EIF4ENIF1

General Information

Gene Name       : EIF4ENIF1
Gene ID             : ENSG00000184708.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EIF4ENIF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EIF4ENIF1ENSG00000184708.1749.1529.7339.44ENCSR000AEF
HepG2EIF4ENIF1ENSG00000184708.1714.2515.8315.04ENCSR985KAT
K562EIF4ENIF1ENSG00000184708.1711.2916.7414.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
EIF4ENIF1A300-706A1BGKcLV38-61, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
EIF4ENIF1K562CRISPREIF4ENIF1-BGKcLV38-61,EIF4ENIF1-BGKcLV38-62NT-BGKcLV38-1,NT-BGKcLV38-271.7,81.0SubmittingENCORE2
EIF4ENIF1HepG2CRISPRBGHcLV41-35,BGHcLV41-36BGHcLV41-1,BGHcLV41-2no band on the position,NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
EIF4ENIF1Product_ID: A300-706A
Lot_ID: 1
Source: Bethyl Labs
Target Name: EIF4ENIF1-human		 EIF4ENIF1-K562-CRISPR-A300-706A.png<br>Caption: Western blot following CRISPR against EIF4ENIF1 in K562 whole cell lysate using EIF4ENIF1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF4ENIF1. EIF4ENIF1 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for EIF4ENIF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EIF4ENIF1 RNA is bound by 13 proteins.  







eCLIP assay for EIF4ENIF1 is not avaliable on ENCORE database.





13 proteins are bound to EIF4ENIF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223183781431837913-3'-UTR,CDS,intron-Distal4.887524.17937HepG2PCBP2
chr223186421431864297-3'-UTR,CDS,intron-Distal,intron-Proximal4.265504.11693K562BUD13
chr223183546031835559-3'-UTR,intron-Distal,intron-Proximal6.1540921.35262K562PUM2
chr223183537631835400-3'-UTR,intron-Distal6.143995.13070K562PUM2
chr223183555931835621-3'-UTR,intron-Distal,intron-Proximal5.5493010.55912K562PUM2
chr223183780831837881-3'-UTR,CDS,intron-Distal3.668133.14999HepG2GRWD1
chr223183902831839091-3'-UTR,CDS,intron-Distal,intron-Proximal3.977615.99890HepG2U2AF2
chr223183562131835685-3'-UTR,intron-Distal,intron-Proximal6.269766.46573K562PUM2
chr223188567831885781-5'-UTR,intron-Distal,intron-Proximal4.031885.03370HepG2NCBP2
chr223188567931885772-5'-UTR,intron-Distal,intron-Proximal3.542514.06757K562UCHL5
chr223188471531884732-5'-UTR,intron-Distal,intron-Proximal3.393963.32039HepG2PPIG
chr223188468231884732-5'-UTR,CDS,intron-Distal,intron-Proximal4.264313.59941K562UCHL5
chr223188461431884714-5'-UTR,CDS,intron-Distal5.308005.93845K562DDX24
chr223185012731850185-CDS,intron-Distal,intron-Proximal3.842093.34184HepG2GRWD1
chr223185900531859112-CDS,intron-Distal4.020294.13344K562GRWD1
chr223185453331854632-CDS,intron-Distal4.076436.92541HepG2PPIG
chr223185012931850211-CDS,intron-Distal,intron-Proximal3.302114.14618K562ZNF622
chr223185190131851972-CDS,intron-Distal3.456175.95375K562ZNF622
chr223185895531859116-CDS,intron-Distal3.897215.56491HepG2BCLAF1
chr223185454831854632-CDS,intron-Distal3.664683.05298K562GRWD1
chr223188462031884682-CDS,intron-Distal3.581814.76274K562UCHL5
chr223187539531875414-intron-Distal5.4433916.91987HepG2PRPF8
chr223187541431875428-intron-Distal5.4433916.91987HepG2PRPF8
chr223187538731875430-intron-Distal4.885936.75234K562PRPF8
chr223187540131875429-intron-Distal5.089653.90539HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EIF4ENIF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EIF4ENIF1 is not available on ENCORE database.

  • 32 RBPs can affect the levels of EIF4ENIF1.  








The Knockdown/knockout RNA-Seq assay for EIF4ENIF1 is not available on ENCORE database.





