EIF6

General Information

Gene Name       : EIF6
Gene ID             : ENSG00000242372.7
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EIF6)


Antibody Validation

 View validation images for all EIF6 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EIF6ENSG00000242372.755.81111.6583.73ENCSR000AEF
HepG2EIF6ENSG00000242372.7407.03247.00327.01ENCSR985KAT
K562EIF6ENSG00000242372.7208.16166.42187.29ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq EIF6-BGKcLV23-K562ENCSR975NHVEIF6K562ReleasedENCSR877JEM   CRISPRKD% = 60.0,59.4
knockdown followed by RNA-seq EIF6-BGHcLV24-HepG2ENCSR608WXKEIF6HepG2ReleasedENCSR671FDZ   CRISPRKD% = 68.8,68.4






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
EIF6ENCAB404EIOPA5-79197UK2881425BGHcLV24-29, Released, ENCODE4BGKcLV23-37, Released, ENCODE4
EIF63833S2Submitted, ENCORE2BGHcLV24-29, Released, ENCODE4BGKcLV23-37, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
EIF6K562CRISPRENCSR975NHVENCSR877JEMEIF6-BGKcLV23-37,EIF6-BGKcLV23-38NT-BGKcLV23-1,NT-BGKcLV23-260.0,59.4ReleasedENCODE4
EIF6K562CRISPRBGKcLV23-39,BGKcLV23-40BGKcLV23-1,BGKcLV23-249.0,57.3NotSatisfiedENCODE4
EIF6HepG2CRISPRENCSR608WXKENCSR671FDZEIF6-BGHcLV24-29,EIF6-BGHcLV24-30NT-BGHcLV24-1,NT-BGHcLV24-268.8,68.4ReleasedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
EIF6Product_ID: 3833S
Lot_ID: 2
Source: Cell Signaling Technology
Target Name: EIF6-human		 CST_3833S_2_EIF6.png<br>Caption: IP-WB analysis of 3833S whole cell lysate using the EIF6 specific antibody, 3833S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the EIF6-specific antibody, 3833S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 EIF6-K562-CRISPR-3833S.png<br>Caption: Western blot following CRISPR against EIF6 in K562 whole cell lysate using EIF6 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF6. EIF6 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
EIF6Product_ID: PA5-79197
Lot_ID: UK2881425
Source: Thermo Fisher
Target Name: EIF6-human		 EIF6-HEPG2-CRISPR-PA5-79197.png<br>Caption: Western blot following CRISPR against EIF6 in HepG2 whole cell lysate using EIF6 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF6. EIF6 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 EIF6-K562-CRISPR-PA5-79197.png<br>Caption: Western blot following CRISPR against EIF6 in K562 whole cell lysate using EIF6 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF6. EIF6 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for EIF6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EIF6 RNA is bound by 29 proteins.  







eCLIP assay for EIF6 is not avaliable on ENCORE database.





29 proteins are bound to EIF6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr203386694633866989-3'-UTR,intron-Distal3.0148812.79046HepG2RPS3
chr203386744633867505-3'-UTR,CDS,intron-Distal,intron-Proximal3.397975.06049HepG2ZC3H11A
chr203386736833867385-3'-UTR,CDS,intron-Distal,intron-Proximal3.826855.82560HepG2PABPN1
