IGHMBP2

General Information

Gene Name       : IGHMBP2
Gene ID             : ENSG00000132740.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IGHMBP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IGHMBP2ENSG00000132740.83.606.645.12ENCSR000AEF
HepG2IGHMBP2ENSG00000132740.88.477.107.79ENCSR985KAT
K562IGHMBP2ENSG00000132740.814.9812.6713.82ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq IGHMBP2-BGRSDLV02-RSD293RBPIGHMBP2Ribo-STAMP-293TReleased   shRNAKD% =
knockdown followed by RNA-seq IGHMBP2-BGRSDLV02-RSD293RBPIGHMBP2Ribo-STAMP-293TReleased   shRNAKD% = ,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
IGHMBP2Ribo-STAMP-293TshRNABGRSLV09-19,BGRSLV09-20BGRSLV09-1,BGRSLV09-2NotSatisfiedENCORE2
IGHMBP2Ribo-STAMP-293TshRNABGRSLV09-21,BGRSLV09-22BGRSLV09-1,BGRSLV09-2NotSatisfiedENCORE2
IGHMBP2Ribo-STAMP-293TshRNABGRSDLV02-37,BGRSDLV02-38BGRSDLV02-1,BGRSDLV02-2ReleasedENCORE2
IGHMBP2Ribo-STAMP-293TshRNAIGHMBP2-BGRSDLV02-39dox,IGHMBP2-BGRSDLV02-40doxIGHMBP2-BGRSDLV02-37,IGHMBP2-BGRSDLV02-38,ReleasedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IGHMBP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • IGHMBP2 RNA is bound by 17 proteins.  







eCLIP assay for IGHMBP2 is not avaliable on ENCORE database.





17 proteins are bound to IGHMBP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116868232868682396+3'-UTR,CDS3.220583.17151K562UCHL5
chr116870767768707769+3'-UTR3.516163.06830K562UPF1
chr116867899268679051+3'-UTR,CDS4.292393.77023K562ZNF622
chr116868230168682460+3'-UTR,CDS4.124076.22576HepG2BCLAF1
chr116867905168679121+3'-UTR,CDS,intron-Proximal5.218906.35567HepG2PRPF8
chr116867906168679110+3'-UTR,CDS,intron-Proximal4.091953.12843K562PRPF8
chr116869662868696672+CDS,intron-Proximal4.831153.62536K562AQR
chr116869672568696782+CDS4.305353.45943HepG2BCLAF1
chr116868526868685321+CDS4.054103.38968HepG2BCLAF1
chr116870070268700777+CDS,intron-Proximal3.281983.57857HepG2SF3B4
chr116869669268696744+CDS3.790833.59112HepG2PPIG
chr116868534968685391+CDS,intron-Proximal3.210814.38107K562AQR
chr116868692568686978+intron-Distal4.203653.78162K562HNRNPM
chr116868671268686815+intron-Distal4.5224411.17441HepG2PCBP2
chr116868664168686708+intron-Distal5.022447.38423HepG2PCBP2
chr116869312668693222+intron-Distal3.878483.06015K562MATR3
chr116869711868697256+intron-Distal3.538174.85046K562NONO
chr116869981468699898+intron-Distal4.159043.86024K562EWSR1
chr116869939868699544+intron-Distal4.666096.83853HepG2PRPF4
chr116868665268686810+intron-Distal3.164694.15212HepG2DDX59
chr116869974368699916+intron-Distal4.415195.90426K562FUS
chr116868411768684280+intron-Distal4.930786.92529HepG2RBFOX2
chr116870069068700751+intron-Proximal4.869655.13952K562SF3B4
chr116867150668671549+intron-Proximal4.623633.62536K562AQR
chr116870202668702083+intron-Proximal4.667364.13847K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IGHMBP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IGHMBP2 is not available on ENCORE database.

  • 49 RBPs can affect the levels of IGHMBP2.  








The Knockdown/knockout RNA-Seq assay for IGHMBP2 is not available on ENCORE database.