32 RBPs can affect the gene expression of EIF4ENIF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EIF4ENIF1ENSG00000184708.13357.78390526.95440-0.558602.518301.79020HepG2CNOT7
EIF4ENIF1ENSG00000184708.13496.69100679.97920-0.453103.006102.29290HepG2CPSF6
EIF4ENIF1ENSG00000184708.13474.76110366.848400.371902.015201.33540HepG2FUBP3
EIF4ENIF1ENSG00000184708.13579.87550770.83540-0.410702.332301.74120HepG2GPKOW
EIF4ENIF1ENSG00000184708.13450.96870632.40260-0.487804.876804.00050HepG2HNRNPL
EIF4ENIF1ENSG00000184708.13545.38660735.62000-0.431702.710502.08640HepG2HNRNPLL
EIF4ENIF1ENSG00000184708.13779.40080607.505700.359401.953801.41670HepG2NCBP2
EIF4ENIF1ENSG00000184708.13818.93130650.933800.331102.608801.85590HepG2PRPF4
EIF4ENIF1ENSG00000184708.13715.83490578.153200.308102.023901.47720HepG2QKI
EIF4ENIF1ENSG00000184708.13780.09670594.094300.392903.500802.90760HepG2NELFE
EIF4ENIF1ENSG00000184708.13578.92520779.86800-0.429903.070902.35710HepG2RPLP0
EIF4ENIF1ENSG00000184708.131050.34390735.041400.514903.045802.33790HepG2SF3A3
EIF4ENIF1ENSG00000184708.13715.80920555.786200.364903.001602.38930HepG2SF3B4
EIF4ENIF1ENSG00000184708.13754.66020580.115400.379403.271802.76830HepG2SRSF1
EIF4ENIF1ENSG00000184708.13893.35970737.996400.275502.439401.84780HepG2SUCLG1
EIF4ENIF1ENSG00000184708.13705.37590521.416200.435903.959203.30750HepG2TAF15
EIF4ENIF1ENSG00000184708.13311.05180457.18320-0.555605.045304.32950HepG2TRIM56
EIF4ENIF1ENSG00000184708.13972.78440681.621800.513004.173703.40970HepG2U2AF1
EIF4ENIF1ENSG00000184708.13791.13390629.354600.329902.981202.36390HepG2UTP3
EIF4ENIF1ENSG00000184708.13514.66340642.41470-0.319902.721502.05490HepG2ZC3H8
EIF4ENIF1ENSG00000184708.13868.25880716.931700.276202.694802.15320HepG2ZNF622
EIF4ENIF1ENSG00000184708.131148.17340904.018700.344803.862403.11070K562DDX47
EIF4ENIF1ENSG00000184708.13714.63990930.00510-0.380002.878002.10910K562GRSF1
EIF4ENIF1ENSG00000184708.13776.42510620.841400.322502.499101.64930K562HNRNPU
EIF4ENIF1ENSG00000184708.13780.40040580.583600.426602.153601.39770K562NAA15
EIF4ENIF1ENSG00000184708.13835.76780705.747200.243902.014201.36570K562NSUN2
EIF4ENIF1ENSG00000184708.131473.09740652.668401.174305.345303.84040K562PABPN1
EIF4ENIF1ENSG00000184708.131342.53850690.979200.9581013.8615012.69080K562PUS1
EIF4ENIF1ENSG00000184708.13622.21000481.048700.371102.341301.35140K562SAFB
EIF4ENIF1ENSG00000184708.131131.83000685.426700.723503.184401.82970K562SNRNP200
EIF4ENIF1ENSG00000184708.13562.47100438.313000.359702.284901.63490K562SRSF1
EIF4ENIF1ENSG00000184708.13739.50080541.552800.449303.868202.89540K562SYNCRIP
EIF4ENIF1ENSG00000184708.13847.05600665.801600.347303.537702.58890K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EIF4ENIF1 is not available on ENCORE database.





2 RBPs can affect the splicing of EIF4ENIF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSEIF4ENIF1ENSG00000184708.13chr22-3184341131843554318434113184355131844138318442180.432000.000160.09550longerHepG2DDX3X
MXEEIF4ENIF1ENSG00000184708.13chr22-3185966631859953318641603186428831854460318546363186782931867903-0.088000.012680.076762includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EIF4ENIF1 is not avaliable on ENCORE database.