chr203386686233866941-3'-UTR,intron-Distal4.050436.75470HepG2UPF1
chr203386739133867425-3'-UTR,CDS,intron-Distal3.148784.81290HepG2DDX55
chr203386770833867747-3'-UTR,CDS,intron-Distal,intron-Proximal4.9172413.19443HepG2AQR
chr203386697333867043-3'-UTR,CDS,intron-Distal3.922564.57180HepG2AQR
chr203386746033867542-3'-UTR,CDS,intron-Distal,intron-Proximal3.2807410.99913HepG2LARP4
chr203386780333867890-3'-UTR,CDS,intron-Distal,intron-Proximal3.3740910.63716HepG2G3BP1
chr203386752033867610-3'-UTR,CDS,intron-Distal,intron-Proximal5.460659.57673HepG2AQR
chr203386774533867767-3'-UTR,CDS,intron-Distal3.3976510.17919HepG2PPIG
chr203386776233867805-3'-UTR,CDS,intron-Distal,intron-Proximal3.345206.22033HepG2RPS3
chr203386687833866931-3'-UTR,intron-Distal3.343967.22358HepG2PABPN1
chr203386750633867544-3'-UTR,CDS,intron-Distal,intron-Proximal3.761875.62335HepG2RPS3
chr203386689933866965-3'-UTR,intron-Distal3.9596317.03008K562PABPC4
chr203386699533867010-3'-UTR,CDS,intron-Distal4.614345.58993HepG2PABPN1
chr203386674833866787-3'-UTR,intron-Distal6.18748400.00000K562PABPC4
chr203386675833866843-3'-UTR,intron-Distal5.1571315.18786HepG2SUB1
chr203386678833866833-3'-UTR,intron-Distal5.0417578.75885K562PABPC4
chr203386675433866881-3'-UTR,intron-Distal3.3770210.20708HepG2AKAP1
chr203386770633867748-3'-UTR,CDS,intron-Distal,intron-Proximal4.340989.68074HepG2EFTUD2
chr203386750533867542-3'-UTR,CDS,intron-Distal,intron-Proximal4.966617.76900HepG2PABPN1
chr203386770433867757-3'-UTR,CDS,intron-Distal,intron-Proximal5.6105613.10719HepG2PRPF8
chr203386675433866859-3'-UTR,intron-Distal3.4094230.46801HepG2DDX55
chr203386771133867760-3'-UTR,CDS,intron-Distal,intron-Proximal3.1696012.19643HepG2BUD13
chr203386683333866860-3'-UTR,intron-Distal3.849618.40205K562PABPC4
chr203386779133867830-3'-UTR,CDS,intron-Distal,intron-Proximal4.913186.69987K562RPS3
chr203386679133866865-3'-UTR,intron-Distal4.4989715.89240HepG2PABPN1
chr203386746033867480-3'-UTR,CDS,intron-Distal,intron-Proximal3.143595.11600HepG2RPS3
chr203386682833866879-3'-UTR,intron-Distal3.8415717.61311HepG2LARP4
chr203386754233867589-3'-UTR,CDS,intron-Distal,intron-Proximal4.7634314.37547HepG2EFTUD2
chr203386675133866814-3'-UTR,intron-Distal3.7190510.94252K562IGF2BP2
chr203386675833866791-3'-UTR,intron-Distal3.866469.74915HepG2PABPN1
chr203386674133866826-3'-UTR,intron-Distal4.4850013.89495HepG2UPF1
chr203386738533867433-3'-UTR,CDS,intron-Distal3.229346.72814HepG2PABPN1
chr203386745133867495-3'-UTR,CDS,intron-Distal,intron-Proximal4.105387.55078HepG2PABPN1
chr203386694233866989-3'-UTR,intron-Distal4.5277210.94373K562RPS3
chr203386736033867377-3'-UTR,CDS,intron-Distal,intron-Proximal4.7727815.49797HepG2PRPF8
chr203386774633867786-3'-UTR,CDS,intron-Distal,intron-Proximal3.450088.80587HepG2GRWD1
chr203386675733866828-3'-UTR,intron-Distal4.5196637.27041HepG2LARP4
chr203386780533867915-3'-UTR,CDS,intron-Distal,intron-Proximal3.4988411.75294HepG2RPS3
chr203387226633872325-5'-UTR,CDS,intron-Distal,intron-Proximal5.0352715.34254HepG2AQR