49 RBPs can affect the gene expression of IGHMBP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IGHMBP2ENSG00000132740.4311.66330197.831700.655602.398401.52720HepG2BCCIP
IGHMBP2ENSG00000132740.4334.32040219.560900.606503.497102.83320HepG2BOP1
IGHMBP2ENSG00000132740.4268.58740195.428400.458702.523701.94470HepG2HNRNPU
IGHMBP2ENSG00000132740.4386.80370207.491500.898404.686803.50920HepG2PABPC1
IGHMBP2ENSG00000132740.4414.91710284.727400.543103.545602.88190HepG2PUF60
IGHMBP2ENSG00000132740.4374.19870302.255800.307901.808101.30590HepG2PUM1
IGHMBP2ENSG00000132740.4289.77330378.72690-0.386202.422701.83580HepG2PUS1
IGHMBP2ENSG00000132740.4312.99470207.929000.589902.800501.99520HepG2RPS2
IGHMBP2ENSG00000132740.4821.01460385.926901.0890010.786809.39060HepG2SF3A3
IGHMBP2ENSG00000132740.4463.09500317.920400.542504.471403.74680HepG2SF3B4
IGHMBP2ENSG00000132740.4358.32940281.133000.349901.938901.40320HepG2SRSF5
IGHMBP2ENSG00000132740.4285.52340198.500300.524402.321001.32880HepG2STIP1
IGHMBP2ENSG00000132740.4408.28610319.720400.352702.180601.61630HepG2SUCLG1
IGHMBP2ENSG00000132740.4190.89790298.34730-0.644203.952303.30130HepG2TAF15
IGHMBP2ENSG00000132740.4317.09020189.881500.739705.249204.60550HepG2TIAL1
IGHMBP2ENSG00000132740.4371.36250278.175000.416702.209301.43440HepG2TUFM
IGHMBP2ENSG00000132740.4633.93340298.829801.0849011.5298010.22060HepG2U2AF1
IGHMBP2ENSG00000132740.4648.28830196.500601.722007.024605.37890HepG2U2AF2
IGHMBP2ENSG00000132740.4473.48920294.449400.685203.974802.96150HepG2UBE2L3
IGHMBP2ENSG00000132740.4196.42920114.357800.780403.303102.47570HepG2UCHL5
IGHMBP2ENSG00000132740.4334.39560204.323700.710603.133001.95870HepG2XPO5
IGHMBP2ENSG00000132740.4566.24420376.418000.589006.952306.18810HepG2ZNF622
IGHMBP2ENSG00000132740.4870.77190644.384800.434304.579203.88080K562AGGF1
IGHMBP2ENSG00000132740.4900.69230708.140500.346902.730501.75610K562AKAP8
IGHMBP2ENSG00000132740.4865.50100670.526100.368102.877602.21150K562AKAP8L
IGHMBP2ENSG00000132740.41216.36580858.491800.502604.886704.14620K562AQR
IGHMBP2ENSG00000132740.4975.979401252.63950-0.360003.341802.26880K562CELF1
IGHMBP2ENSG00000132740.4563.79590376.434700.582702.665801.41100K562EEF2
IGHMBP2ENSG00000132740.4574.32740363.634800.659304.899603.66900K562EFTUD2
IGHMBP2ENSG00000132740.4281.83060192.774900.547802.860402.05160K562EIF3G
IGHMBP2ENSG00000132740.4648.60230500.370400.374202.999502.37300K562FXR1
IGHMBP2ENSG00000132740.4112.44870232.47510-1.047805.735504.63410K562G3BP2
IGHMBP2ENSG00000132740.4482.95650355.724600.441002.286301.44400K562HNRNPM
IGHMBP2ENSG00000132740.4561.67030331.375500.761205.553703.89220K562IGF2BP2
IGHMBP2ENSG00000132740.4522.51330348.127900.585804.913003.78530K562MAGOH
IGHMBP2ENSG00000132740.4450.08290347.401200.373502.218701.39950K562MATR3
IGHMBP2ENSG00000132740.4509.40410688.44310-0.434502.521501.72820K562PCBP3
IGHMBP2ENSG00000132740.4396.54260528.07440-0.413302.875602.05880K562POLR2G
IGHMBP2ENSG00000132740.4491.60930353.861700.474202.480701.76990K562PRPF8
IGHMBP2ENSG00000132740.4579.17780338.238100.775908.640107.50830K562PTBP1
IGHMBP2ENSG00000132740.4872.758201182.29440-0.437904.464103.08110K562PUM1
IGHMBP2ENSG00000132740.4964.204301158.38200-0.264702.191001.33540K562PUM2
IGHMBP2ENSG00000132740.4884.04510664.874300.410903.026002.46200K562PUS1
IGHMBP2ENSG00000132740.4110.99740221.77130-0.998504.042602.27730K562RAVER1
IGHMBP2ENSG00000132740.4846.03660647.905700.384803.670203.00100K562RBM15
IGHMBP2ENSG00000132740.4535.04090324.256400.722406.558605.19360K562RBM22
IGHMBP2ENSG00000132740.4558.02540241.560601.2078018.1736015.80530K562SF3B4
IGHMBP2ENSG00000132740.4616.45100331.601300.8944010.431309.07320K562SRSF1
IGHMBP2ENSG00000132740.4443.00420313.209800.500103.127001.99970K562SRSF5
IGHMBP2ENSG00000132740.4493.07240335.569500.555103.790802.95650K562TARDBP
IGHMBP2ENSG00000132740.4472.31610323.703300.545002.160001.44420K562TIA1
IGHMBP2ENSG00000132740.4458.39430317.726300.528703.398002.16140K562TRA2A
IGHMBP2ENSG00000132740.4394.21360232.594200.761106.533005.30530K562U2AF2
IGHMBP2ENSG00000132740.4729.16640967.14920-0.407503.351502.39020K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IGHMBP2 is not available on ENCORE database.





2 RBPs can affect the splicing of IGHMBP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIGHMBP2ENSG00000132740.4chr11+686760016867609968675612686758056867890768678947-0.230000.000000.00000excludedHepG2U2AF2
A3SSIGHMBP2ENSG00000132740.4chr11+6869661168696825686966506869682568685144686853510.151000.005590.03191longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IGHMBP2 is not avaliable on ENCORE database.