBP4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WBP4 is not available on ENCORE database.

  • 42 RBPs can affect the levels of WBP4.  








The Knockdown/knockout RNA-Seq assay for WBP4 is not available on ENCORE database.





42 RBPs can affect the gene expression of WBP4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WBP4ENSG00000120688.7576.54420430.583800.421003.798903.10770HepG2ACO1
WBP4ENSG00000120688.7789.37660583.136700.436802.419501.91870HepG2AKAP1
WBP4ENSG00000120688.7287.03090430.49490-0.584805.410704.53820HepG2CKAP4
WBP4ENSG00000120688.7414.70190553.01100-0.415203.935403.07600HepG2DAZAP1
WBP4ENSG00000120688.7731.90150558.613200.389702.200001.63570HepG2DDX3X
WBP4ENSG00000120688.7396.13150503.77380-0.346802.768702.09470HepG2HNRNPL
WBP4ENSG00000120688.7287.07840375.25880-0.386402.366201.80250HepG2HNRNPU
WBP4ENSG00000120688.7590.76610823.76370-0.479602.842402.00190HepG2LARP4
WBP4ENSG00000120688.7352.10670488.63870-0.472803.664202.98670HepG2PCBP1
WBP4ENSG00000120688.7374.81510523.43690-0.481803.422802.76950HepG2PUF60
WBP4ENSG00000120688.7456.97070555.62660-0.282002.247201.70110HepG2PUM1
WBP4ENSG00000120688.7542.15940438.578200.305802.181801.61940HepG2PUS1
WBP4ENSG00000120688.7930.35210423.895201.134008.669507.46600HepG2RAVER1
WBP4ENSG00000120688.7614.87410482.803700.348801.956901.37030HepG2RPLP0
WBP4ENSG00000120688.7338.03610517.62770-0.614705.471504.68820HepG2SF3B4
WBP4ENSG00000120688.7945.76190600.203400.6559010.9553010.13770HepG2SRFBP1
WBP4ENSG00000120688.7464.53840587.75570-0.339402.620802.01190HepG2SUCLG1
WBP4ENSG00000120688.7412.66880581.73230-0.495403.277102.49520HepG2TARDBP
WBP4ENSG00000120688.7388.22410812.15110-1.064902.336401.43770HepG2U2AF2
WBP4ENSG00000120688.7484.75000585.35190-0.272102.022801.53580HepG2ZNF622
WBP4ENSG00000120688.7217.17940411.25970-0.921209.368108.40320K562AGGF1
WBP4ENSG00000120688.7339.68470451.87740-0.411702.459201.54060K562AKAP8
WBP4ENSG00000120688.7215.61550427.92580-0.988908.383207.18410K562AKAP8L
WBP4ENSG00000120688.7324.25540448.98090-0.469502.389301.54540K562ATP5C1
WBP4ENSG00000120688.7398.01800526.41770-0.403402.687801.59810K562CPEB4
WBP4ENSG00000120688.7327.69430434.25230-0.406202.143001.44400K562CPSF6
WBP4ENSG00000120688.7325.33170460.53260-0.501404.117303.01970K562DKC1
WBP4ENSG00000120688.7118.44400189.63000-0.679002.782401.86670K562EFTUD2
WBP4ENSG00000120688.7335.04060448.07120-0.419402.178101.42380K562FIP1L1
WBP4ENSG00000120688.7298.05030171.365200.798405.951305.11350K562FXR1
WBP4ENSG00000120688.7350.30050175.205400.999406.855605.63100K562G3BP2
WBP4ENSG00000120688.7279.74020414.62210-0.567703.088102.25140K562GPKOW
WBP4ENSG00000120688.7285.89500454.16630-0.667704.885203.73110K562KIF1C
WBP4ENSG00000120688.7288.18320434.72450-0.593103.870502.52920K562MAK16
WBP4ENSG00000120688.7355.19920508.77680-0.518403.872902.76810K562MBNL1
WBP4ENSG00000120688.7195.16050356.61300-0.869704.934103.64410K562NAA15
WBP4ENSG00000120688.7218.89170424.44640-0.955408.261007.37180K562PUS1
WBP4ENSG00000120688.7234.42010413.50810-0.818807.481106.53630K562RBM15
WBP4ENSG00000120688.7277.06690164.562000.751503.473002.34080K562RPS3
WBP4ENSG00000120688.7309.52010188.696300.713903.409501.92680K562RRP9
WBP4ENSG00000120688.7193.61040389.64570-1.009003.028001.74950K562SF1
WBP4ENSG00000120688.7243.96950447.24220-0.874402.718801.50430K562SNRNP200
WBP4ENSG00000120688.7263.47370430.28230-0.707602.919701.58190K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WBP4 is not available on ENCORE database.





3 RBPs can affect the splicing of WBP4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWBP4ENSG00000120688.7chr13+416456624164570941642696416428734164691741646993-0.183000.000030.00067excludedHepG2U2AF2
SEWBP4ENSG00000120688.7chr13+416456624164570941642696416428734164691741646993-0.295000.000000.00000excludedK562AQR
SEWBP4ENSG00000120688.7chr13+416391514163921441636757416368524163929941639423-0.115000.004350.04145excludedK562AQR
SEWBP4ENSG00000120688.7chr13+416391514163921441636779416368524163929941639423-0.117000.000190.00427excludedK562PUS1
MXEWBP4ENSG00000120688.7chr13+41646917416469934165017941650373416426964164287341654781416549450.441000.000000.000031includedK562AQR
MXEWBP4ENSG00000120688.7chr13+41646888416469934165017941650373416426964164287341654781416549450.205000.011030.068521includedK562AQR
MXEWBP4ENSG00000120688.7chr13+4164566241645709416469174164699341642696416428734165017941650373-0.213000.019520.090952includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WBP4 is not avaliable on ENCORE database.