chr203387235633872384-5'-UTR,intron-Distal,intron-Proximal3.8958122.91286HepG2SF3B4
chr203387237933872445-5'-UTR,intron-Distal,intron-Proximal3.2619825.66360HepG2EFTUD2
chr203387228833872380-5'-UTR,CDS,intron-Distal,intron-Proximal3.1870911.71019HepG2GTF2F1
chr203387227133872350-5'-UTR,CDS,intron-Distal,intron-Proximal3.504974.57435K562SF3B4
chr203387238433872437-5'-UTR,intron-Distal,intron-Proximal3.8367114.52638HepG2NCBP2
chr203387243733872454-5'-UTR,intron-Distal3.7589710.93919HepG2NCBP2
chr203387227133872321-5'-UTR,CDS,intron-Distal,intron-Proximal3.7766922.36710HepG2PRPF4
chr203387245433872470-5'-UTR,intron-Distal4.0639412.32968HepG2NCBP2
chr203387238633872396-5'-UTR,intron-Distal,intron-Proximal4.1033928.77132HepG2PRPF4
chr203387232133872354-5'-UTR,intron-Distal,intron-Proximal5.2556434.84336HepG2PRPF4
chr203387239633872404-5'-UTR,intron-Distal,intron-Proximal4.6767543.61144HepG2PRPF4
chr203387242633872473-5'-UTR,intron-Distal5.3291522.14081HepG2GTF2F1
chr203387239633872518-5'-UTR,intron-Distal,intron-Proximal3.2019030.60270HepG2CSTF2T
chr203387237533872477-5'-UTR,intron-Distal,intron-Proximal4.0711828.40225HepG2PCBP2
chr203387232633872390-5'-UTR,intron-Distal,intron-Proximal4.8872311.43968HepG2AQR
chr203387226033872356-5'-UTR,CDS,intron-Distal,intron-Proximal4.0043743.23754HepG2SF3B4
chr203387242533872459-5'-UTR,intron-Distal,intron-Proximal4.99013400.00000HepG2PRPF4
chr203387225333872299-5'-UTR,CDS,intron-Distal,intron-Proximal3.9934615.96989K562DDX3X
chr203387247433872515-5'-UTR,intron-Distal,intron-Proximal4.3829421.82839HepG2PRPF4
chr203387237833872386-5'-UTR,intron-Distal,intron-Proximal4.7048232.04188HepG2PRPF4
chr203387237033872378-5'-UTR,intron-Distal,intron-Proximal4.5312627.61954HepG2PRPF4
chr203387247033872526-5'-UTR,intron-Distal,intron-Proximal5.7226813.63931HepG2NCBP2
chr203387232533872489-5'-UTR,intron-Distal,intron-Proximal4.1531173.58049HepG2FAM120A
chr203387240933872438-5'-UTR,intron-Distal,intron-Proximal3.5530515.72462HepG2SF3B4
chr203387235833872421-5'-UTR,intron-Distal,intron-Proximal3.344383.94787K562AQR
chr203387252833872537-5'-UTR,intron-Distal,intron-Proximal3.433186.49064K562DDX3X
chr203387240633872467-5'-UTR,intron-Distal,intron-Proximal4.184558.84794HepG2AQR
chr203387235433872370-5'-UTR,intron-Distal,intron-Proximal5.0675534.06312HepG2PRPF4
chr203387238533872409-5'-UTR,intron-Distal,intron-Proximal3.5021217.53145HepG2SF3B4
chr203387236633872473-5'-UTR,intron-Distal,intron-Proximal4.629487.48569K562GTF2F1
chr203387241133872419-5'-UTR,intron-Distal,intron-Proximal5.0399953.50836HepG2PRPF4
chr203387235033872386-5'-UTR,intron-Distal,intron-Proximal3.022605.12317HepG2FUS
chr203387226433872322-5'-UTR,CDS,intron-Distal,intron-Proximal3.1112010.70261HepG2PRPF8
chr203387227433872342-5'-UTR,CDS,intron-Distal,intron-Proximal3.9757138.74511HepG2SF3A3
chr203387241633872517-5'-UTR,intron-Distal,intron-Proximal3.0212733.65504HepG2RBFOX2
chr203387246933872474-5'-UTR,intron-Distal4.2879217.69377HepG2PRPF4
chr203387246733872521-5'-UTR,intron-Distal,intron-Proximal4.592487.95190HepG2AQR
chr203387227433872348-5'-UTR,CDS,intron-Distal,intron-Proximal3.4946829.58570HepG2EFTUD2
chr203387247733872510-5'-UTR,intron-Distal,intron-Proximal3.345386.79343HepG2PCBP2
chr203387240433872411-5'-UTR,intron-Distal,intron-Proximal4.9161251.49553HepG2PRPF4
chr203387238033872426-5'-UTR,intron-Distal,intron-Proximal5.3987923.87492HepG2GTF2F1
chr203387227133872296-5'-UTR,CDS,intron-Distal,intron-Proximal3.008126.21779K562YBX3
chr203387253733872580-5'-UTR,intron-Distal,intron-Proximal3.531136.39699K562DDX3X
chr203387245933872469-5'-UTR,intron-Distal4.6649543.56328HepG2PRPF4
chr203386855433868607-CDS,intron-Distal3.5524310.83313K562YBX3
chr203387220533872238-CDS,intron-Distal5.203474.66990HepG2DDX3X
chr203387207333872118-CDS,intron-Distal,intron-Proximal5.321169.24251HepG2EFTUD2
chr203387201933872047-CDS,intron-Distal3.6606816.88773HepG2PPIG
chr203387220533872238-CDS,intron-Distal3.3352912.57041HepG2PPIG
chr203387194033872005-CDS,intron-Distal,intron-Proximal3.5488734.44475HepG2PRPF8
chr203386848933868541-CDS,intron-Distal,intron-Proximal3.185135.88048HepG2G3BP1
chr203386860733868631-CDS,intron-Distal3.352096.00087K562YBX3
chr203386845933868489-CDS,intron-Distal,intron-Proximal3.272434.96885HepG2G3BP1
chr203387197733872019-CDS,intron-Distal,intron-Proximal3.5470131.28771HepG2PPIG
chr203387219333872253-CDS,intron-Distal3.4911016.05387K562DDX3X
chr203387213933872192-CDS,intron-Distal,intron-Proximal3.3585316.61898HepG2PRPF8
chr203387189233871928-intron-Distal,intron-Proximal4.3566311.64444HepG2EFTUD2
chr203386732433867360-intron-Distal,intron-Proximal5.6798824.20385HepG2PRPF8
chr203386732633867368-intron-Distal,intron-Proximal5.106498.23509HepG2AQR
chr203386701333867102-intron-Distal3.865595.34167HepG2SF3B4
chr203386725233867358-intron-Distal,intron-Proximal5.1965821.60331HepG2EFTUD2
chr203386728533867369-intron-Distal,intron-Proximal5.9692111.65826K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EIF6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EIF6 is not available on ENCORE database.

  • 81 RBPs can affect the levels of EIF6.  








The Knockdown/knockout RNA-Seq assay for EIF6 is not available on ENCORE database.





81 RBPs can affect the gene expression of EIF6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EIF6ENSG00000242372.21584.309702266.09980-0.516406.223804.68430HepG2AATF
EIF6ENSG00000242372.22758.444203274.28870-0.247302.130901.58280HepG2ACO1
EIF6ENSG00000242372.24143.151405945.77390-0.521104.923604.24130HepG2AKAP1
EIF6ENSG00000242372.21897.26840889.348601.0930022.0700020.63420HepG2BOP1
EIF6ENSG00000242372.21025.367701338.42730-0.384403.656902.78700HepG2CALR
EIF6ENSG00000242372.22943.353002098.145600.488209.233007.40250HepG2YBX3
EIF6ENSG00000242372.25138.497704393.434800.225904.755203.82350HepG2DAZAP1
EIF6ENSG00000242372.22615.944402101.115300.316104.080602.69470HepG2DDX1
EIF6ENSG00000242372.24722.564405695.11170-0.270201.869701.34500HepG2DDX3X
EIF6ENSG00000242372.23761.958404893.37240-0.379302.877702.24900HepG2DDX6
EIF6ENSG00000242372.22736.125402042.001700.4221010.709609.52410HepG2DNAJC2
EIF6ENSG00000242372.21687.703302301.96720-0.447803.080801.90360HepG2AGO1
EIF6ENSG00000242372.22332.609804702.97260-1.0116018.7428017.29940HepG2EIF2S1
EIF6ENSG00000242372.22361.568403325.85520-0.494006.983905.77070HepG2FUBP3
EIF6ENSG00000242372.23641.876404864.63700-0.417703.589502.83570HepG2G3BP1
EIF6ENSG00000242372.21752.625602298.31320-0.391106.112505.24170HepG2HNRNPU
EIF6ENSG00000242372.23557.149702914.908000.287202.981202.23230HepG2IGF2BP1
EIF6ENSG00000242372.22434.132204641.44760-0.931204.117702.92210HepG2IGF2BP3
EIF6ENSG00000242372.23330.046304973.89210-0.578805.089103.69250HepG2KHSRP
EIF6ENSG00000242372.24448.211005400.00140-0.279701.916501.38420HepG2NCBP2
EIF6ENSG00000242372.22991.430404808.03520-0.684609.031407.74560HepG2PABPC4
EIF6ENSG00000242372.23381.787505047.10600-0.5777018.1361016.80060HepG2PCBP1
EIF6ENSG00000242372.21781.896702413.26770-0.437602.455001.47540HepG2PCBP2
EIF6ENSG00000242372.22416.349702049.916800.237202.498401.79400HepG2PPIL4
EIF6ENSG00000242372.21504.722601935.36520-0.363102.594101.84350HepG2PRPF4
EIF6ENSG00000242372.23037.274705135.70320-0.7578028.6486027.25160HepG2PTBP1
EIF6ENSG00000242372.23670.978805561.91410-0.5994014.2339012.97360HepG2QKI
EIF6ENSG00000242372.22054.253702498.48120-0.282402.902002.02600HepG2RBM15
EIF6ENSG00000242372.24444.180705620.48320-0.338804.639404.01330HepG2RBM22
EIF6ENSG00000242372.23375.617605047.86230-0.5805010.356409.11150HepG2RBM25
EIF6ENSG00000242372.22832.706605715.47470-1.0127052.1497050.49520HepG2NELFE
EIF6ENSG00000242372.23391.651605323.31470-0.6503023.1248021.64800HepG2RECQL
EIF6ENSG00000242372.21778.909902471.38110-0.474304.470203.49770HepG2RRP9
EIF6ENSG00000242372.23570.365005346.77910-0.5826018.6261017.30610HepG2SF3B4
EIF6ENSG00000242372.2699.18210972.59180-0.476202.400801.67520HepG2SNRNP70
EIF6ENSG00000242372.23434.633306348.03920-0.8862050.2304048.79390HepG2SRFBP1
EIF6ENSG00000242372.23862.264805580.94140-0.5311017.4929016.51880HepG2SRSF1
EIF6ENSG00000242372.22601.622704540.44610-0.8034034.9836033.44640HepG2SRSF9
EIF6ENSG00000242372.22974.271505016.53860-0.7542014.0109012.89250HepG2TAF15
EIF6ENSG00000242372.23526.064404609.33430-0.386505.220004.08550HepG2TIA1
EIF6ENSG00000242372.23271.713602137.943900.6137018.7906017.44250HepG2UTP3
EIF6ENSG00000242372.21448.888902290.64930-0.660804.549002.91660HepG2XRCC5
EIF6ENSG00000242372.21466.020601909.96180-0.381602.765002.09300HepG2ZC3H8
EIF6ENSG00000242372.21750.545101422.406100.299403.687803.04960K562AGGF1
EIF6ENSG00000242372.2587.86210975.43880-0.730608.161306.09260K562CCAR1
EIF6ENSG00000242372.22395.330101658.496400.5302011.6740010.43480K562DDX47
EIF6ENSG00000242372.2695.399401091.93410-0.651006.797104.60040K562DHX30
EIF6ENSG00000242372.2715.844001048.95440-0.551204.605602.85050K562DNAJC21
EIF6ENSG00000242372.21144.173101435.79670-0.327504.049002.56820K562EIF2S1
EIF6ENSG00000242372.21575.77460902.207000.8044016.7209014.68870K562EIF3G
EIF6ENSG00000242372.23100.713303662.86580-0.240402.768901.83140K562EIF4G2
EIF6ENSG00000242372.21495.982701192.095800.327502.764901.47650K562EWSR1
EIF6ENSG00000242372.2684.114601208.96300-0.821503.727602.39280K562FKBP4
EIF6ENSG00000242372.2317.36900450.93280-0.506802.791301.87300K562FTO
EIF6ENSG00000242372.22085.059001420.260700.5538010.628009.52780K562FXR1
EIF6ENSG00000242372.2219.68510741.87820-1.7557012.5570010.82210K562G3BP2
EIF6ENSG00000242372.22139.383302639.88540-0.303302.275001.30550K562HNRNPA1
EIF6ENSG00000242372.2788.871201390.81810-0.818107.671606.72440K562HNRNPC
EIF6ENSG00000242372.21903.073201498.808100.344403.293002.12900K562HNRNPL
EIF6ENSG00000242372.2657.58720984.98330-0.582905.438103.35470K562KHDRBS1
EIF6ENSG00000242372.21419.060501670.39900-0.235303.219302.41940K562NSUN2
EIF6ENSG00000242372.21259.38660660.822600.930305.200303.72460K562PABPN1
EIF6ENSG00000242372.2883.067201758.92960-0.994108.287406.84960K562PCBP3
EIF6ENSG00000242372.2869.088201349.24570-0.634604.500403.47620K562POLR2G
EIF6ENSG00000242372.21849.896001145.199000.691703.777002.79680K562PPIG
EIF6ENSG00000242372.21333.26440785.646600.762903.265301.62760K562PPP1R8
EIF6ENSG00000242372.22164.638201661.048900.381903.206602.39830K562PRPF8
EIF6ENSG00000242372.21913.256101314.629100.541304.560903.72850K562PTBP1
EIF6ENSG00000242372.21759.051501467.881900.261001.943801.47340K562PUS1
EIF6ENSG00000242372.21639.659701259.946300.379902.308401.54580K562RBM22
EIF6ENSG00000242372.21135.67770604.340300.910003.909902.40320K562SF1
EIF6ENSG00000242372.2347.65230474.77510-0.449602.152101.30560K562SF3B1
EIF6ENSG00000242372.21042.51520771.017500.435102.139001.38790K562SF3B4
EIF6ENSG00000242372.21485.32270736.759701.011405.541403.41790K562SFPQ
EIF6ENSG00000242372.2697.889901074.47230-0.622606.635204.67960K562SLBP
EIF6ENSG00000242372.21431.667701688.64380-0.238202.977202.01300K562SRPK2
EIF6ENSG00000242372.21295.649201781.32770-0.459307.198905.30370K562SRSF7
EIF6ENSG00000242372.21051.811601535.86990-0.546203.578601.83330K562SRSF9
EIF6ENSG00000242372.2746.00830930.64450-0.319002.641401.39620K562SSB
EIF6ENSG00000242372.21242.599601607.91780-0.371802.630901.64080K562SUPV3L1
EIF6ENSG00000242372.21744.861701353.208800.366602.983202.12650K562SYNCRIP
EIF6ENSG00000242372.2342.61250728.20710-1.087803.268601.62720K562TAF15
EIF6ENSG00000242372.2495.79420718.66520-0.535603.303602.08720K562U2AF1
EIF6ENSG00000242372.2456.00060742.37390-0.703108.581707.15250K562U2AF2
EIF6ENSG00000242372.21305.573601701.95140-0.382503.169002.07630K562UCHL5
EIF6ENSG00000242372.21214.690301515.52640-0.319202.814001.92970K562WDR3
EIF6ENSG00000242372.23006.342603852.90840-0.357904.124302.54170K562WRN
EIF6ENSG00000242372.22491.393003663.92700-0.556408.138006.53590K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EIF6 is not available on ENCORE database.





32 RBPs can affect the splicing of EIF6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.090000.000620.01412excludedK562SRSF1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.116000.000000.00017excludedK562PRPF8
SEEIF6ENSG00000242372.2chr20-3386845633868625338677443386792133871978338722950.091000.000100.01002includedHepG2RBM22
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.081000.000050.00750excludedHepG2PRPF8
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.119000.000000.00035excludedK562XRCC6
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.095000.000040.01991excludedK562WDR43
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.059000.000310.01012excludedHepG2HNRNPK
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.076000.000000.00103excludedHepG2DDX3X
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.081000.000780.05945excludedK562SUPV3L1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.068000.000040.00462excludedHepG2NCBP2
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.143000.000140.01443excludedHepG2FTO
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872211-0.065000.000130.03429excludedK562APOBEC3C
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.113000.000000.00057excludedK562EFTUD2
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387218333872295-0.058000.000010.00078excludedHepG2MATR3
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.071000.000450.05409excludedHepG2PCBP2
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.118000.000000.00000excludedHepG2SRSF1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.145000.000000.00000excludedHepG2TIAL1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.085000.000110.07203excludedK562LARP7
SEEIF6ENSG00000242372.2chr20-338684563386862533867744338679213387197833872295-0.184000.000000.00003excludedHepG2SUPV3L1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.064000.000640.03408excludedHepG2PCBP1
SEEIF6ENSG00000242372.2chr20-338684563386862533867744338679213387197833872295-0.127000.000050.01558excludedHepG2DDX55
SEEIF6ENSG00000242372.2chr20-338684563386862533867744338679213387197833872295-0.158000.000060.03877excludedHepG2SMNDC1
SEEIF6ENSG00000242372.2chr20-338684563386862533867744338679213387197833872295-0.162000.000000.00041excludedHepG2XRN2
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.065000.002510.07851excludedHepG2HNRNPC
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.105000.000080.00516excludedK562PTBP1
SEEIF6ENSG00000242372.2chr20-338684563386863233867744338679213387197833872295-0.099000.000020.00059excludedK562HNRNPC
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.198000.000230.00687includedHepG2PCBP2
RIEIF6ENSG00000242372.2chr20-3387197833872295338719783387206433872183338722950.124000.000000.00000includedHepG2U2AF2
RIEIF6ENSG00000242372.2chr20-3387197833872295338719783387206433872183338722950.060000.000000.00000includedK562PRPF8
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.092000.002920.05244includedHepG2IGF2BP3
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.072000.002480.06827includedHepG2MATR3
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.098000.003560.06855includedHepG2SRSF1
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.151000.000000.00001includedHepG2SF3B4
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.117000.000070.00141includedHepG2RBM22
RIEIF6ENSG00000242372.2chr20-3387218333872505338721833387229533872499338725050.150000.000030.02268includedHepG2IGF2BP1
RIEIF6ENSG00000242372.2chr20-3387197833872295338719783387206433872183338722950.090000.000000.00000includedK562EFTUD2
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.206000.000000.000001includedHepG2FTO
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.101000.001060.035231includedK562UCHL5
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872079338677443386792133872183338722950.121000.000000.000021includedHepG2SRSF1
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197833872064338677443386792133872183338722950.096000.002300.036611includedK562SRSF1
MXEEIF6ENSG00000242372.2chr20-3387198633872064338721833387223633867744338679213387252833872607-0.142000.001660.014182includedK562AQR
MXEEIF6ENSG00000242372.2chr20-3386845633868632338719783387206433867744338679213387218333872295-0.135000.002650.034602includedK562U2AF2
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197333872064338677443386792133872183338722950.077000.002780.083941includedHepG2BCCIP
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197833872064338677443386792133872183338722950.079000.001280.051561includedHepG2BCCIP
MXEEIF6ENSG00000242372.2chr20-33868456338686253387198633872064338677443386792133872183338722950.080000.002850.064191includedHepG2XRN2
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197833872064338677443386792133872183338722950.090000.000220.010831includedHepG2XRN2
MXEEIF6ENSG00000242372.2chr20-33868456338686323387198633872064338677443386792133872183338722950.079000.003310.070511includedHepG2XRN2
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.087000.000630.023711includedHepG2XRN2
MXEEIF6ENSG00000242372.2chr20-33868456338686253387198633872064338677443386792133872183338722950.115000.000010.000551includedHepG2DDX55
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197833872064338677443386792133872183338722950.113000.000000.000151includedHepG2DDX55
MXEEIF6ENSG00000242372.2chr20-33868456338686323387198633872064338677443386792133872183338722950.114000.000010.000661includedHepG2DDX55
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.111000.000010.000451includedHepG2DDX55
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.107000.000740.049911includedK562TRA2A
MXEEIF6ENSG00000242372.2chr20-3386845633868632338719783387206433867744338679213387218333872295-0.119000.000190.011302includedK562DDX55
MXEEIF6ENSG00000242372.2chr20-33868456338686253387197833872064338677443386792133872183338722950.105000.000020.001331includedHepG2SUPV3L1
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.105000.000030.002141includedHepG2SUPV3L1
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.116000.000280.009691includedK562SUPV3L1
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.149000.001090.024711includedK562HNRNPUL1
MXEEIF6ENSG00000242372.2chr20-33868456338686323387197833872064338677443386792133872183338722950.098000.001860.085731includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EIF6 is not avaliable on ENCORE database.